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Entry
EC 4.2.1.40                 Enzyme                                 

Name
glucarate dehydratase;
D-glucarate dehydratase;
D-glucarate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
D-glucarate hydro-lyase (5-dehydro-4-deoxy-D-glucarate-forming)
Reaction(IUBMB)
D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O [RN:R02752]
Reaction(KEGG)
R02752;
(other) R08056
Show
Substrate
D-glucarate [CPD:C00818]
Product
5-dehydro-4-deoxy-D-glucarate [CPD:C00679];
H2O [CPD:C00001]
History
EC 4.2.1.40 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K01706  glucarate dehydratase
Genes
FGR: FGSG_03645
FPU: FPSE_01890
FVR: FVEG_08810
FOX: FOXG_09660
NHE: NECHADRAFT_53344
VAL: VDBG_01855
VDA: VDAG_01700
CFJ: CFIO01_06253
ELA: UCREL1_10450
PFY: PFICI_03451
ANI: AN0613.2
ECO: b2787(gudD)
ECJ: JW2758(gudD)
ECD: ECDH10B_2955(gudD)
EBW: BWG_2525(gudD)
ECOK: ECMDS42_2291(gudD)
ECE: Z4102(ygcX)
ECS: ECs3647
ETW: ECSP_3739(gudD)
EOJ: ECO26_3857(gudD)
EOI: ECO111_3512(gudD)
EOH: ECO103_3330(gudD)
ECOO: ECRM13514_3647(ygcX)
ECOH: ECRM13516_3512(ygcX)
ECG: E2348C_3054(gudD)
EOK: G2583_3439(gudD)
ESO: O3O_20075
ESM: O3M_05620
ESL: O3K_05575
ELH: ETEC_2977
EUN: UMNK88_3470(gudD)
ECC: c3350(ygcX)
ECP: ECP_2768
ECI: UTI89_C3157(gudD)
ECV: APECO1_3744(gudD)
ECY: ECSE_3045
ECR: ECIAI1_2895(gudD)
ECQ: ECED1_3240(gudD)
ECK: EC55989_3065(gudD)
ECT: ECIAI39_3209(gudD)
EOC: CE10_3211(gudD)
EUM: ECUMN_3116(gudD)
ECZ: ECS88_3055(gudD)
ELO: EC042_2985(gudD)
ESE: ECSF_2578
EBR: ECB_02632(gudD)
EBD: ECBD_0942
EKF: KO11_09025(gudD)
EAB: ECABU_c30560(gudD)
EDJ: ECDH1ME8569_2697(gudD)
ENA: ECNA114_2823(ygcX)
ELW: ECW_m2996(gudD)
ELL: WFL_14635(gudD)
ELC: i14_3076(ygcX)
ELD: i02_3076(ygcX)
ELP: P12B_c2885(gudD)
EBL: ECD_02632(gudD)
EBE: B21_02594(gudD)
ELF: LF82_0957(gudD)
ECOA: APECO78_17550(gudD)
ECOL: LY180_14160(gudD)
ECOI: ECOPMV1_03043(gudD)
ECOJ: P423_15240(gudD)
ECOS: EC958_3054(gudD)
EFE: EFER_0276(gudD)
STY: STY3098(ygcX)
STT: t2869(ygcX)
STM: STM2960(gudD)
SEO: STM14_3568(gudD)
SEY: SL1344_2941(gudD)
SEJ: STMUK_2949(gudD)
SEB: STM474_3105(gudD)
SEF: UMN798_3218(ygcX)
SETU: STU288_14980(gudD)
SETC: CFSAN001921_02270(gudD)
SENR: STMDT2_28621(ygcX)
SEND: DT104_29581(ygcX)
SENI: CY43_15445(gudD)
SEEN: SE451236_20900(gudD)
SPT: SPA2825(ygcX)
SEK: SSPA2632
SEI: SPC_3017(ygcX)
SEC: SCH_2900(gudD)
SHB: SU5_03450
SENH: CFSAN002069_17420(gudD)
SEEH: SEEH1578_00860(gudD)
SENS: Q786_14310(gudD)
