KEGG   ENZYME: 4.2.1.101Help
Entry
EC 4.2.1.101                Enzyme                                 

Name
trans-feruloyl-CoA hydratase;
trans-feruloyl-CoA hydro-lyase (incorrect);
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (trans-feruloyl-CoA-forming)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA hydro-lyase (feruloyl-CoA-forming)
Reaction(IUBMB)
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA = feruloyl-CoA + H2O [RN:R05772]
Reaction(KEGG)
Substrate
4-hydroxy-3-methoxyphenyl-beta-hydroxypropanoyl-CoA [CPD:C07303]
Product
feruloyl-CoA [CPD:C00406];
H2O [CPD:C00001]
History
EC 4.2.1.101 created 2000
Pathway
ec00360  Phenylalanine metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K18383  trans-feruloyl-CoA hydratase / vanillin synthase
Genes
XCC: XCC0810(fadB)
XCB: XC_3420
XCA: xcc-b100_3542(ech4)
XCP: XCR_0990
XCV: XCV0918(paaF)
XAX: XACM_0864(paaF)
XAC: XAC0883(fadB)
XCI: XCAW_03697(caiD)
XCT: J151_01010
XCJ: J158_01007
XOO: XOO3728(fadB)
XOM: XOO3520(XOO3520)
XOP: PXO_04626
XOR: XOC_0934
XAL: XALC_3045
XPH: XppCFBP6546_07095(XppCFBP6546P_07095)
PPU: PP_3358
PPF: Pput_2400
PSB: Psyr_2728
PSYR: N018_13590
PPRO: PPC_3628(paaG)
PFS: PFLU_3300
PSES: PSCI_1563(paaG)
PSEM: TO66_18490
PSOS: POS17_3613(paaG)
AVN: Avin_14230(ech)
AVL: AvCA_14230(ech)
AVD: AvCA6_14230(ech)
ACX: Achr_28510(ech)
ACB: A1S_1111
ABY: ABAYE2628(hcaA)
ABN: AB57_1195
ABAZ: P795_11770
ABAU: IX87_05290
ABAA: IX88_07805
ACC: BDGL_000391(hcaA)
ACI: ACIAD1726(hcaA)
CSA: Csal_0278
HAM: HALO0103
SALN: SALB1_1097
RSO: RSp0225(fca)
RSN: RSPO_m00213(fca)
RSE: F504_3664
BMA: BMAA0629
BMAL: DM55_4800
BMAE: DM78_3189
BMAQ: DM76_3754
BMAI: DM57_12400
BMAF: DM51_4342
BMAZ: BM44_4790
BMAB: BM45_4942
BPS: BPSS0779
BPM: BURPS1710b_A2361(ech)
BPSE: BDL_4061
BPSM: BBQ_5363
BPSU: BBN_4233
BPSD: BBX_5899
BPSH: DR55_4562
BPSA: BBU_5259
BVE: AK36_4870
BCN: Bcen_5223
BCJ: BCAM2793
BCEN: DM39_5052
BCEW: DM40_3360
BCEO: I35_6672
BAM: Bamb_4916
BMU: Bmul_3210
BMK: DM80_4590
BMUL: NP80_3343
BCT: GEM_5614
BCED: DM42_5195
BDL: AK34_5013
BCON: NL30_17810
BUB: BW23_3981
BLAT: WK25_29380
BTEI: WS51_10605
BSEM: WJ12_33825
BPSL: WS57_00300
BMEC: WJ16_32335
BSTG: WT74_32690
BGO: BM43_7003
BUK: MYA_3497
BUL: BW21_6349
PPNO: DA70_11115
PPNM: LV28_19940
PPUL: RO07_14150
PSPU: NA29_22960
PAPI: SG18_13975
AFQ: AFA_15960
DAC: Daci_2758
MLO: mlr1841
AVI: Avi_1705(fadB)
RLE: pRL120505(ech)
RLG: Rleg_4811
MET: M446_3478
META: Y590_19210
CCR: CC_2401
CAK: Caul_1132
CSE: Cseg_2345
NAR: Saro_1669
SPHI: TS85_18585
SSAN: NX02_02990
SJP: SJA_C1-02370(menB)
SSY: SLG_07870(ferB2) SLG_25030(ferB)
SPHR: BSY17_3548
BLAS: BSY18_3470
AAY: WYH_03221
AZL: AZL_b03680(paaG)
SEN: SACE_2794
PSEE: FRP1_10310
AMI: Amir_4116
KAL: KALB_2035
SUS: Acid_0255
 » show all
Taxonomy
Reference
1  [PMID:9611814]
  Authors
Narbad A, Gasson MJ.
  Title
Metabolism of ferulic acid via vanillin using a novel CoA-dependent pathway in a newly-isolated strain of Pseudomonas fluorescens.
  Journal
Microbiology 144 ( Pt 5):1397-405 (1998)
DOI:10.1099/00221287-144-5-1397
Reference
2  [PMID:6870241]
  Authors
Pometto AL 3rd, Crawford DL.
  Title
Whole-cell bioconversion of vanillin to vanillic acid by Streptomyces viridosporus.
  Journal
Appl Environ Microbiol 45:1582-5 (1983)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.101
IUBMB Enzyme Nomenclature: 4.2.1.101
ExPASy - ENZYME nomenclature database: 4.2.1.101
BRENDA, the Enzyme Database: 4.2.1.101
CAS: 197462-62-7

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