KEGG   ENZYME: 4.2.2.2Help
Entry
EC 4.2.2.2                  Enzyme                                 

Name
pectate lyase;
polygalacturonic transeliminase;
pectic acid transeliminase;
polygalacturonate lyase;
endopectin methyltranseliminase;
pectate transeliminase;
endogalacturonate transeliminase;
pectic acid lyase;
pectic lyase;
alpha-1,4-D-endopolygalacturonic acid lyase;
PGA lyase;
PPase-N;
endo-alpha-1,4-polygalacturonic acid lyase;
polygalacturonic acid lyase;
pectin trans-eliminase;
Polygalacturonic acid trans-eliminase
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
BRITE hierarchy
Sysname
(1->4)-alpha-D-galacturonan lyase
Reaction(IUBMB)
Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends [RN:R08694]
Reaction(KEGG)
Comment
Favours pectate, the anion, over pectin, the methyl ester (which is the preferred substrate of EC 4.2.2.10, pectin lyase).
History
EC 4.2.2.2 created 1965 as EC 4.2.99.3, transferred 1972 to EC 4.2.2.2, modified 2002
Pathway
ec00040  Pentose and glucuronate interconversions
Orthology
K01728  pectate lyase
K19551  pectate lyase C
K22539  pectate lyase
Genes
FCD: 110843205 110850415 110857634 110862776
ATH: AT1G04680 AT1G11920 AT1G14420(AT59) AT1G30350 AT1G67750 AT2G02720 AT3G01270 AT3G07010 AT3G09540 AT3G24230 AT3G24670 AT3G27400 AT3G53190 AT3G54920(PMR6) AT3G55140 AT4G13210 AT4G13710 AT4G22080(RHS14) AT4G22090 AT4G24780 AT5G04310 AT5G09280 AT5G15110 AT5G48900 AT5G55720 AT5G63180
ALY: ARALYDRAFT_312221 ARALYDRAFT_333008 ARALYDRAFT_355442 ARALYDRAFT_359757 ARALYDRAFT_471616 ARALYDRAFT_475879 ARALYDRAFT_477401 ARALYDRAFT_478021 ARALYDRAFT_478272 ARALYDRAFT_484177 ARALYDRAFT_485694 ARALYDRAFT_485907 ARALYDRAFT_485935 ARALYDRAFT_487211 ARALYDRAFT_487738 ARALYDRAFT_488352 ARALYDRAFT_492364 ARALYDRAFT_492665 ARALYDRAFT_494953 ARALYDRAFT_495658 ARALYDRAFT_496502 ARALYDRAFT_664577 ARALYDRAFT_680782 ARALYDRAFT_887643 ARALYDRAFT_898940 ARALYDRAFT_899063
CRB: 17874788 17875888 17876043 17877435 17878980 17879020 17880244 17880460 17881129 17881712 17884013 17886078 17886096 17886525 17886622 17887442 17891961 17892213 17892428 17892646 17893880 17894545 17897840 17898870 17900129
CSAT: 104701382 104702913 104705786 104708191 104708688 104709867 104710180 104710564 104711877 104712101 104712139 104717795 104718108 104719084 104719142 104722501 104722827 104723194 104723820 104723932 104725373 104726121 104726924 104726926 104728129 104729714 104730966 104731307 104732207 104732214 104732336 104732455 104734443 104735528 104737902 104738994 104739841 104740907 104741631 104741633 104744232 104744886 104745124 104747027 104750583 104753331 104754610 104755452 104755738 104757379 104760870 104761621 104761624 104762456 104762495 104763832 104764407 104764652 104766315 104766397 104768620 104769751 104770759 104772174 104773181 104777061 104779605 104779971 104781172 104781362 104781391 104787793 104789389 104789709 104790042 104790395 104791583 104791770 104791798 109131746
EUS: EUTSA_v10010534mg EUTSA_v10015832mg EUTSA_v10016093mg EUTSA_v10020972mg
