KEGG   ENZYME: 4.2.1.55Help
Entry
EC 4.2.1.55                 Enzyme                                 

Name
3-hydroxybutyryl-CoA dehydratase;
D-3-hydroxybutyryl coenzyme A dehydratase;
D-3-hydroxybutyryl-CoA dehydratase;
enoyl coenzyme A hydrase (D);
(3R)-3-hydroxybutanoyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
(3R)-3-hydroxybutanoyl-CoA hydro-lyase (crotonoyl-CoA-forming)
Reaction(IUBMB)
(3R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H2O [RN:R03027]
Reaction(KEGG)
Substrate
(3R)-3-hydroxybutanoyl-CoA [CPD:C03561]
Product
crotonoyl-CoA [CPD:C00877];
H2O [CPD:C00001]
Comment
Also acts on crotonoyl thioesters of pantetheine and acyl-carrier protein.
History
EC 4.2.1.55 created 1972
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00650  Butanoate metabolism
ec01120  Microbial metabolism in diverse environments
Orthology
K17865  3-hydroxybutyryl-CoA dehydratase
Genes
PHD: 102324794
SMO: SELMODRAFT_270463
ENR: H650_03750
CIE: AN232_13780
KSA: C813_04365
KOR: AWR26_00185
KRD: A3780_24495
PSUW: WQ53_08610
LYT: DWG18_00380
VVL: VV93_v1c03360
ABH: M3Q_289
CYQ: Q91_1228 Q91_1346(maoC)
AEH: Mlg_2811
HHA: Hhal_1055
ADI: B5T_04119
AXE: P40_20070
CVI: CV_3819
LHK: LHK_02914
PSE: NH8B_3503
RME: Rmet_1672
BVE: AK36_5946
BAM: Bamb_6218
BCED: DM42_2061
BCON: NL30_35025
BPH: Bphy_6753
ODI: ODI_R3784
PNA: Pnap_3284
LCH: Lcho_3597
EBA: ebA4434
DSU: Dsui_1352
DAR: Daro_3467
AZO: azo3194
AZA: AZKH_1173
AOA: dqs_3327
TCL: Tchl_0770
ARC: ABLL_0105
DAT: HRM2_42120(maoC)
MES: Meso_1940
RIR: BN877_p0414(maoC)
BJA: blr3306
XAU: Xaut_2482
AZC: AZC_0033
MEX: Mext_3444
MEA: Mex_1p3675(croR)
MDI: METDI4248(croR)
MCH: Mchl_3753
MPO: Mpop_3642
MET: M446_5194
MNO: Mnod_5970
MOR: MOC_5744
META: Y590_16915
MAQU: Maq22A_c17200(croR)
HDN: Hden_2610
RVA: Rvan_1595
BVR: BVIR_2707
MSC: BN69_2149
MCG: GL4_0954
HDI: HDIA_1083(phaJ)
RBM: TEF_16395
CCR: CC_0704
CAK: Caul_4051
CSE: Cseg_3677
PZU: PHZ_c3159
SIL: SPO3152
RSP: RSP_2305
JAN: Jann_3364
RDE: RD1_3522
PDE: Pden_3661
DSH: Dshi_2926
PGD: Gal_00894
OTM: OSB_06610(phaJ)
CID: P73_3639
MALG: MALG_02943
RHC: RGUI_1403
SPSE: SULPSESMR1_02408(phaJ)
RMM: ROSMUCSMR3_00429(phaJ)
LVS: LOKVESSMR4R_00151(phaJ)
AHT: ANTHELSMS3_02031(phaJ)
HNE: HNE_0843
ACR: Acry_0584
RRU: Rru_A2964
RRF: F11_15185
RCE: RC1_3580
MAG: amb0831
MAGX: XM1_4442(phaJ)
MAGN: WV31_01260
TMO: TMO_2893
TXI: TH3_16910
MAGQ: MGMAQ_0317(phaJ)
CTC: CTC_00706(maoC)
CTET: BN906_00740(maoC)
CBE: Cbei_2038
CPAT: CLPA_c39950(croR)
CPAE: CPAST_c39950(croR)
CSQ: CSCA_2634
CTYK: CTK_C16670
AMT: Amet_3092
AOE: Clos_1346
CCT: CC1_14800
TTE: TTE0551(MaoC)
APR: Apre_0115
PUF: UFO1_3308
PFT: JBW_01154
ABRA: BN85306540
MBJ: KQ51_00857(phaJ)
TAQ: TO73_0932
BPW: WESB_2381
BIP: Bint_2793
FNU: FN0816
HSW: Hsw_0821
MARN: LN42_02770
GAH: GAH_01713
 » show all
Taxonomy
Reference
1  [PMID:5808333]
  Authors
Moskowitz GJ, Merrick JM.
  Title
Metabolism of poly-beta-hydroxybutyrate. II. Enzymatic synthesis of D-(-)-beta hydroxybutyryl coenzyme A by an enoyl hydrase from Rhodospirillum rubrum.
  Journal
Biochemistry 8:2748-55 (1969)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.55
IUBMB Enzyme Nomenclature: 4.2.1.55
ExPASy - ENZYME nomenclature database: 4.2.1.55
BRENDA, the Enzyme Database: 4.2.1.55
CAS: 37290-82-7

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