KEGG   ENZYME: 4.1.1.74Help
Entry
EC 4.1.1.74                 Enzyme                                 

Name
indolepyruvate decarboxylase;
indol-3-yl-pyruvate carboxy-lyase;
3-(indol-3-yl)pyruvate carboxy-lyase
Class
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
BRITE hierarchy
Sysname
3-(indol-3-yl)pyruvate carboxy-lyase [(2-indol-3-yl)acetaldehyde-forming]
Reaction(IUBMB)
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO2 [RN:R01974]
Reaction(KEGG)
Substrate
3-(indol-3-yl)pyruvate [CPD:C00331]
Product
2-(indol-3-yl)acetaldehyde [CPD:C00637];
CO2 [CPD:C00011]
Comment
Thiamine diphosphate- and Mg2+-dependent. More specific than EC 4.1.1.1 pyruvate decarboxylase
History
EC 4.1.1.74 created 1999
Pathway
ec00380  Tryptophan metabolism
ec01100  Metabolic pathways
Orthology
K04103  indolepyruvate decarboxylase
Genes
STY: STY2646
STT: t0452
SEX: STBHUCCB_4850
SENT: TY21A_02305
STM: STM2405
SEO: STM14_2958
SEV: STMMW_24291
SEY: SL1344_2373
SEM: STMDT12_C24280
SEJ: STMUK_2436
SENI: CY43_12870
SPT: SPA0455
SEK: SSPA0422
SEI: SPC_1250
SEC: SCH_2408(dciP)
SHB: SU5_03012
SENS: Q786_11880
SEG: SG2441
SEL: SPUL_0473
SET: SEN2391
SENA: AU38_12100
SENO: AU37_12115
SENV: AU39_12115
SENQ: AU40_13575
SENL: IY59_12435
SENE: IA1_12005
SBG: SBG_2213
SBZ: A464_2540
ENC: ECL_03728
ECLO: ENC_38590
EEC: EcWSU1_03228(ipdC)
ECLX: LI66_15680
ECLY: LI62_17180
ECLZ: LI64_15110
ECAN: CWI88_06420(ipdC)
ESA: ESA_00851
CSK: ES15_1112(ipdC)
CTU: CTU_29970(ipdC)
KPN: KPN_02740
KPU: KP1_3993
KPP: A79E_1361
KPT: VK055_4773(ipdC)
KPE: KPK_1400(ipdC)
KPR: KPR_1964(ipdC)
KPJ: N559_1511
KPX: PMK1_00237(ipdC)
KPNU: LI86_07355
KPNK: BN49_3956(ipdC)
KVA: Kvar_1310
KOX: KOX_26745
KOE: A225_4252
EAE: EAE_00275
EAR: CCG28866
CKO: CKO_00409
CRO: ROD_28081
CAMA: F384_13285
LEI: C2U54_21570(ipdC)
LEH: C3F35_18455(ipdC)
LNI: CWR52_19090(ipdC)
LEW: DAI21_11595(ipdC)
EBF: D782_1263
PSTS: E05_18610
YEN: YE1222(ipdC)
YEY: Y11_00891
YEW: CH47_624(ipdC)
YET: CH48_396
YEE: YE5303_09771(ipdC)
YRO: CH64_1327
SPE: Spro_3412
SRL: SOD_c33270(ipdC)
SPLY: Q5A_018035(ipdC_2)
SMAF: D781_3193
SMAR: SM39_3023
RAA: Q7S_05405
ECA: ECA3605(ipdC)
PATR: EV46_17890
PATO: GZ59_36300(ipdC)
PCT: PC1_3426
ETA: ETA_11130(ipdC)
EPY: EpC_11610(ipdC)
EPR: EPYR_01238(pdc)
