KEGG   ENZYME: 4.2.3.41Help
Entry
EC 4.2.3.41                 Enzyme                                 

Name
elisabethatriene synthase;
elisabethatriene cyclase
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranylgeranyl-diphosphate diphosphate-lyase (elisabethatriene-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate = elisabethatriene + diphosphate [RN:R09685]
Reaction(KEGG)
Substrate
geranylgeranyl diphosphate [CPD:C00353]
Product
elisabethatriene [CPD:C19816];
diphosphate [CPD:C00013]
Comment
Requires Mg2+ or less efficiently Mn2+. The enzyme is also able to use farnesyl diphosphate and geranyl diphosphate.
History
EC 4.2.3.41 created 2009
Reference
1  [PMID:15019841]
  Authors
Kohl AC, Kerr RG
  Title
Identification and characterization of the pseudopterosin diterpene cyclase, elisabethatriene synthase, from the marine gorgonian, Pseudopterogorgia elisabethae.
  Journal
Arch Biochem Biophys 424:97-104 (2004)
DOI:10.1016/j.abb.2004.01.019
Reference
2  [PMID:16423548]
  Authors
Bruck TB, Kerr RG
  Title
Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae.
  Journal
Comp Biochem Physiol B Biochem Mol Biol 143:269-78 (2006)
DOI:10.1016/j.cbpb.2005.11.016
Other DBs
ExplorEnz - The Enzyme Database: 4.2.3.41
IUBMB Enzyme Nomenclature: 4.2.3.41
ExPASy - ENZYME nomenclature database: 4.2.3.41
BRENDA, the Enzyme Database: 4.2.3.41
CAS: 334022-59-2

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