SED: SeD_A3280
SEL: SPUL_2968(gudD)
SEGA: SPUCDC_2954(gudD)
SET: SEN2805(gudD)
SENA: AU38_14245(gudD)
SENO: AU37_14255(gudD)
SENV: AU39_14255(gudD)
SENQ: AU40_16035(gudD)
SENL: IY59_14850(gudD)
SENJ: CFSAN001992_18765(gudD)
SEEC: CFSAN002050_21160(gudD)
SEEB: SEEB0189_005320(gudD)
SEEP: I137_14120(gudD)
SENE: IA1_14245(gudD)
SENC: SEET0819_21665(gudD)
SBG: SBG_2576(ygcX)
SBZ: A464_2984
SBV: N643_12600(gudD)
SFL: SF2800(ygcX)
SFX: S2994(ygcX)
SFV: SFV_2670(ygcX)
SFE: SFxv_3072(gudD)
SFN: SFy_3986
SFS: SFyv_4063
SFT: NCTC1_03079(gudD)
SSN: SSON_2944(ygcX)
SBO: SBO_2668(ygcX)
SHQ: A0259_17505(gudD)
ENC: ECL_04120
ECLO: ENC_30300
EEC: EcWSU1_03594(gudD)
ENL: A3UG_18130(gudD)
ECLE: ECNIH2_18290(gudD)
ECLN: ECNIH4_04845(gudD)
ECLI: ECNIH5_17065(gudD)
ECLX: LI66_17970(gudD)
ECLY: LI62_19430(gudD)
ECLZ: LI64_16880(gudD)
EHM: AB284_07820(gudD)
ECLA: ECNIH3_17150(gudD)
ECLC: ECR091_17085(gudD)
EAU: DI57_01370(gudD)
ECAN: CWI88_04555(gudD)
ECLS: LI67_019140(gudD)
ENR: H650_19975(gudD)
ENX: NI40_017735(gudD)
KPN: KPN_03130(gudD)
KPU: KP1_4402(gudD)
KPP: A79E_0967
KPK: A593_05835(gudD)
KPH: KPNIH24_07765(gudD)
KPZ: KPNIH27_20365(gudD)
KPV: KPNIH29_21125(gudD)
KPW: KPNIH30_21145(gudD)
KPY: KPNIH31_20410(gudD)
KPG: KPNIH32_22005(gudD)
KPC: KPNIH10_20945(gudD)
KPQ: KPR0928_20430(gudD)
KPT: VK055_4384(gudD2)
KPE: KPK_0992(gudD)
KPR: KPR_4139
KPJ: N559_1100
KPI: D364_15955(gudD)
KPX: PMK1_00611(gudD)
KPB: FH42_11670(gudD)
KPNE: KU54_005425(gudD)
KPNU: LI86_05435(gudD)
KPNK: BN49_0984
KVA: Kvar_0925
KOX: KOX_01175
KOE: A225_4697
KOM: HR38_27300(gudD)
KOK: KONIH1_23595(gudD)
KOC: AB185_12785(gudD)
EAE: EAE_01985
EAR: CCG33595
KQV: B8P98_05435(gudD)
CKO: CKO_04141
CRO: ROD_30271(gudD)
CFD: CFNIH1_00870(gudD)
CBRA: A6J81_22135(gudD)
CWE: CO701_03470(gudD)
CYO: CD187_04935(gudD)
CAMA: F384_15105(gudD)
CAF: AL524_07860(gudD)
CIF: AL515_18520(gudD)
CFAR: CI104_20070(gudD)
CIR: C2U53_14870(gudD)
CIE: AN232_09490(gudD)
EBT: EBL_c08370(gudD)
ROR: RORB6_23640(gudD)
RON: TE10_22600(gudD)
RAO: DSD31_05125(gudD)
KOR: AWR26_20365(gudD)
KRD: A3780_03375(gudD)
KIN: AB182_04095(gudD) AB182_04480(gudD)
LAX: APT61_04600(gudD)
LEI: C2U54_23490(gudD)
LEH: C3F35_16405(gudD)
LNI: CWR52_17125(gudD)
LEW: DAI21_09350(gudD)
LPV: HYN51_05380(gudD)
EBF: D782_0928
EBC: C2U52_13870(gudD) C2U52_14295(gudD)
SRL: SOD_c06600(gudD)
SRY: M621_03460(gudD)
SPLY: Q5A_003460(gudD)
SMAF: D781_0747
SFW: WN53_12365(gudD)
SFG: AV650_07890(gudD)
SERA: Ser39006_007225(gudD)
