KEGG   ENZYME: 5.4.2.5Help
Entry
EC 5.4.2.5                  Enzyme                                 

Name
phosphoglucomutase (glucose-cofactor);
glucose phosphomutase;
glucose-1-phosphate phosphotransferase
Class
Isomerases;
Intramolecular transferases;
Phosphotransferases (phosphomutases)
BRITE hierarchy
Sysname
alpha-D-glucose 1,6-phosphomutase (glucose-cofactor)
Reaction(IUBMB)
alpha-D-glucose 1-phosphate = D-glucose 6-phosphate [RN:R08639]
Reaction(KEGG)
Substrate
alpha-D-glucose 1-phosphate [CPD:C00103]
Product
D-glucose 6-phosphate [CPD:C00092]
Comment
The enzyme is activated by D-glucose, which probably acts as an acceptor for a phosphate residue from the substrate, thus being itself converted into the product. cf. EC 5.4.2.2, phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent).
History
EC 5.4.2.5 created 1972 as EC 2.7.5.5, transferred 1984 to EC 5.4.2.5
Pathway
ec00520  Amino sugar and nucleotide sugar metabolism
ec01110  Biosynthesis of secondary metabolites
ec01130  Biosynthesis of antibiotics
Reference
1  [PMID:14285271]
  Authors
FUJIMOTO A, INGRAM P, SMITH RA.
  Title
D-GLUCOSE-I-PHOSPHATE:D-GLUCOSE-6-PHOSPHOTRANSFERASE.
  Journal
Biochim Biophys Acta 96:91-101 (1965)
DOI:10.1016/0005-2787(65)90613-1
Reference
2
  Authors
Ray, W.J., Jr. and Peck, E.J., Jr.
  Title
Phosphomutases.
  Journal
In: Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.
Other DBs
ExplorEnz - The Enzyme Database: 5.4.2.5
IUBMB Enzyme Nomenclature: 5.4.2.5
ExPASy - ENZYME nomenclature database: 5.4.2.5
BRENDA, the Enzyme Database: 5.4.2.5
CAS: 37278-22-1

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