KEGG ENZYME: 4.3.1.18

ENZYME: 4.3.1.18

Entry

EC 4.3.1.18 Enzyme

Name

D-serine ammonia-lyase;
D-hydroxyaminoacid dehydratase;
D-serine dehydrase;
D-hydroxy amino acid dehydratase;
D-serine hydrolase;
D-serine dehydratase (deaminating);
D-serine deaminase;
D-serine hydro-lyase (deaminating)

Class

Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases

Sysname

D-serine ammonia-lyase (pyruvate-forming)

Reaction(IUBMB)

D-serine = pyruvate + NH3 (overall reaction) [RN:R00221];
(1a) D-serine = 2-aminoprop-2-enoate + H2O;
(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous);
(1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous)

Reaction(KEGG)

R00221;
(other) R06131

Substrate

D-serine [CPD:C00740];
2-aminoprop-2-enoate [CPD:C02218];
2-iminopropanoate [CPD:C20904];
H2O [CPD:C00001]

Product

pyruvate [CPD:C00022];
NH3 [CPD:C00014];
2-aminoprop-2-enoate [CPD:C02218];
H2O [CPD:C00001];
2-iminopropanoate [CPD:C20904]

Comment

A pyridoxal-phosphate protein. The enzyme cleaves a carbon-oxygen bond, releasing a water molecule (hence the enzyme's original classification as EC 4.2.1.14, D-serine dehydratase) and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The latter reaction, which can occur spontaneously, can also be catalysed by EC 3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. Also acts, slowly, on D-threonine.

History

EC 4.3.1.18 created 1961 as EC 4.2.1.14, transferred 2001 to EC 4.3.1.18

Pathway

ec00260

Glycine, serine and threonine metabolism

Orthology

K01753

D-serine dehydratase

K20498

D-serine ammonia-lyase

Genes

SCE:	YGL196W(DSD1)

KLA:	KLLA0_F10813g

KMX:	KLMA_20223(DSD1)

LTH:	KLTH0A07986g KLTH0E03102g

ZRO:	ZYRO0G19404g

CGR:	CAGL0D01804g

NCS:	NCAS_0B05450(NCAS0B05450)

NDI:	NDAI_0B02730(NDAI0B02730)

PPA:	PAS_chr3_0186

DHA:	DEHA2G19492g

PIC:	PICST_35359 PICST_63574

PGU:	PGUG_03285

SPAA:

SPAPADRAFT_63627

CTP:	CTRG_05097

CTEN:

CANTEDRAFT_112230

YLI:	YALI0D15532g

CAUR:

QG37_03975

SLB:	AWJ20_34(DSD1) AWJ20_4453(DSD1)

FGR:	FGSG_12139

FPU:	FPSE_01951

FVR:	FVEG_09063

FOX:	FOXG_10900 FOXG_20295

NHE:	NECHADRAFT_100868 NECHADRAFT_56564

VAL:	VDBG_08911

VDA:	VDAG_06573

CFJ:	CFIO01_05050

PFY:	PFICI_10804

ANI:

AN7140.2

AFM:	AFUA_4G03722

ANG:	ANI_1_238124(An14g01470)

ACT:	ACLA_054730

NFI:	NFIA_029690

PCS:	Pc21g04310

NPA:	UCRNP2_6262

TML:	GSTUM_00011166001

SPO:	SPAC1039.06

CNE:

CNI00380

CNB:

CNBH0370

CGI:	CGB_H0760W

TMS:	TREMEDRAFT_68121

TVS:	TRAVEDRAFT_68383

DSQ:	DICSQDRAFT_95462

PCO:	PHACADRAFT_134256

SHS:	STEHIDRAFT_149030

HIR:	HETIRDRAFT_306271

PSQ:	PUNSTDRAFT_48709

ADL:	AURDEDRAFT_116588

FME:	FOMMEDRAFT_140172

GTR:	GLOTRDRAFT_53051

MRR:	Moror_17220

CCI:	CC1G_11234

SCM:	SCHCODRAFT_57407

ABP:	AGABI1DRAFT66972(AGABI1DRAFT_66972)

ABV:	AGABI2DRAFT197270(AGABI2DRAFT_197270)

CPUT:

CONPUDRAFT_91110

SLA:	SERLADRAFT_353974

PFP:	PFL1_03704

ECO:	b2366(dsdA)

ECJ:	JW2363(dsdA)

ECD:	ECDH10B_2531(dsdA)

EBW:	BWG_2134(dsdA)

ECOK:

ECMDS42_1923(dsdA)

ECE:	Z3628(dsdA)

ECS:

ECs3245

ECF:	ECH74115_3597(dsdA)

ETW:	ECSP_3315(dsdA)

ELX:	CDCO157_3009

EOJ:	ECO26_3426(dsdA)

EOH:	ECO103_2891(dsdA)

ECOO:

ECRM13514_3190(dsdA)

ECOH:

ECRM13516_3053(dsdA)

EOK:	G2583_2899(dsdA)

ESO:

O3O_18095

ESM:

O3M_07590

ESL:

O3K_07540

ECW:	EcE24377A_2652(dsdA)

ELH:

ETEC_2485

EUN:	UMNK88_2964(dsdA)

ECC:	c2901(dsdA)

ECP:	ECP_2391 ECP_4590

ECI:	UTI89_C2697(dsdA) UTI89_C4955

ECV:	APECO1_4170(dsdA)

ECX:	EcHS_A2503(dsdA)

