KEGG   ENZYME: 4.3.3.6Help
Entry
EC 4.3.3.6                  Enzyme                                 

Name
pyridoxal 5'-phosphate synthase (glutamine hydrolysing);
PdxST
Class
Lyases;
Carbon-nitrogen lyases;
Amine-lyases
BRITE hierarchy
Sysname
D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5'-phosphate-lyase
Reaction(IUBMB)
D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate (overall reaction) [RN:R10089];
(1a) L-glutamine + H2O = L-glutamate + NH3 [RN:R00256];
(1b) D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate [RN:R10088]
Reaction(KEGG)
Substrate
D-ribose 5-phosphate [CPD:C00117];
D-glyceraldehyde 3-phosphate [CPD:C00118];
L-glutamine [CPD:C00064];
H2O [CPD:C00001];
NH3 [CPD:C00014]
Product
pyridoxal 5'-phosphate [CPD:C00018];
L-glutamate [CPD:C00025];
H2O [CPD:C00001];
phosphate [CPD:C00009];
NH3 [CPD:C00014]
Comment
The ammonia is provided by the glutaminase subunit and channeled to the active site of the lyase subunit by a 100 A tunnel. The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate. The enzyme complex is found in aerobic bacteria, archaea, fungi and plants.
History
EC 4.3.3.6 created 2011
Pathway
ec00750  Vitamin B6 metabolism
Orthology
K06215  pyridoxal 5'-phosphate synthase pdxS subunit
K08681  5'-phosphate synthase pdxT subunit
Genes
RSS: 109442040 109442118
CIN: 100176842 100179166
LGI: LOTGIDRAFT_116826 LOTGIDRAFT_232087
CRG: 105317985 105318005
MYI: 110441274 110441275 110444099
OBI: 106876231 106881397
LAK: 106181317
NVE: NEMVE_v1g175375 NEMVE_v1g194582
EPA: 110247081 110247087
ADF: 107341663 107341923
ATH: AT2G38230(PDX1.1) AT3G16050(PDX1.2) AT5G01410(RSR4) AT5G60540(PDX2)
LJA: Lj0g3v0021599.1(Lj0g3v0021599.1) Lj0g3v0021599.2(Lj0g3v0021599.2) Lj3g3v2284470.1(Lj3g3v2284470.1) Lj3g3v2286550.1(Lj3g3v2286550.1) Lj6g3v1967070.1(Lj6g3v1967070.1)
DOSA: Os02t0130100-01(Os02g0130100) Os07t0100200-01(Os07g0100200) Os10t0100700-01(Os10g0100700) Os10t0191600-00(Os10g0191600) Os11t0708500-01(Os11g0708500)
ATS: 109731717(LOC109731717) 109757789(LOC109757789) 109766728(LOC109766728) 109771478(LOC109771478)
ZMA: 100272732 100280630 100280887(AY109859)
SCE: YFL059W(SNZ3) YFL060C(SNO3) YMR095C(SNO1) YMR096W(SNZ1) YNL333W(SNZ2) YNL334C(SNO2)
KMX: KLMA_30724(SNZ3) KLMA_30726(SNO3)
NCS: NCAS_0H03630(NCAS0H03630) NCAS_0H03640(NCAS0H03640)
TPF: TPHA_0G03060(TPHA0G03060) TPHA_0G03070(TPHA0G03070)
TDL: TDEL_0A02410(TDEL0A02410) TDEL_0A02420(TDEL0A02420)
SLB: AWJ20_5148(SNZ1)
