KEGG   ENZYME: 4.2.1.34Help
Entry
EC 4.2.1.34                 Enzyme                                 

Name
(S)-2-methylmalate dehydratase;
mesaconate hydratase;
(+)-citramalate hydro-lyase;
L-citramalate hydrolase;
citramalate dehydratase;
(+)-citramalic hydro-lyase;
mesaconate mesaconase;
mesaconase;
(S)-2-methylmalate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
(S)-2-methylmalate hydro-lyase (2-methylfumarate-forming)
Reaction(IUBMB)
(S)-2-methylmalate = 2-methylfumarate + H2O [RN:R03693]
Reaction(KEGG)
Substrate
(S)-2-methylmalate [CPD:C02614]
Product
2-methylfumarate [CPD:C01732];
H2O [CPD:C00001]
Comment
Also hydrates fumarate to (S)-malate.
History
EC 4.2.1.34 created 1972
Pathway
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:5903732]
  Authors
Blair AH, Barker HA.
  Title
Assay and purification of (+)-citramalate hydro-lyase components from Clostridium tetanomorphum.
  Journal
J Biol Chem 241:400-8 (1966)
Reference
2  [PMID:5769987]
  Authors
Wang CC, Barker HA.
  Title
Purification and properties of L-citramalate hydrolyase.
  Journal
J Biol Chem 244:2516-26 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.34
IUBMB Enzyme Nomenclature: 4.2.1.34
ExPASy - ENZYME nomenclature database: 4.2.1.34
BRENDA, the Enzyme Database: 4.2.1.34
CAS: 9027-94-5

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