KEGG ENZYME: 4.2.2.10

ENZYME: 4.2.2.10

Entry

EC 4.2.2.10                 Enzyme

Name

pectin lyase;
pectin trans-eliminase;
endo-pectin lyase;
polymethylgalacturonic transeliminase;
pectin methyltranseliminase;
pectolyase;
PL;
PNL;
PMGL

Class

Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides

Sysname

(1->4)-6-O-methyl-alpha-D-galacturonan lyase

Reaction(IUBMB)

Eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their non-reducing ends

Comment

Favours pectin, the methyl ester, over pectate, the anion (which is the preferred substrate of EC 4.2.2.2, pectate lyase). Demethylation progressively slows its action; it can nevertheless cleave on either side of a demethylated residue if the residue at the other end of the scissile bond is methylated.

History

EC 4.2.2.10 created 1972, modified 2002

Orthology

K01732

pectin lyase

K19551

pectate lyase C

Genes

MQU:

128994652

FOC:	113203564 113207248 113207256 113207878 113211042 113211651 113214490

TPAL:

117642005 117642772 117645164 117649575 117649691 117652784 117652785 117653402

MTM:	MYCTH_52332

TMN:	UCRPA7_7400

FGR:	FGSG_01607 FGSG_03121 FGSG_03483 FGSG_13834

FPU:	FPSE_02103 FPSE_02805 FPSE_09996 FPSE_10251

FPOA:

FPOAC1_001728 FPOAC1_005478 FPOAC1_005867

FVN:	FVRRES_01942 FVRRES_04214 FVRRES_04281 FVRRES_06038 FVRRES_06476 FVRRES_10623

FVR:	FVEG_03470 FVEG_05700 FVEG_09702 FVEG_12209 FVEG_13711

FOX:	FOXG_05617 FOXG_11096 FOXG_13331 FOXG_16516

NHE:	NECHADRAFT_106390 NECHADRAFT_122319 NECHADRAFT_16877 NECHADRAFT_30203 NECHADRAFT_44358 NECHADRAFT_78318 NECHADRAFT_82428

FFC:	NCS54_00021600 NCS54_00450600 NCS54_00450800 NCS54_00777400 NCS54_01191100

FKR:	NCS57_00019600 NCS57_00456500 NCS57_00819500 NCS57_00925200 NCS57_01182500

FMU:	J7337_000260 J7337_002074 J7337_003486 J7337_007540 J7337_012255

VAL:	VDBG_02740 VDBG_04520 VDBG_05494 VDBG_08488 VDBG_09088

VDA:	VDAG_03656 VDAG_07144 VDAG_07238 VDAG_08154 VDAG_08734

CFJ:	CFIO01_02126 CFIO01_03438 CFIO01_05967 CFIO01_09235 CFIO01_09971

CLUP:

CLUP02_02154 CLUP02_02336 CLUP02_15812 CLUP02_16724 CLUP02_17011

CHIG:

CH63R_04888 CH63R_05252 CH63R_06509 CH63R_06781 CH63R_10857 CH63R_10984

CDET:

87941952(CDEST_05449) 87942327(CDEST_05824) 87943938(CDEST_07435) 87944064(CDEST_07561) 87947892(CDEST_11392) 87948174(CDEST_11674)

ELA:	UCREL1_11485 UCREL1_9277

PFY:	PFICI_01623 PFICI_01708 PFICI_01983 PFICI_03409 PFICI_03426 PFICI_04109 PFICI_04539 PFICI_06619 PFICI_06827 PFICI_10448 PFICI_12586 PFICI_13249

SSL:	SS1G_00040 SS1G_07942 SS1G_10071

BFU:	BCIN_03g00280 BCIN_03g07360 BCIN_08g03820 BCIN_12g05620 BCIN_14g03430

MBE:	MBM_06898 MBM_07244

PSCO:

