KEGG   Felis catus (domestic cat): 751103Help
Entry
751103            CDS       T02385                                 

Gene name
HRAS
Definition
(RefSeq) GTPase HRas isoform X1
  KO
K02833  GTPase HRas
Organism
fca  Felis catus (domestic cat)
Pathway
fca01521  EGFR tyrosine kinase inhibitor resistance
fca01522  Endocrine resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04014  Ras signaling pathway
fca04015  Rap1 signaling pathway
fca04062  Chemokine signaling pathway
fca04068  FoxO signaling pathway
fca04071  Sphingolipid signaling pathway
fca04072  Phospholipase D signaling pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04144  Endocytosis
fca04150  mTOR signaling pathway
fca04151  PI3K-Akt signaling pathway
fca04210  Apoptosis
fca04211  Longevity regulating pathway
fca04213  Longevity regulating pathway - multiple species
fca04218  Cellular senescence
fca04360  Axon guidance
fca04370  VEGF signaling pathway
fca04371  Apelin signaling pathway
fca04510  Focal adhesion
fca04540  Gap junction
fca04550  Signaling pathways regulating pluripotency of stem cells
fca04625  C-type lectin receptor signaling pathway
fca04630  Jak-STAT signaling pathway
fca04650  Natural killer cell mediated cytotoxicity
fca04660  T cell receptor signaling pathway
fca04662  B cell receptor signaling pathway
fca04664  Fc epsilon RI signaling pathway
fca04714  Thermogenesis
fca04720  Long-term potentiation
fca04722  Neurotrophin signaling pathway
fca04725  Cholinergic synapse
fca04726  Serotonergic synapse
fca04730  Long-term depression
fca04810  Regulation of actin cytoskeleton
fca04910  Insulin signaling pathway
fca04912  GnRH signaling pathway
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04917  Prolactin signaling pathway
fca04919  Thyroid hormone signaling pathway
fca04921  Oxytocin signaling pathway
fca04926  Relaxin signaling pathway
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca05034  Alcoholism
fca05160  Hepatitis C
fca05161  Hepatitis B
fca05163  Human cytomegalovirus infection
fca05165  Human papillomavirus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05170  Human immunodeficiency virus 1 infection
fca05200  Pathways in cancer
fca05203  Viral carcinogenesis
fca05205  Proteoglycans in cancer
fca05206  MicroRNAs in cancer
fca05210  Colorectal cancer
fca05211  Renal cell carcinoma
fca05213  Endometrial cancer
fca05214  Glioma
fca05215  Prostate cancer
fca05216  Thyroid cancer
fca05218  Melanoma
fca05219  Bladder cancer
fca05220  Chronic myeloid leukemia
fca05221  Acute myeloid leukemia
fca05223  Non-small cell lung cancer
fca05224  Breast cancer
fca05225  Hepatocellular carcinoma
fca05226  Gastric cancer
fca05230  Central carbon metabolism in cancer
fca05231  Choline metabolism in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    751103 (HRAS)
   04015 Rap1 signaling pathway
    751103 (HRAS)
   04010 MAPK signaling pathway
    751103 (HRAS)
   04012 ErbB signaling pathway
    751103 (HRAS)
   04370 VEGF signaling pathway
    751103 (HRAS)
   04371 Apelin signaling pathway
    751103 (HRAS)
   04630 Jak-STAT signaling pathway
    751103 (HRAS)
   04068 FoxO signaling pathway
    751103 (HRAS)
   04072 Phospholipase D signaling pathway
    751103 (HRAS)
   04071 Sphingolipid signaling pathway
    751103 (HRAS)
   04151 PI3K-Akt signaling pathway
    751103 (HRAS)
   04150 mTOR signaling pathway
    751103 (HRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    751103 (HRAS)
   04140 Autophagy - animal
    751103 (HRAS)
   04137 Mitophagy - animal
    751103 (HRAS)
  09143 Cell growth and death
   04210 Apoptosis
    751103 (HRAS)
   04218 Cellular senescence
    751103 (HRAS)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    751103 (HRAS)
   04540 Gap junction
    751103 (HRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    751103 (HRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    751103 (HRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    751103 (HRAS)
   04650 Natural killer cell mediated cytotoxicity
    751103 (HRAS)
   04660 T cell receptor signaling pathway
    751103 (HRAS)
   04662 B cell receptor signaling pathway
    751103 (HRAS)
   04664 Fc epsilon RI signaling pathway