NCR: NCU06549(pdx-2) NCU06550(pdx-1)
NTE: NEUTE1DRAFT116296(NEUTE1DRAFT_116296) NEUTE1DRAFT128413(NEUTE1DRAFT_128413)
ANG: ANI_1_1718104(An12g03940) ANI_1_504034(An03g04280)
ABP: AGABI1DRAFT111385(AGABI1DRAFT_111385) AGABI1DRAFT63730(AGABI1DRAFT_63730)
ABV: AGABI2DRAFT190607(AGABI2DRAFT_190607) AGABI2DRAFT230018(AGABI2DRAFT_230018)
PYO: PY17X_0933800(PY02155) PY17X_1121500(PY04475)
PCB: PCHAS_091250(PC000116.05.0) PCHAS_111970(PC000552.03.0)
SMIN: v1.2.024463.t1(symbB.v1.2.024463.t1)
NGD: NGA_0217100(PDXT)
HIE: R2846_0744(pdxT) R2846_0745(pdxS)
HIZ: R2866_0806(pdxT) R2866_0807(pdxS)
HIK: HifGL_000922(pdxT) HifGL_000923(pdxS)
HIW: NTHI477_00434(pdxS) NTHI477_00435(pdxT)
HIC: NTHIC486_01439(pdxS) NTHIC486_01440(pdxT)
HIX: NTHI723_00344(pdxS) NTHI723_00345(pdxT)
PMV: PMCN06_2230(pdxT) PMCN06_2231(pdxS)
PMP: Pmu_21510(pdxT) Pmu_21520(pdxS)
PMUL: DR93_733(pdxT) DR93_734
MHX: MHH_c03050(pdxS) MHH_c03060(pdxT)
APL: APL_0572(pdxS) APL_0573(pdxT)
APA: APP7_0616(pdxS) APP7_0617(pdxT)
FTQ: RO31_0580 RO31_0581(pdxT)
FTC: DA46_1203 DA46_1204(pdxT)
FTV: CH67_1944(pdxT) CH67_1945
FTZ: CH68_1674(pdxT) CH68_1675
FTX: AW25_1426(pdxT) AW25_1427
FTD: AS84_74(pdxT) AS84_75
FTY: CH70_1456(pdxT) CH70_1457
FPT: BZ13_1835 BZ13_1836(pdxT)
FPI: BF30_414(pdxT) BF30_415
FPM: LA56_77 LA56_78(pdxT)
FPX: KU46_1137 KU46_1138(pdxT)
FPZ: LA55_612 LA55_613(pdxT)
FPJ: LA02_1849(pdxT) LA02_1850
CURE: CUREO_0372(pdxS)
CSPF: CSF_1574(pdxS)
DTR: RSDT_0086(pdxS) RSDT_0087(pdxT)
DML: Dmul_28090(pdxT) Dmul_28100(pdxS)
AMV: ACMV_P3_00450(pdxS) ACMV_P3_00460(pdxT)
BSU: BSU00110(yaaD) BSU00120(yaaE)
BSH: BSU6051_00110(pdxS) BSU6051_00120(pdxT)
BSUT: BSUB_00016(pdxS) BSUB_00017(pdxT)
BSUL: BSUA_00016(pdxS) BSUA_00017(pdxT)
BSS: BSUW23_00060(pdxS) BSUW23_00065(pdxT)
BSO: BSNT_06300(yaaD) BSNT_06301(yaaE)
BSQ: B657_00110(pdxS) B657_00120(pdxT)
BSX: C663_0013 C663_0014(pdxT)
BLI: BL02353(pdxS) BL02354(pdxT)
BLD: BLi00016(pdxS) BLi00017(pdxT)
BLH: BaLi_c00160(pdxS) BaLi_c00170(pdxT)
BAY: RBAM_000140(pdxS) RBAM_000150(pdxT)
BAQ: BACAU_0011(pdxS) BACAU_0012(pdxT)
BYA: BANAU_0011(pdxS) BANAU_0012(pdxT)
BAML: BAM5036_0012(pdxS) BAM5036_0013(pdxT)
BAMA: RBAU_0013(pdxS) RBAU_0014(pdxT)
BAMN: BASU_0013(pdxS) BASU_0014(pdxT)
BAMB: BAPNAU_0011(pdxS) BAPNAU_0012(pdxT)
BAMY: V529_00110(pdxS) V529_00120(pdxT)
BMP: NG74_00016(pdxS) NG74_00017(pdxT)
BAO: BAMF_0011(pdxS) BAMF_0012(pdxT)
BAZ: BAMTA208_00050(pdxS) BAMTA208_00055(pdxT)
