KEGG   ENZYME: 4.4.1.14Help
Entry
EC 4.4.1.14                 Enzyme                                 

Name
1-aminocyclopropane-1-carboxylate synthase;
1-aminocyclopropanecarboxylate synthase;
1-aminocyclopropane-1-carboxylic acid synthase;
1-aminocyclopropane-1-carboxylate synthetase;
aminocyclopropanecarboxylic acid synthase;
aminocyclopropanecarboxylate synthase;
ACC synthase;
S-adenosyl-L-methionine methylthioadenosine-lyase
Class
Lyases;
Carbon-sulfur lyases;
Carbon-sulfur lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
S-adenosyl-L-methionine methylthioadenosine-lyase (1-aminocyclopropane-1-carboxylate-forming)
Reaction(IUBMB)
S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine [RN:R00179]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019]
Product
1-aminocyclopropane-1-carboxylate [CPD:C01234];
methylthioadenosine [CPD:C00170]
Comment
A pyridoxal-phosphate protein. The enzyme catalyses an alpha,gamma-elimination.
History
EC 4.4.1.14 created 1984
Pathway
ec00270  Cysteine and methionine metabolism
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01762  1-aminocyclopropane-1-carboxylate synthase
K20772  1-aminocyclopropane-1-carboxylate synthase 1/2/6
Genes
ATH: AT1G01480(ACS2) AT2G22810(ACS4) AT3G49700(ACS9) AT3G61510(ACS1) AT4G08040(ACS11) AT4G11280(ACS6) AT4G26200(ACS7) AT4G37770(ACS8) AT5G65800(ACS5)
ALY: ARALYDRAFT_327073(ACS11) ARALYDRAFT_327275(ACS6) ARALYDRAFT_332796 ARALYDRAFT_343837(ACS4) ARALYDRAFT_348080 ARALYDRAFT_490839(ACS8) ARALYDRAFT_492192(ACS7) ARALYDRAFT_667047 ARALYDRAFT_887302(ACS2)
CRB: 17875111 17878182 17880867 17881710 17883512 17886384 17886694 17889661 17898028
CSAT: 104699746 104699855 104707149 104707428 104711491 104716344 104717627 104718982 104722199 104722336 104727242 104729387 104730789 104737125 104737126 104738269 104738648 104744258 104749193 104754295 104758959 104762767 104780793 104788442 104791197
EUS: EUTSA_v10000582mg EUTSA_v10004145mg EUTSA_v10005927mg EUTSA_v10007457mg EUTSA_v10011085mg EUTSA_v10027155mg EUTSA_v10027427mg EUTSA_v10028605mg EUTSA_v10029359mg
BRP: 103833884 103835047 103837595 103841975 103844651 103855315 103857842 103858466 103860626 103861616 103864396 103865940 103873033 103874018
BNA: 106351310 106351622 106351946 106357963 106359937 106360328 106368473 106370875 106385536 106385546 106394583 106395853 106396236 106397217 106399039 106399918 106407459 106409122 106414306 106414853 106415781 106422378 106426257 106426788 106426806 106431216 106432488 106432491 106442757 106444821 106445177 106449687 106449806 111204708 111214175 111214679
BOE: 106292450 106293242 106299018 106301527 106304473 106310902 106310923 106316789 106319341 106325916 106332403 106332625 106333209 106340279
THJ: 104798348 104811738 104814722 104817315 104819275 104824936 104825800 104825862 104827602
CPAP: 110809089 110810587 110811354 110815304 110819154
LJA: Lj0g3v0243559.1(Lj0g3v0243559.1) Lj1g3v1781060.1(Lj1g3v1781060.1) Lj1g3v1781070.1(Lj1g3v1781070.1) Lj1g3v2766570.1(Lj1g3v2766570.1) Lj2g3v0909590.1(Lj2g3v0909590.1) Lj2g3v1982940.1(Lj2g3v1982940.1) Lj2g3v2051190.1(Lj2g3v2051190.1) Lj4g3v0706600.1(Lj4g3v0706600.1) Lj4g3v2990130.1(Lj4g3v2990130.1) Lj4g3v3017360.1(Lj4g3v3017360.1)
CSV: 101205326 101211475(CS-ACS1) 101212728(CS-ACS2) 101213522 101216963(ACS1) 101217331(ACS2)
CMO: 103484881 103488536(ACS11) 103492295(ACS-7) 103493143(CMe-ACS2) 103497687(CMe-ACS1)
SLY: 101246650(LE-ACS1B) 101258054 101258353 101260914 101265900 101267421 543621(LE-ACS7) 544028(ACS1A) 606300(ACS5) 606301(ACS8) 606302(ACS6) 606304(ACS2) 778292(ACS3) 778356(ACS4)
DOSA: Os01t0192900-00(Os01g0192900) Os03t0727600-01(Os03g0727600) Os04t0578000-01(Os04g0578000) Os05t0196600-00(Os05g0196600) Os05t0319200-00(Os05g0319200)
ATS: 109742142(LOC109742142) 109756625(LOC109756625) 109766279(LOC109766279) 109774526(LOC109774526)
PPP: 112280073
MNG: MNEG_8138
DFA: DFA_03166
SLD: T261_7787
LMOI: VV02_08020
 » show all
Taxonomy
Reference
1  [PMID:24317737]
  Authors
Boller T, Herner RC, Kende H
  Title
Assay for and enzymatic formation of an ethylene precursor, 1-aminocyclopropane-1-carboxylic acid.
  Journal
Planta 145:293-303 (1979)
DOI:10.1007/BF00454455
Reference
2  [PMID:507845]
  Authors
Yu YB, Adams DO, Yang SF.
  Title
1-Aminocyclopropanecarboxylate synthase, a key enzyme in ethylene biosynthesis.
  Journal
Arch Biochem Biophys 198:280-6 (1979)
DOI:10.1016/0003-9861(79)90420-X
Other DBs
ExplorEnz - The Enzyme Database: 4.4.1.14
IUBMB Enzyme Nomenclature: 4.4.1.14
ExPASy - ENZYME nomenclature database: 4.4.1.14
BRENDA, the Enzyme Database: 4.4.1.14
CAS: 72506-68-4

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