KEGG   PATHWAY: etc00061Help
Entry
etc00061                    Pathway                                

Name
Fatty acid biosynthesis - Edwardsiella piscicida C07-087
Class
Metabolism; Lipid metabolism
BRITE hierarchy
Pathway map
etc00061  Fatty acid biosynthesis
etc00061

Ortholog table
Module
etc_M00082  Fatty acid biosynthesis, initiation [PATH:etc00061]
etc_M00083  Fatty acid biosynthesis, elongation [PATH:etc00061]
etc_M00086  beta-Oxidation, acyl-CoA synthesis [PATH:etc00061]
Organism
Edwardsiella piscicida C07-087 [GN:etc]
Gene
ETAC_03640  acetyl-CoA carboxylase carboxyltransferase subunit alpha [KO:K01962] [EC:2.1.3.15 6.4.1.2]
ETAC_14995  acetyl-CoA carboxylase biotin carboxyl carrier protein [KO:K02160]
ETAC_15000  acetyl-CoA carboxylase biotin carboxylase subunit [KO:K01961] [EC:6.3.4.14 6.4.1.2]
ETAC_11425  Acetyl-coenzyme A carboxyl transferase beta chain [KO:K01963] [EC:2.1.3.15 6.4.1.2]
ETAC_09975  Malonyl CoA-acyl carrier protein transacylase [KO:K00645] [EC:2.3.1.39]
ETAC_09980  3-oxoacyl-(acyl carrier protein) synthase III [KO:K00648] [EC:2.3.1.180]
ETAC_03970  3-oxoacyl-(acyl carrier protein) synthase I [KO:K00647] [EC:2.3.1.41]
ETAC_11465  Beta-ketoacyl synthase, C-terminal domain protein [KO:K00647] [EC:2.3.1.41]
ETAC_03955  3-oxoacyl-(acyl carrier protein) synthase II [KO:K09458] [EC:2.3.1.179]
ETAC_09960  3-oxoacyl-(acyl carrier protein) synthase II [KO:K09458] [EC:2.3.1.179]
ETAC_03960  fabG; 3-ketoacyl-(acyl-carrier-protein) reductase [KO:K00059] [EC:1.1.1.100]
ETAC_11395  short-chain dehydrogenase/reductase SDR [KO:K00059] [EC:1.1.1.100]
ETAC_09970  fabG; 3-ketoacyl-(acyl-carrier-protein) reductase [KO:K00059] [EC:1.1.1.100]
ETAC_06000  3-hydroxydecanoyl-(acyl carrier protein) dehydratase [KO:K01716] [EC:5.3.3.14 4.2.1.59]
ETAC_03615  (3R)-hydroxymyristoyl-ACP dehydratase [KO:K02372] [EC:4.2.1.59]
ETAC_08580  trans-2-enoyl-CoA reductase [KO:K00209] [EC:1.3.1.44 1.3.1.9]
ETAC_03020  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
ETAC_06860  long-chain-fatty-acid--CoA ligase [KO:K01897] [EC:6.2.1.3]
Compound
C00024  Acetyl-CoA
C00083  Malonyl-CoA
C00154  Palmitoyl-CoA
C00173  Acyl-[acyl-carrier protein]
C00229  Acyl-carrier protein
C00249  Hexadecanoic acid
C00383  Malonate
C00638  Long-chain fatty acid
C00685  3-Oxoacyl-[acyl-carrier protein]
C00693  trans-2,3-Dehydroacyl-[acyl-carrier protein]
C00712  (9Z)-Octadecenoic acid
C01203  Oleoyl-[acyl-carrier protein]
C01209  Malonyl-[acyl-carrier protein]
C01271  (3R)-3-Hydroxyacyl-[acyl-carrier protein]
C01530  Octadecanoic acid
C01571  Decanoic acid
C02679  Dodecanoic acid
C02843  Long-chain acyl-CoA
C03939  Acetyl-[acyl-carrier protein]
C04088  Octadecanoyl-[acyl-carrier protein]
C04180  cis-Dec-3-enoyl-[acp]
C04246  But-2-enoyl-[acyl-carrier protein]
C04618  (3R)-3-Hydroxybutanoyl-[acyl-carrier protein]
C04619  (3R)-3-Hydroxydecanoyl-[acyl-carrier protein]
C04620  (3R)-3-Hydroxyoctanoyl-[acyl-carrier protein]
C04633  (3R)-3-Hydroxypalmitoyl-[acyl-carrier protein]
C04688  (3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein]
C05223  Dodecanoyl-[acyl-carrier protein]