ECM:	EcSMS35_2516(dsdA)

ECY:

ECSE_2663

ECR:	ECIAI1_2431(dsdA)

ECQ:	ECED1_2813(dsdA)

ECK:	EC55989_2659(dsdA)

ECT:	ECIAI39_2509(dsdA)

EOC:	CE10_2743(dsdA1) CE10_4258(dsdA2)

EUM:	ECUMN_2695(dsdA)

ECZ:	ECS88_2560(dsdA)

ELN:	NRG857_11890

ESE:

ECSF_2236

ECL:	EcolC_1303

EBR:	ECB_02276(dsdA)

EBD:

ECBD_1306

EKO:	EKO11_1352

EKF:	KO11_10930(dsdA)

EAB:	ECABU_c26860(dsdA)

EDH:	EcDH1_1291

EDJ:	ECDH1ME8569_2305(dsdA)

EIH:	ECOK1_2682(dsdA)

ENA:	ECNA114_2448(dsdA)

ELU:	UM146_04770 UM146_21995

ELW:	ECW_m2599(dsdA)

ELL:	WFL_12750(dsdA)

ELC:	i14_2699(dsdA)

ELD:	i02_2699(dsdA)

ELP:	P12B_c2483(dsdA)

EBL:	ECD_02276(dsdA)

EBE:	B21_02237(dsdA)

ELF:	LF82_0525(dsdA)

ECOA:

APECO78_15585

ECOL:

LY180_12185

ECOI:

ECOPMV1_02570(dsdA)

ECOJ:

P423_13160

ECOS:

EC958_2695

EFE:	EFER_3973(dsdA)

EAL:	EAKF1_ch3623c(dsdA)

STY:	STY3977(dsdA)

STT:	t3715(dsdA)

SEX:	STBHUCCB_39160

SENT:

TY21A_18830

STM:	STM3802(dsdA)

SEO:	STM14_4591(dsdA)

SEV:	STMMW_37931

SEY:	SL1344_3770(dsdA)

SEM:	STMDT12_C39610

SEJ:	STMUK_3790(dsdA)

SEB:	STM474_3977(dsdA)

SEF:	UMN798_4133(dsdA)

SETU:

STU288_19215

SETC:

CFSAN001921_21425

SENR:

STMDT2_36881(dsdA)

SEND:

DT104_37881(dsdA)

SENI:

CY43_19725

SEEN:

SE451236_01895

SPT:	SPA3653(dsdA)

SEK:

SSPA3411

SPQ:	SPAB_04730

SEI:	SPC_3885(dsdA)

SEC:	SCH_3724(dsdA)

SEH:	SeHA_C4132(dsdA)

SHB:

SU5_04280

SENH:

CFSAN002069_13015

SEEH:

SEEH1578_05165

SEE:	SNSL254_A4082(dsdA)

SENN:

SN31241_750

SEW:	SeSA_A4011(dsdA)

SEA:	SeAg_B4027(dsdA)

SENS:

Q786_18645

SED:	SeD_A4190(dsdA)

SEG:	SG3630(dsdA)

SEL:	SPUL_3766(dsdA)

SEGA:

SPUCDC_3752(dsdA)

SET:	SEN3619(dsdA)

SENA:

SENO:

SENV:

SENQ:

SENL:

SENJ:

SEEC:

SEEB:

SEEP:

SENB:

BN855_38940(dsdA)

SENE:

IA1_18490

SENC:

SEET0819_02840

SES:	SARI_03847

SFL:	SF2433(dsdA)

SFX:	S2570(dsdA)

SFV:	SFV_2425(dsdA)

SFE:	SFxv_2678(dsdA)

SFN:

SFy_3452

SFS:

SFyv_3527

SFT:	NCTC1_02669(dsdA)

SSN:	SSON_2457(dsdA)

SBO:	SBO_2392(dsdA)

SBC:	SbBS512_E2735(dsdA)

SDY:	SDY_2561(dsdA)

SDZ:	Asd1617_03446

SHQ:	A0259_15580

ENT:	Ent638_0021

ENC:

ECL_00023

ENO:	ECENHK_00350

ECLO:

ENC_03710

EEC:	EcWSU1_00025(dsdA)

ENL:	A3UG_00115

ECLG:

ECLE:

ECLN:

ECLI:

ECLX:

ECLY:

ECLZ:

EHM:	AB284_02365

EXF:	BFV63_00115

ECLA:

ECNIH3_00330

ECLC:

ECR091_00330

EAS:	Entas_0020

EAU:	DI57_18370

EKB:	BFV64_00115

ELG:	BH714_15315

ECAN:

CWI88_00090(dsdA)

ERN:	BFV67_00090

ECLS:

LI67_001000

ENR:	H650_14945

ENX:	NI40_000090

ENF:	AKI40_0017

KPN:	KPN_04081(dsdA)

KPU:	KP1_5458(dsdA)

KPM:	KPHS_52540

KPP:

A79E_0025

KPK:	A593_10610

KPH:	KPNIH24_26125

KPZ:	KPNIH27_25120

KPV:	KPNIH29_26075

KPW:	KPNIH30_26470

KPY:	KPNIH31_25545

KPG:	KPNIH32_27335

KPC:	KPNIH10_26095

KPQ:	KPR0928_25615

KPT:	VK055_3384(dsdA)

KPE:	KPK_0019(dsdA)

KPO:	KPN2242_23490

KPR:	KPR_0026(dsdA)

KPJ:

N559_0060

KPI:	D364_20865

KPA:	KPNJ1_00025

KPS:	KPNJ2_00025

KPX:	PMK1_01588(dsdA)

KPB:	FH42_16795

KPNE:

KU54_000125

KPNU:

LI86_00125

KPNK:

BN49_0026(dsdA)

KVA:

Kvar_0023

KVD:	KR75_08005

KVQ:	SP68_14600

KOX:

KOX_06460

KOE:

A225_5765

KOY:	J415_03280

KOM:	HR38_04960

KMI:	VW41_22810

KOK:	KONIH1_29055

KOC:	AB185_07435

KQU:	AVR78_04310

EAE:

EAE_06920

EAR:

CCG32623

KQV:	B8P98_00100(dsdA)

CKO:

CKO_00021

CRO:

ROD_40531

CFD:	CFNIH1_06530

CBRA:

A6J81_17370(dsdA)

CWE:	CO701_22240(dsdA)

CYO:	CD187_00090(dsdA)

CAMA:

F384_20105

CAF:	AL524_02910(dsdA)

CIF:	AL515_01185(dsdA)

CFAR:

CI104_00120(dsdA)

CIR:	C2U53_09580(dsdA)

CIE:	AN232_04535(dsdA)

GQU:	AWC35_18195

EBT:	EBL_c00590(dsdA)

ROR:	RORB6_18840

RON:	TE10_02105

RPLN:

B1209_00085

RAO:	DSD31_00110(dsdA)

CNT:	JT31_13160

CEN:	LH86_04490

ESC:	Entcl_0022

KLE:	AO703_02715 AO703_21365

KSA:	C813_15625

KOR:	AWR26_00095

KRD:	A3780_24585

KIN:	AB182_25395

LAX:	APT61_21990

LEI:	C2U54_04985(dsdA)

LEH:	C3F35_11490(dsdA)

LAZ:	A8A57_00335

LEF:	LJPFL01_0022

LNI:	CWR52_12395(dsdA)

LEW:	DAI21_04245(dsdA)

EBF:

D782_0024

EBC:	C2U52_08415(dsdA)

YEN:	YE0800(dsdA)

YEL:	LC20_04347

YEW:	CH47_2687(dsdA)

YEF:	FORC2_3298

YEE:	YE5303_25381(dsdA)

YAL:	AT01_3329(dsdA)

YIN:	CH53_875(dsdA)

YRO:	CH64_3415(dsdA)

YMA:	DA391_17905

SPE:

Spro_2515

SRR:	SerAS9_2499

SRL:	SOD_c23640(dsdA)

SRY:	M621_12915

SPLY:

Q5A_013070(dsdA)

SRS:	SerAS12_2500

SRA:	SerAS13_2501

SMAF:

D781_2212

SMW:	SMWW4_v1c24950(dsdA)

SMAR:

SM39_1940(dsdA)

SMAC:

SMDB11_1763(dsdA)

SLQ:	M495_12475

SERF:

L085_16215

SERS:

SERRSCBI_11780

SFW:	WN53_24890

SFG:	AV650_20530

SRZ:	AXX16_2929

SERM:

CLM71_11445

SFO:	Z042_24700

RAH:	Rahaq_0657

RAQ:	Rahaq2_0677

RAA:

Q7S_03015

ROX:	BV494_20150

DDA:	Dd703_3934

DDD:	Dda3937_01146(dsdA)

DZE:	Dd1591_4129

DDC:	Dd586_4103

DZC:	W909_19890

CED:	LH89_12930

DFN:	CVE23_21960

BGJ:	AWC36_02640

PAM:	PANA_3103(dsdA)

PLF:	PANA5342_0930(dsdA)

PAJ:	PAJ_2378(dsdA)

PAQ:	PAGR_g0932

PANT:

PSNIH1_p01555

PANP:

PSNIH2_12370

PSTW:

DSJ_04990

PGZ:	C2E15_06240

PCD:	C2E16_06160

TCI:	A7K98_18655

TPTY:

NCTC11468_03504(dsdA)

PLU:	plu1970(dsdA)

PLUM:

A4R40_09870

PAY:	PAU_02598(dsdA)

PTT:	VY86_21130

PMR:	PMI0187(dsdA)

PMIB:

BB2000_0346(dsdA)

PVL:	AOB99_03730

PVG:	CRN77_00290

PRG:	RB151_039390(dsdA)

PHEI:

NCTC12003_03480(dsdA)

MMK:

MU9_2605

ETR:	ETAE_0848(dsdA)

ETD:

ETAF_0792

ETE:	ETEE_2722(dsdA)

ETC:	ETAC_04065

EDW:	QY76_15960

EDL:	AAZ33_04495

EHO:	A9798_07240

HAV:	AT03_20905

OPO:	DSM2777_04520

PFQ:	QQ39_00500

LRI:	NCTC12151_03480(dsdA)

HSO:	HS_1718(dsdA)

HSM:

SACZ:

STEK:

PSUW:

LAB:	LA76x_0725

LAQ:	GLA29479_2934

LCP:	LC55x_4773

LGU:	LG3211_4570

LEZ:

GLE_4617

LEM:

LEN_0605

VCH:

VCA0875

VCF:	IR04_03815

VCS:

MS6_A0916

VCE:	Vch1786_II0563(dsdA)

VCQ:	EN18_02670

VCJ:	VCD_000458

VCI:

O3Y_17593

VCO:	VC0395_0362(dsdA)

VCR:	VC395_A0899(dsdA)

