KEGG   Felis catus (domestic cat): 101098453Help
Entry
101098453         CDS       T02385                                 

Definition
(RefSeq) LOW QUALITY PROTEIN: guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas
  KO
K04632  guanine nucleotide-binding protein G(s) subunit alpha
Organism
fca  Felis catus (domestic cat)
Pathway
fca01522  Endocrine resistance
fca04015  Rap1 signaling pathway
fca04020  Calcium signaling pathway
fca04024  cAMP signaling pathway
fca04072  Phospholipase D signaling pathway
fca04261  Adrenergic signaling in cardiomyocytes
fca04270  Vascular smooth muscle contraction
fca04540  Gap junction
fca04611  Platelet activation
fca04713  Circadian entrainment
fca04714  Thermogenesis
fca04724  Glutamatergic synapse
fca04726  Serotonergic synapse
fca04728  Dopaminergic synapse
fca04730  Long-term depression
fca04750  Inflammatory mediator regulation of TRP channels
fca04911  Insulin secretion
fca04912  GnRH signaling pathway
fca04913  Ovarian steroidogenesis
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04918  Thyroid hormone synthesis
fca04921  Oxytocin signaling pathway
fca04922  Glucagon signaling pathway
fca04923  Regulation of lipolysis in adipocytes
fca04924  Renin secretion
fca04925  Aldosterone synthesis and secretion
fca04926  Relaxin signaling pathway
fca04927  Cortisol synthesis and secretion
fca04928  Parathyroid hormone synthesis, secretion and action
fca04934  Cushing syndrome
fca04961  Endocrine and other factor-regulated calcium reabsorption
fca04962  Vasopressin-regulated water reabsorption
fca04970  Salivary secretion
fca04971  Gastric acid secretion
fca04972  Pancreatic secretion
fca04976  Bile secretion
fca05030  Cocaine addiction
fca05031  Amphetamine addiction
fca05032  Morphine addiction
fca05034  Alcoholism
fca05142  Chagas disease (American trypanosomiasis)
fca05146  Amoebiasis
fca05163  Human cytomegalovirus infection
fca05165  Human papillomavirus infection
fca05200  Pathways in cancer
fca05414  Dilated cardiomyopathy (DCM)
Module
fca_M00695  cAMP signaling
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101098453
   04020 Calcium signaling pathway
    101098453
   04072 Phospholipase D signaling pathway
    101098453
   04024 cAMP signaling pathway
    101098453
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101098453
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101098453
  09152 Endocrine system
   04911 Insulin secretion
    101098453
   04922 Glucagon signaling pathway
    101098453
   04923 Regulation of lipolysis in adipocytes
    101098453
   04912 GnRH signaling pathway
    101098453
   04913 Ovarian steroidogenesis
    101098453
   04915 Estrogen signaling pathway
    101098453
   04921 Oxytocin signaling pathway
    101098453
   04926 Relaxin signaling pathway
    101098453
   04918 Thyroid hormone synthesis
    101098453
   04928 Parathyroid hormone synthesis, secretion and action
    101098453
   04916 Melanogenesis
    101098453
   04924 Renin secretion
    101098453
   04925 Aldosterone synthesis and secretion
    101098453
   04927 Cortisol synthesis and secretion
    101098453
