KEGG   ENZYME: 5.5.1.9Help
Entry
EC 5.5.1.9                  Enzyme                                 

Name
cycloeucalenol cycloisomerase;
cycloeucalenol---obtusifoliol isomerase;
cycloeucalenol lyase (cyclopropane-decyclizing)
Class
Isomerases;
Intramolecular lyases;
Intramolecular lyases (only sub-subclass identified to date)
BRITE hierarchy
Sysname
cycloeucalenol lyase (cyclopropane-ring opening)
Reaction(IUBMB)
cycloeucalenol = obtusifoliol [RN:R03775]
Reaction(KEGG)
Substrate
cycloeucalenol [CPD:C02141]
Product
obtusifoliol [CPD:C01943]
Comment
Opens the cyclopropane ring of a number of related 4alpha-methyl-9beta-19-cyclosterols, but not those with a 4beta-methyl group, with formation of an 8(9) double bond. Involved in the synthesis of plant sterols.
History
EC 5.5.1.9 created 1986
Pathway
ec00100  Steroid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K08246  cycloeucalenol cycloisomerase
Genes
AQU: 100633507
ATH: AT5G50375(CPI1)
ALY: ARALYDRAFT_495101
CRB: 17875827
CSAT: 104725142 104725553 104761032
EUS: EUTSA_v10014300mg
BRP: 103842220 103858451
BNA: 106368587 106388428 106388465 106388470 106395079
BOE: 106311073 106334665
THJ: 104803145
CPAP: 110820324
CIT: 102630846
TCC: 18605081
GRA: 105786328
GHI: 107941049
DZI: 111289822
EGR: 104426171
VRA: 106752757
VAR: 108322558
CCAJ: 109797244
CAM: 101498621
LJA: Lj6g3v0984700.1(Lj6g3v0984700.1)
ADU: 107463495
LANG: 109326998
FVE: 101310407
PPER: 18777316
PMUM: 103338046
PAVI: 110762938
ZJU: 107404400
CSV: 101215719
CMO: 103484362
MCHA: 111008866
RCU: 8266323
JCU: 105640216
POP: 7454702
VVI: 100262783
SLY: 100301930(CYC1)
SPEN: 107007161
SOT: 102603067
CANN: 107851175
NSY: 104212751
NTO: 104106158
INI: 109158212
SIND: 105171061
OEU: 111382474
HAN: 110879898
LSV: 111877353
CCAV: 112509434
BVG: 104894046
SOE: 110787305
NNU: 104591683
OSA: 9270960
DOSA: Os11t0302500-01(Os11g0302500)
OBR: 102700845
BDI: 100834141
ATS: 109737590(LOC109737590) 109737950(LOC109737950) 109767330(LOC109767330) 109785596(LOC109785596)
ZMA: 100283632
SITA: 101757137
PDA: 103708538
DCT: 110108578
AOF: 109844540
ATR: 18423006
PPP: 112291331
CRE: CHLREDRAFT_193038(CPI1)
MNG: MNEG_2071
APRO: F751_6325
MGR: MGG_15431
DFA: DFA_11434
 » show all
Taxonomy
Reference
1  [PMID:4369016]
  Authors
Heintz R, Benveniste P.
  Title
Plant sterol metabolism. Enzymatic cleavage of the 9beta, 19beta-cyclopropane ring of cyclopropyl sterols in bramble tissue cultures.
  Journal
J Biol Chem 249:4267-74 (1974)
Reference
2
  Authors
Rahier, A., Schmitt, P. and Benveniste, P.
  Title
7-oxo-24xi(28)-dihydrocycloeucalenol, a potent inhibitor of plant sterol biosynthesis.
  Journal
Phytochemistry 21:1969-1974 (1982)
Other DBs
ExplorEnz - The Enzyme Database: 5.5.1.9
IUBMB Enzyme Nomenclature: 5.5.1.9
ExPASy - ENZYME nomenclature database: 5.5.1.9
BRENDA, the Enzyme Database: 5.5.1.9
CAS: 60496-19-7

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