KEGG   ENZYME: 4.2.1.41Help
Entry
EC 4.2.1.41                 Enzyme                                 

Name
5-dehydro-4-deoxyglucarate dehydratase;
5-keto-4-deoxy-glucarate dehydratase;
5-keto-4-deoxy-glucarate dehydratase;
deoxyketoglucarate dehydratase;
D-4-deoxy-5-ketoglucarate hydro-lyase;
5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
5-dehydro-4-deoxy-D-glucarate hydro-lyase (decarboxylating; 2,5-dioxopentanoate-forming)
Reaction(IUBMB)
5-dehydro-4-deoxy-D-glucarate = 2,5-dioxopentanoate + H2O + CO2 [RN:R02279]
Reaction(KEGG)
Substrate
5-dehydro-4-deoxy-D-glucarate [CPD:C00679]
Product
2,5-dioxopentanoate [CPD:C00433];
H2O [CPD:C00001];
CO2 [CPD:C00011]
History
EC 4.2.1.41 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K01707  5-dehydro-4-deoxyglucarate dehydratase
Genes
XCC: XCC3245(dapA)
XCB: XC_0954
XCA: xcc-b100_0940(kdgD)
XCP: XCR_3585
XFU: XFF4834R_chr12530
XVE: BJD12_07655
FAU: Fraau_1630
PMY: Pmen_1215
PMK: MDS_1252
PRE: PCA10_06300
PPU: PP_3599(kdgD)
PPF: Pput_3098
PPT: PPS_3092
PPI: YSA_09616
PPX: T1E_0930
PPUH: B479_15380
PPUT: L483_18860
PPUN: PP4_22280
PPUD: DW66_3364
PMON: X969_14860
PMOT: X970_14505
PSB: Psyr_4227
PSYR: N018_04050
PAMG: BKM19_024955(kdgD)
PAVL: BKM03_24685(kdgD)
PFC: PflA506_0839(kdgD)
PFB: VO64_3933
PMAN: OU5_2579
PEN: PSEEN2658(kdgD)
PSTT: CH92_11150
PPUU: PputUW4_00752(kdgD)
PSES: PSCI_2636
PSEM: TO66_04555
PANR: A7J50_0856
PSIL: PMA3_25240
ACB: A1S_1101
ABM: ABSDF1408(kdgD)
ABN: AB57_1185
ABB: ABBFA_002443(kdgD)
ABAZ: P795_11820
ABAU: IX87_05340
ABAA: IX88_07755
ACI: ACIAD0130(kdgD)
CSA: Csal_2487
HEL: HELO_3417
HAM: HALO3647
SALN: SALB1_0471
RSO: RSp0826
RSL: RPSI07_mp0770(kdgD)
RSN: RSPO_m01144(kdgD)
RSM: CMR15_mp10802(kdgD)
RSE: F504_4393
RPI: Rpic_4452
RIN: ACS15_4457(kdgD)
REH: H16_B0131(h16_B0131)
RME: Rmet_4736(kdgD)
CGD: CR3_0769
BUT: X994_6518(kdgD)
BTE: BTH_I0185
BTQ: BTQ_210(kdgD)
BTJ: BTJ_2275(kdgD)
BTZ: BTL_190(kdgD)
BTD: BTI_3535(kdgD)
BTV: BTHA_247(kdgD)
BTHE: BTN_1202(kdgD)
BTHM: BTRA_391(kdgD)
BTHA: DR62_1377
BTHL: BG87_354(kdgD)
BOK: DM82_3409(kdgD)
BOC: BG90_1409(kdgD)
BVE: AK36_3198(kdgD)
BCN: Bcen_3049
BCJ: BCAM2512
BCEN: DM39_5322(kdgD)
BCEW: DM40_3164(kdgD)
BCEO: I35_6412
BAM: Bamb_4676
BMU: Bmul_3408
BMK: DM80_4792(kdgD)
BMUL: NP80_5141(kdgD)
BCT: GEM_5882
BCED: DM42_5462(kdgD)
BDL: AK34_3312(kdgD)
BCON: NL30_16395
BUB: BW23_3745(kdgD)
BLAT: WK25_28415
BTEI: WS51_09515
BSEM: WJ12_32620
BPSL: WS57_01555
BMEC: WJ16_31095
BSTG: WT74_31440
BGU: KS03_3622(kdgD) KS03_5548(kdgD)
BGO: BM43_4174(kdgD) BM43_6747(kdgD)
BUK: MYA_3190
BUL: BW21_21(kdgD)
BXE: Bxe_B1802
BXB: DR64_7108(kdgD)
BPH: Bphy_6531
BFN: OI25_4247(kdgD) OI25_6254(kdgD)
PARB: CJU94_20730(kdgD)
PHS: C2L64_07740(kdgD) C2L64_37940(kdgD)
PTER: C2L65_07480(kdgD) C2L65_33885(kdgD)
PGP: CUJ91_25815(kdgD) CUJ91_28950(kdgD)
PPNO: DA70_20745
PPNM: LV28_09630
PPUL: RO07_03805
PSPU: NA29_24795
PAPI: SG18_03985
PLG: NCTC10937_04575(mosA)
BPT: Bpet3876(kdgD)
AXY: AXYL_03082(kdgD)
AXX: ERS451415_02952(mosA)
ASW: CVS48_18085(kdgD)
ODI: ODI_R4401
POL: Bpro_3419
PNA: Pnap_1596
AAV: Aave_2587
AJS: Ajs_1993
AAA: Acav_2616
ACRA: BSY15_139(kdgD)
DAC: Daci_0251