LY89DRAFT_712426

GLZ:	GLAREA_08563 GLAREA_10132

ANI:	ANIA_02331 ANIA_02569 ANIA_04882 ANIA_09439

AFM:	AFUA_2G00800 AFUA_5G10170 AFUA_5G10380 AFUA_7G05030

ACT:	ACLA_013470 ACLA_094210

NFI:	NFIA_026110 NFIA_033080 NFIA_076850 NFIA_077100

AOR:	AO090003001295 AO090010000030 AO090010000087 AO090010000504 AO090012000121 AO090012000451 AO090103000463 AO090138000204

ANG:	An03g00190(pelB) An11g04030 An14g04370(pelA) An15g07160 An19g00270(pelD)

AFV:	AFLA_000385 AFLA_001835 AFLA_002173 AFLA_012256 AFLA_013066 AFLA_013566 AFLA_013625 AFLA_013986

ALUC:

AKAW2_10010A AKAW2_21617S AKAW2_41098A AKAW2_50059S AKAW2_60071S AKAW2_80377A

ACHE:

ACHE_11923A ACHE_41043S

APUU:

APUU_12262S APUU_20380S APUU_20673A APUU_20680A(PELF1) APUU_30985S

PCS:	N7525_001567 N7525_007571 N7525_008471

PDP:	PDIP_08080 PDIP_57790

POU:	POX_d05538 POX_g09173

TMF:	EYB26_009773

TRG:	TRUGW13939_09491

PNO:	SNOG_05296

PTE:	PTT_10459 PTT_17181

PTRR:

6338316(PtrM4_008410) 6342155(PtrM4_093880)

BZE:	COCCADRAFT_105851 COCCADRAFT_40410

BSC:	COCSADRAFT_22904 COCSADRAFT_350939

BOR:	COCMIDRAFT_8927 COCMIDRAFT_90152

AALT:

CC77DRAFT_1098346 CC77DRAFT_215351 CC77DRAFT_566682 CC77DRAFT_932317 CC77DRAFT_965788

ADAC:

96080355(ACET3X_000033) 96084254(ACET3X_003932) 96086011(ACET3X_005689) 96089977(ACET3X_009655)

ARAB:

EKO05_0002162 EKO05_0007329 EKO05_0008498 EKO05_0008678

PFJ:	MYCFIDRAFT_134058

CBET:

CB0940_08607

NPA:	UCRNP2_10323 UCRNP2_1557 UCRNP2_1907 UCRNP2_5357

TML:	GSTUM_00006239001

SHS:	STEHIDRAFT_122801 STEHIDRAFT_140400

HIR:	HETIRDRAFT_104663

PSQ:	PUNSTDRAFT_131044

RSX:	RhiXN_03621 RhiXN_05576 RhiXN_06449 RhiXN_06450 RhiXN_08067 RhiXN_08068 RhiXN_08601 RhiXN_08667 RhiXN_08671 RhiXN_08672 RhiXN_08673 RhiXN_08679 RhiXN_08680 RhiXN_08681 RhiXN_12180

UMA:	UMAG_04708

PFP:	PFL1_00473

SGRA:

EX895_000259

PGR:	PGTG_11403 PGTG_12344

PTRC:

PtA15_2A368 PtA15_6A726 PtA15_7A476 PtA15_9A559

PSTR:

Pst134EA_029198 Pst134EA_029199

MLR:	MELLADRAFT_108110 MELLADRAFT_44084 MELLADRAFT_72436 MELLADRAFT_93893

PIF:	PITG_00872 PITG_07680 PITG_08555 PITG_08561 PITG_08563 PITG_08564 PITG_09457 PITG_09465 PITG_09466 PITG_09467 PITG_21462 PITG_21463 PITG_21499

PSOJ:

PHYSODRAFT_246459 PHYSODRAFT_262301 PHYSODRAFT_263887 PHYSODRAFT_264003 PHYSODRAFT_329957 PHYSODRAFT_335254 PHYSODRAFT_335255 PHYSODRAFT_371911 PHYSODRAFT_434567 PHYSODRAFT_489646 PHYSODRAFT_490300 PHYSODRAFT_491398 PHYSODRAFT_510673 PHYSODRAFT_510956 PHYSODRAFT_512339 PHYSODRAFT_513650 PHYSODRAFT_513690 PHYSODRAFT_520929 PHYSODRAFT_546965

