KEGG   ENZYME: 4.2.1.43Help
Entry
EC 4.2.1.43                 Enzyme                                 

Name
2-dehydro-3-deoxy-L-arabinonate dehydratase;
2-keto-3-deoxy-L-arabinonate dehydratase;
2-dehydro-3-deoxy-L-arabinonate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
2-dehydro-3-deoxy-L-arabinonate hydro-lyase (2,5-dioxopentanoate-forming)
Reaction(IUBMB)
2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H2O [RN:R02278]
Reaction(KEGG)
Substrate
2-dehydro-3-deoxy-L-arabinonate [CPD:C00684]
Product
2,5-dioxopentanoate [CPD:C00433];
H2O [CPD:C00001]
History
EC 4.2.1.43 created 1972
Pathway
ec00053  Ascorbate and aldarate metabolism
ec01100  Metabolic pathways
Orthology
K13876  2-keto-3-deoxy-L-arabinonate dehydratase
Genes
CAF: AL524_22380
KCO: BWI95_18060
SOD: Sant_0675
EPE: CI789_02275
RFO: REIFOR_01233
RPI: Rpic_3006
RPF: Rpic12D_2596
RPJ: N234_21925
RMN: TK49_06590
REH: H16_B0213(dapA2)
CNC: CNE_2c01980(dapA1)
CGD: CR3_3974(araD)
BTQ: BTQ_4919(araD)
BTJ: BTJ_3543(araD)
BTZ: BTL_4392(araD)
BTD: BTI_5591(araD)
BTV: BTHA_3565(araD)
BTHE: BTN_4043(araD)
BTHM: BTRA_4050(araD)
BTHA: DR62_4079
BTHL: BG87_4375(AraD)
BVE: AK36_4877(araD)
BCN: Bcen_5216
BCJ: BCAM2800
BCEN: DM39_5046(araD) DM39_6177(araD)
BCEW: DM40_3367(araD)
BCEO: I35_6679
BMU: Bmul_3204
BMJ: BMULJ_05321(dapA)
BMK: DM80_4584(araD)
BMUL: NP80_3349(araD)
BCED: DM42_5188(araD)
BDL: AK34_5007(araD)
BUB: BW23_3987(araD) BW23_4351(araD)
BLAT: WK25_29415
BTEI: WS51_10640
BGU: KS03_2640(araD)
BGO: BM43_5015(araD)
BUK: MYA_3489
BUL: BW21_5279(araD)
BPH: Bphy_6711
BHO: D560_1639
BHM: D558_1627
AXX: ERS451415_04605(yagE_2)
ODI: ODI_R4258
RFR: Rfer_0453
POL: Bpro_2837
AAV: Aave_2247
AAA: Acav_2893
VEI: Veis_2707
DAC: Daci_4983
CTES: O987_23535
HSE: Hsero_1368(dapA)
HRB: Hrubri_1189(dapA)
MES: Meso_3971
BJA: bll7953
BRA: BRADO1813
BBT: BBta_2133
BRS: S23_65840
AOL: S58_57230
BRAD: BF49_3436
BRO: BRAD285_5472(araD)
XAU: Xaut_1021
SNO: Snov_0118
MOR: MOC_5613
MAQU: Maq22A_c05765(dapA)
BID: Bind_3080
HDI: HDIA_0216(araD)
SIL: SPOA0244
PDE: Pden_4666
DSH: Dshi_2446
RHC: RGUI_3959
LVS: LOKVESSMR4R_03077(araD)
ACR: Acry_2738
AZL: AZL_e03630(dapA)
ALI: AZOLI_p50377(araD)
ACTI: UA75_20040
ACAD: UA74_19550
ABAC: LuPra_02639(araD_1)
 » show all
Taxonomy
Reference
1  [PMID:5954356]
  Authors
Stoolmiller AC, Abeles RH.
  Title
Formation of alpha-ketoglutaric semialdehyde from L-2-keto-3-deoxyarabonic acid and isolation of L-2-keto-3-deoxyarabonate dehydratase from Pseudomonas saccharophila.
  Journal
J Biol Chem 241:5764-71 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.43
IUBMB Enzyme Nomenclature: 4.2.1.43
ExPASy - ENZYME nomenclature database: 4.2.1.43
BRENDA, the Enzyme Database: 4.2.1.43
CAS: 37263-10-8

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