BQL: LL3_00011(pdxS) LL3_00012(pdxT)
BXH: BAXH7_00011(pdxS) BAXH7_00012(pdxT)
BQY: MUS_0013(pdxS) MUS_0014(pdxT)
BAN: BA_0010 BA_0011(pdxT)
BANV: DJ46_4402 DJ46_4403(pdxT)
BCZ: BCE33L0011(pdx1) BCE33L0012(guaA)
BCQ: BCQ_0016(pdx1) BCQ_0017(guaA)
BAL: BACI_c00150(pdx1) BACI_c00160(guaA1)
BTK: BT9727_0011(pdx1) BT9727_0012(guaA)
BTL: BALH_0011(pdxA) BALH_0012(pdxT)
BTM: MC28_4730(pdxS) MC28_4731(pdxT)
BTG: BTB_c00150(pdxS) BTB_c00160(pdxT)
BTW: BF38_1227 BF38_1228(pdxT)
BWW: bwei_5817(pdxS) bwei_5818(pdxT)
BMYO: BG05_498(pdxT) BG05_499
BMYC: DJ92_2599 DJ92_2600(pdxT)
BPF: BpOF4_08010(pdxS) BpOF4_08015(pdxT)
BMQ: BMQ_0015(pdxS) BMQ_0016(pdxT) BMQ_2366
BMD: BMD_0015(pdxS) BMD_0016(pdxT) BMD_2328
BMH: BMWSH_2868 BMWSH_4971(pdxT) BMWSH_4972(pdxS)
BCOA: BF29_2362 BF29_2363(pdxT)
BMET: BMMGA3_00080(pdxS) BMMGA3_00085(pdxT)
BACO: OXB_0984
BACL: BS34A_00170(yaaD) BS34A_00180(yaaE)
BGY: BGLY_0010(pdxS) BGLY_0011(pdxT)
BKW: BkAM31D_00075(pdxS_1) BkAM31D_00080(pdxT) BkAM31D_19445(pdxS_2)
BBEV: BBEV_3368(pdxT) BBEV_3369(pdxS)
GGH: GHH_c00160(pdxS) GHH_c00170(pdxT)
GEA: GARCT_00016(pdxS) GARCT_00017(pdxT)
AFL: Aflv_0011(pdxS) Aflv_0012(pdxT)
AAMY: GFC30_187(pdxT) GFC30_188
AXL: AXY_00110(pdxS)
LSP: Bsph_0021 Bsph_0022(pdxT)
VPN: A21D_01459(pdxT) A21D_01460(pdxS)
SUZ: MS7_0508 MS7_0509(pdxT)
SAUT: SAI1T1_2003960(pdxS) SAI1T1_2003970(pdxT)
SAUJ: SAI2T2_1003960(pdxS) SAI2T2_1003970(pdxT)
SAUK: SAI3T3_1003960(pdxS) SAI3T3_1003970(pdxT)
SAUQ: SAI4T8_1003960(pdxS) SAI4T8_1003970(pdxT)
SAUV: SAI7S6_1003950(pdxS) SAI7S6_1003960(pdxT)
SAUW: SAI5S5_1003930(pdxS) SAI5S5_1003940(pdxT)
SAUX: SAI6T6_1003940(pdxS) SAI6T6_1003950(pdxT)
SAUY: SAI8T7_1003950(pdxS) SAI8T7_1003960(pdxT)
SAUF: X998_0559 X998_0560(pdxT)
SAUC: CA347_534 CA347_535(pdxT)
SAUR: SABB_00569(pdxS) SABB_00570(pdxT)
SEPS: DP17_1592 DP17_1593(pdxT)
SCA: SCA_0173(pdx1) SCA_0174
SDT: SPSE_2277(pdxT) SPSE_2278(pdxS)
SXO: SXYL_02401(pdxT) SXYL_02402(pdxS)
SHU: SHYC_11050(pdxT) SHYC_11055(pdxS)
SCAP: AYP1020_2267(pdxS) AYP1020_2268(pdxT)
MCAK: MCCS_24440(pdxT) MCCS_24450(pdxS)
LMOQ: LM6179_2872(pdxS) LM6179_2873(pdxT)
LMR: LMR479A_2212(pdxS) LMR479A_2213(pdxT)
LMOG: BN389_21310(pdxS) BN389_21320(pdxT)
LMQ: LMM7_2200(pdxS) LMM7_2201(pdxT)
LWE: lwe2122(yaaD) lwe2123
EAN: Eab7_0011(pdxS) Eab7_0012(pdxT)
BBE: BBR47_00160(pdxS) BBR47_00170(pdxT)
PPM: PPSC2_00450(yaaD) PPSC2_00455(guaA1)
PPO: PPM_0082(yaaD) PPM_0083(guaA1)
PPQ: PPSQR21_000900(sNZ1) PPSQR21_000910(pDX2)
