KEGG   Felis catus (domestic cat): 101082828Help
Entry
101082828         CDS       T02385                                 

Gene name
PLA2G4E
Definition
(RefSeq) cytosolic phospholipase A2 epsilon isoform X1
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00564  Glycerophospholipid metabolism
fca00565  Ether lipid metabolism
fca00590  Arachidonic acid metabolism
fca00591  Linoleic acid metabolism
fca00592  alpha-Linolenic acid metabolism
fca01100  Metabolic pathways
fca04010  MAPK signaling pathway
fca04014  Ras signaling pathway
fca04072  Phospholipase D signaling pathway
fca04217  Necroptosis
fca04270  Vascular smooth muscle contraction
fca04370  VEGF signaling pathway
fca04611  Platelet activation
fca04664  Fc epsilon RI signaling pathway
fca04666  Fc gamma R-mediated phagocytosis
fca04724  Glutamatergic synapse
fca04726  Serotonergic synapse
fca04730  Long-term depression
fca04750  Inflammatory mediator regulation of TRP channels
fca04912  GnRH signaling pathway
fca04913  Ovarian steroidogenesis
fca04921  Oxytocin signaling pathway
fca05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    101082828 (PLA2G4E)
   00565 Ether lipid metabolism
    101082828 (PLA2G4E)
   00590 Arachidonic acid metabolism
    101082828 (PLA2G4E)
   00591 Linoleic acid metabolism
    101082828 (PLA2G4E)
   00592 alpha-Linolenic acid metabolism
    101082828 (PLA2G4E)
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    101082828 (PLA2G4E)
   04010 MAPK signaling pathway
    101082828 (PLA2G4E)
   04370 VEGF signaling pathway
    101082828 (PLA2G4E)
   04072 Phospholipase D signaling pathway
    101082828 (PLA2G4E)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    101082828 (PLA2G4E)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101082828 (PLA2G4E)
   04664 Fc epsilon RI signaling pathway
    101082828 (PLA2G4E)
   04666 Fc gamma R-mediated phagocytosis
    101082828 (PLA2G4E)
  09152 Endocrine system
   04912 GnRH signaling pathway
    101082828 (PLA2G4E)
   04913 Ovarian steroidogenesis
    101082828 (PLA2G4E)
   04921 Oxytocin signaling pathway
    101082828 (PLA2G4E)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    101082828 (PLA2G4E)
  09156 Nervous system
   04724 Glutamatergic synapse
    101082828 (PLA2G4E)
   04726 Serotonergic synapse
    101082828 (PLA2G4E)
   04730 Long-term depression
    101082828 (PLA2G4E)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101082828 (PLA2G4E)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    101082828 (PLA2G4E)
Enzymes [BR:fca01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     101082828 (PLA2G4E)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: cPLA2_C2 PLA2_B C2 CEP76-C2
Motif
Other DBs
NCBI-GeneID: 101082828
NCBI-ProteinID: XP_003987300
Ensembl: ENSFCAG00000007352
UniProt: M3W7K6
Position
B3
AA seq 862 aa AA seqDB search
MTLQSSEGCPGLGTDVFAPQVLQGAEESRSERDVSEFEHTQDLETPSLPPLLPTALGGSQ
GGVSPCHLLTVKVIRMKNVRQADMVSQTDCFVSLWLPTASRERLRTRTISNCPNPEWNET
FSFQIQSQVKNVLELSICDEDTVTPNDHLLTVLYDLTKLCFRKKTHMKFPLNPEGMEELE
VEFLLEESPFPPETLITNGVLVSRQVSCLEVHAECRRQKKSRKMKDLLVTVKESFEHTQR
VSHCQEPCCPNLACFHYPKYFQPQMHVEVPKSQWSCGPCCCCARKNSPICQPLDCLPDGQ
AVTLPVGESCELHVKSTPCPQTLDVRLGFSLCQAELEFLQKRKVVVAEALKQVLQLEEDL
