KEGG   Felis catus (domestic cat): 101101375
Entry
101101375         CDS       T02385                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
fca  Felis catus (domestic cat)
Pathway
fca00230  Purine metabolism
fca01100  Metabolic pathways
fca01522  Endocrine resistance
fca04015  Rap1 signaling pathway
fca04020  Calcium signaling pathway
fca04022  cGMP-PKG signaling pathway
fca04024  cAMP signaling pathway
fca04062  Chemokine signaling pathway
fca04072  Phospholipase D signaling pathway
fca04114  Oocyte meiosis
fca04211  Longevity regulating pathway
fca04213  Longevity regulating pathway - multiple species
fca04261  Adrenergic signaling in cardiomyocytes
fca04270  Vascular smooth muscle contraction
fca04371  Apelin signaling pathway
fca04540  Gap junction
fca04611  Platelet activation
fca04713  Circadian entrainment
fca04714  Thermogenesis
fca04720  Long-term potentiation
fca04723  Retrograde endocannabinoid signaling
fca04724  Glutamatergic synapse
fca04725  Cholinergic synapse
fca04727  GABAergic synapse
fca04750  Inflammatory mediator regulation of TRP channels
fca04911  Insulin secretion
fca04912  GnRH signaling pathway
fca04913  Ovarian steroidogenesis
fca04914  Progesterone-mediated oocyte maturation
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04918  Thyroid hormone synthesis
fca04921  Oxytocin signaling pathway
fca04923  Regulation of lipolysis in adipocytes
fca04925  Aldosterone synthesis and secretion
fca04926  Relaxin signaling pathway
fca04927  Cortisol synthesis and secretion
fca04928  Parathyroid hormone synthesis, secretion and action
fca04934  Cushing syndrome
fca04935  Growth hormone synthesis, secretion and action
fca04970  Salivary secretion
fca04971  Gastric acid secretion
fca04972  Pancreatic secretion
fca04976  Bile secretion
fca05032  Morphine addiction
fca05142  Chagas disease
fca05146  Amoebiasis
fca05163  Human cytomegalovirus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05200  Pathways in cancer
fca05207  Chemical carcinogenesis - receptor activation
fca05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:fca00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101101375 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101101375 (ADCY1)
   04371 Apelin signaling pathway
    101101375 (ADCY1)
   04020 Calcium signaling pathway
    101101375 (ADCY1)
   04072 Phospholipase D signaling pathway
    101101375 (ADCY1)
   04024 cAMP signaling pathway
    101101375 (ADCY1)
   04022 cGMP-PKG signaling pathway
    101101375 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101101375 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101101375 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101101375 (ADCY1)
   04062 Chemokine signaling pathway
    101101375 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    101101375 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    101101375 (ADCY1)
   04912 GnRH signaling pathway
    101101375 (ADCY1)
   04913 Ovarian steroidogenesis
    101101375 (ADCY1)
   04915 Estrogen signaling pathway
    101101375 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    101101375 (ADCY1)
   04921 Oxytocin signaling pathway
    101101375 (ADCY1)
   04926 Relaxin signaling pathway
    101101375 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    101101375 (ADCY1)
   04918 Thyroid hormone synthesis
    101101375 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    101101375 (ADCY1)
   04916 Melanogenesis
    101101375 (ADCY1)
