KEGG   Felis catus (domestic cat): 101085162
Entry
101085162         CDS       T02385                                 
Symbol
SMURF2
Name
(RefSeq) E3 ubiquitin-protein ligase SMURF2 isoform X1
  KO
K04678  E3 ubiquitin ligase SMURF1/2 [EC:2.3.2.26]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04120  Ubiquitin mediated proteolysis
fca04137  Mitophagy - animal
fca04144  Endocytosis
fca04340  Hedgehog signaling pathway
fca04350  TGF-beta signaling pathway
fca04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:fca00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    101085162 (SMURF2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    101085162 (SMURF2)
   04350 TGF-beta signaling pathway
    101085162 (SMURF2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101085162 (SMURF2)
   04137 Mitophagy - animal
    101085162 (SMURF2)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    101085162 (SMURF2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    101085162 (SMURF2)
   04121 Ubiquitin system [BR:fca04121]
    101085162 (SMURF2)
   03029 Mitochondrial biogenesis [BR:fca03029]
    101085162 (SMURF2)
Enzymes [BR:fca01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     101085162 (SMURF2)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Ubiquitin E3 ligases
    101085162 (SMURF2)
 Autophagy
  Mitophagy
   Other mitophagy associated  proteins
    101085162 (SMURF2)
Ubiquitin system [BR:fca04121]
 Ubiquitin ligases (E3)
  HECT type E3
   101085162 (SMURF2)
Mitochondrial biogenesis [BR:fca03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-independent mechanism factors
    101085162 (SMURF2)
SSDB
Motif
Pfam: HECT WW C2 GpA_nuclease 2-thiour_desulf
Other DBs
NCBI-GeneID: 101085162
NCBI-ProteinID: XP_023099468
EnsemblRapid: ENSFCTG00005025744
Position
E1:complement(47155396..47274002)
AA seq 748 aa
MSNPGGRRNGPVKLRLTVLCAKNLVKKDFFRLPDPFAKVVVDGSGQCHSTDTVKNTLDPK
WNQHYDLYIGKSDSVTISVWNHKKIHKKQGAGFLGCVRLLSNAINRLKDTGYQRLDLCKL
GPNDNDTVRGQIVVSLQSRDRIGTGGQVVDCSRLFDNDLPDGWEERRTASGRIQYLNHIT
RTTQWERPTRPASEYSSPGRPLSCFVDENTPISGTNGATCGQSSDPRLAERRVRSQRHRN
YMSRTHLHTPPDLPEGYEQRTTQQGQVYFLHTQTGVSTWHDPRVPRDLSNINCEELGPLP
PGWEIRNTATGRVYFVDHNNRTTQFTDPRLSANLHLVLNRQNQLKDQQQQQVVSLCPDDA
ECLTVPRYKRDLVQKLKILRQELSQQQPQAGHCRIEVSREEIFEESYRQVMKMRPKDLWK
RLMIKFRGEEGLDYGGVAREWLYLLSHEMLNPYYGLFQYSRDDIYTLQINPDSAVNPEHL
SYFHFVGRIMGMAVFHGHYIDGGFTLPFYKQLLGKSITLDDMELVDPDLHNSLVWILEND
ITGVLDHTFCVEHNAYGEIIQHELKPNGKSIPVTEENKKEYVRLYVNWRFLRGIEAQFLA
LQKGFNEVIPQHLLKTFDEKELELIICGLGKIDVNDWKVNTRLKHCTPDSNVVKWFWKAV
EFFDEERRARLLQFVTGSSRVPLQGFKALQGAAGPRLFTIHQIDACTNNLPKAHTCFNRI
DIPPYESYEKLYEKLLTAIEETCGFAVE
NT seq 2247 nt   +upstreamnt  +downstreamnt
atgtctaaccctgggggccggaggaacgggcccgtcaagctgcgcctgacagtactctgt
gcaaaaaacttggtgaaaaaggattttttccgacttcctgatccatttgctaaggtggtg
gttgatggatctgggcaatgccattctacagatactgtgaagaatacacttgatccaaag
tggaatcagcattatgacctgtatattggaaagtctgattcagttacgatcagtgtatgg
aatcacaagaagatccataaaaaacaaggtgctggatttcttggttgtgttcgacttctt
tccaatgccatcaaccgcctcaaagacactggttatcagaggttggatctatgcaaactt
gggccaaatgacaacgatacagttagaggacagatagtagtaagccttcagtccagagac
cggataggcacaggaggacaagttgtggactgcagtcgtttatttgataatgatttacca
gatggctgggaagaaaggcgaactgcctctggaagaatccagtatctaaaccacataaca
agaactacacagtgggaacgcccaacacgaccagcatctgaatattctagtcccggcaga
cctcttagctgctttgttgatgagaacactccaattagtggaacaaatggtgcaacgtgt
ggacagtcttcggatcccagactggccgagaggagagtccggtcacaacgacatagaaat
tacatgagcaggacacatttacatactcctccagacctaccagaaggctatgagcagagg
acaacacagcaaggtcaggtgtatttcttacatactcagactggtgtgagcacgtggcat
gatccaagagtgcctagggatcttagcaacatcaattgtgaagagcttggtccattgcct
cctggatgggagatccgtaatactgcaacaggcagagtttatttcgttgaccacaacaac
agaacgacacaatttacagatcctcggctctctgctaacttgcatttagttttaaatcgg
cagaaccagttgaaagaccaacagcaacagcaggtggtatcgttatgtcccgatgatgca
gagtgtctgacagtcccacggtacaagcgagacctggttcagaagttaaaaattttgcgg
caagaactttcccaacaacagcctcaggctggtcattgccgcattgaggtttccagggaa
gagatttttgaggaatcatatcggcaggtcatgaaaatgagaccaaaagatctgtggaag
cgattaatgataaaatttcgtggagaagaaggccttgactatggaggggttgccagggag
tggttatatctgttgtcacatgaaatgttgaatccttactatggcctcttccagtattca
agagatgatatctatacattgcagatcaatcctgattctgcagtcaatccggaacattta
tcctatttccactttgttggacgaataatgggaatggccgtgtttcacggacattacatt
gatggtggcttcacattgcctttttataaacagttgctcgggaagtccattactttggat
gacatggagttagttgatccagatcttcacaacagtttggtgtggattcttgagaatgat
attacaggtgttttggaccataccttctgtgtcgaacataatgcatatggtgaaattatt
cagcatgaacttaaaccaaatggcaagagtatccctgttactgaagaaaataaaaaagaa
tatgtcaggctctacgtgaactggagatttttacgaggcattgaggcacagttcctggct
ctgcagaaaggatttaatgaagtaattccacagcatctgctgaagacattcgatgagaag
gagttagagctcattatttgtggacttggaaagatagatgttaatgactggaaggtaaac
acccggttaaaacactgcacgccagacagcaatgtcgtcaagtggttctggaaagctgtg
gagttctttgatgaagagcgaagagcacggttacttcagtttgtgacaggatcatctaga
gtgcctctgcagggcttcaaggctttacaaggtgctgctggcccacgactcttcaccata
caccagatcgatgcctgcaccaacaacctgccaaaggcccacacgtgcttcaatcgaata
gacattccgccctatgaaagctatgaaaagttatacgaaaagctgctaacggccatcgaa
gagacatgtgggtttgctgtggaatga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (5)   
   Pfam (5)   
All databases (42)   

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