PMS: KNP414_00014(pdxS) KNP414_00015(pdxT) KNP414_00680(pdxS2) KNP414_06898(pdxS3) KNP414_07445(pdxS4)
PLV: ERIC2_c00140(pdxS) ERIC2_c00150(pdxT)
PRI: PRIO_0083(pdxS) PRIO_0084(pdxT)
ASOC: CB4_00371(pdxT) CB4_00372(pdxS)
AAD: TC41_0015(pdxS) TC41_0016(pdxT)
SPR: spr1321 spr1322(pdx1)
SPW: SPCG_1456 SPCG_1457(pdx1)
SPX: SPG_1393(pdxT) SPG_1394(pdxS)
SGT: SGGB_1182(pdxT) SGGB_1183(pdxS)
SMB: smi_1388 smi_1389(pdx1)
SSR: SALIVB_0652(pdxS) SALIVB_0653(pdxT)
STF: Ssal_00730(pdxS) Ssal_00731(pdxT)
STJ: SALIVA_1438(pdxT) SALIVA_1439(pdxS)
SMN: SMA_1104(pdxT) SMA_1105
SIF: Sinf_1021 Sinf_1022(pdxS)
SLU: KE3_1091
STRN: SNAG_1312(pdxT) SNAG_1313(pdxS)
CML: BN424_2277(pdxT) BN424_2278(pdxS)
CAE: SMB_G0608 SMB_G0609(pdxT)
CBO: CBO2800(pyroA)
CBA: CLB_2743
CBH: CLC_2676
CBL: CLK_2186(pdxT) CLK_2187
CBB: CLD_1774
CBF: CLI_2850
CBM: CBF_2842
CKL: CKL_2414(pdxT) CKL_2415(pdxS)
CSR: Cspa_c57560(pdxT) Cspa_c57570(pdxS)
CPAT: CLPA_c17360(pdxS) CLPA_c17370(pdxT)
CPAE: CPAST_c17360(pdxS) CPAST_c17370(pdxT)
CSB: CLSA_c44900(pdxT) CLSA_c44910(pdxS)
CBV: U729_17(pdxT) U729_18
CLD: CLSPO_c28740(pdxT) CLSPO_c28750(pdxS)
CTYK: CTK_C21790(pdxS) CTK_C21800(pdxT)
ASM: MOUSESFB_0742(pdxT) MOUSESFB_0743(pdxS)
ASO: SFBmNL_00875(pdxT) SFBmNL_00876(pdxS)
ASB: RATSFB_0664(pdxT) RATSFB_0665(pdxS)
HSC: HVS_06425(pdxS)
CCEL: CCDG5_1245(pdxS) CCDG5_1246(pdxT)
RIM: ROI_06940
EAC: EAL2_808p06340(pdxT) EAL2_808p06350(pdxS)
CST: CLOST_0100(pdxT) CLOST_0101(pdxS)
SWO: Swol_0007
PTH: PTH_0009(SNZ1) PTH_0010(PDX2)
DED: DHBDCA_p1741 DHBDCA_p7(pdxS) DHBDCA_p8(pdxT)
DEC: DCF50_p1750 DCF50_p7(pdxS) DCF50_p8(pdxT)
HMO: HM1_0854(pdxT) HM1_0855
ELM: ELI_4582
AWO: Awo_c05240(pdxT) Awo_c05250(pdxS)
SAY: TPY_0008(pdxS) TPY_0009(pdxT)
TTE: TTE0822(Pdx2) TTE0823(Snz1)
TKI: TKV_c07130(pdxS) TKV_c07140(pdxT)
TAE: TepiRe1_2728(pdxS)
TPZ: Tph_c00140(pdxS) Tph_c00150(pdxT)
TOC: Toce_2206
FMA: FMG_1460
APR: Apre_0049
PMIC: NW74_05355
CAD: Curi_c17780(pdxS)
SRI: SELR_00890(pdxS) SELR_00900(pdxT)
MTU: Rv2604c(snoP) Rv2606c(snzP)
MBO: BQ2027_MB2636C(snop) BQ2027_MB2638C(snzp)
MBM: BCGMEX_2622c(pdxT) BCGMEX_2624c(pdxS)
MCQ: BN44_60067(snoP) BN44_60069(snzP)
MCV: BN43_40281(snoP) BN43_40283(snzP)
MCX: BN42_40589(snoP) BN42_40591(snzP)
MCZ: BN45_50996(snoP) BN45_50998(snzP)
MUL: MUL_3248(snoP) MUL_3250(snzP)
MMI: MMAR_2094(snzP) MMAR_2096(snoP)
MMAE: MMARE11_20370(snzP) MMARE11_20390(snoP)
MLI: MULP_03057(snoP) MULP_03059(snzP)
MSG: MSMEI_2863(pdxS) MSMEI_2865(pdxT)