BRP: 103827511 103828610 103828688 103829999 103831011 103831201 103833389 103833411 103834235 103834896 103836073 103836561 103836991 103837270 103837461 103839439 103841243 103841403 103842969 103843635 103844229 103846441 103847197 103847312 103850082 103850282 103850968 103851864 103852424 103853982 103854237 103854567 103855563 103856110 103858923 103859732 103860809 103861505 103862557 103863187 103863605 103863641 103870538 103870710 103872042 103872043 103872235 103873738 103875221
BNA: 106345454 106347564 106347875 106351296 106352403 106352880 106353973 106356689 106359728 106360208 106361318 106363861 106364615 106364980 106365441 106365801 106366185 106367044 106367682 106367786 106368660 106369886 106370559 106370994 106372536 106372688 106373282 106374536 106374537 106375499 106375788 106375976 106378857 106379411 106379656 106379864 106379906 106380922 106380924 106381139 106382022 106382476 106382584 106386392 106386806 106388660 106391282 106394864 106399678 106399968 106402512 106403184 106409219 106409464 106409544 106410328 106410439 106415745 106416640 106417790 106418398 106419261 106419263 106419852 106421771 106422643 106424219 106426949 106427406 106428402 106428627 106428855 106430092 106430295 106430312 106433413 106436935 106438903 106439158 106439876 106440777 106440778 106442074 106442321 106443116 106443426 106443623 106445342 106445845 106449446 106450598 106450745 106452444 106452749 106452978 106454552 111197831 111200419 111202047 111204226 111204301 111204757 111207429 111208330 111209450 111211070 111211421 111212602 111212758
BOE: 106292706 106293450 106293841 106294248 106295034 106296029 106296039 106296620 106296651 106297447 106297735 106300297 106300351 106301626 106302079 106302135 106304149 106304858 106304927 106305942 106307150 106307708 106308326 106310394 106312025 106312230 106312405 106312523 106313749 106316056 106316304 106318226 106318304 106318675 106319450 106320315 106324444 106324966 106325607 106325780 106325844 106327875 106329526 106332491 106332735 106333129 106335147 106336636 106336928 106341847
THJ: 104800140 104801050 104801785 104804601 104805137 104805202 104805355 104805450 104806314 104807066 104807772 104808727 104808774 104809484 104809976 104810004 104811609 104814007 104816432 104818203 104818939 104819344 104821042 104822370 104826108 104826900 104827001 104827349
LJA: Lj0g3v0016749.1(Lj0g3v0016749.1) Lj0g3v0016749.2(Lj0g3v0016749.2) Lj0g3v0081679.1(Lj0g3v0081679.1) Lj0g3v0146639.1(Lj0g3v0146639.1) Lj0g3v0207779.1(Lj0g3v0207779.1) Lj0g3v0293729.1(Lj0g3v0293729.1) Lj1g3v3476140.1(Lj1g3v3476140.1) Lj1g3v4616550.1(Lj1g3v4616550.1) Lj4g3v0134630.1(Lj4g3v0134630.1) Lj4g3v1389340.1(Lj4g3v1389340.1) Lj4g3v1614780.1(Lj4g3v1614780.1) Lj5g3v0615090.1(Lj5g3v0615090.1) Lj5g3v0670070.1(Lj5g3v0670070.1) Lj5g3v0670070.2(Lj5g3v0670070.2) Lj5g3v2220310.1(Lj5g3v2220310.1) Lj5g3v2288630.1(Lj5g3v2288630.1) Lj6g3v0108680.1(Lj6g3v0108680.1) Lj6g3v0108680.2(Lj6g3v0108680.2)