    751103 (HRAS)
   04062 Chemokine signaling pathway
    751103 (HRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    751103 (HRAS)
   04912 GnRH signaling pathway
    751103 (HRAS)
   04915 Estrogen signaling pathway
    751103 (HRAS)
   04917 Prolactin signaling pathway
    751103 (HRAS)
   04921 Oxytocin signaling pathway
    751103 (HRAS)
   04926 Relaxin signaling pathway
    751103 (HRAS)
   04919 Thyroid hormone signaling pathway
    751103 (HRAS)
   04916 Melanogenesis
    751103 (HRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    751103 (HRAS)
   04726 Serotonergic synapse
    751103 (HRAS)
   04720 Long-term potentiation
    751103 (HRAS)
   04730 Long-term depression
    751103 (HRAS)
   04722 Neurotrophin signaling pathway
    751103 (HRAS)
  09158 Development
   04360 Axon guidance
    751103 (HRAS)
  09149 Aging
   04211 Longevity regulating pathway
    751103 (HRAS)
   04213 Longevity regulating pathway - multiple species
    751103 (HRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    751103 (HRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    751103 (HRAS)
   05206 MicroRNAs in cancer
    751103 (HRAS)
   05205 Proteoglycans in cancer
    751103 (HRAS)
   05203 Viral carcinogenesis
    751103 (HRAS)
   05230 Central carbon metabolism in cancer
    751103 (HRAS)
   05231 Choline metabolism in cancer
    751103 (HRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    751103 (HRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    751103 (HRAS)
   05225 Hepatocellular carcinoma
    751103 (HRAS)
   05226 Gastric cancer
    751103 (HRAS)
   05214 Glioma
    751103 (HRAS)
   05216 Thyroid cancer
    751103 (HRAS)
   05221 Acute myeloid leukemia
    751103 (HRAS)
   05220 Chronic myeloid leukemia
    751103 (HRAS)
   05218 Melanoma
    751103 (HRAS)
   05211 Renal cell carcinoma
    751103 (HRAS)
   05219 Bladder cancer
    751103 (HRAS)
   05215 Prostate cancer
    751103 (HRAS)
   05213 Endometrial cancer
    751103 (HRAS)
   05224 Breast cancer
    751103 (HRAS)
   05223 Non-small cell lung cancer
    751103 (HRAS)
  09165 Substance dependence
   05034 Alcoholism
    751103 (HRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    751103 (HRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    751103 (HRAS)
   05170 Human immunodeficiency virus 1 infection
    751103 (HRAS)
   05161 Hepatitis B
    751103 (HRAS)
   05160 Hepatitis C
    751103 (HRAS)
   05163 Human cytomegalovirus infection
    751103 (HRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    751103 (HRAS)
   05165 Human papillomavirus infection
    751103 (HRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    751103 (HRAS)
   01522 Endocrine resistance
    751103 (HRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    751103 (HRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    751103 (HRAS)
   04031 GTP-binding proteins [BR:fca04031]
    751103 (HRAS)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    751103 (HRAS)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   751103 (HRAS)
  Exosomal proteins of colorectal cancer cells
   751103 (HRAS)
GTP-binding proteins [BR:fca04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [OT]
    751103 (HRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Gtr1_RagA ATP_bind_1 G-alpha Septin Ldh_1_N AAA_25 AAA_16
Motif
Other DBs
NCBI-GeneID: 751103
NCBI-ProteinID: XP_003993860
Ensembl: ENSFCAG00000002990
UniProt: M3WSA0
Position
D1
AA seq 189 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKVRKLSPPDEGGPG
CMSCKCLLS
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atgacggaatataagctcgtggtggtgggcgctggaggtgtggggaagagtgccctgacc
atccagctcatccagaaccacttcgtggatgagtatgaccccaccatcgaggactcctat
cggaagcaagtggttattgatggcgagacgtgcctactggacattttggacacggcgggc
caggaggagtatagcgccatgcgggaccagtacatgcgcactggagaaggcttcctctgt
gtgtttgccatcaacaataccaagtcctttgaggacatccaccagtacagggagcaaatc
aagcgagtgaaggactccgatgacgtgcccatggtgttggtggggaacaagtgcgacctg
gccgcgcgcaccgtggagtcccggcaggcgcaggacctcgcccgcagctacggcatcccg
tacatcgagacgtcggccaagactcgccagggtgtggaggacgctttctacacgctggtc
cgagagatccggcaacacaaggtgcggaagctgagcccgcccgacgagggtggccccggc
tgcatgagctgcaagtgcctgctctcctga

