| Entry |
|
|---|
| Name |
long-chain-enoyl-CoA hydratase;
long-chain enoyl coenzyme A hydratase
|
|---|
| Class |
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
 |
|---|
| Sysname |
long-chain-(3S)-3-hydroxyacyl-CoA hydro-lyase
|
|---|
| Reaction(IUBMB) |
a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O [RN: R02685]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
long-chain (3S)-3-hydroxyacyl-CoA
|
|---|
| Product |
long-chain trans-2-enoyl-CoA;
H2O [CPD: C00001]
|
|---|
| Comment |
Acts in the reverse direction. The best substrate is oct-3-enoyl-CoA. Unlike EC 4.2.1.17 enoyl-CoA hydratase, it does not act on crotonoyl-CoA.
|
|---|
| History |
EC 4.2.1.74 created 1981
|
|---|
| Pathway |
|
|---|
| Reference |
|
|---|
| Authors |
Fong JC, Schulz H. |
|---|
| Title |
Purification and properties of pig heart crotonase and the presence of short chain and long chain enoyl coenzyme A hydratases in pig and guinea pig tissues. |
|---|
| Journal |
J Biol Chem 252:542-7 (1977) |
|---|
| Reference |
|
|---|
| Authors |
Schulz H. |
|---|
| Title |
Long chain enoyl coenzyme A hydratase from pig heart. |
|---|
| Journal |
J Biol Chem 249:2704-9 (1974) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.2.1.74 |
| ExPASy - ENZYME nomenclature database: | 4.2.1.74 |
|
|---|