DOSA: Os01t0546800-01(Os01g0546800) Os01t0837100-00(Os01g0837100) Os02t0214400-01(Os02g0214400) Os05t0293500-01(Os05g0293500) Os06t0144200-01(Os06g0144200) Os06t0144900-01(Os06g0144900) Os06t0583900-01(Os06g0583900) Os06t0584000-00(Os06g0584000) Os08t0286100-00(Os08g0286100) Os10t0457200-00(Os10g0457200)
ATS: 109747561(LOC109747561) 109748940(LOC109748940) 109757500(LOC109757500) 109759162(LOC109759162) 109767069(LOC109767069) 109772683(LOC109772683) 109776699(LOC109776699) 109781597(LOC109781597) 109783195(LOC109783195)
NTE: NEUTE1DRAFT124186(NEUTE1DRAFT_124186)
ANG: ANI_1_102174(An10g00870)
ABP: AGABI1DRAFT78861(AGABI1DRAFT_78861) AGABI1DRAFT87431(AGABI1DRAFT_87431)
ABV: AGABI2DRAFT139877(AGABI2DRAFT_139877) AGABI2DRAFT195581(AGABI2DRAFT_195581)
KOX: KOX_16835
KOE: A225_2215
YPE: YPO3994(pelY)
YPK: y3834
YPH: YPC_4503(pelY)
YPA: YPA_3822
YPN: YPN_3644
YPM: YP_3357(pelY)
YPZ: YPZ3_2172(pelY)
YPD: YPD4_3514(pelY)
YPX: YPD8_3520(pelY)
YPW: CH59_1943(pelY)
YPJ: CH55_2674(pelY)
YPV: BZ15_3710(pelY)
YPL: CH46_1062(pelY)
YPS: YPTB3834(pelY)
YPO: BZ17_2750(pelY)
YPY: YPK_0096
YPB: YPTS_4050
YPQ: DJ40_2560(pelY)
YPU: BZ21_3188(pelY)
YPR: BZ20_2257(pelY)
YPC: BZ23_3463(pelY)
YPF: BZ19_3322(pelY)
YEN: YE4069(pelY)
YEY: Y11_31271
YEW: CH47_3664(pelY)
YET: CH48_1520(pelY)
YEE: YE5303_39231(pelY)
YFR: AW19_3388(pelY)
YIN: CH53_1625(pelY)
YKR: CH54_2402
YRO: CH64_2472(pelY)
ECA: ECA2135 ECA3112 ECA4067(pelA) ECA4068(pelB) ECA4069(pelC)
TPTY: NCTC11468_02262(pnl)
XCC: XCC0644(pel) XCC0645(pel) XCC2815(pelB)
XCA: xcc-b100_1345(pel1) xcc-b100_3710(pel2) xcc-b100_3711(pel3)
XCV: XCV2278 XCV2569 XCV3132(pel1) XCV3687(pel2)
XAC: XAC2373(pel) XAC2986(pelB) XAC3562(pel)
XCI: XCAW_02038(pel) XCAW_03264(pelB) XCAW_04262(pel)
XOO: XOO0821(pel) XOO2265
XOM: XOO0747(XOO0747) XOO2130(XOO2130)
XOR: XOC_2506 XOC_3823(pel)
XPH: XppCFBP6546_01165(XppCFBP6546P_01165) XppCFBP6546_16520(XppCFBP6546P_16520) XppCFBP6546_20840(XppCFBP6546P_20840)
PFS: PFLU_3229
PSES: PSCI_1510
CJA: CJA_0533(pel1B) CJA_1277(pelC) CJA_2914(pel3C)
SDE: Sde_3007(pel3C) Sde_3448(pel1D)
SAGA: M5M_10280
HCH: HCH_03164
BPH: Bphy_7394
BPT: Bpet0241
AXX: ERS451415_02728(pelA)
ODI: ODI_R1001
AAV: Aave_3434
AAA: Acav_3299
SCL: sce4938(yvpA)
SME: SM_b21239
SMD: Smed_6139
BSU: BSU07560(pel) BSU34950(pelC)
BSH: BSU6051_07560(pel) BSU6051_34950(pelC)
BSUT: BSUB_00830(pel) BSUB_03725(pelC)
BSUL: BSUA_00830(pel) BSUA_03725(pelC)
BSS: BSUW23_03840(pel) BSUW23_17130(pelC)
BSO: BSNT_07133(pel) BSNT_10122(yvpA)
BSQ: B657_07560(pel) B657_34950(pelC)
BSX: C663_0779(pel) C663_3384(pelC)
BLI: BL03597(yvpA) BL03760(pel)
BLD: BLi01404(pel) BLi03741(pelC)
BLH: BaLi_c15450(pel) BaLi_c37440(pelC) BaLi_c41260(pelA)
BAY: RBAM_007720(pel)
BAQ: BACAU_0741(pel)
BYA: BANAU_0687(pel)
BAMP: B938_03665
BAML: BAM5036_0685(pel)
BAMA: RBAU_0744(pel)
BAMN: BASU_0721(pel)
BAMB: BAPNAU_0696(pel)
BAMT: AJ82_04280
BAMY: V529_07080(pel)
BMP: NG74_00761(pel)
BAO: BAMF_0717(pel)
BAZ: BAMTA208_03390(pel)
BQL: LL3_00769(pel)
BXH: BAXH7_00714(pel)
BQY: MUS_0758(pel)
BAMI: KSO_015960
BAMC: U471_07520
BAMF: U722_03795
BHA: BH0698
