KEGG   Felis catus (domestic cat): 101085431
Entry
101085431         CDS       T02385                                 
Symbol
SQSTM1
Name
(RefSeq) sequestosome-1 isoform X2
  KO
K14381  sequestosome 1
Organism
fca  Felis catus (domestic cat)
Pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04217  Necroptosis
fca04218  Cellular senescence
fca04380  Osteoclast differentiation
fca05014  Amyotrophic lateral sclerosis
fca05022  Pathways of neurodegeneration - multiple diseases
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101085431 (SQSTM1)
   04137 Mitophagy - animal
    101085431 (SQSTM1)
  09143 Cell growth and death
   04217 Necroptosis
    101085431 (SQSTM1)
   04218 Cellular senescence
    101085431 (SQSTM1)
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101085431 (SQSTM1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    101085431 (SQSTM1)
   05022 Pathways of neurodegeneration - multiple diseases
    101085431 (SQSTM1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101085431 (SQSTM1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    101085431 (SQSTM1)
   03029 Mitochondrial biogenesis [BR:fca03029]
    101085431 (SQSTM1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    101085431 (SQSTM1)
Membrane trafficking [BR:fca04131]
 Autophagy
  Mitophagy
   Cargo receptors
    101085431 (SQSTM1)
  Pexophagy
    101085431 (SQSTM1)
  Aggrephagy
    101085431 (SQSTM1)
  Xenophagy
    101085431 (SQSTM1)
  Other autophagy associated proteins
   Midbophagy
    101085431 (SQSTM1)
Mitochondrial biogenesis [BR:fca03029]
 Mitochondrial quality control factors
  Mitophagy factors
   Parkin-dependent mechanism factors
    101085431 (SQSTM1)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101085431 (SQSTM1)
SSDB
Motif
Pfam: UBA_5 PB1 ZZ
Other DBs
NCBI-GeneID: 101085431
NCBI-ProteinID: XP_003980695
EnsemblRapid: ENSFCTG00005022123
UniProt: M3WL63
Position
A1:complement(90408755..90434182)
AA seq 443 aa
MASLTVKAYLLGKEDAAREIRRFSFCFSPEPEAEAEAEAEVAAGPGPCERLLSRVAALFP
ALRPGGFQTHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHHPPCAQE
APRGMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCAACEGKGLHREHNKLVFPTTFGPFS
EGFSHSRWLRKLKHGHFGWPGWEMGPPGNWSPRPPRAGDARPSPAAESASGPSEDPSVNF
LKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPGSSSTEEKCSSQPSSCSSDPSKP
DGDTEGAARSLAEQMDKIALEPGQPEEQMESDNCSGGDEDWTHLSSKEVDPSTGELQSLQ
MPESEGPASLDSSQEGPTGLKEAAVYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLL
QTKNYDIGAALDTIQYSKHPLPL
NT seq 1332 nt   +upstreamnt  +downstreamnt
atggcgtcgctcaccgtcaaggcctaccttctgggcaaggaggacgcggcccgtgagatc
cgccgcttcagcttctgcttcagcccagaacccgaggcggaggcggaggccgaggcggag
gtcgcggctgggcccggaccctgcgaacggctgctgagccgggtggccgccctgttcccc
gcgctgcggcccggaggcttccagacgcactatcgcgatgaggacggagacttggttgcc
ttttccagcgacgaggagctgaccatggcaatgtcctatgtgaaggatgacatcttccgt
atttacattaaagagaagaaggagtgccggcgggaccaccaccccccgtgtgctcaggag
gcaccccgcggcatggtgcaccccaacgtgatctgtgatggttgcaatgggccggtggtg
gggacccgctacaaatgcagcgtctgcccggactatgacttgtgtgctgcctgtgagggg
aagggcttgcacagagagcacaacaagcttgtcttccccaccacctttgggcccttctcc
gagggcttctcgcatagccgctggctccggaaactgaaacatgggcactttgggtggccc
ggctgggagatgggcccaccggggaattggagcccacgtccccctcgtgcaggggatgcc
cgccccagccctgcggcggagtcagcttctggcccatcagaggaccccagcgtgaatttc
cttaagaatgtaggggagagtgtggcagctgccctcagccctctgggcatcgaagtggat
attgacgtggaacatggagggaagagaagccgcctcacgcccgtctctccaggcagctcc
agcacggaggagaagtgtagctctcagccgagcagttgctcttctgatcccagcaaaccg
gacggggacacggagggtgccgcgcggtctctggcagagcagatggacaagatagctcta
gagccggggcagcctgaggaacagatggagtctgataactgttcaggaggggacgaggac
tggactcatttatcttcaaaagaagtagacccgtctacaggtgaactccagtctctacag
atgcccgagtccgaagggccagcctccctagactcttctcaggaagggcccacagggctg
aaggaggccgcggtgtacccacatctgcccccagaagctgacccccggctgatagaatcc
ctctcccagatgctgtccatggggttctcagacgaaggcggctggctcaccaggctccta
cagaccaagaactatgacatcggggctgccctggacaccatccagtattcaaagcatcca
ctgccattgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (45)   

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