KEGG   Felis catus (domestic cat): 751104Help
Entry
751104            CDS       T02385                                 

Gene name
KRAS
Definition
(RefSeq) GTPase KRas
  KO
K07827  GTPase KRas
Organism
fca  Felis catus (domestic cat)
Pathway
fca01521  EGFR tyrosine kinase inhibitor resistance
fca01522  Endocrine resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04014  Ras signaling pathway
fca04015  Rap1 signaling pathway
fca04062  Chemokine signaling pathway
fca04068  FoxO signaling pathway
fca04071  Sphingolipid signaling pathway
fca04072  Phospholipase D signaling pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04150  mTOR signaling pathway
fca04151  PI3K-Akt signaling pathway
fca04210  Apoptosis
fca04211  Longevity regulating pathway
fca04213  Longevity regulating pathway - multiple species
fca04218  Cellular senescence
fca04360  Axon guidance
fca04370  VEGF signaling pathway
fca04371  Apelin signaling pathway
fca04540  Gap junction
fca04550  Signaling pathways regulating pluripotency of stem cells
fca04625  C-type lectin receptor signaling pathway
fca04650  Natural killer cell mediated cytotoxicity
fca04660  T cell receptor signaling pathway
fca04662  B cell receptor signaling pathway
fca04664  Fc epsilon RI signaling pathway
fca04714  Thermogenesis
fca04720  Long-term potentiation
fca04722  Neurotrophin signaling pathway
fca04725  Cholinergic synapse
fca04726  Serotonergic synapse
fca04730  Long-term depression
fca04810  Regulation of actin cytoskeleton
fca04910  Insulin signaling pathway
fca04912  GnRH signaling pathway
fca04914  Progesterone-mediated oocyte maturation
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04917  Prolactin signaling pathway
fca04919  Thyroid hormone signaling pathway
fca04921  Oxytocin signaling pathway
fca04926  Relaxin signaling pathway
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca04960  Aldosterone-regulated sodium reabsorption
fca05034  Alcoholism
fca05160  Hepatitis C
fca05161  Hepatitis B
fca05163  Human cytomegalovirus infection
fca05165  Human papillomavirus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05170  Human immunodeficiency virus 1 infection
fca05200  Pathways in cancer
fca05203  Viral carcinogenesis
fca05205  Proteoglycans in cancer
fca05206  MicroRNAs in cancer
fca05210  Colorectal cancer
fca05211  Renal cell carcinoma
fca05212  Pancreatic cancer
fca05213  Endometrial cancer
fca05214  Glioma
fca05215  Prostate cancer
fca05216  Thyroid cancer
fca05218  Melanoma
fca05219  Bladder cancer
fca05220  Chronic myeloid leukemia
fca05221  Acute myeloid leukemia
fca05223  Non-small cell lung cancer
fca05224  Breast cancer
fca05225  Hepatocellular carcinoma
fca05226  Gastric cancer
fca05230  Central carbon metabolism in cancer
fca05231  Choline metabolism in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    751104 (KRAS)
   04015 Rap1 signaling pathway
    751104 (KRAS)
   04010 MAPK signaling pathway
    751104 (KRAS)
   04012 ErbB signaling pathway
    751104 (KRAS)
   04370 VEGF signaling pathway
    751104 (KRAS)
   04371 Apelin signaling pathway
    751104 (KRAS)
   04068 FoxO signaling pathway
    751104 (KRAS)
   04072 Phospholipase D signaling pathway
    751104 (KRAS)
   04071 Sphingolipid signaling pathway
    751104 (KRAS)
   04151 PI3K-Akt signaling pathway
    751104 (KRAS)
   04150 mTOR signaling pathway
    751104 (KRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    751104 (KRAS)
   04137 Mitophagy - animal
    751104 (KRAS)
  09143 Cell growth and death
   04210 Apoptosis
    751104 (KRAS)
   04218 Cellular senescence
    751104 (KRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    751104 (KRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    751104 (KRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    751104 (KRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    751104 (KRAS)
   04650 Natural killer cell mediated cytotoxicity
    751104 (KRAS)
   04660 T cell receptor signaling pathway
    751104 (KRAS)
   04662 B cell receptor signaling pathway
    751104 (KRAS)
   04664 Fc epsilon RI signaling pathway
    751104 (KRAS)
   04062 Chemokine signaling pathway
    751104 (KRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    751104 (KRAS)
