KEGG   Felis catus (domestic cat): 101097735
Entry
101097735         CDS       T02385                                 

Gene name
ADCY4
Definition
(RefSeq) adenylate cyclase type 4
  KO
K08044  adenylate cyclase 4 [EC:4.6.1.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00230  Purine metabolism
fca01100  Metabolic pathways
fca01522  Endocrine resistance
fca04015  Rap1 signaling pathway
fca04020  Calcium signaling pathway
fca04022  cGMP-PKG signaling pathway
fca04024  cAMP signaling pathway
fca04062  Chemokine signaling pathway
fca04072  Phospholipase D signaling pathway
fca04114  Oocyte meiosis
fca04211  Longevity regulating pathway
fca04213  Longevity regulating pathway - multiple species
fca04261  Adrenergic signaling in cardiomyocytes
fca04270  Vascular smooth muscle contraction
fca04371  Apelin signaling pathway
fca04540  Gap junction
fca04611  Platelet activation
fca04713  Circadian entrainment
fca04714  Thermogenesis
fca04723  Retrograde endocannabinoid signaling
fca04724  Glutamatergic synapse
fca04725  Cholinergic synapse
fca04727  GABAergic synapse
fca04742  Taste transduction
fca04750  Inflammatory mediator regulation of TRP channels
fca04911  Insulin secretion
fca04912  GnRH signaling pathway
fca04913  Ovarian steroidogenesis
fca04914  Progesterone-mediated oocyte maturation
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04918  Thyroid hormone synthesis
fca04921  Oxytocin signaling pathway
fca04923  Regulation of lipolysis in adipocytes
fca04925  Aldosterone synthesis and secretion
fca04926  Relaxin signaling pathway
fca04927  Cortisol synthesis and secretion
fca04928  Parathyroid hormone synthesis, secretion and action
fca04934  Cushing syndrome
fca04935  Growth hormone synthesis, secretion and action
fca04970  Salivary secretion
fca04971  Gastric acid secretion
fca04972  Pancreatic secretion
fca04976  Bile secretion
fca05032  Morphine addiction
fca05163  Human cytomegalovirus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05200  Pathways in cancer
fca05414  Dilated cardiomyopathy (DCM)
Brite
KEGG Orthology (KO) [BR:fca00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101097735 (ADCY4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101097735 (ADCY4)
   04371 Apelin signaling pathway
    101097735 (ADCY4)
   04020 Calcium signaling pathway
    101097735 (ADCY4)
   04072 Phospholipase D signaling pathway
    101097735 (ADCY4)
   04024 cAMP signaling pathway
    101097735 (ADCY4)
   04022 cGMP-PKG signaling pathway
    101097735 (ADCY4)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101097735 (ADCY4)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101097735 (ADCY4)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101097735 (ADCY4)
   04062 Chemokine signaling pathway
    101097735 (ADCY4)
  09152 Endocrine system
   04911 Insulin secretion
    101097735 (ADCY4)
   04923 Regulation of lipolysis in adipocytes
    101097735 (ADCY4)
   04912 GnRH signaling pathway
    101097735 (ADCY4)
   04913 Ovarian steroidogenesis
    101097735 (ADCY4)
   04915 Estrogen signaling pathway
    101097735 (ADCY4)
   04914 Progesterone-mediated oocyte maturation
    101097735 (ADCY4)
   04921 Oxytocin signaling pathway
    101097735 (ADCY4)
   04926 Relaxin signaling pathway
    101097735 (ADCY4)