HTDEVPLIAIMATGGGARSMTAMYGHLLGLQKLNILNCASYITGLSGATWTMATLYRDPD
WSSKNLEPAIFEARRHVVKDKMPALFPDQLCKFQEELRQRSQEGYKVTFTDFWGLLIEAC
LGDERNECKLSDQRAALSQGQNPLPIYLTINVKDDVSNQDFREWCEFSPYEVGLQKYGAF
IPTELFGSEFFMGRLMKRIPESRMCYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTRDK
VHDIEDEPLLPEIPKCDANILDTAVVIPGSWLSNTFRSILTHRSFVSEFHNFLLGLQLHT
DYLQNSQFSMWRDTVLDTFPNQLTGSVNHLCLLDTAFFVNSSYPPLLRPERKVDLIIHLN
YCAGSQTKPMKQTCEYCSVQNIPFPKYEVQEGDENLKECYLIENSQEPDAPIVIFFPLIN
DTFQKYKAPGVERSPEELEQGHVDIYGPKTPYATKELTYTEAAFDKLVKLSEYNILNNKD
KLFQALRLAVEKKKRLKSQCPS
NT seq 2589 nt NT seq  +upstreamnt  +downstreamnt
atgactctccagagctcggaaggctgtcctggcctgggaactgatgtgtttgccccacag
gtgctacagggggctgaagagagcaggtcggaaagagatgtcagtgagtttgagcacaca
caggacctggaaactcccagtctcccacctctgcttcccacggcccttgggggctctcag
ggtggggtctctccatgccacctgctgacagtgaaggtcatccggatgaaaaatgtccgg
caggctgatatggtgagccagacagactgctttgtgagcctttggctgcccaccgcttct
cgtgaaaggctgaggactaggaccatctccaactgcccaaacccagagtggaatgaaacc
ttcagcttccagatccagagccaagtgaagaacgtgctggagctgagcatctgtgatgaa
gacacagtgacaccaaatgaccacctgttgacagtcctctatgacctcaccaagctctgc
ttccgaaagaaaacccatatgaagttcccactcaacccagagggcatggaagagctggag
gtagagttcctgctggaggagagtccctttccacctgagaccctcatcaccaacggcgtg
ctggtgtctcgacaagtctcctgcctagaggttcatgcagaatgcaggaggcagaagaag
agcaggaaaatgaaggacctcctggtgacagtaaaggagtcctttgagcacacccagcgc
gtctcgcactgccaggagccctgctgcccgaacctggcctgcttccactaccccaagtac
ttccagccccagatgcacgtggaagtgcccaagagccagtggagctgtgggccctgctgc
tgctgtgcgcgcaagaacagccctatctgccagcccctcgattgccttcctgatggccag
gcggtgaccctgccggtgggtgagagctgtgagttacacgtgaagtctacaccctgcccc
cagacgcttgacgtgcggctgggcttcagcctatgccaggcagagctggagtttctgcag
aagcggaaggtggtggtggccgaggcactgaaacaggtgttgcagctggaggaggacctg
catacggacgaggtaccattgatagccatcatggccactgggggtggagcaagatccatg
accgccatgtacggccacctgctggggctgcagaagctgaacatcctgaactgtgccagc
tacatcactggcctgtcaggggccacctggaccatggctaccttgtaccgtgatcctgac
tggtcctccaaaaacctggagccggccatatttgaggcacggaggcatgtggtcaaggac
aagatgcctgccctattcccagaccagctctgcaaattccaggaggagcttcggcagcgc
agtcaggaaggctacaaggtcacctttacagatttctggggccttctgattgaggcctgt
ctgggggatgagagaaatgaatgcaaactgtcagatcagcgtgctgctttatcccagggc
cagaaccccctgcccatctacctcaccatcaatgtcaaggatgatgtaagcaaccaggat
ttcagagagtggtgcgagttctccccctacgaagtgggcctgcagaagtacggcgccttc
atccccactgagctcttcggatccgagttcttcatggggcggctgatgaaaaggatccca
gagtcaaggatgtgctacatgctaggtttgtggagcagcatcttctccctgaacttgctc
gatgcctggaatctgtcccatacctcagaggagtttttccacaggtggacgagggataaa
gtgcacgacattgaagatgagccactcctgcctgaaatccccaaatgtgatgccaacatc
ttggacaccgcggtggtgatcccagggtcctggttgtccaatactttccgcagcatcctc
acccataggtccttcgtgtctgagttccacaatttcctgttggggctgcagctgcacacc
gactacctccagaacagccagttctccatgtggagagacacggtgctagatactttcccg
aaccagctgacggggtccgtgaaccacttgtgcctgttggacactgcattctttgtcaat
tccagctacccgcccctccttaggcctgagagaaaagtcgacctcatcatccacctcaat
tactgtgctgggtcccagacaaagcccatgaaacaaacctgtgagtactgctctgtgcag
aatatccccttccccaaatacgaagtgcaagagggggacgaaaatctcaaggagtgctac
ctgatagagaactcccaagaacctgatgctcccattgtgattttcttcccactcatcaat
gacaccttccagaagtacaaggccccaggtgtggagaggagccccgaggagctggagcag
ggccacgttgacatttatggccccaaaactccgtatgctaccaaggagctgacatacaca
gaggccgcctttgacaagctggtgaagctctctgagtacaacatcctgaataacaaagac
aagctctttcaggccctgagactggcggtggagaagaagaaacgcctgaagagccaatgt
ccctcctaa

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