   04912 GnRH signaling pathway
    751104 (KRAS)
   04915 Estrogen signaling pathway
    751104 (KRAS)
   04914 Progesterone-mediated oocyte maturation
    751104 (KRAS)
   04917 Prolactin signaling pathway
    751104 (KRAS)
   04921 Oxytocin signaling pathway
    751104 (KRAS)
   04926 Relaxin signaling pathway
    751104 (KRAS)
   04919 Thyroid hormone signaling pathway
    751104 (KRAS)
   04916 Melanogenesis
    751104 (KRAS)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    751104 (KRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    751104 (KRAS)
   04726 Serotonergic synapse
    751104 (KRAS)
   04720 Long-term potentiation
    751104 (KRAS)
   04730 Long-term depression
    751104 (KRAS)
   04722 Neurotrophin signaling pathway
    751104 (KRAS)
  09158 Development
   04360 Axon guidance
    751104 (KRAS)
  09149 Aging
   04211 Longevity regulating pathway
    751104 (KRAS)
   04213 Longevity regulating pathway - multiple species
    751104 (KRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    751104 (KRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    751104 (KRAS)
   05206 MicroRNAs in cancer
    751104 (KRAS)
   05205 Proteoglycans in cancer
    751104 (KRAS)
   05203 Viral carcinogenesis
    751104 (KRAS)
   05230 Central carbon metabolism in cancer
    751104 (KRAS)
   05231 Choline metabolism in cancer
    751104 (KRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    751104 (KRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    751104 (KRAS)
   05212 Pancreatic cancer
    751104 (KRAS)
   05225 Hepatocellular carcinoma
    751104 (KRAS)
   05226 Gastric cancer
    751104 (KRAS)
   05214 Glioma
    751104 (KRAS)
   05216 Thyroid cancer
    751104 (KRAS)
   05221 Acute myeloid leukemia
    751104 (KRAS)
   05220 Chronic myeloid leukemia
    751104 (KRAS)
   05218 Melanoma
    751104 (KRAS)
   05211 Renal cell carcinoma
    751104 (KRAS)
   05219 Bladder cancer
    751104 (KRAS)
   05215 Prostate cancer
    751104 (KRAS)
   05213 Endometrial cancer
    751104 (KRAS)
   05224 Breast cancer
    751104 (KRAS)
   05223 Non-small cell lung cancer
    751104 (KRAS)
  09165 Substance dependence
   05034 Alcoholism
    751104 (KRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    751104 (KRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    751104 (KRAS)
   05170 Human immunodeficiency virus 1 infection
    751104 (KRAS)
   05161 Hepatitis B
    751104 (KRAS)
   05160 Hepatitis C
    751104 (KRAS)
   05163 Human cytomegalovirus infection
    751104 (KRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    751104 (KRAS)
   05165 Human papillomavirus infection
    751104 (KRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    751104 (KRAS)
   01522 Endocrine resistance
    751104 (KRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    751104 (KRAS)
  09183 Protein families: signaling and cellular processes
   04031 GTP-binding proteins [BR:fca04031]
    751104 (KRAS)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    751104 (KRAS)
GTP-binding proteins [BR:fca04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [OT]
    751104 (KRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 MeaB FeoB_N G-alpha ATP_bind_1 Septin AAA_25
Motif
Other DBs
NCBI-GeneID: 751104
NCBI-ProteinID: XP_023112621
Ensembl: ENSFCAG00000026808
Position
B4
AA seq 188 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDL
PSRTVDTKQAQDLARSYGIPFIETSAKTRQGVDDAFYTLVREIRKHKEKMSKDGKKKKKK
SKTKCIIM
NT seq 567 nt NT seq  +upstreamnt  +downstreamnt
atgactgaatataaacttgtggtagttggagctggtggcgtaggcaagagtgccttgacg
atacagctaattcagaatcactttgtggatgaatatgatcctacaatagaggattcctac
aggaaacaagtagtaattgatggagaaacctgtctcttggatattctcgacacagcaggt
caagaggagtacagtgcaatgagggaccagtacatgaggactggggagggctttctttgc
gtatttgccataaataatactaaatcatttgaagatattcaccactatagagaacaaata
aaaagagttaaagactctgaagatgtacctatggtcctagtaggaaataaatgtgatttg
ccttctagaacagtagatacaaaacaggctcaggacttagcaagaagttatggaattcct
tttattgaaacatcagcaaagacaagacagggtgttgacgatgccttctatacattagtt
cgagaaattcgaaaacataaagaaaagatgagcaaagatggtaaaaagaagaaaaagaag
tcaaagacaaagtgtataattatgtaa

KEGG   Felis catus (domestic cat): 751105Help
Entry