   04935 Growth hormone synthesis, secretion and action
    101097735 (ADCY4)
   04918 Thyroid hormone synthesis
    101097735 (ADCY4)
   04928 Parathyroid hormone synthesis, secretion and action
    101097735 (ADCY4)
   04916 Melanogenesis
    101097735 (ADCY4)
   04925 Aldosterone synthesis and secretion
    101097735 (ADCY4)
   04927 Cortisol synthesis and secretion
    101097735 (ADCY4)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101097735 (ADCY4)
   04270 Vascular smooth muscle contraction
    101097735 (ADCY4)
  09154 Digestive system
   04970 Salivary secretion
    101097735 (ADCY4)
   04971 Gastric acid secretion
    101097735 (ADCY4)
   04972 Pancreatic secretion
    101097735 (ADCY4)
   04976 Bile secretion
    101097735 (ADCY4)
  09156 Nervous system
   04724 Glutamatergic synapse
    101097735 (ADCY4)
   04727 GABAergic synapse
    101097735 (ADCY4)
   04725 Cholinergic synapse
    101097735 (ADCY4)
   04723 Retrograde endocannabinoid signaling
    101097735 (ADCY4)
  09157 Sensory system
   04742 Taste transduction
    101097735 (ADCY4)
   04750 Inflammatory mediator regulation of TRP channels
    101097735 (ADCY4)
  09149 Aging
   04211 Longevity regulating pathway
    101097735 (ADCY4)
   04213 Longevity regulating pathway - multiple species
    101097735 (ADCY4)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101097735 (ADCY4)
   04714 Thermogenesis
    101097735 (ADCY4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101097735 (ADCY4)
  09165 Substance dependence
   05032 Morphine addiction
    101097735 (ADCY4)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    101097735 (ADCY4)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101097735 (ADCY4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101097735 (ADCY4)
   05163 Human cytomegalovirus infection
    101097735 (ADCY4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101097735 (ADCY4)
Enzymes [BR:fca01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101097735 (ADCY4)
SSDB
Motif
Pfam: Guanylate_cyc DUF1053 AC_N CD52
Other DBs
NCBI-GeneID: 101097735
NCBI-ProteinID: XP_023111950
Ensembl: ENSFCAG00000005600
Position
B3
AA seq 1036 aa
MARLFSPRPPPSEDLFYETYYSLSQQYPLLLLLLVIVLCALLALLAVASASGRELASDPG
FLTTVLCALGGFSLLLGLASREQRLQRWTRPLSGLVWAALLGLGHGFLFTGGLVSAWDQV
SFFLFVIFTVYAMLPLGMRDAAAAGLASSLSHLLVLGLYLGPQPDSKPALLPQLAANAVL
FLCGNVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMK
AEIMARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNE
LFGKFDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATG
VDINMRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHITGATLALLAG
AYAVEDAAMEHRDPYLRELGEPTYLVIDPRAEEEDEKGTAGGLLSSLEGPKMRPSLLMTR
YLESWGAAKPFAHLSHLESPVSTSTPLPEKALASFSPQWSLDRSRTPRGLDDDLDTGDAK
FFQVIEQLNSQKQWRQSKDFNPLTLYFRKKELEKEYRLSALPAFKYYAACTFLVFLSNFI
IQMLVTNRPPACIPKSAEPQHKPPSCPGSCLPTSALHFLLQFFLPAASNCPFGTLNVSSM
AFNISWELPGSLPLISVPYSMHCCVLGFLSCSLFLHMSFELKLLLLLLWLGASCSLFLHS
HAWLSDCLIARLYPDPSDSRPGVLKEPKLMGAISFFIFFFTLLVLARQNEYYCRLDFLWK
KKLRQEQEETETMENLTRLLLENVLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPD
FKEFYSESNINHEGLECLRLLNEIIADFDELLSKPKFSGVEKIKTIGSTYMAATGLNATS
GQDAQQDAERSCSHLGTMVEFAVALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQK
PQYDIWGNTVNVASRMESTGVLGKIQVTEETARVLQSLGYTCYSRGIIKVKGKGQLCTYF
LNTDLARTGPPSATLG
