KEGG   ENZYME: 5.5.1.18Help
Entry
EC 5.5.1.18                 Enzyme                                 

Name
lycopene epsilon-cyclase;
CrtL-e;
LCYe;
carotenoid psi-end group lyase (decyclizing)
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
carotenoid psi-end group lyase (ring-opening)
Reaction(IUBMB)
carotenoid psi-end group = carotenoid epsilon-end group
Reaction(KEGG)
Substrate
carotenoid psi-end group
Product
carotenoid epsilon-end group
Comment
The carotenoid lycopene has the psi-end group at both ends. When acting on one end, this enzyme forms delta-carotene. When acting on both ends, it forms epsilon-carotene.
History
EC 5.5.1.18 created 2011
Pathway
ec00906  Carotenoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K06444  lycopene epsilon-cyclase
Genes
ATH: AT5G57030(LUT2)
ALY: ARALYDRAFT_918865
CRB: 17874924
CSAT: 104733913 104761775 109124564
EUS: EUTSA_v10013234mg
BRP: 103845139 103854515 103856778
BNA: 106371493 106387316 106418464 106436514
BOE: 106313003 106328183
THJ: 104811752
CPAP: 110817683
CIT: 102578059
TCC: 18588358
DZI: 111300372
EGR: 104438073
VRA: 106761979
VAR: 108331502
CCAJ: 109803443
CAM: 101509804
LJA: Lj6g3v1211980.1(Lj6g3v1211980.1)
ADU: 107479054
AIP: 107630506
LANG: 109328578
FVE: 101304999
PPER: 18771479
PAVI: 110749277
MDM: 103450601
PXB: 103951887
ZJU: 107424069
CSV: 101213753
CMO: 103498607(LCYE)
MCHA: 111021848
RCU: 8272573
JCU: 105637892
HBR: 110633595
POP: 18100367
JRE: 109009968
VVI: 100259482(LECY1)
SLY: 544129(CrtL-e-1)
SPEN: 107007293
SOT: 102577922(LCYe)
NTA: 107789691(LYCe) 107830918
NSY: 104228679
NTO: 104113690
INI: 109148024
SIND: 105161879
OEU: 111366340
LSV: 111905476
CCAV: 112501264
DCR: 108197060
BVG: 104909057
SOE: 110791410
NNU: 104600661
OSA: 4324196
DOSA: Os01t0581300-01(Os01g0581300)
OBR: 102717564
BDI: 100821922
ATS: 109738556(LOC109738556)
SBI: 8078213
ZMA: 100280448(lyce1)
SITA: 101764899
PDA: 103723715
EGU: 105057721
MUS: 103988322
DCT: 110115201
PEQ: 110030128
AOF: 109835611
ATR: 18444744
CRE: CHLREDRAFT_187094(LCYE)
MNG: MNEG_1848
CVR: CHLNCDRAFT_19656(LCYE)
APRO: F751_6574
PMA: Pro_0790(lcyE)
PMM: PMM0633(crtL2)
PMT: PMT_1773
PRC: EW14_0680
PRM: EW15_0738
 » show all
Taxonomy
Reference
1  [PMID:11226339]
  Authors
Cunningham FX Jr, Gantt E.
  Title
One ring or two? Determination of ring number in carotenoids by lycopene epsilon-cyclases.
  Journal
Proc Natl Acad Sci U S A 98:2905-10 (2001)
DOI:10.1073/pnas.051618398
  Sequence
[ath:AT5G57030]
Reference
2  [PMID:12712234]
  Authors
Stickforth P, Steiger S, Hess WR, Sandmann G.
  Title
A novel type of lycopene epsilon-cyclase in the marine cyanobacterium Prochlorococcus marinus MED4.
  Journal
Arch Microbiol 179:409-15 (2003)
DOI:10.1007/s00203-003-0545-4
Other DBs
ExplorEnz - The Enzyme Database: 5.5.1.18
IUBMB Enzyme Nomenclature: 5.5.1.18
ExPASy - ENZYME nomenclature database: 5.5.1.18
BRENDA, the Enzyme Database: 5.5.1.18

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