SERM: CLM71_03630(gudD)
SFO: Z042_16585(gudD)
RAA: Q7S_18335
ECA: ECA3575(gudD)
PATR: EV46_17740(gudD)
PATO: GZ59_35990(gudD)
PCT: PC1_3395
PCV: BCS7_17105(gudD)
PEC: W5S_3692
SGL: SG0506
SOD: Sant_3274(ygcX)
DDD: Dda3937_00189(gudD)
DZC: W909_16010(gudD)
DSO: A4U42_04595(gudD)
CED: LH89_17040(gudD)
DDQ: DDI_3297
DFN: CVE23_17785(gudD)
BGJ: AWC36_05970(gudD)
EBI: EbC_35530(ygcX)
EGE: EM595_2827(ygcX)
PAM: PANA_3084(gudD)
PLF: PANA5342_0949(gudD)
PAJ: PAJ_2358(gudD)
PVA: Pvag_2467(ygcX)
PAGG: AL522_19440(gudD)
KLN: LH22_06890(gudD)
PANT: PSNIH1_02105(gudD)
PANP: PSNIH2_02325(gudD)
PGZ: C2E15_16875(gudD)
PCD: C2E16_16745(gudD)
PFQ: QQ39_04690(gudD)
LRI: NCTC12151_02557(gudD)
MSU: MS0689(dgoA)
ASU: Asuc_1847
XCC: XCC3242(tcbD)
XCB: XC_0951
XCA: xcc-b100_0943(gudD)
XCP: XCR_3582
XFU: XFF4834R_chr12560(gudD)
PRE: PCA10_06320(gudD) PCA10_06340(gudD)
PPSE: BN5_3137(gudD3) BN5_3138(gudD)
PPU: PP_4757(gudD)
PPF: Pput_4631
PPT: PPS_4594
PPI: YSA_03618
PPX: T1E_0686(gdh)
PPUH: B479_23220(gudD)
PPUT: L483_28890(gudD)
PPUN: PP4_47390(gudD)
PPUD: DW66_4984
PMON: X969_22650(gudD)
PMOT: X970_22285(gudD)
PMOS: O165_027095(gudD)
PSYR: N018_13690 N018_15695(gudD)
PFC: PflA506_3565(gudD)
PFF: PFLUOLIPICF717455(gudD)
PMAN: OU5_1305
PAZO: AYR47_27960(gudD)
PEN: PSEEN0731(gudD)
PSC: A458_01950(gudD) A458_01965(gudD)
PSJ: PSJM300_10065(gudD) PSJM300_10080(gudD)
PSTT: CH92_11145 CH92_11160(gudD)
PPUU: PputUW4_01637(gudD)
PSV: PVLB_03330(gudD)
PSK: U771_13420(gudD)
PCH: EY04_20145(gudD)
PCP: JM49_11045(gudD)
PSEM: TO66_20815(gudD)
PPSY: AOC04_10775(gudD)
PANR: A7J50_3922
PSIL: PMA3_16960 PMA3_18015(gudD)
ACX: Achr_16400(gudD)
ACB: A1S_1100
ABM: ABSDF1407(gudD)
ABN: AB57_1183
ABB: ABBFA_002445(gudD)
ABAZ: P795_11825
ABK: LX00_05590(gudD)
ABAA: IX88_07750(gudD)
ACC: BDGL_000380(gudD)
ACI: ACIAD0128(gudD)
HEL: HELO_3412(gudD)
HAM: HALO3648
HHU: AR456_05295(gudD)
HCO: LOKO_00794(gudD)
HALO: BWR19_13185(gudD)
HAA: A5892_03115(gudD)
KUS: B9G99_15885(gudD)
KMA: B9H00_15750(gudD)
MARS: A8C75_18995(gudD)
TAU: Tola_2582
RSO: RSc1079(gudD1) RSp0829(gudD2)
RSC: RCFBP_20395(gudD)
RSL: RPSI07_2312(gudD) RPSI07_mp0773(gudD)
RSN: RSPO_c02285(gudD) RSPO_m01147(gudD2)
RSM: CMR15_20198(gudD) CMR15_mp10805(gudD)
RPJ: N234_21605(gudD)
REH: H16_B0127(h16_B0127)
CNC: CNE_2c01110(gudD)
RME: Rmet_0834(gudD)
CTI: RALTA_B0133(gudD)
CGD: CR3_0771(gudD)
BTE: BTH_I0189
BTQ: BTQ_213 BTQ_214(gudD)
BTJ: BTJ_2271(gudD) BTJ_2272
BTZ: BTL_186(gudD) BTL_187
BTD: BTI_3531(gudD) BTI_3532(gudD)
