KEGG   ENZYME: 4.2.2.9Help
Entry
EC 4.2.2.9                  Enzyme                                 

Name
pectate disaccharide-lyase;
pectate exo-lyase;
exopectic acid transeliminase;
exopectate lyase;
exopolygalacturonic acid-trans-eliminase;
PATE;
exo-PATE;
exo-PGL;
exopolygalacturonate lyase (ambiguous);
pelW (gene name);
pelX (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on polysaccharides
BRITE hierarchy
Sysname
(1->4)-alpha-D-galacturonan reducing-end-disaccharide-lyase
Reaction(IUBMB)
(1,4-alpha-D-galacturonosyl)n = (1,4-alpha-D-galacturonosyl)n-2 + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [RN:R02361 R06240]
Reaction(KEGG)
Substrate
(1,4-alpha-D-galacturonosyl)n [CPD:C00470]
Product
(1,4-alpha-D-galacturonosyl)n-2;
4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate [CPD:C06118]
Comment
The enzyme catalyses the eliminative cleavage of an unsaturated disaccharide from the reducing end of homogalacturonan (the backbone of smooth regions of pectate, also known as de-esterified pectin).
History
EC 4.2.2.9 created 1972, modified 2002
Pathway
ec00040  Pentose and glucuronate interconversions
Orthology
K01731  pectate disaccharide-lyase
K22994  pectate disaccharide-lyase
Genes
ECC: c0323
EAB: ECABU_c02850
ELC: i14_0311
ELD: i02_0311
ENT: Ent638_4134
EAS: Entas_4441
ECAN: CWI88_22765
ENR: H650_15125
ENF: AKI40_4954
KOX: KOX_06695
KOE: A225_5810
EBF: D782_4530
YPE: YPO1723(kdgC)
YPK: y1885
YPH: YPC_2093(kdgC)
YPA: YPA_1798
YPN: YPN_1907
YPM: YP_1748(pelW)
YPZ: YPZ3_1982(pelW)
YPD: YPD4_1533(pelW)
YPX: YPD8_2019(pelW)
YPW: CH59_111
YPJ: CH55_525
YPV: BZ15_1826
YPL: CH46_3400
YPS: YPTB2358(pelW)
YPO: BZ17_98
YPY: YPK_1802
YPB: YPTS_2432
YPQ: DJ40_4215
YPU: BZ21_1644
YPR: BZ20_3849
YPC: BZ23_1930
YPF: BZ19_1721
YEN: YE1886(kdgC)
YEY: Y11_07571
YEW: CH47_1320
YET: CH48_3593
YEE: YE5303_20681(kdgC)
YAL: AT01_227
YFR: AW19_1431
YIN: CH53_4262
YKR: CH54_231
YRO: CH64_775
RAA: Q7S_22851
ECA: ECA2402(pelW) ECA4510(pelX)
PATO: GZ59_21550(pelW) GZ59_46090(pelX)
DDD: Dda3937_00143(pelX) Dda3937_03361(pelW)
MSU: MS1742
ASU: Asuc_1469
VPA: VPA0086
PPR: PBPRB1725(PELX)
BHA: BH0494(pelX)
BKW: BkAM31D_11885(pelX)
EFU: HMPREF0351_10547(fms12)
EDU: LIU_03960
MPX: MPD5_0537
CSR: Cspa_c44020(pelX)
CSS: Cst_c01730(pelX)
CSD: Clst_0166(pelA)
FPR: FP2_32150
TIT: Thit_1727
ABRA: BN85302860
IDO: I598_2859(pelX)
 » show all
Taxonomy
Reference
1  [PMID:14188174]
  Authors
MACMILLAN JD, VAUGHN RH.
  Title
PURIFICATION AND PROPERTIES OF A POLYGALACTURONIC ACID-TRANS-ELIMINASE PRODUCED BY CLOSTRIDIUM MULTIFERMENTANS.
  Journal
Biochemistry 3:564-72 (1964)
Reference
2  [PMID:10049400]
  Authors
Shevchik VE, Kester HC, Benen JA, Visser J, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
Characterization of the exopolygalacturonate lyase PelX of Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:1652-63 (1999)
  Sequence
Reference
3  [PMID:10383957]
  Authors
Shevchik VE, Condemine G, Robert-Baudouy J, Hugouvieux-Cotte-Pattat N
  Title
The exopolygalacturonate lyase PelW and the oligogalacturonate lyase Ogl, two cytoplasmic enzymes of pectin catabolism in Erwinia chrysanthemi 3937.
  Journal
J Bacteriol 181:3912-9 (1999)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 4.2.2.9
IUBMB Enzyme Nomenclature: 4.2.2.9
ExPASy - ENZYME nomenclature database: 4.2.2.9
BRENDA, the Enzyme Database: 4.2.2.9
CAS: 37290-87-2

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