KEGG   ENZYME: 4.1.2.34Help
Entry
EC 4.1.2.34                 Enzyme                                 

Name
4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase;
2'-carboxybenzalpyruvate aldolase;
(3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-carboxybenzaldehyde-lyase;
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
BRITE hierarchy
Sysname
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate 2-formylbenzoate-lyase (pyruvate-forming)
Reaction(IUBMB)
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate + H2O = 2-formylbenzoate + pyruvate [RN:R07713]
Reaction(KEGG)
R07713;
(other) R03465
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Substrate
(3Z)-4-(2-carboxyphenyl)-2-oxobut-3-enoate [CPD:C16149];
H2O [CPD:C00001]
Product
2-formylbenzoate [CPD:C03057];
pyruvate [CPD:C00022]
Comment
Involved, with EC 1.13.11.38 (1-hydroxy-2-naphthoate 1,2-dioxygenase), in the metabolism of phenanthrene in bacteria.
History
EC 4.1.2.34 created 1989
Pathway
ec00624  Polycyclic aromatic hydrocarbon degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K11949  4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase
Genes
MMC: Mmcs_1629
MKM: Mkms_1655
MJL: Mjls_1602
MYE: AB431_15660
MVA: Mvan_0469
MGI: Mflv_0588 Mflv_0676
MSP: Mspyr1_01480
MRH: MycrhN_3149
APN: Asphe3_22010
Taxonomy
Reference
1  [PMID:6833175]
  Authors
Barnsley EA.
  Title
Phthalate pathway of phenanthrene metabolism: formation of 2'-carboxybenzalpyruvate.
  Journal
J Bacteriol 154:113-7 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.34
IUBMB Enzyme Nomenclature: 4.1.2.34
ExPASy - ENZYME nomenclature database: 4.1.2.34
UM-BBD (Biocatalysis/Biodegradation Database): 4.1.2.34
BRENDA, the Enzyme Database: 4.1.2.34
CAS: 86611-90-7

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