EAM: EAMY_2469(pdc3)
EAY: EAM_2375(ipdC)
EBI: EbC_32520(ipdC)
ERJ: EJP617_35260(ipdC)
PAM: PANA_2745(ipdC)
PLF: PANA5342_1305(ipdC)
PAJ: PAJ_2029(ipdC)
PVA: Pvag_2180(ipdC)
PAGG: AL522_17970(ipdC)
PMR: PMI0845(ipdC)
PMIB: BB2000_0963(ipdC)
PRG: RB151_020410(ipdC)
PHEI: NCTC12003_00975(ipdC_1) NCTC12003_02564(ipdC_2)
MMK: MU9_3137
ETR: ETAE_1930
ETD: ETAF_1742
ETE: ETEE_4006(ipdC)
PSHI: SAMEA2665130_1032(ipdC)
PEN: PSEEN2115
SWP: swp_0601
SAGA: M5M_04875
FTU: FTT_1744c(ipdC)
FTQ: RO31_2075
FTF: FTF1744c(ipdC)
FTW: FTW_1982
FTT: FTV_1661(ipdC)
FTG: FTU_1746(ipdC)
FTL: FTL_0006
FTS: F92_00035
FTC: DA46_736
FTV: CH67_257
FTZ: CH68_2141
FTM: FTM_1730(idpC)
FTN: FTN_0116(ipdC)
FTX: AW25_84
FTD: AS84_598
FTY: CH70_10
FPT: BZ13_1316
FPI: BF30_920
FPM: LA56_1459
FPX: KU46_635
FPZ: LA55_89
FPJ: LA02_567
HCH: HCH_01981
RFR: Rfer_0518
SIMP: C6571_06705(ipdC)
MASZ: C9I28_16430(ipdC)
MASY: DPH57_05430(ipdC)
EBA: ebA6545(pdc)
AZA: AZKH_2996(ipdC)
TCL: Tchl_0074
DVM: DvMF_0027
DDE: Dde_2331
DMA: DMR_26260
DAS: Daes_0883
DPS: DP2330
SMD: Smed_5992
BRA: BRADO7016(ipdC)
BBT: BBta_0512(ipdC)
AOL: S58_04790
BRO: BRAD285_7156(ipdC)
RPA: RPA3116(ipdC)
RPB: RPB_2425
RPD: RPD_3027
RPT: Rpal_3526
SNO: Snov_3860
BID: Bind_1794
ERR: DVR09_08065(ipdC)
RRU: Rru_A2719
RRF: F11_13965
ABS: AZOBR_40354(ipdC)
AZT: TSH58p_08865(ipdC)
BWW: bwei_2395(PDC5)
BMYC: DJ92_4749
CPAS: Clopa_0520
CPAT: CLPA_c04400(kdc)
CPAE: CPAST_c04400(kdc)
MPE: MYPE6890(MYPE6890)
CAR: cauri_0131(pdc)
KRA: Krad_0182
SAQ: Sare_0838
SYG: sync_1491
SYX: SynWH7803_0869(pdc)
SYND: KR52_11410
SACI: Sinac_1424
CPI: Cpin_1754
MUC: MuYL_0601
FJO: Fjoh_3836
MOX: DAMO_2518(ipdC)
MAC: MA_0594(ipdC)
MBAR: MSBR2_1907
MBAK: MSBR3_2046
MTHE: MSTHC_1175
MTHR: MSTHT_2109
MHOR: MSHOH_3634
 » show all
Taxonomy
Reference
1  [PMID:7766676]
  Authors
Koga J.
  Title
Structure and function of indolepyruvate decarboxylase, a key enzyme in indole-3-acetic acid biosynthesis.
  Journal
Biochim Biophys Acta 1249:1-13 (1995)
DOI:10.1016/0167-4838(95)00011-I
Other DBs
ExplorEnz - The Enzyme Database: 4.1.1.74
IUBMB Enzyme Nomenclature: 4.1.1.74
ExPASy - ENZYME nomenclature database: 4.1.1.74
BRENDA, the Enzyme Database: 4.1.1.74
CAS: 9074-92-4

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