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101098453
   04270 Vascular smooth muscle contraction
    101098453
  09154 Digestive system
   04970 Salivary secretion
    101098453
   04971 Gastric acid secretion
    101098453
   04972 Pancreatic secretion
    101098453
   04976 Bile secretion
    101098453
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101098453
   04961 Endocrine and other factor-regulated calcium reabsorption
    101098453
  09156 Nervous system
   04724 Glutamatergic synapse
    101098453
   04728 Dopaminergic synapse
    101098453
   04726 Serotonergic synapse
    101098453
   04730 Long-term depression
    101098453
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101098453
  09159 Environmental adaptation
   04713 Circadian entrainment
    101098453
   04714 Thermogenesis
    101098453
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101098453
  09165 Substance dependence
   05030 Cocaine addiction
    101098453
   05031 Amphetamine addiction
    101098453
   05032 Morphine addiction
    101098453
   05034 Alcoholism
    101098453
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    101098453
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101098453
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    101098453
   05165 Human papillomavirus infection
    101098453
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101098453
   05142 Chagas disease (American trypanosomiasis)
    101098453
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101098453
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    101098453
   04031 GTP-binding proteins [BR:fca04031]
    101098453
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101098453
  Exosomal proteins of other body fluids (saliva and urine)
   101098453
  Exosomal proteins of colorectal cancer cells
   101098453
  Exosomal proteins of bladder cancer cells
   101098453
GTP-binding proteins [BR:fca04031]
 Heterotrimeric G-proteins
  Alpha Subunits
   Alpha type 2 (Gs)
    101098453
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-alpha Arf Gtr1_RagA Roc
Motif
Other DBs
NCBI-GeneID: 101098453
NCBI-ProteinID: XP_023106831
Position
A3
AA seq 969 aa AA seqDB search
MGVRNCLDGNNMSGQRDIPLELGEQPEQPPLEAPGAAAPSPGPGAAEEMETEPPHSEPVP
LEIEGEACGPPEVSGPNCQDLGQAIEETRALGGYSPPPEEAMPFEVEQPSPGGFWPTLEQ
PGDTTGAHAGPEVFSPTVMEPGAFDDARPGLGGYSPPPEEAMPFEFEQPAQGGCSQPLLQ
VSDLAPGGPGAGVFSTPPQEPGALKPATTGFRGDCSPPPEEAMPFEFDGAAFGDDSPPPG
LPRAIPQIDGGSIGQPAAVAVPSAVLLAPAANEPPLWVPGAIGSPSREAVRSPPHFAGDS
PPMEISGPPLEIGSAPVGVDDAPVNMDSPPIALDGPPIEVSGAPVKRERAEGERPPVEGE
AAEMEGGSAAASAAGRGKVPSPGDGAPAAGADRASPAAGAAPAAPAAPAAGAAAAAPAAP
AAGAAPAARAAPAAPAAPAAGAAPAARAAPAAPASGARPKLRFLRPPSPEIQAADPPTPQ
PTRAFAWRGRSGRGRDDDERSVSSDDDHSSDESDDGTSGCRRWLQPRRNRRRRKPRRNLL
RKFLMQAFGGCFGRSESPQPKAAPSPKVKKIPLAEKRRQMRKEALEKRAQKRAEKKRSQL
IDKQLQEEKMGYMCTHRLLLLGAGESGKSTIVKQMRILHVNGFNGEGGEEDPQAARSNSD
GEKATKVQDIKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPE
FYEHAKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQADYVPSDQDLLRCRVLTS
GIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYNMVIREDNQTNR
LQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDAT
PEPGEDPRVTRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQR
MHLRQYELL
NT seq 2910 nt NT seq  +upstreamnt  +downstreamnt
atgggcgtgcgcaactgcctcgacggcaataatatgtcaggacaacgcgatatccccctt
gaactcggggaacagcccgagcaaccacccttggaggccccaggggcagctgcccccagt
cctgggcctggcgcagccgaagagatggagaccgaaccgcctcacagcgagcccgtcccc
ctcgagattgaaggcgaggcctgtggaccccccgaggtctccggacccaactgccaggac
ctgggccaggccatcgaggaaaccagagccctcggaggctacagcccacctcctgaggaa
gccatgcccttcgaggtcgagcagcccagcccaggaggcttctggcctaccctggagcag
cccggagacaccactggggcccatgcaggccctgaggtcttcagcccaacggtcatggag
cccggagccttcgatgatgccagacccggcctgggaggctacagccctccacctgaagaa
gccatgccctttgagtttgagcagcctgcacagggaggttgcagccagcctctcctgcag
gtctcagacctcgctccaggaggcccaggtgcaggggtcttcagcactcctccccaggag
cctggagccctcaagcctgcaaccacaggcttcagaggagactgtagtcctccccctgag
gaggctatgccatttgagtttgatggagcagcctttggggacgacagcccaccccccggg
ctcccccgagctatcccacaaatcgacggcggcagcatcggccagcccgcggcagtcgcg
gtcccgagtgcggtcctcctcgctcccgccgcgaacgagccccccctctgggtccccggc
gccatcggcagcccatcccgagaggctgtcagatctcctccacacttcgcgggcgacagc
cccccgatggagatctccggacccccgctcgagattggcagcgcccccgttggggtcgac
gacgctcccgtcaacatggacagccccccaatcgcgcttgacggcccgcccatcgaggtc
tccggagccccagttaagagagagcgagcagagggagagagacccccagttgagggagaa
gcagccgagatggaaggaggctcagccgccgcctctgctgcggggagaggaaaagtcccc
tctcccggggacggagccccagcggccggggccgaccgtgcttctccagccgccggggca
gccccagccgcccctgccgctccagccgccggggcagccgctgccgcccctgccgctccg
gccgccggggcagctccagccgccagggcagctcctgccgcccctgccgctccggccgcc
ggggcagctcctgccgcccgggcagcccctgccgcccctgcgtctggagcccgacccaag
ctccgcttcctccgaccccccagccccgagatccaggctgccgatccgcctactccgcag
cctactcgcgcatttgcctggcggggcaggtctggccgcggccgcgacgacgacgagagg
tcggtcagcagcgacgacgaccacagcagcgatgaatccgacgatgggacctccggatgc
cgccgctggctgcagccccggcgaaatcgccgccgccgaaagccccggcgcaacttgctc
cgcaagttcctcatgcaggccttcgggggctgcttcggccgatccgagagcccccagccc
aaagccgcccccagccccaaggtcaagaagattcccctggcggagaagcgcagacagatg
cgcaaggaagccctggagaagcgcgcccagaagcgcgcagagaagaaacgcagccagctc
atcgacaaacaactccaggaagaaaagatggggtacatgtgtacgcaccgcctgctgctt
ctaggtgctggagaatctggtaaaagcaccattgtgaagcaaatgaggattctgcatgtt
aatgggtttaatggagagggcggcgaagaggacccgcaggctgccaggagcaacagcgat
ggtgagaaggcaaccaaagtgcaggacatcaaaaacaacctgaaagaggccatcgaaacc
atcgtggccgccatgagcaacctggtcccccccgtggagctggccaaccctgagaaccag
ttcagagtggactacattctgagcgtgatgaacgtgcccgacttcgacttccctcccgag
ttctacgagcacgccaaggctctgtgggaggacgaaggagtgcgtgcctgctatgagcgc
tccaacgagtaccagctgattgactgcgcccagtacttcctggacaagatcgatgtcatc
aagcaggctgactacgtgcccagtgaccaggatctgcttcgctgccgcgtcctgacttct
ggaatctttgagaccaagttccaggtggacaaagtcaacttccacatgttcgacgtgggt
ggccagcgtgacgagcgccgcaaatggatccagtgcttcaacgatgtgactgccattatc
ttcgtggtggccagcagcagctacaacatggtcattcgggaggacaatcagaccaaccgc
ctgcaggaggctctgaacctcttcaagagcatctggaacaacagatggctgcgcaccatc
tccgtgatcctgttcctcaacaagcaagacctgctcgctgagaaagtcctcgctggaaaa
tcgaaaattgaggactactttccagaatttgctcgctacactactcccgaggatgctact
cccgagcccggagaggacccacgcgtgacccgggccaagtacttcatccgcgacgaattt
ctgagaatcagcactgccagtggagacgggcgtcactactgctatccccacttcacttgc
gccgtggacaccgagaacatccgccgtgtgttcaacgactgccgtgacatcattcagcgc
atgcaccttcgtcagtacgagctgctctaa

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