SPAR:

SPRG_04286 SPRG_05353 SPRG_18619

SSAR:

SSARUM_004845

SERA:

Ser39006_022235

SERQ:

CWC46_22245

PROD:

PCO85_02965

ECA:	ECA1499(pnl)

PATR:

EV46_07595

PATO:

GZ59_15370(pnl)

PCT:

PC1_1371

PCC:	PCC21_014030

PCV:	BCS7_06950

PWA:	Pecwa_1777

PPAR:

A8F97_09890

PEC:

W5S_1691

PWS:	A7983_22620

PPOA:

BJK05_02135

PBRA:

B5S52_14620

PPUJ:

E2566_07525

PARI:

I2D83_15145

PVZ:	OA04_29050(pnl)

PPOO:

LW347_07475

PACB:

M9782_09410

PCOA:

PJ912_21860

PPEU:

DUT67_14465

DDD:	Dda3937_03551 Dda3937_04108(pnlH)

DZE:	Dd1591_3306

DZC:	W909_02890

DSO:	A4U42_12055

CED:	LH89_09345

DFN:	CVE23_03390

DDQ:	DDI_0365 DDI_2942

DDA:	Dd703_3378

EAM:	EAMY_0653(eop2)

EAY:	EAM_2780(eop2)

EPE:	CI789_02390

ERWI:

GN242_05955

ETP:	LU633_25005

ERP:	LJN55_16490

PST:	PSPTO_4101(hopAK1)

PSB:

Psyr_3839

PSYR:

N018_06330

PSP:	PSPPH_1424(hopAK1)

PSAV:

PSA3335_06735

PAMG:

BKM19_022740

PAVL:

BKM03_22235

PCAB:

JGS08_19790

PCOF:

POR16_06175

PTRE:

I9H09_17820

PSYI:

MME58_19670

PAST:

N015_20185

PFS:	PFLU_2293(pnl)

PTV:	AA957_03130

POI:	BOP93_21145

PMAB:

U0037_11520

PTRT:

HU722_0011775

PSKU:

KUIN1_38010

CELL:

CBR65_13510

SCL:	sce4938(yvpA)

SCU:	SCE1572_29890 SCE1572_50445

PAUU:

E8A73_005035

VBH:	CMV30_13220

CPI:

Cpin_0715

CHIH:

GWR21_19190

BSU:	BSU18650(pelB) BSU34950(pelC)

BSR:	I33_2093 I33_3626

BSL:	A7A1_2451 A7A1_2716

BSH:	BSU6051_18650(pelB) BSU6051_34950(pelC)

BSY:	I653_09705 I653_17020

BSUT:

BSUB_02005(pelB) BSUB_03725(pelC)

BSUL:

BSUA_02005(pelB) BSUA_03725(pelC)

BSUS:

Q433_11025 Q433_19135

BSO:	BSNT_10122(yvpA)

BSN:	BSn5_00690 BSn5_08410

BSQ:	B657_18650(pelB) B657_34950(pelC)

BSX:	C663_1929(pelB) C663_3384(pelC)

BSP:	U712_09820 U712_17500

BSS:	BSUW23_09955(pelB) BSUW23_17130(pelC)

BST:	GYO_2245 GYO_3832

BIT:	BIS30_07100 BIS30_20510

BLI:	BL00361(pelB) BL03597(yvpA)

BLD:	BLi03053(pelB) BLi03741(pelC)

BLH:	BaLi_c31330(pelB) BaLi_c37440(pelC)

BAY:	RBAM_036320

BAQ:	BACAU_3655(pelB)

BYA:	BANAU_3815(pelB)

BQY:	MUS_4319(pelB)

BAMP:

B938_18645

BAML:

BAM5036_3554(pelB)

BAMA:

RBAU_3765(pelB)

BAMN:

BASU_3548(pelB)

BAMB:

BAPNAU_3827(pelB)

BAMT:

AJ82_20540

BAMY:

V529_39070(pelB)

BMP:	NG74_03810(pelB)