BCL: ABC0063(pelB) ABC1141
BPU: BPUM_3515
BPUM: BW16_18625
BPUS: UP12_18040
BACW: QR42_17605
BACP: SB24_06025
BACB: OY17_06485
BACL: BS34A_08530(pel) BS34A_38050(pelC)
BEO: BEH_10455
BGY: BGLY_1397 BGLY_1398(pel1) BGLY_4139(pelC) BGLY_4478(pel2)
PPM: PPSC2_04665(yvpA) PPSC2_18545(pel1)
PPO: PPM_0875(yvpA) PPM_3731(pel1)
MPS: MPTP_1720
LCI: LCK_00931(pel)
LKI: LKI_06180
HSC: HVS_04885(pelA)
CCE: Ccel_2243
BPB: bpr_I2372(pel1A)
ABRA: BN85302810
SCO: SCO1110(2SCG38.03) SCO1880(SCI39.27c)
SGR: SGR_216
SFI: SFUL_2908
SRW: TUE45_01468(pel_1) TUE45_01469(pelA_1) TUE45_02368(pel_2) TUE45_03929(pel_3)
SLE: sle_02110(sle_02110) sle_13560(sle_13560) sle_13570(sle_13570) sle_13580(sle_13580) sle_13590(sle_13590) sle_52470(sle_52470) sle_52540(sle_52540) sle_52570(sle_52570) sle_60010(sle_60010)
SRN: A4G23_00514(pelA) A4G23_01105(pel_2) A4G23_02893(pel_3)
SNR: SNOUR_42125(pel)
CMC: CMN_02654
JDE: Jden_0329
IDO: I598_2089(pelA_1) I598_2471(pel_2)
CFL: Cfla_1313
TFU: Tfu_0153
NDA: Ndas_5013
TCU: Tcur_2436
SRO: Sros_1493
SEN: SACE_4362
AMD: AMED_4436(pel) AMED_4437(pel)
AMM: AMES_4382(pel) AMES_4383(pel)
AMZ: B737_4382(pel) B737_4383(pel)
AHG: AHOG_21740(pel) AHOG_21745(pelA) AHOG_21820(pelC)
RBA: RB3417 RB5312(pel) RB5316
ABAC: LuPra_01386(pel)
FSC: FSU_0577
FLN: FLA_1427
HSW: Hsw_1036
FJO: Fjoh_2566
FJG: BB050_00082(pelE) BB050_04246(pelA)
FBA: FIC_01877
TMA: TM0433
TMW: THMA_0439
TMQ: THMB_0439
TMX: THMC_0439
TRQ: TRQ2_0511
TLE: Tlet_1137
DTU: Dtur_0431
 » show all
Taxonomy
Reference
1  [PMID:13860094]
  Authors
ALBERSHEIM P, KILLIAS U.
  Title
Studies relating to the purification and properties of pectin transeliminase.
  Journal
Arch Biochem Biophys 97:107-15 (1962)
DOI:10.1016/0003-9861(62)90050-4
Reference
2  [PMID:14235514]
  Authors
EDSTROM RD, PHAFF HJ.
  Title
PURIFICATION AND CERTAIN PROPERTIES OF PECTIN TRANS-ELIMINASE FROM ASPERGILLUS FONSECAEUS.
  Journal
J Biol Chem 239:2403-8 (1964)
Reference
3  [PMID:14235515]
  Authors
EDSTROM RD, PHAFF HJ.
  Title
ELIMINATIVE CLEAVAGE OF PECTIN AND OF OLIGOGALACTURONIDE METHYL ESTERS BY PECTIN TRANS-ELIMINASE.
  Journal
J Biol Chem 239:2409-15 (1964)
Reference
4  [PMID:13727438]
  Authors
NAGEL CW, VAUGHN RH.
  Title
The degradation of oligogalacturonides by the polygalacturonase of Bacillus polymyxa.
  Journal
Arch Biochem Biophys 94:328-32 (1961)
DOI:10.1016/0003-9861(61)90047-9
Reference
5  [PMID:6035509]
  Authors
Nasuno S, Starr MP.
  Title
Polygalacturonic acid trans-eliminase of Xanthomonas campestris.
  Journal
Biochem J 104:178-85 (1967)
Reference
6  [PMID:9195887]
  Authors
Mayans O, Scott M, Connerton I, Gravesen T, Benen J, Visser J, Pickersgill R, Jenkins J.
  Title
Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases.
  Journal
Structure 5:677-89 (1997)
DOI:10.1016/S0969-2126(97)00222-0
Other DBs
ExplorEnz - The Enzyme Database: 4.2.2.2
IUBMB Enzyme Nomenclature: 4.2.2.2
ExPASy - ENZYME nomenclature database: 4.2.2.2
BRENDA, the Enzyme Database: 4.2.2.2
CAS: 9015-75-2

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