KEGG   ENZYME: 5.1.3.11Help
Entry
EC 5.1.3.11                 Enzyme                                 

Name
cellobiose epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
cellobiose 2-epimerase
Reaction(IUBMB)
cellobiose = 4-O-beta-D-glucopyranosyl-D-mannose [RN:R01445 R06245]
Reaction(KEGG)
R01445 R06245(G);
(other) R10810
Show
Substrate
cellobiose [CPD:C00185]
Product
4-O-beta-D-glucopyranosyl-D-mannose [CPD:C02964]
Comment
The enzyme catalyses the interconversion between D-glucose and D-mannose residues at the reducing end of beta-1,4-linked disaccharides by epimerizing the hydroxyl group at the C-2 position of the glucose moiety.
History
EC 5.1.3.11 created 1972
Orthology
K16213  cellobiose epimerase
Genes
VFU: vfu_B00537
VFL: AL536_06135
GAG: Glaag_3289
CATE: C2869_05850
CJA: CJA_0243(unk2)
CEB: B0D95_16675
CELL: CBR65_15155
SDE: Sde_0508
TTU: TERTU_4095
SAGA: M5M_16785
MICC: AUP74_03277(ce_1)
AXL: AXY_22460
PPY: PPE_04652
PPM: PPSC2_24205(rnbP)
PPO: PPM_4806(rnbP)
PPOL: X809_40740
PPOY: RE92_13070
PMW: B2K_12220
PRI: PRIO_2006(bfce)
CCE: Ccel_3002
CSD: Clst_1418
ESR: ES1_19350
ESU: EUS_11950
RCH: RUM_08680
RUS: RBI_II00318(ce)
FPA: FPR_17230
RIX: RO1_18080
RIM: ROI_36330
COO: CCU_23010
CPY: Cphy_2262
CSC: Csac_0294
ATE: Athe_2557
TTM: Tthe_1937
TSH: Tsac_2329
HAU: Haur_0887
ATM: ANT_18730
OTE: Oter_2309
OBG: Verru16b_01806(ce_1) Verru16b_02092(ce_2)
PLH: VT85_07185(bfce)
TTF: THTE_1735
PBOR: BSF38_02259(bfce)
ABAS: ACPOL_3507
BFR: BF0849
BFG: BF638R_0832(age)
BOA: Bovatus_02923(bfce)
BCEL: BcellWH2_02021(bfce)
PDI: BDI_0057
PSAC: PSM36_3109
PRU: PRU_1723
MBAS: ALGA_0932
RMR: Rmar_2439
CPI: Cpin_5399
FLN: FLA_5531
PHE: Phep_3983
MUC: MuYL_1513
MGOT: MgSA37_00580(ce_1) MgSA37_03676(bfce)
DFE: Dfer_1975
SLI: Slin_0271
LBY: Lbys_3430
FAE: FAES_1969
FLM: MY04_5415
FJO: Fjoh_4956
FJG: BB050_02608(bfce)
ZPR: ZPR_0358
MARF: CJ739_714
DTU: Dtur_0652
HTU: Htur_4659
SALI: L593_06560
 » show all
Taxonomy
Reference
1  [PMID:6069974]
  Authors
Tyler TR, Leatherwood JM.
  Title
Epimerization of disaccharides by enzyme preparations from Ruminococcus albus.
  Journal
Arch Biochem Biophys 119:363-7 (1967)
DOI:10.1016/0003-9861(67)90466-3
Reference
2  [PMID:18392616]
  Authors
Ito S, Taguchi H, Hamada S, Kawauchi S, Ito H, Senoura T, Watanabe J, Nishimukai M, Ito S, Matsui H
  Title
Enzymatic properties of cellobiose 2-epimerase from Ruminococcus albus and the synthesis of rare oligosaccharides by the enzyme.
  Journal
Appl Microbiol Biotechnol 79:433-41 (2008)
DOI:10.1007/s00253-008-1449-7
  Sequence
Reference
3  [PMID:23462136]
  Authors
Fujiwara T, Saburi W, Inoue S, Mori H, Matsui H, Tanaka I, Yao M
  Title
Crystal structure of Ruminococcus albus cellobiose 2-epimerase: structural insights into epimerization of unmodified sugar.
  Journal
FEBS Lett 587:840-6 (2013)
DOI:10.1016/j.febslet.2013.02.007
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.11
IUBMB Enzyme Nomenclature: 5.1.3.11
ExPASy - ENZYME nomenclature database: 5.1.3.11
BRENDA, the Enzyme Database: 5.1.3.11
CAS: 37318-37-9

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