KEGG   ENZYME: 4.2.1.48Help
Entry
EC 4.2.1.48                 Enzyme                                 

Name
D-glutamate cyclase;
D-glutamate hydro-lyase (cyclizing)
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)
Reaction(IUBMB)
D-glutamate = 5-oxo-D-proline + H2O [RN:R01583]
Reaction(KEGG)
Substrate
D-glutamate [CPD:C00217]
Product
5-oxo-D-proline [CPD:C02237];
H2O [CPD:C00001]
Comment
Also acts on various derivatives of D-glutamate.
History
EC 4.2.1.48 created 1972
Pathway
ec00471  D-Glutamine and D-glutamate metabolism
Orthology
K22210  D-glutamate cyclase
Genes
HSA: 80017(DGLUCY)
PTR: 453104(DGLUCY)
PPS: 100971567(C14H14orf159)
GGO: 101153207(C14H14orf159)
PON: 100172319(DGLUCY)
NLE: 100586901(C22AH14orf159)
MCC: 700168(C7H14orf159)
MCF: 102135732(C7H14orf159)
CSAB: 103229551(C24H14orf159)
RRO: 104656701
RBB: 108523309(CUNH14orf159)
SBQ: 101047007
MMU: 217830(Dglucy)
RNO: 362769(RGD1311756)
CGE: 100753550
NGI: 103724611(CUNH14orf159)
HGL: 101711224
CCAN: 109699498(CUNH14orf159)
TUP: 102469364
CFA: 100688910(DGLUCY)
AML: 100482436(CUNH14orf159)
UMR: 103670181
ORO: 101371157
PTG: 102949759
AJU: 106987920
SSC: 100626547(C7H14orf159)
CFR: 102521322
CDK: 105095965
BACU: 102999377
LVE: 103084864
OOR: 101287758
ECB: 100063012(DGLUCY)
EPZ: 103558013
EAI: 106825335
MYB: 102252495
MYD: 102753826
HAI: 109382680(CUNH14orf159)
RSS: 109454429(CUNH14orf159)
PALE: 102898067(DGLUCY)
LAV: 100659904(DGLUCY)
MDO: 100017774(C1H14orf159)
SHR: 100931620(DGLUCY)
OAA: 100083826
GGA: 423409(C5H14orf159)
MGP: 100539918(C5H14orf159)
CJO: 107315200(C5H14orf159)
APLA: 101791243
ACYG: 106036649
TGU: 100229540(C5H14orf159)
GFR: 102037421
FAB: 101806679(C5H14orf159)
PHI: 102108442
PMAJ: 107205561(C5H14orf159)
CCW: 104685987(CUNH14orf159)
FPG: 101913280
FCH: 102058374
CLV: 102096431(CUNH14orf159)
EGZ: 104135348
AAM: 106482923
ASN: 102380281(DGLUCY)
AMJ: 102576478(CUNH14orf159)
PSS: 102453950(DGLUCY)
CMY: 102931212
CPIC: 101937326
ACS: 100562196(c1h14orf159)
PVT: 110086580(CUNH14orf159)
PBI: 103063698(DGLUCY)
GJA: 107113340
XLA: 108698713(c14orf159.L)
XTR: 549215(c14orf159)
NPR: 108788696(CUNH14orf159)
DRE: 560387(c17h14orf159)
SRX: 107730207
SANH: 107679776
SGH: 107582942
CCAR: 109107902(c34h14orf159)
AMEX: 103041880(dglucy)
TRU: 101064729
MZE: 101472904(dglucy)
OLA: 101156702(dglucy)
XMA: 102226444(dglucy)
PRET: 103460669
NFU: 107391670(csgr16h14orf159)
BPEC: 110163870 110166339(cunh14orf159)
SASA: 106611165(cssa09h14orf159)
ELS: 105015466(lg15h14orf159)
SFM: 108933257(cunh14orf159)
LCM: 102346195
CMK: 103189663
CIN: 100180171
SPU: 577417
SKO: 100368287
HMG: 100204445
SMIN: v1.2.019446.t1(symbB.v1.2.019446.t1) v1.2.019446.t2(symbB.v1.2.019446.t2)
SPAR: SPRG_00060
 » show all
Taxonomy
Reference
1  [PMID:14087295]
  Authors
MEISTER A, BUKENBERGER MW, STRASSBURGER M.
  Title
THE OPTICALLY-SPECIFIC  ENZYMATIC CYCLIZATION OF D-GLUTAMATE.
  Journal
Biochem Z 338:217-29 (1963)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.48
IUBMB Enzyme Nomenclature: 4.2.1.48
ExPASy - ENZYME nomenclature database: 4.2.1.48
BRENDA, the Enzyme Database: 4.2.1.48
CAS: 37290-80-5

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