KEGG   ENZYME: 5.3.99.8Help
Entry
EC 5.3.99.8                 Enzyme                                 

Name
capsanthin/capsorubin synthase;
CCS;
ketoxanthophyll synthase;
capsanthin-capsorubin synthase
Class
Isomerases;
Intramolecular oxidoreductases;
Other intramolecular oxidoreductases
BRITE hierarchy
Sysname
violaxanthin---capsorubin isomerase (ketone-forming)
Reaction(IUBMB)
(1) violaxanthin = capsorubin [RN:R07320];
(2) antheraxanthin = capsanthin [RN:R07321]
Reaction(KEGG)
Substrate
violaxanthin [CPD:C08614];
antheraxanthin [CPD:C08579]
Product
capsorubin [CPD:C08585];
capsanthin [CPD:C08584]
Comment
This multifunctional enzyme is induced during chromoplast differentiation in plants [1]. Isomerization of the epoxide ring of violaxanthin gives the cyclopentyl-ketone of capsorubin or capsanthin.
History
EC 5.3.99.8 created 2005
Pathway
ec00906  Carotenoid biosynthesis
Orthology
K14593  capsanthin/capsorubin synthase
Genes
CPAP: 110806839
CIT: 102625209
CIC: CICLE_v10028245mg
TCC: 18590279
GRA: 105799234
GHI: 107889184 107892904
DZI: 111302076
GMX: 100795360
PVU: PHAVU_005G122400g
VRA: 106779115
VAR: 108333631
CCAJ: 109817329
CAM: 101501945
LJA: Lj0g3v0210279.1(Lj0g3v0210279.1) Lj3g3v1193490.1(Lj3g3v1193490.1)
ADU: 107461762
AIP: 107614532
FVE: 101300786
MDM: 103424693
ZJU: 107410724
CSV: 105435153
CMO: 103494777
MCHA: 111012727
CMAX: 111471649
CMOS: 111434203
CPEP: 111784091
RCU: 8263068
JCU: 105632396
HBR: 110663117
JRE: 108998951
VVI: 100246737(LBCY1)
CANN: 107875664(Ccs)
NSY: 104237013
NTO: 104102870
INI: 109192897
SIND: 105170035
OEU: 111373136
HAN: 110898124
LSV: 111905371
DCR: 108227824
NNU: 104607627
EGU: 105038273
AOF: 109830421
ATR: 18441297
 » show all
Taxonomy
Reference
1  [PMID:7920703]
  Authors
Bouvier F, Hugueney P, d'Harlingue A, Kuntz M, Camara B.
  Title
Xanthophyll biosynthesis in chromoplasts: isolation and molecular cloning of an enzyme catalyzing the conversion of 5,6-epoxycarotenoid into ketocarotenoid.
  Journal
Plant J 6:45-54 (1994)
DOI:10.1046/j.1365-313X.1994.6010045.x
  Sequence
Reference
2  [PMID:9526511]
  Authors
Lefebvre V, Kuntz M, Camara B, Palloix A.
  Title
The capsanthin-capsorubin synthase gene: a candidate gene for the y locus controlling the red fruit colour in pepper.
  Journal
Plant Mol Biol 36:785-9 (1998)
Reference
3  [PMID:12549109]
  Authors
Xu CJ, Chen DM, Zhang SL.
  Title
[Molecular cloning of full length capsanthin/capsorubin synthase homologous gene from orange (Citrus sinensis)]
  Journal
Shi Yan Sheng Wu Xue Bao 34:147-50 (2001)
  Sequence
[cit:102625209]
Other DBs
ExplorEnz - The Enzyme Database: 5.3.99.8
IUBMB Enzyme Nomenclature: 5.3.99.8
ExPASy - ENZYME nomenclature database: 5.3.99.8
BRENDA, the Enzyme Database: 5.3.99.8
CAS: 162032-85-1

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