VPD: VAPA_1c18170(kdgD)
VBO: CKY39_11835(kdgD)
VAM: C4F17_00100(kdgD)
CTES: O987_01235
RTA: Rta_19100
HYR: BSY239_3016(kdgD)
HEE: hmeg3_12170(kdgD) hmeg3_15575(kdgD)
CFU: CFU_0234(kdgD)
CARE: LT85_0228
MASS: CR152_10405(kdgD)
MASZ: C9I28_04725(kdgD)
MTIM: DIR46_25295(kdgD)
MASY: DPH57_17225(kdgD)
LCH: Lcho_1117
PBH: AAW51_4401(kdgD)
MES: Meso_1947
SME: SMa1440
SMD: Smed_5081
SFH: SFHH103_06370(kdgD)
ATU: Atu3140
ARA: Arad_9704
ATF: Ach5_29950(kdgD)
AVI: Avi_5701
AGC: BSY240_2210(kdgD)
ARO: B0909_22895(kdgD)
RIR: BN877_II0124(kdgD)
RHL: LPU83_pLPU83c0513(kdgD)
OCH: CES85_3618(kdgD)
BJA: blr5871
BRA: BRADO1565(kdgD)
BBT: BBta_6487(kdgD)
BRS: S23_23780
AOL: S58_17940
BRAD: BF49_5764
BRO: BRAD285_5835(kdgD)
BRK: CWS35_13635(kdgD)
BOT: CIT37_24940(kdgD)
BOS: BSY19_2089(kdgD)
XAU: Xaut_3371
AZC: AZC_2638
MOR: MOC_5860(kdgD)
MEE: DA075_21850(kdgD)
PHL: KKY_3041
MMED: Mame_05254(dapA_7)
BRN: D1F64_18260(kdgD)
HDI: HDIA_P0037(dapA_3)
RSP: RSP_3655
PZH: CX676_05250(kdgD)
CID: P73_1651
YPAC: CEW88_05330(kdgD)
HBA: Hbal_2503
NOV: TQ38_024235(kdgD)
SSAN: NX02_20065
SPHC: CVN68_20440(kdgD)
SYA: A6768_00810(kdgD) A6768_06970(kdgD)
ROS: CTJ15_16185(kdgD)
TXI: TH3_13605
THAC: CSC3H3_18915(kdgD) CSC3H3_22110(kdgD)
TII: DY252_16320(kdgD)
BSU: BSU02460(ycbC)
BSR: I33_0286(kdgD)
BSL: A7A1_3235
BSH: BSU6051_02460(ycbC)
BSUT: BSUB_00294(ycbC)
BSUL: BSUA_00294(ycbC)
BSUS: Q433_01500
BSS: BSUW23_01260(ycbC)
BST: GYO_0445(kdgD)
BSO: BSNT_06556(ycbC)
BSQ: B657_02460(ycbC)
BSX: C663_0235(ycbC)
BLI: BL01645(kdgD)
BLD: BLi00284(ycbC)
BLH: BaLi_c03020(ycbC)
BATR: TD68_18890
BCL: ABC0471
BMQ: BMQ_1890(ycbC)
BACY: QF06_00185
BACL: BS34A_03000(ycbC)
BALM: BsLM_0252
BEO: BEH_09675
BGY: BGLY_0288
BKO: CKF48_05610(kdgD)
OIH: OB2841
GGH: GHH_c14000(ycbC)
VNE: CFK40_15180(kdgD)
MVA: Mvan_1030
CGL: NCgl0438(Cgl0453)
CGB: cg0536
CGU: WA5_0438
CGT: cgR_0526
CGM: cgp_0536
CGJ: AR0_02815
CAMG: CAMM_01110
NFA: NFA_35040
NFR: ERS450000_00546(mosA_1)
NTP: CRH09_35405(kdgD)
RHB: NY08_3286
GBR: Gbro_4201
GOR: KTR9_2910
SCO: SCO1895(SCI7.13c) SCO2543(SCC77.10c)
SGR: SGR_5617
SGB: WQO_07260
SCT: SCAT_1074
SFA: Sfla_4919
SBH: SBI_08102(dapA1) SBI_09218(dapA2)
SALS: SLNWT_3893
STRP: F750_1763
SFI: SFUL_1460
SALU: DC74_2380
SALL: SAZ_13255
STRE: GZL_06627
SPRI: SPRI_5629
SLE: sle_06490(sle_06490) sle_52390(sle_52390)
STRD: NI25_29725
SFK: KY5_1805c
CMI: CMM_2414
CMS: CMS2355
AAU: AAur_3319
BCV: Bcav_0788
IDO: I598_2356
TFU: Tfu_1718
SRO: Sros_1498
GOB: Gobs_2392
BSD: BLASA_1679(kdgD)
SEN: SACE_0344(dapA) SACE_1971
AMD: AMED_5974
AMN: RAM_30640
AMM: AMES_5890
AMZ: B737_5890
AOI: AORI_5001
PSEE: FRP1_25200
AMI: Amir_1487
KAL: KALB_6871
SNA: Snas_0755
TBI: Tbis_1084
 » show all
Taxonomy
Reference
1  [PMID:4982840]
  Authors
Jeffcoat R, Hassall H, Dagley S.
  Title
Purification and properties of D-4-deoxy-5-oxoglucarate hydro-lyase (decarboxylating).
  Journal
Biochem J 115:977-83 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.41
IUBMB Enzyme Nomenclature: 4.2.1.41
ExPASy - ENZYME nomenclature database: 4.2.1.41
BRENDA, the Enzyme Database: 4.2.1.41
CAS: 37290-77-0

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