BAO:	BAMF_3745(pelB)

BAZ:	BAMTA208_19805(pelB)

BQL:	LL3_04068(pelB)

BXH:	BAXH7_04063(pelB)

BAMI:

KSO_000885

BAMC:

U471_37900

BAMF:

U722_19355

BSIA:

CWD84_00970

BAE:	BATR1942_15380 BATR1942_17615

BVM:	B9C48_18540

BSON:

S101395_00662(pelC)

BHT:	DIC78_13610 DIC78_21330

BMOJ:

HC660_19240(pelB) HC660_33800(pelC)

BTEQ:

G4P54_10705

BIQ:	AN935_09735 AN935_17585

BSTR:

QI003_10105 QI003_13535 QI003_20950(pelC)

BGY:	BGLY_4139(pelC)

BCAB:

EFK13_10330 EFK13_17955(pelC)

BRY:	M0696_10090 M0696_17695(pelC)

BJS:	MY9_2037 MY9_3544

BACP:

SB24_10585

BACB:

OY17_01825

BACY:

QF06_08450 QF06_15860

BACL:

BS34A_20660(pelB) BS34A_38050(pelC)

BALM:

BsLM_1988 BsLM_3502

BACS:

AUL54_11555

BAFC:

K3G25_11280

BGI:	BGM20_03895 BGM20_11605

GRC:	GI584_16335

GCS:	MUN88_01580

GSM:	MUN87_18070

PPY:	PPE_00899 PPE_01380

PPM:	PPSC2_04665(yvpA) PPSC2_07120(pelB)

PPO:	PPM_0875(yvpA) PPM_1351(pelB)

PPOL:

X809_04310 X809_07780

PPQ:	PPSQR21_009310 PPSQR21_015120

PPOY:

RE92_04765 RE92_07300

PMS:	KNP414_00430(pelA)

PMQ:	PM3016_378

PMW:

B2K_01935

PTA:	HPL003_12415 HPL003_15530

PBD:	PBOR_19040

PAEN:

P40081_26185

PAEQ:

R50912_24135

PAEA:

R70723_20915

PPEO:

ABE82_04465 ABE82_07575

PBV:	AR543_00990 AR543_13505

PXL:	BS614_08300 BS614_25720

PDH:	B9T62_22105

PKB:	B4V02_08085 B4V02_17750 B4V02_20590

PAIH:

ASL14_07070

PVO:	PVOR_08465

PLEN:

EIM92_15835

PBAC:

HUB98_09670 HUB98_21565

PTRI:

KDC22_22780

PKA:	PQ456_11795

PUI:	PUW25_04550

PMAH:

PTQ21_09655 PTQ21_28655

PAMY:

P9222_14385 P9222_33115

PMAE:

LMZ02_11930

PWN:	QNH46_12910

PPOG:

QPK24_07895 QPK24_09845 QPK24_13325

PNK:	AASFL403_07175

PPAB:

KET34_04735 KET34_25840

PGLU:

A3958_15055

PLZH:

C0638_00545 C0638_03235

PEZZ:

HW560_00695 HW560_13935

CLT:	CM240_1020 CM240_3282

RCH:

RUM_06550

ACEL:

acsn021_33990(pelC)

» show all

Reference

Authors

Albersheim P, Neukom H, Deuel H.

Title

Uber die Bildung von ungesattigten Abbauprodukten durch ein pekinabbauendes Enzym.

Journal

Helv Chim Acta 43:1422-1426 (1960)

Reference

2 [PMID:9195887]

Authors

Mayans O, Scott M, Connerton I, Gravesen T, Benen J, Visser J, Pickersgill R, Jenkins J.

Title

Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases.

Journal

Structure 5:677-89 (1997)
DOI:10.1016/S0969-2126(97)00222-0

Sequence

[ang:An14g04370]

Reference

Authors

Kester HCM, Visser J.

Title

Purification and characterization of pectin lyase B, a novel pectinolytic enzyme from Aspergillus niger.

Journal

FEMS Microbiol Lett 120:63-68 (1994)

Reference