KEGG   ENZYME: 4.2.3.130Help
Entry
EC 4.2.3.130                Enzyme                                 

Name
tetraprenyl-beta-curcumene synthase;
ytpB (gene name)
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
all-trans-heptaprenyl-diphosphate diphosphate-lyase (cyclizing, tetraprenyl-beta-curcumene-forming)
Reaction(IUBMB)
all-trans-heptaprenyl diphosphate = tetraprenyl-beta-curcumene + diphosphate [RN:R10009]
Reaction(KEGG)
Substrate
all-trans-heptaprenyl diphosphate [CPD:C04216]
Product
tetraprenyl-beta-curcumene [CPD:C20276];
diphosphate [CPD:C00013]
Comment
Isolated from Bacillus subtilis. This sesquarterpene is present in a number of Bacillus species.
History
EC 4.2.3.130 created 2012
Orthology
K16188  tetraprenyl-beta-curcumene synthase
Genes
SAT: SYN_01806
RUE: DT065_08820 DT065_09020
BSU: BSU30500(ytpB)
BSR: I33_3107
BSL: A7A1_2184
BSH: BSU6051_30500(ytpB)
BSY: I653_14615
BSUT: BSUB_03240
BSUL: BSUA_03240(ytpB)
BSUS: Q433_16545
BSS: BSUW23_14790(ytpB)
BST: GYO_3302
BSO: BSNT_09473(ytpB)
BSX: C663_2898
BLI: BL00005(ytpB)
BLD: BLi03190(ytpB)
BLH: BaLi_c32610(ytpB)
BAY: RBAM_027520(ytpB)
BAQ: BACAU_2764(ytpB)
BYA: BANAU_2962(ytpB)
BAMP: B938_14195
BAML: BAM5036_2685(ytpB)
BAMA: RBAU_2887(ytpB)
BAMN: BASU_2693(ytpB)
BAMB: BAPNAU_2915(ytpB)
BAMT: AJ82_15600
BAMY: V529_30320
BMP: NG74_02890(ytpB)
BAO: BAMF_2833(ytpB)
BAZ: BAMTA208_14940(ytpB)
BQL: LL3_03129
BXH: BAXH7_03062(ytpB)
BQY: MUS_3335
BAMI: KSO_005315
BAMC: U471_28730
BAMF: U722_14850
BHA: BH3287
BAN: BA_5008
BAR: GBAA_5008
BAT: BAS4653
BAI: BAA_5021
BANT: A16_50060
BANR: A16R_50700
BANS: BAPAT_4807
BANV: DJ46_3669
BCE: BC4752
BCA: BCE_4903
BCQ: BCQ_4572
BCX: BCA_4881
BNC: BCN_4666
BCF: bcf_23875
BCER: BCK_11375
BTL: BALH_4333
BTT: HD73_5063
BTHI: BTK_24980
BTM: MC28_4044
BTG: BTB_c49110(ytpB)
BTI: BTG_25090
BTW: BF38_517
BWW: bwei_0134
BMYO: BG05_1281
BMYC: DJ92_1850
BCL: ABC1218
BPU: BPUM_2682
BPUM: BW16_14470
BPUS: UP12_13720
BMQ: BMQ_4856
BMD: BMD_4842
BMEG: BG04_1846
BAG: Bcoa_2422
BCOA: BF29_1136
BJS: MY9_3053
BMET: BMMGA3_13540(ytpB)
BACW: QR42_13545
BACP: SB24_14975
BACB: OY17_17060
BACY: QF06_13440
BACL: BS34A_33160(ytpB)
BALM: BsLM_3036
BEO: BEH_21675
BGY: BGLY_3594(ytpB)
BKW: BkAM31D_12285(ytpB_1) BkAM31D_19180(ytpB_2)
BBEV: BBEV_0732
GKA: GK2847
GTN: GTNG_2748
GGH: GHH_c29230(ytpB)
GEA: GARCT_02875(ytpB)
AFL: Aflv_0418
AAMY: GFC30_3138
AXL: AXY_08630
HHD: HBHAL_3850(ytpB)
VPN: A21D_02889(ytpB)
BSE: Bsel_1232
BBE: BBR47_09190(ytpB)
PPY: PPE_01699
PPM: PPSC2_08945(ytpB)
PPO: PPM_1702(ytpB)
PPOL: X809_09200
PPOY: RE92_03355
PMW: B2K_09645
PSAB: PSAB_09705
PRI: PRIO_2547(ytpB)
PSWU: SY83_20680
ASOC: CB4_02881(ytpB)
AAC: Aaci_0966
AAD: TC41_0976
JEO: JMA_25300
SWO: Swol_0969
SLP: Slip_1332
DSY: DSY2213
DHD: Dhaf_3343
DAU: Daud_1265
TMR: Tmar_0330
SAY: TPY_0399
CTHM: CFE_1287
MTA: Moth_0157
TOC: Toce_1521
PUF: UFO1_4742
PFT: JBW_04557
LPIL: LIP_1116
GLJ: GKIL_0406
 » show all
Taxonomy
Reference
1  [PMID:21627333]
  Authors
Sato T, Yoshida S, Hoshino H, Tanno M, Nakajima M, Hoshino T
  Title
Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-beta-curcumene synthase and a tetraprenyl-beta-curcumene cyclase: identification of a new terpene cyclase.
  Journal
J Am Chem Soc 133:9734-7 (2011)
DOI:10.1021/ja203779h
  Sequence
[bsu:BSU30500]
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.130
IUBMB Enzyme Nomenclature: 4.2.3.130
ExPASy - ENZYME nomenclature database: 4.2.3.130
BRENDA, the Enzyme Database: 4.2.3.130

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