VCM:	VCM66_A0834(dsdA)

VCL:	VCLMA_B0646

VCX:	VAA049_2113(dsdA)

VCZ:	VAB027_314(dsdA)

VPA:

VP1248

VPB:

VPBB_1171

VPK:	M636_15565

VPF:	M634_08140

VPH:	VPUCM_1970

VHA:	VIBHAR_02609

VCA:	M892_00450

VAG:

N646_0285

VEX:	VEA_003747

VDB:	AL552_14485

VHR:	AL538_16380

VNA:	PN96_07340

VOW:	A9237_01670

VRO:	BSZ04_01270 BSZ04_14080

VSP:

VS_II0841

VEJ:	VEJY3_06025

VFU:	vfu_B00821

VNI:	VIBNI_A3115 VIBNI_B0503(dsdA)

VCY:	IX92_20760

VCT:	JV59_18855

VFL:	AL536_00725(dsdA)

VMI:	AL543_11285

VGA:	BSQ33_03750

AWD:	AWOD_II_0082

PPR:	PBPRB1408(S2570)

PAE:	PA3357(dsdA)

PAEV:

N297_3476(dsdA)

PAEI:

N296_3476(dsdA)

PAU:	PA14_20650(dsdA)

PAP:	PSPA7_1773(dsdA)

PAG:	PLES_17071(dsdA)

PAF:	PAM18_1608(dsdA)

PNC:	NCGM2_4488(dsdA)

PAEB:

NCGM1900_2918(dsdA)

PDK:	PADK2_07485

PSG:	G655_07975

PRP:	M062_17925

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

BN889_03728(dsdA)

PAEG:

AI22_25325

PAEC:

M802_3475(dsdA)

PAEO:

M801_3341(dsdA)

PMY:

Pmen_3266

PMK:

MDS_3558

PPSE:

BN5_1201(dsdA)

PCQ:	PcP3B5_31710

PPF:

Pput_3070

PPG:	PputGB1_3112

PPT:

PPS_3183

PPB:	PPUBIRD1_2990

PPI:

PPX:

PPUH:

PPUT:

PPUN:

PP4_31520(dsdA)

PPUD:

DW66_3454

PMON:

X969_15305

PMOT:

X970_14950

PPJ:	RK21_01455

PCH:	EY04_11015

PCZ:	PCL1606_37800

PCP:	JM49_18890

PFZ:	AV641_21840

PALK:

PSAKL28_20700

PSES:

PSCI_3625(dsdA) PSCI_4492

PSEM:

TO66_11860

PPSY:

AOC04_19230

ACB:

A1S_0973

ABY:	ABAYE2819(dsdA)

ABC:	ACICU_00935

ABN:

AB57_1052

ABX:

ABK1_0960

ABZ:	ABZJ_01077

ABR:	ABTJ_02837

ABD:	ABTW07_1064

ABH:

M3Q_1272

ABAD:

ABD1_09270(dsdA)

ABJ:	BJAB07104_01071

ABAB:

BJAB0715_01085

ABAJ:

BJAB0868_01085

ABAZ:

P795_12840

ABK:	LX00_04900

ABAU:

IX87_00660

ABAA:

IX88_06885

ABW:	BL01_11580

ABAL:

ABLAC_17420

ACC:	BDGL_000253(dsdA)

ANO:	RR32_13285

ALC:	OTEC02_14005

ACAL:

BUM88_04700

ACD:	AOLE_14470

ACI:	ACIAD1048(dsdA)

ATT:	AMQ28_03560

AHL:	AHTJS_07250

AJN:	BVL33_09155

ASOL:

BEN76_08455

ALA:	BFG52_08520

SPL:

Spea_3449

SHL:

Shal_3561

SPSW:

Sps_04143

CPS:	CPS_4659(dsdA)

COM:	CMT41_03025

PSEO:

OM33_20345

PPIS:

B1L02_21420

PSPO:

PSPO_b1264

PTU:	PTUN_a2403

PSEN:

PNC201_20365

LAL:	AT746_02095

FBL:

Fbal_1561

MVS:	MVIS_3608(dsdA)

MYA:	MORIYA_3844(dsdA)

CJA:	CJA_0345(dsd)

CEB:	B0D95_16755

CELL:

CBR65_17625

WOC:	BA177_03965 BA177_16555

HCH:	HCH_02978(dsdA)

HAK:	KO116_02815

HAF:	C8233_05295

CMAI:

BFX80_11465

MMW:	Mmwyl1_3826

MME:	Marme_3937

MARS:

A8C75_14285

AHA:	AHA_1438(dsdA)

AHY:	AHML_07775

AHD:	AI20_11945

AHR:	V428_08000

AHP:	V429_08005

AHJ:	V469_15495

AHH:	RY45_07580

AHI:	VU14_15325

ASA:	ASA_2940(dsdA)

AVR:

B565_1371

AVO:	AMS64_12850

AMED:

B224_1283

AAJ:	BOQ57_07015

ADH:	CK627_18960

AEM:	CK911_03680

AEA:	C2U39_15040(dsdA)

ARV:	C7N77_10490

OCE:	GU3_00765 GU3_13510

OCM:	CBP12_06975

OPF:	CBP31_11415

ZDF:	AN401_03765

GAP:	GAPWK_0797

VFF:	VITFI_CDS2864

VIT:	ADP71_13780

CVI:	CV_2648(dsdA)

CVC:	BKX93_03740

CHRO:

CXB49_11600(dsdA)

