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Entry
EC 4.3.1.2                  Enzyme                                 

Name
methylaspartate ammonia-lyase;
beta-methylaspartase;
3-methylaspartase;
L-threo-3-methylaspartate ammonia-lyase
Class
Lyases;
Carbon-nitrogen lyases;
Ammonia-lyases
BRITE hierarchy
Sysname
L-threo-3-methylaspartate ammonia-lyase (mesaconate-forming)
Reaction(IUBMB)
L-threo-3-methylaspartate = mesaconate + NH3 [RN:R03696]
Reaction(KEGG)
Substrate
L-threo-3-methylaspartate [CPD:C03618]
Product
mesaconate [CPD:C01732];
NH3 [CPD:C00014]
Comment
A cobalamin protein.
History
EC 4.3.1.2 created 1961
Pathway
ec00630  Glyoxylate and dicarboxylate metabolism
ec00660  C5-Branched dibasic acid metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K04835  methylaspartate ammonia-lyase
Genes
AFM: AFUA_3G00790
AOR: AO090010000710
AFV: AFLA_122010
NFI: NFIA_001410
PDP: PDIP_33520
ECE: Z0892
ECS: ECs0761
ECF: ECH74115_0829
ETW: ECSP_0779
ELX: CDCO157_0741
EOC: CE10_0730
EFE: EFER_2378
SDY: SDY_0673
KOX: KOX_14665
KOE: A225_1756
CKO: CKO_02419
CAMA: F384_03285
YEN: YE4043
YEY: Y11_31521
YEW: CH47_3688
YET: CH48_1495
YAL: AT01_1098
YIN: CH53_313
YRO: CH64_1340
MMK: MU9_1023
PPUL: RO07_15990
BPER: BN118_0709
MLO: mlr6095
CTC: CTC_02563
CSQ: CSCA_4328
AMT: Amet_3414
DSY: DSY3233
DHD: Dhaf_4400
DRM: Dred_2689
CTHM: CFE_0619
PUF: UFO1_3073
PFT: JBW_01516
MMAR: MODMU_4014
KAL: KALB_5717
TDE: TDE2235
TPED: TPE_1176
DTU: Dtur_1344
HAL: VNG_2289G(mal)
HSL: OE_4207F(mal)
HMA: rrnAC0687(mal)
HHI: HAH_1339(mal)
HMU: Hmuk_2982
HTU: Htur_1592
NMG: Nmag_3336(mal)
NAT: NJ7G_3291
SALI: L593_04670
 » show all
Taxonomy
Reference
1  [PMID:13618029]
  Authors
BARKER HA, SMYTH RD, WAWSZKIEWICZ EJ, LEE MN, WILSON RM.
  Title
Enzymic preparation and characterization of an alpha-L-beta-methylaspartic acid.
  Journal
Arch Biochem Biophys 78:468-76 (1958)
DOI:10.1016/0003-9861(58)90371-0
Reference
2
  Authors
Bright, H.J. and Ingraham, L.L.
  Title
The preparation of crystalline beta-methylaspartase.
  Journal
Biochim Biophys Acta 44:586-588 (1960)
Other DBs
ExplorEnz - The Enzyme Database: 4.3.1.2
IUBMB Enzyme Nomenclature: 4.3.1.2
ExPASy - ENZYME nomenclature database: 4.3.1.2
BRENDA, the Enzyme Database: 4.3.1.2
CAS: 9033-26-5

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