C05744  Acetoacetyl-[acp]
C05745  Butyryl-[acp]
C05746  3-Oxohexanoyl-[acp]
C05747  (R)-3-Hydroxyhexanoyl-[acp]
C05748  trans-Hex-2-enoyl-[acp]
C05749  Hexanoyl-[acp]
C05750  3-Oxooctanoyl-[acp]
C05751  trans-Oct-2-enoyl-[acp]
C05752  Octanoyl-[acp]
C05753  3-Oxodecanoyl-[acp]
C05754  trans-Dec-2-enoyl-[acp]
C05755  Decanoyl-[acp]
C05756  3-Oxododecanoyl-[acp]
C05757  (R)-3-Hydroxydodecanoyl-[acp]
C05758  trans-Dodec-2-enoyl-[acp]
C05759  3-Oxotetradecanoyl-[acp]
C05760  trans-Tetradec-2-enoyl-[acp]
C05761  Tetradecanoyl-[acp]
C05762  3-Oxohexadecanoyl-[acp]
C05763  trans-Hexadec-2-enoyl-[acp]
C05764  Hexadecanoyl-[acp]
C06423  Octanoic acid
C06424  Tetradecanoic acid
C08362  (9Z)-Hexadecenoic acid
C16219  3-Oxostearoyl-[acp]
C16220  (R)-3-Hydroxyoctadecanoyl-[acp]
C16221  (2E)-Octadecenoyl-[acp]
C16520  Hexadecenoyl-[acyl-carrier protein]
C20683  Long-chain acyl-[acyl-carrier protein]
C20794  n-7 Unsaturated acyl-[acyl-carrier protein]
Reference
  Authors
Salas JJ, Ohlrogge JB.
  Title
Characterization of substrate specificity of plant FatA and FatB acyl-ACP thioesterases.
  Journal
Arch Biochem Biophys 403:25-34 (2002)
DOI:10.1016/S0003-9861(02)00017-6
Reference
  Authors
Zhang YM, Marrakchi H, White SW, Rock CO.
  Title
The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase.
  Journal
J Lipid Res 44:1-10 (2003)
DOI:10.1194/jlr.R200016-JLR200
Reference
  Authors
Voelker T, Kinney AJ.
  Title
VARIATIONS IN THE BIOSYNTHESIS OF SEED-STORAGE LIPIDS.
  Journal
Annu Rev Plant Physiol Plant Mol Biol 52:335-361 (2001)
DOI:10.1146/annurev.arplant.52.1.335
Reference
  Authors
Barker GC, Larson TR, Graham IA, Lynn JR, King GJ.
  Title
Novel insights into seed fatty acid synthesis and modification pathways from genetic diversity and quantitative trait Loci analysis of the Brassica C genome.
  Journal
Plant Physiol 144:1827-42 (2007)
DOI:10.1104/pp.107.096172
Reference
  Authors
Bowman CE, Wolfgang MJ
  Title
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
  Journal
Adv Biol Regul 71:34-40 (2019)
DOI:10.1016/j.jbior.2018.09.002
Reference
  Authors
Venkatesan R, Sah-Teli SK, Awoniyi LO, Jiang G, Prus P, Kastaniotis AJ, Hiltunen JK, Wierenga RK, Chen Z
  Title
Insights into mitochondrial fatty acid synthesis from the structure of heterotetrameric 3-ketoacyl-ACP reductase/3R-hydroxyacyl-CoA dehydrogenase.
  Journal
Nat Commun 5:4805 (2014)
DOI:10.1038/ncomms5805
Reference
  Authors
Hiltunen JK, Chen Z, Haapalainen AM, Wierenga RK, Kastaniotis AJ
  Title
Mitochondrial fatty acid synthesis--an adopted set of enzymes making a pathway of major importance for the cellular metabolism.
  Journal
Prog Lipid Res 49:27-45 (2010)
DOI:10.1016/j.plipres.2009.08.001
Reference
  Authors
Kastaniotis AJ, Autio KJ, Keratar JM, Monteuuis G, Makela AM, Nair RR, Pietikainen LP, Shvetsova A, Chen Z, Hiltunen JK
  Title
Mitochondrial fatty acid synthesis, fatty acids and mitochondrial physiology.
  Journal
Biochim Biophys Acta Mol Cell Biol Lipids 1862:39-48 (2017)
DOI:10.1016/j.bbalip.2016.08.011
KO pathway
ko00061   

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