KEGG   ENZYME: 5.4.99.8Help
Entry
EC 5.4.99.8                 Enzyme                                 

Name
cycloartenol synthase;
2,3-epoxysqualene cycloartenol-cyclase;
squalene-2,3-epoxide-cycloartenol cyclase;
2,3-epoxysqualene-cycloartenol cyclase;
2,3-oxidosqualene-cycloartenol cyclase;
(S)-2,3-epoxysqualene mutase (cyclizing, cycloartenol-forming)
Class
Isomerases;
Intramolecular transferases;
Transferring other groups
BRITE hierarchy
Sysname
(3S)-2,3-epoxy-2,3-dihydrosqualene mutase (cyclizing, cycloartenol-forming)
Reaction(IUBMB)
(3S)-2,3-epoxy-2,3-dihydrosqualene = cycloartenol [RN:R03200]
Reaction(KEGG)
Substrate
(3S)-2,3-epoxy-2,3-dihydrosqualene [CPD:C01054]
Product
cycloartenol [CPD:C01902]
History
EC 5.4.99.8 created 1972
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K01853  cycloartenol synthase
Genes
RSS: 109440492
ATH: AT2G07050(CAS1)
ALY: ARALYDRAFT_480231
CRB: 17892775
CSAT: 104699484 104747242 104766598
EUS: EUTSA_v10002412mg EUTSA_v10003155mg
BRP: 103828738 103860345
BNA: 106357881 106389426 106390933 106439781 106452896 111213217
BOE: 106301642 106335940
THJ: 104815309
VRA: 106770354
LJA: Lj0g3v0064599.1(Lj0g3v0064599.1) Lj0g3v0064609.1(Lj0g3v0064609.1) Lj0g3v0064609.2(Lj0g3v0064609.2) Lj2g3v0914430.1(Lj2g3v0914430.1) Lj2g3v0914440.1(Lj2g3v0914440.1) Lj2g3v0914610.1(Lj2g3v0914610.1) Lj5g3v0196770.1(Lj5g3v0196770.1) Lj5g3v0196780.1(Lj5g3v0196780.1)
LANG: 109358649
CSV: 101217431
CMO: 103500608
SLY: 100147715(CAS1) 101261713
CANN: 107867693
BVG: 104893142
SOE: 110795205
OSA: 4328256
DOSA: Os02t0139700-01(Os02g0139700) Os02t0140200-01(Os02g0140200) Os02t0140400-01(Os02g0140400)
OBR: 102707275
ATS: 109736669(LOC109736669) 109751858(LOC109751858) 109764558(LOC109764558) 109769220(LOC109769220) 109771122(LOC109771122) 109771125(LOC109771125) 109772962(LOC109772962) 109785654(LOC109785654)
MUS: 103991762
DCT: 110101415
PEQ: 110039035
ATR: 18440783
PPP: 112295262
CRE: CHLREDRAFT_196409(CAS1)
APRO: F751_3159
TPS: THAPSDRAFT_277(CAS1)
 » show all
Taxonomy
Reference
1  [PMID:5797101]
  Authors
Rees HH, Goad LJ, Goodwin TW.
  Title
2,3-oxidosqualene cycloartenol cyclase from Ochromonas malhamensis.
  Journal
Biochim Biophys Acta 176:892-4 (1969)
DOI:10.1016/0005-2760(69)90274-4
Other DBs
ExplorEnz - The Enzyme Database: 5.4.99.8
IUBMB Enzyme Nomenclature: 5.4.99.8
ExPASy - ENZYME nomenclature database: 5.4.99.8
BRENDA, the Enzyme Database: 5.4.99.8
CAS: 9075-25-6

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