BTV: BTHA_243(gudD) BTHA_244
BTHE: BTN_1205 BTN_1206(gudD)
BTHM: BTRA_387(gudD) BTRA_388
BTHA: DR62_1380 DR62_1381(gudD)
BTHL: BG87_350(gudD) BG87_351
BOK: DM82_3412(gudD) DM82_3413(gudD)
BOC: BG90_1405(gudD) BG90_1406
BVE: AK36_2765(gudD) AK36_546
BCJ: BCAL0183(gudD) BCAL1043(gudD)
BCEN: DM39_1009(gudD) DM39_103
BCEW: DM40_1010 DM40_1828(gudD)
BCEO: I35_0172(gudD) I35_1034(gudD)
BMJ: BMULJ_01103(gudD) BMULJ_03062(gudD)
BMK: DM80_1387 DM80_474(gudD)
BMUL: NP80_1269(gudD) NP80_334
BCED: DM42_1534 DM42_559(gudD)
BDL: AK34_1991(gudD) AK34_2858
BCON: NL30_09820(gudD) NL30_18375
BUB: BW23_1463 BW23_567(gudD)
BLAT: WK25_01250 WK25_05545(gudD)
BTEI: WS51_11870 WS51_16085(gudD)
BSEM: WJ12_01130 WJ12_05710(gudD)
BPSL: WS57_14005 WS57_23400(gudD)
BMEC: WJ16_01075 WJ16_05485(gudD)
BSTG: WT74_01430 WT74_05835(gudD)
BGU: KS03_3623(gudD)
BGO: BM43_2842 BM43_6746(gudD)
BUL: BW21_17(gudD) BW21_18
BUZ: AYM40_22735(gudD)
BUM: AXG89_18660(gudD)
BXE: Bxe_B0539
BXB: DR64_5870(gudD)
BPH: Bphy_6530
BFN: OI25_6253(gudD)
PARB: CJU94_26815(gudD)
PHS: C2L64_37945(gudD)
PTER: C2L65_33890(gudD)
PPNO: DA70_01795(gudD) DA70_20700
PPNM: LV28_04550(gudD) LV28_09675
PAPI: SG18_04060 SG18_22925(gudD)
PLG: NCTC10937_02275(gudD_1) NCTC10937_04452(gudD_2)
PUT: PT7_0673
AMIM: MIM_c31790
ODI: ODI_R1360
POL: Bpro_3421
PNA: Pnap_1130
AAV: Aave_3623
AAA: Acav_3539
ACK: C380_15200(gudD)
ACRA: BSY15_136(gudD)
VPD: VAPA_1c18200(gudD)
VAA: AX767_10460(gudD)
VAM: C4F17_00105(gudD)
CTES: O987_01220 O987_01255(gudD)
RTA: Rta_19130(gudD)
LIM: L103DPR2_02531(gudD)
LIH: L63ED372_02035(gudD_1) L63ED372_02041(gudD_2)
HYB: Q5W_05580
MPT: Mpe_A0970
HRB: Hrubri_0965(gudD)
CFU: CFU_0746(ygcX)
CARE: LT85_0825
CPRA: CPter91_0867(gudD)
MASW: AM586_16630(gudD) AM586_23235(gudD)
LCH: Lcho_1118
MIU: ABE85_15685(gudD)
PBH: AAW51_4402(gudD)
THU: AC731_014325(gudD)
SCL: sce5159(gudD)
MLO: mll7352
SMER: DU99_25330
SMD: Smed_5845
ATU: Atu3029(gudD)
ATF: Ach5_28190(gudD)
RIR: BN877_II0934(gudD)
SHZ: shn_24480
BJA: blr5872(gudD)
BJP: RN69_18605(gudD)
BRA: BRADO1564(gudD)
BBT: BBta_6488(gudD)
BRS: S23_23770(gudD)
AOL: S58_17930
BRC: BCCGELA001_25015(gudD)
BRAD: BF49_5763
BRO: BRAD285_5836(gudD)
BRK: CWS35_13630(gudD)
BOT: CIT37_24935(gudD)
MET: M446_6204
MNO: Mnod_7096
MOR: MOC_5862(gudD)
OTM: OSB_21160(gudD)
AHT: ANTHELSMS3_01908(gudD)
SMAZ: LH19_24825
SYA: A6768_06985(gudD)
AZL: AZL_a04700(gudD)
BSU: BSU02490(gudD)
BSR: I33_0289
BSL: A7A1_1951
BSH: BSU6051_02490(gudD)