MPHL: MPHLCCUG_03035(pdxT) MPHLCCUG_03037(pdxS)
MTHN: 4412656_02659(pdxT) 4412656_02661(pdxS)
MSTE: MSTE_02853(pdxT) MSTE_02855(pdxS)
MJD: JDM601_2386(snoP) JDM601_2388(snzP)
MTER: 4434518_02315(snoP) 4434518_02317(pdxS)
CGL: NCgl0754(Cgl0788) NCgl0755(Cgl0789)
CGM: cgp_0898(pdxS) cgp_0899(pdxT)
CEF: CE1779
CDP: CD241_0181(pdxS) CD241_0182(pdxT)
CDH: CDB402_0149(pdxS) CDB402_0150(pdxT)
CDT: CDHC01_0183(pdxS) CDHC01_0184(pdxT)
CDE: CDHC02_0187(pdxS) CDHC02_0188(pdxT)
CDR: CDHC03_0155(pdxS) CDHC03_0156(pdxT)
CDA: CDHC04_0140(pdxS) CDHC04_0141(pdxT)
CDZ: CD31A_0224(pdxS) CD31A_0225(pdxT)
CDB: CDBH8_0184(pdxS) CDBH8_0185(pdxT)
CDS: CDC7B_0181(pdxS) CDC7B_0182(pdxT)
CDD: CDCE8392_0182(pdxS) CDCE8392_0183(pdxT)
CDW: CDPW8_0223(pdxS) CDPW8_0224(pdxT)
CDV: CDVA01_0137(pdxS) CDVA01_0138(pdxT)
CDIP: ERS451417_00152(pdxS) ERS451417_00153(pdxT)
CUR: cu0931
CUA: CU7111_0917(pdxS)
CAR: cauri_0520(pdxS) cauri_0521(pdxT)
CKP: ckrop_1033(pdxT) ckrop_1034(pdxS)
CPU: cpfrc_00132(pdxS) cpfrc_00133(pdxT)
CPL: Cp3995_0131(pdxS) Cp3995_0132(pdxT)
CPG: Cp316_0143(pdxS) Cp316_0144(pdxT)
CPP: CpP54B96_0134(pdxS) CpP54B96_0135(pdxT)
CPK: Cp1002_0128(pdxS) Cp1002_0129(pdxT)
CPQ: CpC231_0131(pdxS) CpC231_0132(pdxT)
CPX: CpI19_0131(pdxS) CpI19_0132(pdxT)
CPZ: CpPAT10_0130(pdxS) CpPAT10_0131(pdxT)
COR: Cp267_0138(pdxS) Cp267_0139(pdxT)
COP: Cp31_0144(pdxS) Cp31_0145(pdxT)
COD: Cp106_0131(pdxS) Cp106_0132(pdxT)
COS: Cp4202_0127(pdxS) Cp4202_0128(pdxT)
COI: CpCIP5297_0139(pdxS) CpCIP5297_0140(pdxT)
COE: Cp258_0141(pdxS) Cp258_0142(pdxT)
COU: Cp162_0134(pdxS) Cp162_0135(pdxT)
CRD: CRES_1139(pdxT) CRES_1141(pdxS)
CUL: CULC22_00178(pdxS) CULC22_00179(pdxT)
CUC: CULC809_00181(pdxS) CULC809_00182(pdxT)
CUE: CULC0102_0217(pdxS) CULC0102_0218(pdxT)
CUN: Cul210932_0189(pdxS) Cul210932_0190(pdxT)
CUS: CulFRC11_0178(pdxS) CulFRC11_0179(pdxT)
CUQ: Cul210931_0184(pdxS) Cul210931_0185(pdxT)
CUZ: Cul05146_0196(pdxS) Cul05146_0197(pdxT)
CUJ: CUL131002_0175(pdxS) CUL131002_0176(pdxT)
CVA: CVAR_1551(pdxT) CVAR_1553(pdxS)
CGY: CGLY_08125(pdxS) CGLY_08135(pdxT)
COA: DR71_2133 DR71_2135(pdxT)
CSX: CSING_02895(pdxS) CSING_02900(pdxT)
CMQ: B840_09720(pdxS) B840_09725(pdxT)
CKU: UL82_03260(pdxS) UL82_03265(pdxT)
CMV: CMUST_00115(pdxS)
CEI: CEPID_07115(pdxT) CEPID_07130(pdxS)
CTED: CTEST_07465(pdxS)
CDX: CDES_03985(pdxS) CDES_03990(pdxT)
CSP: WM42_0845(pdxT) WM42_0846
CGV: CGLAU_06390(pdxS)
CAMG: CAMM_01255
CMIN: NCTC10288_02024(pdxT) NCTC10288_02025(pdxS)
