KEGG   Felis catus (domestic cat): 101101082
Entry
101101082         CDS       T02385                                 
Symbol
GRK2
Name
(RefSeq) beta-adrenergic receptor kinase 1 isoform X1
  KO
K00910  beta-adrenergic-receptor kinase [EC:2.7.11.15]
Organism
fca  Felis catus (domestic cat)
Pathway
fca04062  Chemokine signaling pathway
fca04144  Endocytosis
fca04340  Hedgehog signaling pathway
fca04724  Glutamatergic synapse
fca04740  Olfactory transduction
fca05032  Morphine addiction
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04340 Hedgehog signaling pathway
    101101082 (GRK2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    101101082 (GRK2)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    101101082 (GRK2)
  09156 Nervous system
   04724 Glutamatergic synapse
    101101082 (GRK2)
  09157 Sensory system
   04740 Olfactory transduction
    101101082 (GRK2)
 09160 Human Diseases
  09165 Substance dependence
   05032 Morphine addiction
    101101082 (GRK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:fca01001]
    101101082 (GRK2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    101101082 (GRK2)
Enzymes [BR:fca01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.15  beta-adrenergic-receptor kinase
     101101082 (GRK2)
Protein kinases [BR:fca01001]
 Serine/threonine kinases: AGC group
  GRK family [OT]
   101101082 (GRK2)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101101082 (GRK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr RGS PH Kinase-like DUF5647 Haspin_kinase
Other DBs
NCBI-GeneID: 101101082
NCBI-ProteinID: XP_023095872
EnsemblRapid: ENSFCTG00005017005
Position
D1:109933338..109952746
AA seq 689 aa
MADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFS
QKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLARSREVFDTYIMKELLAC
SHPFSKSATEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNV
ELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNER
IMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAE
IILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPE
VLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPE
LRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGEVNAA
DAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARK
KTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSL
LTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQR
VPKMKNKPRSPVVELSKVPLVQRGSANGL
NT seq 2070 nt   +upstreamnt  +downstreamnt
atggcggacctggaggcggtgctggccgatgtgagctacctgatggccatggagaagagc
aaggccacgccggccgcgcgcgccagcaagaagatcctgctgcccgaacccagcatccga
agcgtcatgcagaagtacctggaagaccggggcgaggtgacctttgagaagatcttctcc
cagaagctggggtacctgctcttccgagacttctgcctgaaacacctagaggaggccaag
ccgttggtggagttctatgaggagatcaagaaatacgagaagctggagacggaggaggag
cgcttggctcgcagccgggaggtcttcgacacctacatcatgaaggagctgctggcctgc
tcacaccccttctcgaaaagtgccactgagcacgtccagggccacctggtgaagaagcag
gttcctccggatctcttccagccatacattgaagagatttgtcagaacctccgaggggat
gtgttccagaaattcatcgagagcgataaattcacacgattttgccagtggaagaatgtg
gagctcaacatccatctgaccatgaacgacttcagcgtgcaccgcatcatcggacgaggg
ggcttcggcgaggtctatgggtgccggaaggccgacacgggcaagatgtacgccatgaag
tgtctggataagaagcgcatcaagatgaagcagggggagaccctggccctgaacgagcgc
atcatgctgtccctcgtcagcactggggactgcccgttcatcgtgtgcatgtcgtacgca
ttccacacgccggacaagctcagcttcatccttgatctcatgaacggcggggacctgcac
taccacctgtcccagcacggggttttctccgaggccgacatgcgcttctacgcggccgag
atcatcctgggcctggagcacatgcacaaccgcttcgttgtctatcgggacctgaagcca
gccaacatccttctggacgagcacggtcacgtgcgcatctcggacctcggcctggcctgc
gacttctccaagaagaagccccacgccagcgtgggcacccacgggtacatggcccctgag
gtcctgcagaagggcgtggcctacgatagcagcgctgactggttctccctgggctgcatg
cttttcaagttgctgcgggggcacagcccctttcggcagcacaagaccaaagataagcac
gagattgaccgcatgacattgacaatggctgtggagctgcccgactccttctcccccgag
ctccgttccttgctggaggggctgctgcagagggatgtcaaccggagactgggctgcctg
ggtcgaggggcccaggaggtaaaggagagccccttcttccgctccttggactggcagatg
gtcttcttgcagaagtaccctcccccgctgatcccccctcgaggggaggtgaacgctgct
gacgccttcgacattggctcctttgacgaggaggacacaaaaggaatcaagttgctggac
agtgaccaggaactctaccgcaacttccccctcaccatctcggagcggtggcagcaggag
gtggccgagacggtcttcgacaccatcaatgccgagactgaccggctggaggcccgcaag
aaaaccaaaaacaagcagttgggccacgaggaagactatgccctgggcaaggactgcatc
atgcatggctacatgtccaagatgggcaaccccttcctgacgcagtggcagaggcggtac
ttctacttgtttcccaaccggctggagtggcggggcgagggcgaggccccgcagagcctg
ctgaccatggaggagatccagtctgtggaggagacgcagatcaaggagcggaagtgcctc
cttctcaagatccgcggcggcaaacagtttgtgctgcagtgcgacagtgaccctgagctg
gtgcagtggaagaaggagcttcgtgacgcgtaccgcgaggcccagcagctggtgcagcgc
gtgcccaagatgaagaacaagccgcgctcgcccgtggtggagctgagcaaggtgccgctg
gtccagcgcggcagtgccaacggcctctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (32)   

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