KEGG   ENZYME: 4.2.1.131Help
Entry
EC 4.2.1.131                Enzyme                                 

Name
carotenoid 1,2-hydratase;
CrtC
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
lycopene hydro-lyase (1-hydroxy-1,2-dihydrolycopene-forming)
Reaction(IUBMB)
(1) 1-hydroxy-1,2-dihydrolycopene = lycopene + H2O [RN:R07519];
(2) 1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene = 1-hydroxy-1,2-dihydrolycopene + H2O [RN:R09790]
Reaction(KEGG)
Substrate
1-hydroxy-1,2-dihydrolycopene [CPD:C19795];
1,1'-dihydroxy-1,1',2,2'-tetrahydrolycopene [CPD:C19894]
Product
lycopene [CPD:C05432];
H2O [CPD:C00001];
1-hydroxy-1,2-dihydrolycopene [CPD:C19795]
Comment
In Rubrivivax gelatinosus [1] and Thiocapsa roseopersicina [2] both products are formed, whereas Rhodobacter capsulatus [1] only gives 1-hydroxy-1,2-dihydrolycopene. Also acts on neurosporene giving 1-hydroxy-1,2-dihydroneurosporene with both organism but 1,1'-dihydroxy-1,1',2,2'-tetrahydroneurosporene only with Rubrivivax gelatinosus.
History
EC 4.2.1.131 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K09844  carotenoid 1,2-hydratase
Genes
ALV: Alvin_2567
TVI: Thivi_2016
TMB: Thimo_3010
MPUR: MARPU_13285
TSY: THSYN_31075
HHA: Hhal_1615
HHC: M911_10375
EBS: ECTOBSL9_3051
PDQ: CL55_00013480
RAC: RA876_06055
LIM: L103DPR2_00984(crtC)
LIH: L63ED372_00639(crtC)
RGE: RGE_33580(crtC)
MXA: MXAN_0898
CCX: COCOR_00783(crtC)
SCL: sce0584(crtC)
BRA: BRADO1613(crtC)
BBT: BBta_6442(crtC)
BRS: S23_19130(crtC)
AOL: S58_59230
BRO: BRAD285_5787(crtC)
RPA: RPA1517(crtC)
RPB: RPB_4006
RPC: RPC_1288
RPD: RPD_3761
RPE: RPE_1320
RPT: Rpal_1705
MEX: Mext_2725
MDI: METDI3491(crtC)
MCH: Mchl_2952
MPO: Mpop_2847
MET: M446_3692
MOR: MOC_3188
META: Y590_13115
MSL: Msil_2047
RVA: Rvan_0206
RSP: RSP_0267(crtC)
RCP: RCAP_rcc00682(crtC)
JAN: Jann_0184(crtC)
RDE: RD1_0116(crtC)
RLI: RLO149_p940110(crtC)
DSH: Dshi_3512(crtC)
PTP: RCA23_c29570(crtC)
RSU: NHU_04282
RHC: RGUI_1966
RMM: ROSMUCSMR3_00910(crtC)
LVS: LOKVESSMR4R_03674(crtC)
SPHI: TS85_22885
SSAN: NX02_18470
BLAS: BSY18_2719
AMV: ACMV_18840(crtC)
RRU: Rru_A2985
RRF: F11_15290
RPM: RSPPHO_02322(crtC)
IPA: Isop_1565
CTE: CT0301(crtC)
CPC: Cpar_1736
CCH: Cag_0393
CLI: Clim_0360
PVI: Cvib_1502
PLT: Plut_1720
PPH: Ppha_0465
PAA: Paes_1781
CTS: Ctha_1182
 » show all
Taxonomy
Reference
1  [PMID:12745254]
  Authors
Steiger S, Mazet A, Sandmann G
  Title
Heterologous expression, purification, and enzymatic characterization of the acyclic carotenoid 1,2-hydratase from Rubrivivax gelatinosus.
  Journal
Arch Biochem Biophys 414:51-8 (2003)
DOI:10.1016/S0003-9861(03)00099-7
  Sequence
Reference
2  [PMID:21590288]
  Authors
Hiseni A, Arends IW, Otten LG
  Title
Biochemical characterization of the carotenoid 1,2-hydratases (CrtC) from Rubrivivax gelatinosus and Thiocapsa roseopersicina.
  Journal
Appl Microbiol Biotechnol 91:1029-36 (2011)
DOI:10.1007/s00253-011-3324-1
  Sequence
[rge:RGE_33580] [ag:AAP59035]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.131
IUBMB Enzyme Nomenclature: 4.2.1.131
ExPASy - ENZYME nomenclature database: 4.2.1.131
BRENDA, the Enzyme Database: 4.2.1.131

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