KEGG   ENZYME: 4.5.1.1Help
Entry
EC 4.5.1.1                  Enzyme                                 

Name
DDT-dehydrochlorinase;
DDT-ase;
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase;
DDTase
Class
Lyases;
Carbon-halide lyases;
Carbon-halide lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane chloride-lyase [1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene-forming]
Reaction(IUBMB)
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride [RN:R04522]
Reaction(KEGG)
Substrate
1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane [CPD:C04623]
Product
1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene [CPD:C04596];
chloride [CPD:C00698]
History
EC 4.5.1.1 created 1961
Pathway
ec00621  Dioxin degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K22678  DDT-dehydrochlorinase
Reference
1  [PMID:13673024]
  Authors
LIPKE H, KEARNS CW.
  Title
DDT dehydrochlorinase. I. Isolation, chemical properties, and spectrophotometric assay.
  Journal
J Biol Chem 234:2123-8 (1959)
Reference
2  [PMID:13673025]
  Authors
LIPKE H, KEARNS CW.
  Title
DDT dehydrochlorinase. II. Substrate and cofactor specificity.
  Journal
J Biol Chem 234:2129-32 (1959)
Reference
3
  Authors
Moorefield, H.H.
  Title
Purification of DDT-dehydrochlorinase from resistant houseflies.
  Journal
Contr Boyce Thompson Inst 18:303-310 (1956)
Other DBs
ExplorEnz - The Enzyme Database: 4.5.1.1
IUBMB Enzyme Nomenclature: 4.5.1.1
ExPASy - ENZYME nomenclature database: 4.5.1.1
UM-BBD (Biocatalysis/Biodegradation Database): 4.5.1.1
BRENDA, the Enzyme Database: 4.5.1.1
CAS: 9031-20-3

DBGET integrated database retrieval system