   04925 Aldosterone synthesis and secretion
    101101375 (ADCY1)
   04927 Cortisol synthesis and secretion
    101101375 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101101375 (ADCY1)
   04270 Vascular smooth muscle contraction
    101101375 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    101101375 (ADCY1)
   04971 Gastric acid secretion
    101101375 (ADCY1)
   04972 Pancreatic secretion
    101101375 (ADCY1)
   04976 Bile secretion
    101101375 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    101101375 (ADCY1)
   04727 GABAergic synapse
    101101375 (ADCY1)
   04725 Cholinergic synapse
    101101375 (ADCY1)
   04720 Long-term potentiation
    101101375 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    101101375 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101101375 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    101101375 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    101101375 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101101375 (ADCY1)
   04714 Thermogenesis
    101101375 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101101375 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    101101375 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101101375 (ADCY1)
   05163 Human cytomegalovirus infection
    101101375 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    101101375 (ADCY1)
   05142 Chagas disease
    101101375 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    101101375 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101101375 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101101375 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101101375 (ADCY1)
Enzymes [BR:fca01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101101375 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6688
Other DBs
NCBI-GeneID: 101101375
NCBI-ProteinID: XP_006929124
EnsemblRapid: ENSFCTG00005009074
Position
A2:62038742..62150888
AA seq 1132 aa
MAGAPRGRGGGGGGGGGGAGEPGGAERAARPGGRRGLRACDEEFACPELEALFRGYTLRL
EQAATLKALAVLSGLAGALALAELLGAPGPAAGLARGSHPAHCVLFLALLVVTNVRSLQV
PQLQQVGQLALLFSLTFALLCCPFALGRPAGTLAGAASGPATADQGVWQLLLVTFVSYAL
LPVRSLLAIGFGLVVAASHLLVTATLVPAKRPRLWRTLGANALLFLSVNMYGVFVRILAE
RSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYI
QRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYC
VSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQY
DVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSFLKAHNIETFFI
VPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVLTCEDDDKR
RALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQTELEMADLDFFTLKYKQAE
RERKYHQLQDEYFTSAVVLALVLAALFGLVYLLIIPQNLVLLLLLAFCICFLVACVLYLH
VTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNGSLVVLTPSGRN
AVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYILVLELSGYTRAP
GGGVASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERDDMERVKLDNKR
ILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIELDGNNMGVECLR
LLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGISSHLSTLADFA
IEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQ
GRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQARERKVCGYGR
AGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHGQHLPPGAAGKEA
NT seq 3399 nt   +upstreamnt  +downstreamnt
atggcgggggcgccgcgcggccgaggcggaggcggcggcggaggcggaggcggcgcgggc
gagcccgggggcgcggagcgggcggcccggccgggcggccggcgcgggctgcgggcgtgc
gacgaggagttcgcgtgccccgagctggaggcgctgttccgcggctacacgctgcggctg
gagcaggcggctacgctgaaggcgctggcggtgctcagcgggctggcgggcgcgctggcg
