KEGG   Felis catus (domestic cat): 101097351Help
Entry
101097351         CDS       T02385                                 

Gene name
GSTO1
Definition
(RefSeq) glutathione S-transferase omega-1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00480  Glutathione metabolism
fca00980  Metabolism of xenobiotics by cytochrome P450
fca00982  Drug metabolism - cytochrome P450
fca00983  Drug metabolism - other enzymes
fca01524  Platinum drug resistance
fca05200  Pathways in cancer
fca05204  Chemical carcinogenesis
fca05225  Hepatocellular carcinoma
fca05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:fca00001]
 Metabolism
  Metabolism of other amino acids
   00480 Glutathione metabolism
    101097351 (GSTO1)
  Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101097351 (GSTO1)
   00982 Drug metabolism - cytochrome P450
    101097351 (GSTO1)
   00983 Drug metabolism - other enzymes
    101097351 (GSTO1)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    101097351 (GSTO1)
   05204 Chemical carcinogenesis
    101097351 (GSTO1)
   05225 Hepatocellular carcinoma
    101097351 (GSTO1)
  Cardiovascular diseases
   05418 Fluid shear stress and atherosclerosis
    101097351 (GSTO1)
  Drug resistance
   01524 Platinum drug resistance
    101097351 (GSTO1)
Enzymes [BR:fca01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101097351 (GSTO1)
Transporters [BR:fca02000]
 Other Transporters
  Pores ion channels [TC:1]
   101097351 (GSTO1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: GST_N_3 GST_N_2 GST_N GST_C_3 GST_C GST_C_2 Glutaredoxin GST_C_5
Motif
Other DBs
NCBI-GeneID: 101097351
NCBI-ProteinID: XP_019669354
UniProt: M3WTU7
Position
D2
AA seq 241 aa AA seqDB search
MSGGSARSLAKGSAPPGPVPQGLIRVYSMRFCPFAQRTLLVLKAKGIGHEIININLKNKP
EWFFTKNPFGLVPVLENSQGQLIYESAITCEYLDEAYPGKKLLPDDPYEKACQKMVFELF
SKVPPLVTSFIRRQNNEDGSGLKEELRKEFSKLEEVLTNKKTTFFGGNSLSMIDYLIWPW
FERLEVLELNECVDHTPKLKLWMAAMREDPAVSSLLIEAKAFRGFLDLYLQNSPEACDYG
L
NT seq 726 nt NT seq  +upstreamnt  +downstreamnt
atgtccggagggtcagccaggagcctagcgaagggaagcgcgcccccggggccggtcccc
cagggcctgatccgcgtctacagcatgaggttctgcccgttcgcccagaggacgctcctg
gtcctgaaggccaagggaattgggcatgaaatcatcaacatcaacctgaaaaataagcct
gagtggttctttacgaagaatccctttggtctggtgccagttctggaaaacagtcagggt
caactgatctatgaatctgccattacttgtgagtacctggatgaagcatatccagggaag
aagctgttgccagatgacccctatgagaaagcttgccaaaagatggtctttgagttattt
tctaaggttccccctttggtaacaagcttcattagaagacaaaataatgaagacggctct
ggcctaaaagaagaattgcgtaaagaattcagcaagttagaggaggttctgaccaataag
aagacaaccttctttggtggcaattctctttctatgattgattacctcatctggccctgg
tttgaacggctcgaagttctggagttaaatgagtgtgtagatcacactccaaaacttaag
ctctggatggcagccatgagggaagatcctgcagtgtcctccctcctcattgaggcgaag
gcctttcgaggtttcttagatctctacttgcagaacagccctgaggcctgtgattatggg
ctctga

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