BSY: I653_01215(gudD)
BSUT: BSUB_00297(gudD)
BSUL: BSUA_00297(gudD)
BSUS: Q433_01515(gudD)
BSS: BSUW23_01275(gudD)
BST: GYO_0448(gudD)
BSO: BSNT_06560(ycbF)
BSQ: B657_02490(gudD)
BSX: C663_0238
BLI: BL01649(gudD)
BLD: BLi00287(gudD)
BLH: BaLi_c03050(gudD)
BATR: TD68_18905(gudD)
BMQ: BMQ_1893(gudD)
BJS: MY9_0250
BACY: QF06_00200(gudD)
BACL: BS34A_03030(gudD)
BALM: BsLM_0255
BEO: BEH_09690
BSJ: UP17_19535(gudD)
BGY: BGLY_0291(gudD)
BKO: CKF48_05595(gudD)
BSAF: BSL056_04735(gudD)
BIT: BIS30_11785(gudD)
OIH: OB2836
GGH: GHH_c13980(gudD)
TAP: GZ22_13860(gudD)
PMS: KNP414_04897(gudD)
LBN: LBUCD034_0064(gudD1) LBUCD034_0065(gudD2)
LALI: LA20249_09325(gudD)
THL: TEH_05290(gudD)
CACE: CACET_c11400(gudD1) CACET_c11450(gudD2)
FPLA: A4U99_15310(gudD)
RTO: RTO_06330
AIN: Acin_1572(gudD)
CAMG: CAMM_01100(gudD)
NFA: NFA_35070
NFR: ERS450000_00543(gudD)
ROP: ROP_36490 ROP_38040(gudD)
RFA: A3L23_01459(gudD_1) A3L23_01462(gudD_2)
RHS: A3Q41_01895(gudD_1) A3Q41_01898(gudD_2)
SCO: SCO2542(SCC77.09c) SCO7570(SC5F1.24)
SMA: SAVERM_5581(gudD)
SGR: SGR_5812
SGB: WQO_06230
SCT: SCAT_0892(gudD)
SFA: Sfla_1412
SHY: SHJG_4033
SDV: BN159_5755(gudD)
SALS: SLNWT_3894
STRP: F750_5469
SFI: SFUL_1212
SALU: DC74_3074
SALL: SAZ_16405
SGU: SGLAU_02330(gudD)
STRE: GZL_05860
SAMB: SAM23877_0538(gudD)
SPRI: SPRI_4915
SRW: TUE45_03140(gudD)
SLE: sle_06450(sle_06450) sle_46900(sle_46900)
SCLF: BB341_29820(gudD)
SNR: SNOUR_27580(gudD)
STRD: NI25_26330
SALF: SMD44_00730(gudD)
SFK: KY5_2660c
CMI: CMM_2413
CMS: CMS2354(gudD)
ARQ: BWQ92_10200(gudD)
BCV: Bcav_2699
IDO: I598_2354(gudD)
KFL: Kfla_4968
NDA: Ndas_2497
GOB: Gobs_2393
AMD: AMED_5973(gudD)
AMN: RAM_30635
AMM: AMES_5889(gudD)
AMZ: B737_5889(gudD)
AOI: AORI_5000(gudD)
AJA: AJAP_14520(gudD)
AMI: Amir_1488
KAL: KALB_6870
AHG: AHOG_20630(gudD)
PMAD: BAY61_15105(gudD)
SAQ: Sare_3003
AFS: AFR_26115
ASG: FB03_06975(gudD)
ACTT: DDD63_00655(gudD) DDD63_00665(gudD)
BACT: AB656_00390(gudD) AB656_00395(gudD)
TBI: Tbis_1083
FHW: RN87_10285(gudD)
FVA: FV113G1_05540(gudD) FV113G1_17730(gudD)
GBA: J421_1905
DFE: Dfer_1407
SLI: Slin_1068
SID: M164_2336
 » show all
Taxonomy
Reference
1
  Authors
Blumenthal, H.J.
  Title
D-Glucarate dehydrase.
  Journal
Methods Enzymol 9:660-665 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.40
IUBMB Enzyme Nomenclature: 4.2.1.40
ExPASy - ENZYME nomenclature database: 4.2.1.40
BRENDA, the Enzyme Database: 4.2.1.40
CAS: 9059-02-3

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