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Entry
EC 5.1.3.10                 Enzyme                                 

Name
CDP-paratose 2-epimerase;
CDP-paratose epimerase;
cytidine diphosphoabequose epimerase;
cytidine diphosphodideoxyglucose epimerase;
cytidine diphosphoparatose epimerase;
cytidine diphosphate paratose-2-epimerase;
CDP-abequose epimerase (incorrect);
CDP-D-abequose 2-epimerase (incorrect);
CDP-tyvelose 2-epimerase,
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
CDP-3,6-dideoxy-D-glucose 2-epimerase
Reaction(IUBMB)
CDP-alpha-D-paratose = CDP-alpha-D-tyvelose [RN:R04266]
Reaction(KEGG)
Substrate
CDP-alpha-D-paratose [CPD:C03598]
Product
CDP-alpha-D-tyvelose
Comment
Requires NAD+.
History
EC 5.1.3.10 created 1972, modified 2005
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
Orthology
K12454  CDP-paratose 2-epimerase
Genes
STY: STY2298(rfbE)
STT: t0784(rfbE)
SEX: STBHUCCB_8360
SENT: TY21A_03975
SPT: SPA0778(rfbE)
SEK: SSPA0732(rfbE)
SED: SeD_A2428
SEG: SG2119
SEL: SPUL_0809(rfbE)
SEGA: SPUCDC_0809(rfbE)
SET: SEN2085C(rfbE)
SENA: AU38_10535
SENO: AU37_10545
SENV: AU39_10545
SENQ: AU40_11800
SENL: IY59_10830
SEEP: I137_03635
YPQ: DJ40_1356
YPR: BZ20_1043
PIN: Ping_0777
LCD: clem_00985(rfbE)
TIG: THII_1699
BSTG: WT74_16865
RTA: Rta_16030
GCA: Galf_2844
GUR: Gura_3786
GBM: Gbem_0859(tyv) Gbem_1684
GEO: Geob_2128(tyv) Geob_3241
GEM: GM21_2537
DOL: Dole_0520
MXA: MXAN_1639(rfbE)
CCX: COCOR_01687(rfbE)
SCL: sce6772 sce8935(galE6)
BMX: BMS_0380(rfbE)
MES: Meso_2779
SME: SM_b20244(tyv)
SMX: SM11_pD1367(tyv)
SMI: BN406_06422(tyv)
SMEL: SM2011_b20244(tyv)
SMER: DU99_32150
SMD: Smed_3888
SFD: USDA257_c51200(rfbE)
SAME: SAMCFNEI73_Ch3083(rfbE)
RLG: Rleg_5580
RHT: NT26_1836
BRA: BRADO2068
BRAD: BF49_5295
BRO: BRAD285_5204(rfbE)
MDI: METDI0135
MCH: Mchl_0196
MPO: Mpop_1270
MET: M446_2077
MNO: Mnod_0433
FIL: BN1229_v1_1399(rfbE)
FIY: BN1229_v1_1398(rfbE)
MSC: BN69_3019
PZU: PHZ_c2088
RSP: RSP_0519
CID: P73_4351
SJP: SJA_C1-11160(rfbB)
SPMI: K663_04900
SINB: SIDU_08660
RCE: RC1_0527(rfbE)
ALI: AZOLI_p50348(rfbE)
TMO: TMO_a0325(rfbE)
CCE: Ccel_0969
AMI: Amir_2951
SAQ: Sare_0046
MIL: ML5_0076
ASE: ACPL_6844
ACTN: L083_0049
AFS: AFR_00260
ACTS: ACWT_6714
SNA: Snas_0259
CYI: CBM981_2621(rfbE)
PMM: PMM1201
AMR: AM1_G0129
GVI: glr1179
GLJ: GKIL_1591(rfbE) GKIL_4274
NSP: BMF81_04458(rfbE) BMF81_04459(rfbE_2)
CAU: Caur_1745
PBF: CFX0092_A1594(rfbE)
DGE: Dgeo_2646
OBG: Verru16b_02012(rfbE_1) Verru16b_02015(rfbE_2)
RBA: RB7482(rfbE) RB8904(tyv)
FMR: Fuma_05606(rfbE_1) Fuma_05609(rfbE_2)
SACI: Sinac_3894
LBJ: LBJ_0629
LBL: LBL_2450
LBF: LBF_4117
LST: LSS_06934
ABAS: ACPOL_5365
ABAC: LuPra_04958(rfbE_1) LuPra_04961(rfbE_2)
EPO: Epro_0330(rfbE)
BFS: BF9343_2519(rfbE)
RMR: Rmar_1136
PSEZ: HME7025_00129(rfbB) HME7025_00130(rfbE)
COC: Coch_0704
NDE: NIDE2875(rfbE)
MAE: Maeo_0389
SALI: L593_04980
 » show all
Taxonomy
Reference
1  [PMID:5924649]
  Authors
Matsuhashi S.
  Title
Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II. Reversible 2-epimerization of cytidine diphosphate paratose.
  Journal
J Biol Chem 241:4275-82 (1966)
Reference
2  [PMID:7826006]
  Authors
Liu HW, Thorson JS.
  Title
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria.
  Journal
Annu Rev Microbiol 48:223-56 (1994)
DOI:10.1146/annurev.mi.48.100194.001255
Reference
3  [PMID:12642575]
  Authors
Koropatkin NM, Liu HW, Holden HM
  Title
High resolution x-ray structure of tyvelose epimerase from Salmonella typhi.
  Journal
J Biol Chem 278:20874-81 (2003)
DOI:10.1074/jbc.M301948200
  Sequence
[sty:STY2298]
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.10
IUBMB Enzyme Nomenclature: 5.1.3.10
ExPASy - ENZYME nomenclature database: 5.1.3.10
BRENDA, the Enzyme Database: 5.1.3.10
CAS: 37318-36-8

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