CHRI:

DK842_20200(dsdA)

PSE:

NH8B_3194

JEU:	BJP62_08275

RSO:	RSp1185(dsd)

RSL:	RPSI07_mp1215

RSN:	RSPO_m00835(dsd)

RSM:	CMR15_mp20288

RSE:

F504_4681

RPI:

Rpic_4197

RPF:	Rpic12D_4307

RPJ:	N234_27170 N234_27790

RMN:	TK49_21470

RIN:	ACS15_4121

REU:	Reut_A2915 Reut_B4022

REH:	H16_B1211(h16_B1211)

CNC:	CNE_1c31620(dsdA) CNE_2c11820

CUH:	BJN34_08390 BJN34_27700

RME:

Rmet_4770

CTI:	RALTA_B1122

CBW:	RR42_s1599 RR42_s1684

CGD:	CR3_1946(dsdA) CR3_3515(dsdA)

CCUP:

BKK81_29470 BKK81_30565

CUP:	BKK80_25790 BKK80_26885

CUU:	BKK79_31665 BKK79_32790

BMA:

BMA0176

BMV:	BMASAVP1_1576 BMASAVP1_1577 BMASAVP1_A2772

BML:	BMA10229_A2307

BMN:	BMA10247_2387

BMAL:

DM55_1580 DM55_3361 DM55_3362

BMAE:

DM78_413 DM78_4296 DM78_4297

BMAQ:

DM76_1559 DM76_4059 DM76_4060

BMAI:

DM57_2212

BMAF:

DM51_3151 DM51_4107 DM51_4108

BMAZ:

BM44_3321 BM44_3322 BM44_901

BMAB:

BM45_4159 BM45_4160 BM45_502

BPS:	BPSL0628 BPSS2116(dsdA)

BPM:	BURPS1710b_0834(dsd) BURPS1710b_A1220(dsdA)

BPL:	BURPS1106A_0672 BURPS1106A_A2856(dsdA)

BPD:	BURPS668_0656 BURPS668_A2980(dsdA)

BPR:	GBP346_A0584

BPSE:

BDL_1376 BDL_5579(dsdA)

BPSM:

BBQ_2799 BBQ_3996(dsdA)

BPSU:

BBN_2922 BBN_5601(dsdA)

BPSD:

BBX_3323 BBX_4746(dsdA)

BPZ:	BP1026B_I2897 BP1026B_II2277(dsdA)

BPQ:	BPC006_I0658 BPC006_II2817

BPK:	BBK_4883(dsdA) BBK_857

BPSH:

DR55_465 DR55_5614(dsdA)

BPSA:

BBU_1523 BBU_3880(dsdA)

BPSO:

X996_5395(dsdA) X996_72

BUT:	X994_2087 X994_4942(dsdA) X994_6500

BTE:	BTH_I0544 BTH_II0245(dsdA)

BTQ:	BTQ_3540(dsdA) BTQ_566

BTJ:	BTJ_1919 BTJ_4577(dsdA)

BTZ:	BTL_3155 BTL_5364(dsdA)

BTD:

BTI_3160

BTV:	BTHA_3438 BTHA_4836(dsdA)

BTHE:

BTN_1557 BTN_5035(dsdA)

BTHM:

BTRA_33 BTRA_5303(dsdA)

BTHA:

DR62_1744 DR62_5165

BTHL:

BG87_3348 BG87_5370(dsdA)

BOK:	DM82_3770(dsdA) DM82_56

BOC:	BG90_4273(dsdA) BG90_965

BVI:	Bcep1808_2847 Bcep1808_3327

BVE:	AK36_1155 AK36_3435(dsdA)

BUR:	Bcep18194_A6070 Bcep18194_B1364

BCN:

Bcen_2130

BCH:	Bcen2424_2742

BCM:	Bcenmc03_2768

BCJ:

BCEN:

BCEW:

BCEO:

BAM:

BAC:	BamMC406_2659

BMU:

Bmul_0557

BMJ:	BMULJ_02704(dsdA)

BMK:

DM80_2174

BMUL:

NP80_2875

BCT:	GEM_0700 GEM_3486

BCED:

DM42_2331

BCEP:

APZ15_01570 APZ15_30705

BDL:

AK34_347

BPYR:

ABD05_03740 ABD05_27525

BCON:

NL30_03835 NL30_26795

BUB:

BW23_2153

BDF:	WI26_13220

BLAT:

WK25_13285

BTEI:

WS51_24080

BSEM:

WJ12_13715 WJ12_28230

BPSL:

WS57_32455

BMEC:

WJ16_14060

BSTG:

WT74_14520

BSTL:

BBJ41_15065 BBJ41_21640

BGL:	bglu_1g30920

BGP:	BGL_1c32570

BGU:

KS03_546

BUG:	BC1001_0348

BGE:	BC1002_0359

BGF:	BC1003_0359

BGD:	bgla_1g34510

BGO:

BM43_945

BYI:	BYI23_A002850

BUK:	MYA_2500 MYA_2941

BUO:	BRPE64_ACDS02820

BUE:	BRPE67_ACDS02750

BUL:

BW21_3309

BUQ:	AC233_01975

BPLA:

bpln_1g31580

BUD:	AQ610_15830

BUZ:	AYM40_01920

BUM:	AXG89_07820

BXE:

Bxe_A4060

BXB:

DR64_1737

BPH:

Bphy_0364

BRH:	RBRH_02114

BPX:	BUPH_04241 BUPH_08485

BPY:	Bphyt_0639

BFN:

BCAI:

PSPW:

PARA:

PARB:

PHS:	C2L64_02040

PTER:

C2L65_01825

PGP:	CUJ91_02120

PPK:	U875_16155 U875_19815

PPNO:

DA70_08045 DA70_12500

PPNM:

LV28_18190 LV28_22535

PRB:	X636_14360 X636_18225

PPUL:

RO07_12485

PSPU:

NA29_08565

PAPI:

SG18_10470 SG18_12815

PVE:	UC34_04255

POX:	MB84_08695

PTX:	ABW99_13940

PFG:	AB870_15255

PNR:	AT302_12565

PLG:	NCTC10937_03056(dsdA)

BBH:	BN112_3092(ptpT)

BPT:	Bpet1585(dsd)

BAV:	BAV2693(dsd)

BHZ:	ACR54_01049

BTRM:

SAMEA390648701980(dsdA)

BBRO:

BAU06_13465 BAU06_19485

BFZ:	BAU07_06960 BAU07_20480

BPDZ:

BBN53_16545

BOH:	AKI39_18780

BGM:	CAL15_17710

AXY:	AXYL_01214 AXYL_01340(dsdA)

AXO:	NH44784_007801

AXN:	AX27061_1254

AXS:	LH59_05520

AXX:	ERS451415_01252

ADT:	APT56_05790 APT56_16785

AIS:	BUW96_13360 BUW96_19630 BUW96_20185

ASW:	CVS48_00205 CVS48_18515

ACHR:

C2U31_11445 C2U31_11995 C2U31_27465

AMIM:

MIM_c15400

CDN:	BN940_01716

AFA:	UZ73_18290

ODI:

ODI_R4060

OUR:	CEQ07_09865

RFR:

Rfer_0929

RSB:	RS694_06895

RHY:	RD110_13285

POL:

PNA:

AAV:

AJS:

DIA:	Dtpsy_1624

AAA:

Acav_2788

ACK:	C380_11220

ACRA:

BSY15_1148

VEI:

Veis_3329

DAC:

Daci_0845

DEL:	DelCs14_5686

DTS:	BI380_20465

DHK:	BO996_04295

VAP:	Vapar_1219

VPE:	Varpa_1301

VPD:	VAPA_1c12790

VAA:	AX767_14430

VBO:	CKY39_06485 CKY39_27895

VAM:	C4F17_13010

CTT:	CtCNB1_4379

CTES:

O987_25975

ADN:	Alide_2201

ADK:	Alide2_2390

LIM:	L103DPR2_01413

LIH:	L63ED372_00925

HYB:

Q5W_24600

DPY:	BA022_05980

SIMP:

C6571_07630

MELA:

C6568_12005

JAG:	GJA_1829(dsd)

JAZ:	YQ44_13460

JAL:	BZG29_14005

JSV:	CNX70_14520

HSE:	Hsero_1748(dsd)

HSZ:	ACP92_08710

HHT:	F506_13900

HRB:	Hrubri_1619(dsd)

HEE:	hmeg3_13890

CFU:	CFU_1273(dsd)

CARE:

LT85_3493

CPRA:

CPter91_3764

MNR:	ACZ75_18460

MASW:

MASZ:

MTIM:

MASY:

LCH:

RGE:

RBN:	RBXJA2T_13129

MIU:	ABE85_26315

RGU:	A4W93_07520

DMA:	DMR_17260(dsdA)

DRT:

Dret_1151

MLO:

mll6666

MAMO:

A6B35_23820

AMIH:

CO731_01655(dsdA)

SMI:	BN406_03694(dsd)

SMD:

Smed_2092

SIX:	BSY16_3238

SINO:

SS05631_b51120

RET:	RHE_PC00175

REC:	RHECIAT_CH0002054 RHECIAT_PC0000814

REL:	REMIM1_PB00191

REP:	IE4803_CH02015(dsdA) IE4803_PD00617

REI:	IE4771_CH02098(dsdA) IE4771_PE00632

RLE:

pRL100420

RLT:	Rleg2_1621

RLG:

Rleg_6379

RLB:	RLEG3_02005

RLU:	RLEG12_05700

RGA:	RGR602_PC00398

RHN:	AMJ98_PB00234

RPHA:

AMC79_CH02133(dsdA) AMC79_PA00274

RHX:	AMK02_PB00248

RHK:	Kim5_PD00590

NGL:	RG1141_PA10670

SHZ:	shn_19630 shn_26055

BJA:	bll3981(dsd)

BJU:	BJ6T_58500

BJP:	RN69_28355

MRD:	Mrad2831_0232

MOR:	MOC_0244(dsdA)

MPHY:

MCBMB27_05215

METX:

A3862_01120

MIV:	C4E04_11285

CHEL:

AL346_22240

DEQ:	XM25_05240

AUA:	M673_18510

CSE:

Cseg_3018

CMB:	CSW64_13590

RUE:	DT065_02580 DT065_07335

PAMI:

JCM7686_pAMI5p255

PGL:	PGA2_c23460(dsdA)

YAN:	AYJ57_23880

SPSE:

SULPSESMR1_04058(dsdA)

PABY:

Ga0080574_TMP88

NOV:	TQ38_020115

SMAG:

SMAZ:

SWI:

SPHD:

ADO:	A6F68_00098

ABS:	AZOBR_p310079(dsd)

