KEGG   ENZYME: 4.2.1.56Help
Entry
EC 4.2.1.56                 Enzyme                                 

Name
itaconyl-CoA hydratase;
itaconyl coenzyme A hydratase;
citramalyl-CoA hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
citramalyl-CoA hydro-lyase (itaconyl-CoA-forming)
Reaction(IUBMB)
citramalyl-CoA = itaconyl-CoA + H2O [RN:R02490]
Reaction(KEGG)
Substrate
citramalyl-CoA [CPD:C00904]
Product
itaconyl-CoA [CPD:C00531];
H2O [CPD:C00001]
History
EC 4.2.1.56 created 1972
Pathway
ec00660  C5-Branched dibasic acid metabolism
Orthology
K18290  itaconyl-CoA hydratase
K18291  itaconyl-CoA hydratase / mesaconyl-C4 CoA hydratase
Genes
STM: STM3119
SEO: STM14_3768
SEV: STMMW_30791
SEY: SL1344_3093
SEM: STMDT12_C31720
SEJ: STMUK_3107
SEB: STM474_3268
SEF: UMN798_3389
SETU: STU288_15785
SETC: CFSAN001921_01430
SENI: CY43_16260
SEI: SPC_3186
SEC: SCH_3059(maoC)
SHB: SU5_03617
SED: SeD_A3463
SEG: SG3013
SEL: SPUL_3122
SET: SEN2962
SENA: AU38_15055
SENO: AU37_15065
SENV: AU39_15060
SENQ: AU40_16975
SENL: IY59_15665
SEEP: I137_14920
SENE: IA1_15055
YPE: YPO1927
YPK: y2384
YPA: YPA_1305
YPM: YP_1669(maoC)
YPD: YPD4_1694
YPX: YPD8_1854
YPW: CH59_3723
YPV: BZ15_1615
YPL: CH46_3188
YPS: YPTB1925
YPO: BZ17_546
YPY: YPK_2267
YPB: YPTS_1974
YPQ: DJ40_390
YPU: BZ21_1196
YPR: BZ20_193
YPC: BZ23_1479
YPF: BZ19_1271
PAE: PA0878
PAEV: N297_906
PAEI: N296_906
PAEP: PA1S_22050
PAEM: U769_21420
PAEL: T223_22685
PAEG: AI22_11890
PAEC: M802_902
PAEO: M801_906
PMK: MDS_3407
PPSE: BN5_1312
PPI: YSA_10993
PPUN: PP4_26620
PSB: Psyr_2172
PFL: PFL_2647
PPRO: PPC_2696
PFS: PFLU_3476
PFB: VO64_0589
PSA: PST_1693
PSTT: CH92_08205
PKC: PKB_4382
PSES: PSCI_4464
PSEM: TO66_12940
PSIL: PMA3_18295
MICC: AUP74_02898(paaZ)
LLO: LLO_3026
TMC: LMI_0900
FPZ: LA55_828
FNA: OOM_1390
ADI: B5T_02018
APAC: S7S_06600
AXE: P40_09650
BMA: BMAA1652
BMAL: DM55_3232
BMAE: DM78_4162
BMAQ: DM76_3930
BMAI: DM57_07715
BMAF: DM51_3350
BMAZ: BM44_3168
BMAB: BM45_4007
BPS: BPSS1638
BPSE: BDL_4991
BPSM: BBQ_4503
BPSU: BBN_5091
BPSD: BBX_4157
BPK: BBK_4297
BPSH: DR55_3632
BPSA: BBU_4389
BPSO: X996_5998
BUT: X994_5470
BTD: BTI_4119
BOK: DM82_5766
BOC: BG90_4867
BUL: BW21_6125
BPA: BPP3645
BPAR: BN117_1032
BBR: BB4080
BPT: Bpet0818
BAV: BAV0713
BHO: D560_1020
BHM: D558_1006
TEA: KUI_1574
TEG: KUK_0905
TAS: TASI_1545
TAT: KUM_1150
PUT: PT7_0055
AMIM: MIM_c40140
CCQ: N149_0440
CCF: YSQ_07650
CCY: YSS_02005
CCOI: YSU_06660
CCOF: VC76_02320
BID: Bind_2533
PSF: PSE_3169
SPHM: G432_00490
SPHI: TS85_14845
SFLA: SPHFLASMR4Y_02130(mch)
BLAS: BSY18_3093
ANH: A6F65_00044(paaZ_1)
ADO: A6F68_02606(paaZ_3)
MGA: MGA_1305(maoC)
MGH: MGAH_1305
MGF: MGF_3286
MGN: HFMG06NCA_2805(maoC) HFMG06NCA_2807(maoC)
MGS: HFMG95NCA_2850(maoC) HFMG95NCA_2852(maoC)
MGT: HFMG01NYA_2864(maoC) HFMG01NYA_2866(maoC)
MGV: HFMG94VAA_2923(maoC) HFMG94VAA_2925(maoC)
MGW: HFMG01WIA_2798(maoC) HFMG01WIA_2800(maoC)
MGAC: HFMG06CAA_2975(maoC) HFMG06CAA_2977(maoC)
MGAN: HFMG08NCA_2805(maoC) HFMG08NCA_2807(maoC)
MGNC: HFMG96NCA_3020(maoC) HFMG96NCA_3022(maoC)
MGZ: GCW_92117
MSY: MS53_0536
MLP: MLM_2703
MUL: MUL_4022
MMI: MMAR_4159
KSK: KSE_23690
CACN: RN83_11230
ACIJ: JS278_00425(meh)
 » show all
Taxonomy
Reference
1  [PMID:4284209]
  Authors
Cooper RA, Kornberg HL.
  Title
The utilization of itaconate by Pseudomonas sp.
  Journal
Biochem J 91:82-91 (1964)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.56
IUBMB Enzyme Nomenclature: 4.2.1.56
ExPASy - ENZYME nomenclature database: 4.2.1.56
BRENDA, the Enzyme Database: 4.2.1.56
CAS: 37290-83-8

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