751105            CDS       T02385                                 

Gene name
NRAS
Definition
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
fca  Felis catus (domestic cat)
Pathway
fca01521  EGFR tyrosine kinase inhibitor resistance
fca01522  Endocrine resistance
fca04010  MAPK signaling pathway
fca04012  ErbB signaling pathway
fca04014  Ras signaling pathway
fca04015  Rap1 signaling pathway
fca04062  Chemokine signaling pathway
fca04068  FoxO signaling pathway
fca04071  Sphingolipid signaling pathway
fca04072  Phospholipase D signaling pathway
fca04137  Mitophagy - animal
fca04140  Autophagy - animal
fca04150  mTOR signaling pathway
fca04151  PI3K-Akt signaling pathway
fca04210  Apoptosis
fca04211  Longevity regulating pathway
fca04213  Longevity regulating pathway - multiple species
fca04218  Cellular senescence
fca04360  Axon guidance
fca04370  VEGF signaling pathway
fca04371  Apelin signaling pathway
fca04540  Gap junction
fca04550  Signaling pathways regulating pluripotency of stem cells
fca04625  C-type lectin receptor signaling pathway
fca04650  Natural killer cell mediated cytotoxicity
fca04660  T cell receptor signaling pathway
fca04662  B cell receptor signaling pathway
fca04664  Fc epsilon RI signaling pathway
fca04714  Thermogenesis
fca04720  Long-term potentiation
fca04722  Neurotrophin signaling pathway
fca04725  Cholinergic synapse
fca04726  Serotonergic synapse
fca04730  Long-term depression
fca04810  Regulation of actin cytoskeleton
fca04910  Insulin signaling pathway
fca04912  GnRH signaling pathway
fca04915  Estrogen signaling pathway
fca04916  Melanogenesis
fca04917  Prolactin signaling pathway
fca04919  Thyroid hormone signaling pathway
fca04921  Oxytocin signaling pathway
fca04926  Relaxin signaling pathway
fca04933  AGE-RAGE signaling pathway in diabetic complications
fca05034  Alcoholism
fca05160  Hepatitis C
fca05161  Hepatitis B
fca05163  Human cytomegalovirus infection
fca05165  Human papillomavirus infection
fca05166  Human T-cell leukemia virus 1 infection
fca05167  Kaposi sarcoma-associated herpesvirus infection
fca05170  Human immunodeficiency virus 1 infection
fca05200  Pathways in cancer
fca05203  Viral carcinogenesis
fca05205  Proteoglycans in cancer
fca05206  MicroRNAs in cancer
fca05210  Colorectal cancer
fca05211  Renal cell carcinoma
fca05213  Endometrial cancer
fca05214  Glioma
fca05215  Prostate cancer
fca05216  Thyroid cancer
fca05218  Melanoma
fca05219  Bladder cancer
fca05220  Chronic myeloid leukemia
fca05221  Acute myeloid leukemia
fca05223  Non-small cell lung cancer
fca05224  Breast cancer
fca05225  Hepatocellular carcinoma
fca05226  Gastric cancer
fca05230  Central carbon metabolism in cancer
fca05231  Choline metabolism in cancer
fca05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:fca00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    751105 (NRAS)
   04015 Rap1 signaling pathway
    751105 (NRAS)
   04010 MAPK signaling pathway
    751105 (NRAS)
   04012 ErbB signaling pathway
    751105 (NRAS)
   04370 VEGF signaling pathway
    751105 (NRAS)
   04371 Apelin signaling pathway
    751105 (NRAS)
   04068 FoxO signaling pathway
    751105 (NRAS)
   04072 Phospholipase D signaling pathway
    751105 (NRAS)
   04071 Sphingolipid signaling pathway
    751105 (NRAS)
   04151 PI3K-Akt signaling pathway
    751105 (NRAS)
   04150 mTOR signaling pathway
    751105 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    751105 (NRAS)
   04137 Mitophagy - animal
    751105 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    751105 (NRAS)
   04218 Cellular senescence
    751105 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    751105 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    751105 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    751105 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    751105 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    751105 (NRAS)
   04660 T cell receptor signaling pathway
    751105 (NRAS)
   04662 B cell receptor signaling pathway
    751105 (NRAS)
   04664 Fc epsilon RI signaling pathway
    751105 (NRAS)
   04062 Chemokine signaling pathway
    751105 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    751105 (NRAS)