NCY: NOCYR_3601(pdxT) NOCYR_3604(pdxS)
NNO: NONO_c46090(pdxT) NONO_c46150(pdxS)
NSR: NS506_03894(pdxS) NS506_03910(pdxT)
RER: RER_29090(pdx1) RER_29150(pdx2)
ROP: ROP_68630(pdx1) ROP_68670(pdx2)
RFA: A3L23_04416(pdxT) A3L23_04419(pdxS)
RHS: A3Q41_03848(pdxS) A3Q41_03851(pdxT)
RHU: A3Q40_01568(pdxS) A3Q40_01571(pdxT)
RRT: 4535765_02119(pdxS) 4535765_02123(pdxT)
GPO: GPOL_c21970(pdxS) GPOL_c22020(pdxT)
SCO: SCO1522(SCL2.12c) SCO1523(SCL2.13c)
SMA: SAVERM_6830(pdxS) SAVERM_6831(pdxT)
SCB: SCAB_74841(pdxS) SCAB_74851(pdxT)
SCT: SCAT_5300(pdxS) SCAT_5301(pdxT)
SDV: BN159_7066(pdxS) BN159_7067(pdxT)
SLV: SLIV_30160(pdxS) SLIV_30165(pdxT)
SGU: SGLAU_06140(pdxT) SGLAU_06145(pdxS)
SAMB: SAM23877_1573(pdxT) SAM23877_1574(pdxS)
SRW: TUE45_01925(pdxT) TUE45_01926(pdxS)
SLE: sle_55880(sle_55880) sle_55890(sle_55890)
SRN: A4G23_00766(pdxT) A4G23_00767(pdxS)
SNR: SNOUR_32840(pdxS) SNOUR_32845(pdxT)
SALF: SMD44_01561(pdxT) SMD44_01562(pdxS)
SALJ: SMD11_5511(pdxS) SMD11_5512(pdxT)
SLX: SLAV_29885(pdxS) SLAV_29890(pdxT)
KSK: KSE_14470(pdxT) KSE_14480(pdxS)
TWS: TW505 TW506
CMC: CMN_01795(pdxT) CMN_01796(pdxS)
AUW: AURUGA1_00886(pdxT) AURUGA1_00887(pdxS)
ARX: ARZXY2_1659(pdxS) ARZXY2_1664(pdxT)
AAI: AARI_17500(pdxT) AARI_17600(pdxS)
KRH: KRH_01120(pdx2) KRH_01130(pdx1)
AUL: DCC27_011535(pdxS)
IDO: I598_0530(pdxS) I598_0533(pdxT)
PAW: PAZ_c10020(pdxS) PAZ_c10030(pdxT)
CGRN: 4412665_01131(pdxS) 4412665_01132(pdxT)
PFR: PFREUD_15030(pdxT) PFREUD_15040(pdxS)
ACIJ: JS278_01859(pdxT) JS278_01860(pdxS)
MPH: MLP_26660(pdxT) MLP_26680(pdxS)
NDK: I601_2964(pdxS) I601_2966(pdxT)
MGG: MPLG2_0360(pdxS) MPLG2_0361(pdxT)
NAL: B005_3739 B005_3740(pdxT)
FAL: FRAAL2136(pdx1) FRAAL2137
BSD: BLASA_2320(pdxS) BLASA_2321(pdxT)
MMAR: MODMU_3361(pdxT) MODMU_3362(pdxS)
SEN: SACE_2009(pdx1) SACE_2017
AMD: AMED_5305(pdxT) AMED_5314(pdxS)
AMM: AMES_5242(pdxT) AMES_5251(pdxS)
AMZ: B737_5242(pdxT) B737_5251(pdxS)
AOI: AORI_4428(pdxT) AORI_4439(pdxS)
AJA: AJAP_16600(pdxS) AJAP_16655(pdxT)
AMQ: AMETH_2868(pdxS) AMETH_2869(pdxT)
SESP: BN6_30550(pdxS) BN6_30670(pdxT)
AHG: AHOG_10130(pdxS) AHOG_10160(pdxT)
ASE: ACPL_6542 ACPL_6543(snz1)
ACTN: L083_6071 L083_6072(snz1)
TPYO: X956_04655
BAD: BAD_1406(pdxT) BAD_1407(pdxS)
BLA: BLA_0600 BLA_0601(pdxT)
BDE: BDP_1913(pdxT) BDP_1914(pdxS)
BBI: BBIF_0383(pdxS) BBIF_0384(pdxT)
BBF: BBB_0354(pdxS) BBB_0355(pdxT)
AYM: YM304_19820(pdxS) YM304_19830(pdxT)
GPA: GPA_31680
CBAC: JI75_04935
