KEGG   Equus przewalskii (Przewalski's horse): 103559087
Entry
103559087         CDS       T04644                                 
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase 1
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
epz  Equus przewalskii (Przewalski's horse)
Pathway
epz00260  Glycine, serine and threonine metabolism
epz00630  Glyoxylate and dicarboxylate metabolism
epz00670  One carbon pool by folate
epz01100  Metabolic pathways
epz01200  Carbon metabolism
epz01230  Biosynthesis of amino acids
epz01240  Biosynthesis of cofactors
epz01523  Antifolate resistance
Module
epz_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:epz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    103559087 (SHMT1)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    103559087 (SHMT1)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    103559087 (SHMT1)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103559087 (SHMT1)
Enzymes [BR:epz01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     103559087 (SHMT1)
SSDB
Motif
Pfam: SHMT DegT_DnrJ_EryC1
Other DBs
NCBI-GeneID: 103559087
NCBI-ProteinID: XP_008530660
Position
Un
AA seq 484 aa
MATPVNGAHENADLWSSHDKMMAQPLKDSDTEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELELLCQKRALQLYDLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPETGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKESLYNLESLISAAVFPRL
HGGPHNHAIAGVAVALKQAMTPEFRLYQRQVVANCRALAESLMALGYTVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKEFQK
VAQFIHRGIELTLQIQNDVGIKATLKEFKEKLAGDEKHQQAVRALREEVESFASLFPLPG
LPAF
NT seq 1455 nt   +upstreamnt  +downstreamnt
atggcgactccagtcaatggggcccacgagaatgctgacctgtggtcctcacatgataaa
atgatggcacagccccttaaagacagcgacactgaggtttataacatcattaagaaggag
agtaaccggcagagggtcggattggagctgatcgcgtccgagaactttgccagccgagcc
gttttagaggccctgggctcttgcttaaataacaagtactctgaggggtacccaggccag
aggtattacggcgggactgagtttatcgatgaactggagctcctctgtcagaagcgagcg
ctgcagctctatgatctggacccccagtgctggggggtcaacgtccagccctactcaggc
tcccctgcaaacttcgcagtgtacaccgccctggtggagccccatgggcgcatcatgggc
ctggacctgcccgatgggggccacttgacccatgggttcatgacagacaagaagaaaatc
tctgctacatccatcttttttgaatctatgccctataaggtgaacccagagactggctac
atcaactacgaccagctggaggaaaatgctcgcctcttccacccaaagctcattatcgca
ggaaccagctgctactcccgaaacctggactacgctcgattgcggaagattgcagatgac
aatggggcgtatctcatggctgacatggcacacatcagtgggctggtggcggctggtgtg
gtgccctcccccttcgagcactgccacgtggtgtccaccaccacccacaaaaccctgcga
ggctgccgggctggcatgatcttctacaggagaggagtgcgcagtgtggatcccaagact
ggcaaagagagcctgtacaacctagagtcactcatcagcgccgccgtgttcccacgcctc
cacggaggtccccacaaccacgccatcgctggggttgctgtggccctgaagcaagccatg
actccggaattcagactctatcagcgccaggtggtggccaactgcagggctctggctgag
agcttgatggcactgggctacacagtagtaacaggtggttctgacaaccatttgatcctc
gtggatctccgttccaaaggcacagatggtggcagggctgagaaggtgctagaagcctgt
tctattgcctgcaacaagaacacctgcccaggtgacagaagtgcactgcggcccagcgga
ctgcgactggggaccccagcactgacctcccgcgggcttttggaaaaagagttccaaaaa
gtagcccagtttattcatagagggatagaactgactctgcagattcagaatgatgtgggc
atcaaggccaccctgaaggagttcaaggagaaactggcaggggacgagaagcaccaacag
gctgtcagggctctgagggaggaggtggagagcttcgcctctctcttccctctgcccggc
ctgcctgccttctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (13)   
   KEGG PATHWAY (8)   
   KEGG MODULE (5)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (34)   

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