   04912 GnRH signaling pathway
    751105 (NRAS)
   04915 Estrogen signaling pathway
    751105 (NRAS)
   04917 Prolactin signaling pathway
    751105 (NRAS)
   04921 Oxytocin signaling pathway
    751105 (NRAS)
   04926 Relaxin signaling pathway
    751105 (NRAS)
   04919 Thyroid hormone signaling pathway
    751105 (NRAS)
   04916 Melanogenesis
    751105 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    751105 (NRAS)
   04726 Serotonergic synapse
    751105 (NRAS)
   04720 Long-term potentiation
    751105 (NRAS)
   04730 Long-term depression
    751105 (NRAS)
   04722 Neurotrophin signaling pathway
    751105 (NRAS)
  09158 Development
   04360 Axon guidance
    751105 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    751105 (NRAS)
   04213 Longevity regulating pathway - multiple species
    751105 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    751105 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    751105 (NRAS)
   05206 MicroRNAs in cancer
    751105 (NRAS)
   05205 Proteoglycans in cancer
    751105 (NRAS)
   05203 Viral carcinogenesis
    751105 (NRAS)
   05230 Central carbon metabolism in cancer
    751105 (NRAS)
   05231 Choline metabolism in cancer
    751105 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    751105 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    751105 (NRAS)
   05225 Hepatocellular carcinoma
    751105 (NRAS)
   05226 Gastric cancer
    751105 (NRAS)
   05214 Glioma
    751105 (NRAS)
   05216 Thyroid cancer
    751105 (NRAS)
   05221 Acute myeloid leukemia
    751105 (NRAS)
   05220 Chronic myeloid leukemia
    751105 (NRAS)
   05218 Melanoma
    751105 (NRAS)
   05211 Renal cell carcinoma
    751105 (NRAS)
   05219 Bladder cancer
    751105 (NRAS)
   05215 Prostate cancer
    751105 (NRAS)
   05213 Endometrial cancer
    751105 (NRAS)
   05224 Breast cancer
    751105 (NRAS)
   05223 Non-small cell lung cancer
    751105 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    751105 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    751105 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    751105 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    751105 (NRAS)
   05161 Hepatitis B
    751105 (NRAS)
   05160 Hepatitis C
    751105 (NRAS)
   05163 Human cytomegalovirus infection
    751105 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    751105 (NRAS)
   05165 Human papillomavirus infection
    751105 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    751105 (NRAS)
   01522 Endocrine resistance
    751105 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:fca04131]
    751105 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:fca04147]
    751105 (NRAS)
   04031 GTP-binding proteins [BR:fca04031]
    751105 (NRAS)
Membrane trafficking [BR:fca04131]
 Endocytosis
  Macropinocytosis
   Ras GTPases
    751105 (NRAS)
Exosome [BR:fca04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   751105 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   751105 (NRAS)
  Exosomal proteins of breast cancer cells
   751105 (NRAS)
  Exosomal proteins of colorectal cancer cells
   751105 (NRAS)
GTP-binding proteins [BR:fca04031]
 Small (Monomeric) G-proteins
  Ras Family
   Ras [OT]
    751105 (NRAS)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ras Roc Arf GTP_EFTU RsgA_GTPase MMR_HSR1 FeoB_N Septin Ldh_1_N ParA AAA_25
Motif
Other DBs
NCBI-GeneID: 751105
NCBI-ProteinID: XP_019693224
Ensembl: ENSFCAG00000019026
UniProt: A0A2I2UNV5
Position
C1
AA seq 189 aa AA seqDB search
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt NT seq  +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca
atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac
cgaaaacaggtggttatagacggtgaaacctgtctgttggacatactggatacagctggt
caagaagagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaacaatagcaaatcatttgcagatattaacctttacagggaacagatt
aagcgagtaaaagactccgatgatgtacctatggtgctagtaggaaacaagtgtgatttg
ccaacaaggaccgtcgacacaaaacaagcccacgaactggccaagagttatgggattcca
ttcattgaaacctcagccaagaccagacagggtgttgaagatgccttttacacactggta
agagaaatacgtcagtaccgaatgaagaaactcaacagcagtgatgacgggactcaaggt
tgtatggggttaccgtgtgtggtgatgtaa

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