ABQ:	ABAZ39_27335

ATI:	AL072_30145

AZT:	TSH58p_08330

NAO:	Y958_26420

BSU:	BSU23770(dsdA)

BSR:	I33_2452(dsdA)

BSL:

A7A1_3667

BSH:	BSU6051_23770(dsdA)

BSY:	I653_11385

BSUT:

BSUB_02550(dsdA)

BSUL:

BSUA_02550(dsdA)

BSUS:

Q433_12990

BSS:	BSUW23_11725(dsdA)

BST:	GYO_2620(dsdA)

BSO:	BSNT_08803(dsdA)

BSN:	BSn5_02405

BSQ:	B657_23770(dsdA)

BSX:	C663_2257(dsdA)

BSP:	U712_11580

BAY:	RBAM_021900(dsdA)

BAQ:	BACAU_2201(dsdA)

BYA:	BANAU_2342(dsdA)

BAMP:

B938_11320

BAML:

BAM5036_2114(dsdA)

BAMA:

RBAU_2327(dsdA)

BAMN:

BASU_2116(dsdA)

BAMB:

BAPNAU_1396(dsdA)

BAMT:

AJ82_12420

BAMY:

V529_24610(dsdA)

BMP:	NG74_02293(dsdA)

BAO:	BAMF_2274(dsdA)

BAZ:	BAMTA208_12175(dsdA)

BQL:	LL3_02563(dsdA)

BXH:	BAXH7_02484(dsdA)

BQY:	MUS_2629(dsdA)

BAMI:

KSO_008445

BAMC:

U471_22630

BAMF:

U722_11930

BVM:	B9C48_11135

BHA:	BH1762(dsdA)

BAN:	BA_1784(dsdA)

BAR:	GBAA_1784(dsdA)

BAT:

BAS1653

BAH:	BAMEG_2806(dsdA)

BAI:	BAA_1856(dsdA)

BAX:	H9401_1686

BANT:

BANR:

BANS:

BANH:

BANV:

DJ46_597(dsdA)

BCE:

BC1725

BCA:	BCE_1855(dsdA)

BCZ:	BCE33L1600(dsdA)

BCR:	BCAH187_A1907(dsdA)

BCB:	BCB4264_A1796(dsdA)

BCU:	BCAH820_1833(dsdA)

BCG:	BCG9842_B3545(dsdA)

BCQ:	BCQ_1792(dsdA)

BCX:	BCA_1793(dsdA)

BAL:	BACI_c17800(dsdA)

BNC:

BCF:

BCER:

BCEF:

BCY:	Bcer98_2017

BTK:	BT9727_1631(dsdA)

BTL:

BALH_1568

BTB:	BMB171_C1593(dsdA)

BTT:	HD73_1967 HD73_1968 HD73_3525

BTHR:

YBT1520_09795 YBT1520_17350

BTHI:

BTK_09965

BTC:	CT43_CH1661(dsdA)

BTF:	YBT020_09295 YBT020_09345

BTM:	MC28_0976(dsdA)

BTG:	BTB_c17740(dsdA)

BTI:

BTG_11805

BTN:	BTF1_06380

BTHT:

H175_ch1683

BTHU:

YBT1518_10005

BTW:	BF38_2953(dsdA)

BTHY:

AQ980_13665 AQ980_21145

BWE:	BcerKBAB4_1650

BWW:	bwei_3240(dsdA)

BMYO:

BG05_4193(dsdA)

BTY:	Btoyo_4356

BMYC:

DJ92_4320(dsdA)

BBY:	CY96_08105 CY96_29240

BCL:	ABC1954(dsdA)

BMQ:	BMQ_2083(dsdA)

BMD:	BMD_2040(dsdA)

BMH:	BMWSH_3178(dsdA)

BMEG:

BG04_4387(dsdA)

BJS:

MY9_2395

BLE:	BleG1_1112

BACP:

BACB:

BACO:

BACY:

BACL:

BS34A_26110(dsdA)

BALM:

BsLM_2330

BEO:

BEH_09495

BSJ:	UP17_12435

BON:	A361_16030

BFX:	BC359_08930 BC359_18755

BGI:	BGM20_05620

BKO:	CKF48_08205

BACS:

AUL54_18875

BMUR:

ABE28_012120

BIT:	BIS30_01580

OCN:	CUC15_08225

GKA:	GK1922(dsdA)

GTE:	GTCCBUS3UF5_22270

GTK:	GT3570_09105

GTM:	GT3921_09975

GLI:	GLN3_02755

GTN:

GTNG_1833

GYC:	GYMC61_2763

GYA:	GYMC52_1893

GCT:	GC56T3_1600

GGH:	GHH_c19860(dsdA)

GJF:	M493_09895

GEA:	GARCT_01893(dsdA)

GEL:	IB49_01480

GSE:	GT50_18845

GSR:	GS3922_07035

ANM:	GFC28_2156(dsdA)

AAMY:

GFC30_805(dsdA)

ANL:	GFC29_3280(dsdA)

LSP:

Bsph_2154

LGY:	T479_08430

LFU:	HR49_09170 HR49_15410

LYS:	LBYS11_07655

LYB:	C3943_09695

LYZ:	DCE79_06430

HHD:	HBHAL_1712(dsdA)

VIR:	X953_04400

VHL:	BME96_03600

VIL:	CFK37_15210

VNE:	CFK40_11480

LAO:	AOX59_04320

FAR:	ABE41_018345

SSP:

SSP0432

SXY:	BE24_09820

SXL:	SXYLSMQ121_0466

SXO:	SXYL_00469(dsdA)

