KEGG   ENZYME: 4.99.1.2Help
Entry
EC 4.99.1.2                 Enzyme                                 

Name
alkylmercury lyase;
organomercury lyase;
organomercurial lyase;
alkylmercury mercuric-lyase
Class
Lyases;
Other lyases;
Sole sub-subclass for lyases that do not belong in the other subclasses
BRITE hierarchy
Sysname
alkylmercury mercury(II)-lyase (alkane-forming)
Reaction(IUBMB)
an alkylmercury + H+ = an alkane + Hg2+ [RN:R03529]
Reaction(KEGG)
Substrate
alkylmercury [CPD:C01343];
H+ [CPD:C00080]
Product
alkane [CPD:C01371];
Hg2+ [CPD:C00703]
Comment
Acts on CH3Hg+ and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.
History
EC 4.99.1.2 created 1978
Orthology
K00221  alkylmercury lyase
Genes
EUN: pUMNK88_145(merB)
SEE: SNSL254_p_0164(merB)
EHM: AB284_00875
VCQ: EN18_05845
PAZO: AYR47_00245
AJO: RZ95_18695 RZ95_18770
ADV: DJ533_01870(merB) DJ533_01955(merB)
MAQ: Maqu_0243
MARA: D0851_16925(merB)
AMC: MADE_1005535 MADE_1005595
CZA: CYCME_0208(merB) CYCME_2512(merB2)
BMK: DM80_6094
BFN: OI25_7578(merB) OI25_8287(merB)
GBM: Gbem_0319
GXY: GLX_31480
GEA: GARCT_03142(merB)
SUW: SATW20_00610(merB) SATW20_p1010(merB)
SAUA: SAAG_03506
SAUZ: SAZ172_0061(merB) SAZ172_p119(merB)
SAUT: SAI1T1_10180(merB)
SAUJ: SAI2T2_20180(merB)
SAUK: SAI3T3_20180(merB)
SAUQ: SAI4T8_20180(merB)
SAUX: SAI6T6_20190(merB)
SAUR: SABB_01777(merB)
SEP: SE0086
MMI: MMAR_p10(merB)
MGI: Mflv_3214
MAB: MAB_p08
CUS: CulFRC11_0797(merB)
RHS: A3Q41_05015(merB)
GBR: Gbro_2647
ACH: Achl_4512
AMN: RAM_13730
AMM: AMES_2672
AMZ: B737_2673
AOI: AORI_2677
PDX: Psed_1314
SNA: Snas_5374
NEV: NTE_02676
 » show all
Taxonomy
Reference
1  [PMID:9382]
  Authors
Tezuka T, Tonomura K.
  Title
Purification and properties of an enzyme catalyzing the splitting of carbon-mercury linkages from mercury-resistant Pseudomonas K-62 strain. I. Splitting enzyme 1.
  Journal
J Biochem (Tokyo) 80:79-87 (1976)
Other DBs
ExplorEnz - The Enzyme Database: 4.99.1.2
IUBMB Enzyme Nomenclature: 4.99.1.2
ExPASy - ENZYME nomenclature database: 4.99.1.2
UM-BBD (Biocatalysis/Biodegradation Database): 4.99.1.2
BRENDA, the Enzyme Database: 4.99.1.2
CAS: 72560-99-7

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