DEV: DhcVS_324(snz) DhcVS_538
DMC: btf_348(pdxS) btf_560(pdxT)
DMD: dcmb_394(pdxS) dcmb_606(pdxT)
DUC: UCH007_03170(pdxS) UCH007_05220(pdxT)
DFO: Dform_00959(pdxT|pdx2) Dform_01281(pdxS)
STI: Sthe_2224
ATM: ANT_01650(pdxS) ANT_01660
ABAT: CFX1CAM_0229(pdxS)
PBF: CFX0092_A1550(pdxS) CFX0092_A2279(pdxT)
PCU: pc0237 pc0238(hisH)
PNL: PNK_0250(pdxS) PNK_0251(pdxT)
PUV: PUV_27640(pdxS) PUV_27650(pdxT)
WCH: wcw_1701(pdxT) wcw_1702(pdxS)
TDE: TDE0456
TPED: TPE_1080
FNU: FN1463
FVA: FV113G1_26320(pdxS) FV113G1_26330(pdxT)
FSC: FSU_0681 FSU_0682(pdxT)
PRU: PRU_2767 PRU_2768(pdxT)
CHE: CAHE_0376(pdxS) CAHE_0377(pdxT)
MINF: MESINF_0477(pdxT) MESINF_0478(pdxS)
CEX: CSE_10820(pdxS) CSE_10830(pdxT)
CABY: Cabys_1933(pdxS) Cabys_1934
BANA: BARAN1_0960(pdxS) BARAN1_0961(pdxT)
MWO: MWSIV6_0604(pdxT) MWSIV6_1036(pdxS)
METE: tca_00172(pdxT) tca_00639(pdxS)
MST: Msp_0072(pdx1) Msp_0671
MSI: Msm_0371
MEB: Abm4_0904(pdxS) Abm4_0997(pdxT)
METH: MBMB1_1139(pdxS1) MBMB1_1411(pdxT) MBMB1_1433(pdxS3)
MFI: DSM1535_0619(pdxT) DSM1535_0631(pdxS1) DSM1535_2033(pdxS3)
MCUB: MCBB_1022(pdxS_1) MCBB_1649(pdxT) MCBB_1662(pdxS_3)
MKA: MK1062(pdx2) MK1371(snz1)
TVO: TVG0059350(TVG0059350) TVG1050816(TVG1050816)
PHO: PH1354(PH1354) PH1355(PH1355)
PAB: PAB0537 PAB0538(hisH-like)
TGA: TGAM_0629 TGAM_0630(pdxT)
MAC: MA_1566(pyrOB) MA_1567(pyrOA)
MCJ: MCON_2350(pdxT) MCON_2351
MBG: BN140_0009(pdxS)
MEMA: MMAB1_0010(pdxS)
MPD: MCP_1448(pdxS) MCP_1664(pdxT)
MEZ: Mtc_1286(pdxT) Mtc_1361(pdxS)
RCI: LRC426(pdxT) RRC68(pdxS)
HAL: VNG_1793C VNG_2598G(hisH1)
HSL: OE_3524F(pdxS) OE_4644R(pdxT)
HHB: Hhub_1116(pdxT) Hhub_3061(pdxS)
HMA: rrnAC1732 rrnAC2369(hisH1)
HHI: HAH_2264(pdxS) HAH_2808(hisH2)
NPH: NP_0464A(pdxT) NP_4528A(pdxS)
NMO: Nmlp_1256(pdxT) Nmlp_1352(pdxS)
HTI: HTIA_0015(pdxS) HTIA_1303
HWA: HQ_1301A(pdxT) HQ_3323A(pdxS)
HWC: Hqrw_1336(pdxT) Hqrw_3852(pdxS)
HVO: HVO_0436(pdxT) HVO_2336(pdxS)
HME: HFX_0401(hisH1) HFX_2345(snz1)
NMG: Nmag_1248(pdxS) Nmag_1565(pdxT)
APE: APE_0244.1(pdxT) APE_0246.1(pdxS)
ACJ: ACAM_0187(pdxT) ACAM_0188(pdxS)
STO: STK_14410(pdxS) STK_14420(pdxT)
TTN: TTX_0288(snz1) TTX_0289(pyrOB)
NID: NPIRD3C_2124(pdxT) NPIRD3C_2125(pdxS)
NIN: NADRNF5_0417(pdxS) NADRNF5_0418(pdxT)
NCT: NMSP_0286(pdxS) NMSP_0287(pdxT)
NGA: Ngar_c28470(pdxT) Ngar_c28480(pdxS)
NVN: NVIE_029420(pdxT) NVIE_029430(pdxS)
TAA: NMY3_03282(pdxS) NMY3_03283(pdxT)
NCV: NCAV_1448(pdxS) NCAV_1449(pdxT)
NBV: T478_0323 T478_0325(pdxT)
NDV: NDEV_1749(pdxT) NDEV_1750(pdxS)