SEQO:

SE1039_21340

SPET:

CEP67_06285

SSCU:

CEP64_01860

SNL:	BJD96_02530

SKL:	C7J89_03880

SHV:	AAT16_02995

BBE:	BBR47_25430(dsdA)

BFM:	BP422_07920

PLV:	ERIC2_c16230(dsdA)

PBJ:	VN24_07190 VN24_22460

ANX:	ACH33_09985

ASOC:

CB4_02061(dsdA)

SIV:

SSIL_2640

SSIL:

SOLI23_05420

SOB:	CSE16_06425 CSE16_07965

PLN:	Plano_1947

PKU:	AUO94_05970

PRT:	AUC31_17115

PLL:	I858_013095

PANA:

BBH88_09345

PDG:	BCM40_05500

PHC:	BBI08_06975

PMAR:

B0X71_01410

PPLA:

BBI15_05510

PFAE:

AJGP001_11575

PLX:	CW734_11510

KUR:	ASO14_1299(dsdA)

SPSY:

SPOR:

SPOP:

SURE:

SPOS:

RST:	ATY39_07100

LPL:	lp_2776(dsdA)

LPJ:	JDM1_2228(dsdA)

LPT:	zj316_2660(dsdA)

LPS:	LPST_C2282(dsdA)

LPR:	LBP_cg2273

LPZ:

Lp16_2189

LPB:	SH83_11690

LFE:

LAF_0744

LFR:

LC40_0503

LRA:	LRHK_2633(dsdA)

LBN:	LBUCD034_2355(dsdA)

LPX:	ASU28_11715

LOR:	AYI71_09065

LPAR:

FAM21731_01140

LPD:	AYR62_06300

LPG:	BB562_03875

PPE:

PEPE_1745

PPEN:

T256_08590

PCE:	PECL_124(dsdA)

PDM:	ADU72_1235

PIO:	PI20285_09290

EMU:

EMQU_2239

OOE:

OEOE_0657

WJO:	FOL01_1911

WPA:	CO680_08755

AUI:	APT62_04850

AVS:	AWM76_05385

AUH:	AWM75_07330

CRN:	CAR_c14010(dsdA1)

CAW:	Q783_06490

CARC:

NY10_1546 NY10_753

MARR:

BKP56_04445

JDA:	BW727_101612(dsdA)

CACE:

CACET_c11950(dsdA)

CCK:	Ccar_01660

AOE:

Clos_0664

GFE:	Gferi_23040

CLO:	HMPREF0868_0667(dsdA)

FPA:

LACY:

CSO:

CBOL:

CPRO:

CPRO_21900(dsdA)

EAC:	EAL2_808p01140(dsdA)

CST:	CLOST_0506(dsdA)

PBQ:	C3V37_03690

DSY:

DSY1743

DHD:

Dhaf_2895

DDH:	Desde_2343

DMT:	DESME_06710

DRM:

Dred_0329

DCA:	Desca_1375

DOR:	Desor_2835

DMI:	Desmer_2239

ELM:

ELI_0671

OVA:	OBV_29670(dadA)

EUU:	ADJ67_07240

BPRM:

CL3_33400

CHY:	CHY_0067(dsdA)

TEP:	TepRe1_0952

TAE:	TepiRe1_1042(dsdA)

MEG:	DKB62_06230

SELE:

ADJ74_04340

PFT:

JBW_00837

CPO:	COPRO5265_1590

CUR:	cu1755(dsdA)

CUA:	CU7111_1692(dsdA)

CMD:	B841_07640

CVT:	B843_06255

CGY:	CGLY_02450(dsdA)

CMQ:	B840_07295(dsdA)

CFK:	CFRA_09190

CFC:	CFLV_03295

KRH:	KRH_22290(dsdA)

DVA:	DAD186_04340

BLY:	A2T55_00310

BLIN:

BLSMQ_3772

DCO:	SAMEA4475696_1531(dsdA)

PPC:	HMPREF9154_0768(dsdA)

AMQ:	AMETH_0365

ASG:	FB03_05385

BACT:

AB656_05545

TPI:	TREPR_0461(dsdA)

BRM:

Bmur_0789

ACA:

ACP_0035

GMA:	AciX8_2261

ABAS:

ACPOL_3509

FNU:

FN0553

FNT:	HMPREF0405_01163

FUS:	HMPREF0409_02317

FNE:	FSDG_00997

FVA:	FV113G1_12790(dsdA)

FUL:	C4N20_12220(dsdA)

FMO:	C4N19_00730

ASL:	Aeqsu_0722

DTN:	DTL3_0505(dsdA)

» show all

Reference

1 [PMID:5327100]

Authors

Dupourque D, Newton WA, Snell EE.

Title

Purification and properties of D-serine dehydrase from Escherichia coli.

Journal

J Biol Chem 241:1233-8 (1966)

Reference

2 [PMID:12999751]

Authors

METZLER DE, SNELL EE.

Title

Deamination of serine. II. D-Serine dehydrase, a vitamin B6 enzyme from Escherichia coli.

Journal

J Biol Chem 198:363-73 (1952)

Other DBs

ExplorEnz - The Enzyme Database:

4.3.1.18

IUBMB Enzyme Nomenclature:

4.3.1.18

ExPASy - ENZYME nomenclature database:

4.3.1.18

BRENDA, the Enzyme Database:

4.3.1.18

CAS:

9015-88-7

DBGET integrated database retrieval system