KEGG   ENZYME: 5.4.99.55
Entry
EC 5.4.99.55                Enzyme                                 
Name
delta-amyrin synthase;
SlTTS2 (gene name)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, delta-amyrin-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = delta-amyrin [RN:R09915]
Reaction(KEGG)
R09915
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
delta-amyrin [CPD:C20194]
Comment
The enzyme from tomato (Solanum lycopersicum) gives 48% delta-amyrin, 18% alpha-amyrin, 13% beta-amyrin and traces of three or four other triterpenoid alcohols [1]. See also EC 5.4.99.40, alpha-amyrin synthase and EC 5.4.99.39, beta-amyrin synthase.
History
EC 5.4.99.55 created 2011
Orthology
K21928  delta/alpha/beta-amyrin synthase
Genes
SLY: 100529100(TTS2)
SOT: 102591877
SSTN: 125852109
Reference
1  [PMID:21059824]
  Authors
Wang Z, Guhling O, Yao R, Li F, Yeats TH, Rose JK, Jetter R
  Title
Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids.
  Journal
Plant Physiol 155:540-52 (2011)
DOI:10.1104/pp.110.162883
  Sequence
[sly:100529100]
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.55
IUBMB Enzyme Nomenclature: 5.4.99.55
ExPASy - ENZYME nomenclature database: 5.4.99.55
BRENDA, the Enzyme Database: 5.4.99.55

  All links  
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (3)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   InterPro (5)   
All databases (17)   

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