KEGG   ENZYME: 5.1.3.12Help
Entry
EC 5.1.3.12                 Enzyme                                 

Name
UDP-glucuronate 5'-epimerase;
uridine diphosphoglucuronate 5'-epimerase;
UDP-glucuronic acid 5'-epimerase;
C-5-uronosyl epimerase
Class
Isomerases;
Racemases and epimerases;
Acting on carbohydrates and derivatives
BRITE hierarchy
Sysname
UDP-alpha-D-glucuronate 5'-epimerase
Reaction(IUBMB)
UDP-alpha-D-glucuronate = UDP-beta-L-iduronate [RN:R01387]
Reaction(KEGG)
Substrate
UDP-alpha-D-glucuronate [CPD:C00167]
Product
UDP-beta-L-iduronate
Comment
Requires NAD+.
History
EC 5.1.3.12 created 1972
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec01100  Metabolic pathways
Reference
1  [PMID:14450717]
  Authors
JACOBSON B, DAVIDSON EA.
  Title
Biosynthesis of uronic acids by skin enzymes. I. Uridine diphosphate-D-glucuronic acid-5-epimerase.
  Journal
J Biol Chem 237:638-42 (1962)
Other DBs
ExplorEnz - The Enzyme Database: 5.1.3.12
IUBMB Enzyme Nomenclature: 5.1.3.12
ExPASy - ENZYME nomenclature database: 5.1.3.12
BRENDA, the Enzyme Database: 5.1.3.12
CAS: 37318-38-0

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