NT seq 3111 nt   +upstreamnt  +downstreamnt
atggcccgcctcttcagcccccggccgccccccagcgaagacctcttctacgaaacctac
tacagcctgagccagcagtacccgctgctgctactgctgctggtgatcgtgctctgcgcg
ctcctggcgctgctggctgtcgcctccgccagcggccgggagctagcttcagacccaggc
ttcctgaccactgtgctgtgcgcgctgggtggcttctcgctgctcctgggcctggcttcc
cgggagcaacgactgcagcgctggacacgtcccctgtcgggcctcgtatgggcagcgcta
ctcgggctaggccacggcttcctgttcactgggggcctggtgagcgcctgggaccaggtg
tcctttttcctctttgtcatcttcaccgtgtatgccatgttgcccttgggtatgcgggat
gccgctgctgcgggccttgcctcatcgctctcccacttgctggtccttgggctgtacctt
gggcctcagccggactcaaagccggcgctgctgccacagctggcagcgaacgcggtgttg
ttcctgtgcgggaacgtggcgggagcgtatcacaaggcgctgatggaacgcgcgctgcgc
gccacgttccgcgaggcacttagctccctgcactcgcgccggcggctggacaccgagaag
aagcaccaggaacaccttctcttgtccatccttcctgcctacttggcccgagagatgaag
gcagagatcatggcacgactgcaggctggacaggggtcacggccagaaagcaccaacaac
ttccacagcctctatgtcaagaggcaccagggagtcagtgtgctgtatgctgacatcgtg
ggcttcacccggctggccagtgagtgctctcctaaggagttggtgctcatgctcaacgag
ctctttggcaagttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctg
ggagactgttactactgtgtctctgggctaccgctctccctgccagaccacgccatcaac
tgcgtgcgcatggggctggacatgtgccgggccatcaggaagctccgggcagccactggc
gtggacatcaacatgcgtgtgggcgtgcattcgggcagtgtgctctgcggagtcattggg
ctgcagaagtggcagtatgatgtctggtcccatgatgtcacactggccaaccacatggag
gcgggtggcgtgccaggacgagtgcatattacaggggctaccctggccctgctggcaggg
gcttatgctgtggaggatgcagccatggaacaccgggacccataccttcgggagctaggg
gagcctacctacctagtcatcgatccccgggctgaggaggaggatgagaagggcactgca
ggagggttgctgtcctctctcgagggccccaagatgcgtccgtcgctgctgatgacccgc
tacctggagtcctggggcgccgccaagccttttgcccatctgagccacctagagagccct
gtgtccacctctacccctctcccggagaaggccctggcttccttcagcccccagtggagc
ctggaccggagccgtaccccccgggggctagatgatgacctggacactggggatgccaag
ttcttccaggtcatcgaacagctcaactctcagaaacagtggaggcagtcaaaggacttc
aacccactgacactgtacttcagaaagaaggaactggagaaagagtaccgactctctgcc
ctccccgccttcaaatactatgcagcctgcaccttcctggttttcctttccaatttcatc
atccagatgctggtgacaaacaggcccccagcctgcatccctaagtcagctgaaccccag
cacaagccaccatcgtgcccagggagctgcctgcccacctcagctcttcacttccttctg
cagttcttcttaccggcagcatcaaactgcccttttgggactctcaatgtgtcctccatg
gctttcaacatctcctgggagctccctgggtccctgcctctcatcagcgtcccctactct
atgcactgctgcgtgctggggttcctgtcctgctccctctttttgcacatgagcttcgag
ctgaagttgctgctgctcctgctatggctgggggcctcctgctccctcttcctgcactcc
cacgcctggctgtccgactgcctcatcgcccgcctctatccggatccctcggactccagg
ccaggggtgctgaaggagcccaaactgatgggagctatctccttcttcatcttcttcttc
accctcctggtcctggctcggcagaatgagtattactgccggctggacttcctgtggaag
aagaagctgcggcaggagcaggaggagacagagaccatggagaacctgactcggctgctg
ttggagaatgtgctccctgcacatgtggccccccagttcattggccagaaccggcgcaac
gaggacctctaccaccagtcctatgagtgtgtctgtgtcctgttcgcctcagttccagac
ttcaaggagttttactctgagtccaacataaaccacgagggtctagagtgtctgcggctg
ctcaatgagataattgctgattttgatgagctgctctcaaagcccaagtttagcggggtg
gagaagatcaaaaccatcggtagcacctacatggcagctacaggcttaaatgccacctcc
ggacaggacgcacagcaggacgctgagcgcagctgcagccaccttggcaccatggtggag
tttgcggtggctcttggatcaaagctggacgtcatcaataagcactctttcaacaacttc
cgcttgcgtgtggggttgaatcacggacctgtagtggctggagtgatcggggcccagaag
ccgcagtatgacatctggggcaacacagtgaacgtggccagccgcatggagagtacagga
gtcctgggcaagatccaggtgaccgaagagacggcccgggtgctgcagtccttaggctac
acctgctacagccggggtatcatcaaggtcaaaggcaaagggcagctctgcacctacttt
ctgaacacagatttggcacgaactggacctccctcggccaccctaggctga

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