 » show all
Taxonomy
Reference
1  [PMID:15771487]
  Authors
Burns KE, Xiang Y, Kinsland CL, McLafferty FW, Begley TP
  Title
Reconstitution and biochemical characterization of a new pyridoxal-5'-phosphate biosynthetic pathway.
  Journal
J Am Chem Soc 127:3682-3 (2005)
DOI:10.1021/ja042792t
Reference
2  [PMID:16030023]
  Authors
Raschle T, Amrhein N, Fitzpatrick TB
  Title
On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.
  Journal
J Biol Chem 280:32291-300 (2005)
DOI:10.1074/jbc.M501356200
Reference
3  [PMID:17159152]
  Authors
Strohmeier M, Raschle T, Mazurkiewicz J, Rippe K, Sinning I, Fitzpatrick TB, Tews I
  Title
Structure of a bacterial pyridoxal 5'-phosphate synthase complex.
  Journal
Proc Natl Acad Sci U S A 103:19284-9 (2006)
DOI:10.1073/pnas.0604950103
Reference
4  [PMID:17189272]
  Authors
Raschle T, Arigoni D, Brunisholz R, Rechsteiner H, Amrhein N, Fitzpatrick TB
  Title
Reaction mechanism of pyridoxal 5'-phosphate synthase. Detection of an enzyme-bound chromophoric intermediate.
  Journal
J Biol Chem 282:6098-105 (2007)
DOI:10.1074/jbc.M610614200
Reference
5  [PMID:18260082]
  Authors
Hanes JW, Keresztes I, Begley TP
  Title
Trapping of a chromophoric intermediate in the Pdx1-catalyzed biosynthesis of pyridoxal 5'-phosphate.
  Journal
Angew Chem Int Ed Engl 47:2102-5 (2008)
DOI:10.1002/anie.200704390
Reference
6  [PMID:18271580]
  Authors
Hanes JW, Burns KE, Hilmey DG, Chatterjee A, Dorrestein PC, Begley TP
  Title
Mechanistic studies on pyridoxal phosphate synthase: the reaction pathway leading to a chromophoric intermediate.
  Journal
J Am Chem Soc 130:3043-52 (2008)
DOI:10.1021/ja076604l
Reference
7  [PMID:18516049]
  Authors
Hanes JW, Keresztes I, Begley TP
  Title
13C NMR snapshots of the complex reaction coordinate of pyridoxal phosphate synthase.
  Journal
Nat Chem Biol 4:425-30 (2008)
DOI:10.1038/nchembio.93
Reference
8  [PMID:19152323]
  Authors
Wallner S, Neuwirth M, Flicker K, Tews I, Macheroux P
  Title
Dissection of contributions from invariant amino acids to complex formation and catalysis in the heteromeric pyridoxal 5-phosphate synthase complex from Bacillus subtilis.
  Journal
Biochemistry 48:1928-35 (2009)
DOI:10.1021/bi801887r
Other DBs
ExplorEnz - The Enzyme Database: 4.3.3.6
IUBMB Enzyme Nomenclature: 4.3.3.6
ExPASy - ENZYME nomenclature database: 4.3.3.6
BRENDA, the Enzyme Database: 4.3.3.6

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