ctggccgagctgctgggcgcgccggggcccgcggccggcctggcccggggctcgcacccc
gcgcactgcgtgctcttcctggcgctgctcgtggtcaccaacgtgcgctcgctgcaggtg
ccccagctgcagcaggtcggccagctggcgctgctcttcagcctcaccttcgcgctgctg
tgctgccccttcgcgctcggccgccccgcggggaccctcgccggcgccgcttcggggccg
gcgaccgccgaccagggcgtgtggcagctcctgctggtcaccttcgtgtcctatgccctg
ctgcccgtgcgcagcctgctggccatcggcttcgggctcgtggtggccgcctcgcacttg
ctggtcacggccaccttggtacccgccaagcgcccgcgtctctggaggacgcttggtgcc
aacgccctgctcttcctcagcgtgaacatgtatggggtgtttgtgcgcatcctggctgag
cgctcccagcggaaagccttcctgcaagcccggaactgcatcgaagatcggctgaggctg
gaggatgagaacgagaagcaggagcggctgctcatgagccttctgccccggaatgttgcc
atggagatgaaggaggacttcctgaagccccccgagaggattttccacaagatttacatc
cagcggcatgacaacgtgagcatcctctttgcggacattgtgggcttcacgggcctggca
tcgcagtgcacggcacaggagctggtgaagctcctcaacgagctgttcggcaagtttgat
gaactggccacggagaatcactgtcgccgcatcaagatcctaggggactgttactactgt
gtgtctggcctcacccagcccaagaccgaccacgcccactgctgcgtggagatgggcctg
gacatgatcgacaccatcacgtctgtggccgaggccaccgaggtggacctgaacatgcgc
gtggggctgcacacaggcagggtcctctgcggggtcctgggcctgcgcaagtggcagtac
gacgtgtggtccaacgacgtgactctggccaacgtcatggaggcagccggcctacctggg
aaggtccacatcacgaagacgaccctagcgtgcctgaacggggactacgaggtggagccg
ggtcacggacatgagaggaacagttttctgaaagctcacaacatcgagaccttctttatc
gtgccgtcacatcggcggaagatatttccagggctgatcctctctgacataaaaccagcc
aagaggatgaagttcaagaccgtgtgctacctgctcgtgcagctgatgcactgtcggaag
atgttcaaggcagagatcccgttctctaacgtcctgacgtgtgaggacgacgacaagcgg
agggcgctgagaaccgcgtcggagaaactgcgaaaccgctcttcgttctccgcaaacgcc
gtctacaccaccccgggcacgcgcgtcaacaggtacatcggccgcctcctggaagcgcgc
cagacggagctggagatggcggacttggacttcttcaccctcaagtacaagcaggctgag
cgggagcgcaagtaccaccagctccaggacgagtattttaccagcgccgtcgttctggcc
ctcgtcctggccgccttgttcggcctcgtctacctgctcatcatcccacagaacctggtc
ctcctgctgctgctggccttctgtatctgcttcctggtggcctgcgtcttgtacctgcac
gtcacccgggtccagtgttttccagggtgcctgacgattcagatccgtaccgtcttgtgt
atcttcgtcgtggtcttaatctactccgtggcccaaggatgtgtggtgggctgcctgccc
tggtcctggagctccacccccaacgggtccctggtggtcctgacgcccagcggccgcaac
gccgtgctgcctgccgcgccctgtgagtcggcgccccacgccctgctctgcggccttgtg
ggtaccctcccgctggctgtcttcctgcgggtgtcctccctgcccaaaatgatcctgctc
tttgtgctcacgacgtcctacatcctggtcctggagctcagcggctacaccagggccccc
gggggcggcgtggcgtcggggcgcagtttcgagccgatcatggccatcctgctgttttcc
tgcaccctggccctgcacgcccgtcaggtggacgtcaagctgcggctggactacctctgg
gcagcacaggcagaggaggagagagatgacatggagagggtgaagttggacaacaagagg
attctcttcaacctcctgccggcccacgtggctcagcacttcctcatgtccaacccccgc
aacatggacctgtactaccagtcctactcacaggtgggcgtcatgtttgcttccatcccc
aacttcgacgacttctacatcgagctggacggcaacaacatgggggtggagtgtctgcgt
ctcctgaacgagatcatcgcagacttcgacgagctcatggacaaagacttttacaaggac
ttggagaagatcaagaccatcgggagcacctacatggccgctgtggggctggcgcccacc
actgggaccaaggccaagaagggcatctcctcccacctgagcacactggctgacttcgcc
atcgagatgttcgacgtcctggatgaaatcaactaccagtcttacaacgactttgtgctc
cgtgtgggcatcaacgtaggccctgtggtggccggggtgatcggggctcggaggccgcag
tacgacatctgggggaacacagtcaacgtggccagtcggatggacagcaccggcgtccag
ggcagaatccaggtgactgaggaggttcaccggctgctgcgccgggggacctaccgcttc
gtgtgccgcgggaaggtcagcgtcaagggcaagggtgagatgctgacgtacttcctggaa
ggcaggacggatggaaacggctcccaagccagggagcggaaagtgtgtggctacgggcga
gccggcctccagggcagactgggcacgggcccacccccggtgtcctccatggccggcctc
ccggtcagagccgggatgggggctctgcagggctcagggctccccccctgcccccacggc
cagcacctgccccccggagcagctgggaaggaggcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (52)   
   KEGG PATHWAY (52)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   ENSEMBLRAPID (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (89)   

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