LOCUS FJ445118 7119 bp ss-RNA linear VRL 10-APR-2009
DEFINITION Human rhinovirus 18 strain ATCC VR-1128, complete genome.
ACCESSION FJ445118
VERSION FJ445118.1
DBLINK BioProject: PRJNA32533
KEYWORDS .
SOURCE rhinovirus A18 (HRV-A18)
ORGANISM rhinovirus A18
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Picornaviridae; Ensavirinae; Enterovirus;
Rhinovirus A.
REFERENCE 1 (bases 1 to 7119)
AUTHORS Palmenberg,A.C., Spiro,D., Kuzmickas,R., Wang,S., Djikeng,A.,
Rathe,J.A., Fraser-Liggett,C.M. and Liggett,S.B.
TITLE Sequencing and analyses of all known human rhinovirus genomes
reveal structure and evolution
JOURNAL Science 324 (5923), 55-59 (2009)
PUBMED 19213880
REFERENCE 2 (bases 1 to 7119)
AUTHORS Spiro,D., Kuzmickas,R., Palmenberg,A.C., Wang,S., Djikeng,A.,
Rathe,J.A., Overton,L., Tsitrin,T., Gallagher,T., Liu,J.,
Pushparaj,V., Tallon,L.J., Fraser-Liggett,C.M. and Liggett,S.B.
TITLE Direct Submission
JOURNAL Submitted (10-NOV-2008) University of Maryland School of Medicine,
20 Penn St, Baltimore, MD 21201, USA
FEATURES Location/Qualifiers
source 1..7119
/organism="rhinovirus A18"
/mol_type="genomic RNA"
/strain="ATCC VR-1128"
/culture_collection="ATCC:VR-1128"
/db_xref="taxon:147674"
/note="HRV18;
hrv-18"
CDS 612..7073
/codon_start=1
/product="polyprotein"
/protein_id="ACK37374.1"
/translation="MGAQVSRQNVGTHSTQNSVSNGSSLNYFNINYFKDAASHGASKL
DFSQDPSKFTDPVKDVLEKGIPTLQSPTVEACGYSDRIIQITRGDSTITSQDVANAVV
GYGVWPHYLTPQDATAIDKPSRPDTSSNRFYTLESKTWDSSSKGWWWKLPDALKDMGI
FGENMYYHFLGRSGYTVHVQCNASKFHQGTLIVAMIPEHQLASAIGGNVTAGYKYTHP
GERGRVINVASRGDNEKQPSDDNWLNFDGTLLGNITIYPHQLINLRSNNSATIIVPYV
NAVPMDSMLRHNNWSLVIIPICQLEGDPPTIPITISISPMCAEFSGVRARSQGLPAML
TPGSGQFMTTDDFQSPCALPWFHPTKEISIPGQVRNLIELCQVDTLIPINNLQANITN
LDMYSVVLNREIDPAKEVFAIKVDIASQPLATTLIGEISSYYTHWTGSLRFSFLFCGS
ANTTLKLLVAYTPPGIAKPADRKAAMLGTHVVWDVGLQSTISMVVPWVSASHFRNTTP
DTYSLAGYITCWYQTNLIAPTNAPQTARMLCFVSACKDFCLRMARDTNLHTQSGTIEQ
NPVENYIDEVLNEVLVVPNVNESHAITSNSAPALDAAETGHTSNVQPEDMIETRYVQT
SQTRDEMSIESFLGRSGCIHISKLVVHYEDYNAETRNFVKWQINLQEMAQIRRKFEMF
TYVRFDSEITLVPSVAAKGDDIGHIVMQYMYVPPGAPIPKTRDDFAWQSGTNASIFWQ
HGQTYPRFSLPFLSIASAYYMFYDGYDGDQTSSRYGTVATNDMGTLCSRIVTDKHKNE
VEITTRIYHKAKHVKAWCPRPPRAVEYTHTHVTNYKPKEGREKTAIVPRARITMAGPS
DMYVHVGNLIYRNLHLFNSEMHDSILISYSSDLVIYRTNTTGDDYIPTCDCTDATYYC
KHKNRYYPIKVTSHDWYEIQESEYYPKHIQYNLLIGEGPCEPGDCGGKLLCKHGVIGI
ITAGGEGHVAFIDLRHFQCAEEQGITDYIHMLGEAFGTGFVDSVKDQINAINPINNIS
KKIIKWLLRIISAMVIIIRNSSDPQTIIATLTLIGCSGSPWRFLKEKFCKWTQLNYIH
KESDSWLKKFTEMCNAARGLEWIGNKISKFIEWMKSMLPQAQLKVKYLSELKKLSFLE
KQMEHLRVADSKTQEKIKHEIDTLHDLSCKFLPLYASEAKRIKILHNKCNTIIKQKKR
CEPVAVVIHGEPGTGKSMTTNFLARMITSDSDIYSLPPDPKYFDGYDQQSVVIMDDIM
QNPSGDDMTLFCQMVSSVTFIPPMADLPDKGKPFDSRFVLCSTNHNLLAPPTITSLPA
MNRRFFLDLDIIVCDKYKDSQGKLNVSAAFQLCDVNTKVGNARCCPFICGKAVIFRDR
NTCQTYTLSQVYNLILEEDRKRTRVVDVMAAIFQGPITLEGPPPAAISDLLQSVRTPE
VIKYCEENKWIIPAECKVERDLNIANTIITIIANIVSISGIIYVIYKLFCTLQGPYSG
EPKPKTKIPERRVVAQGPEEEFGRSLIKHNSCIVTTQNGKFTGLGIYDRTLIIPTHAD
PGKEVQIDGITTEVQDSYDLYNKDGVKLEITVLKLKRNEKFKDIRKYIPEDEDDYPDC
NLALSANQPETTIINVGDVVSYGNILLSGNQTARMLKYNYPTKSGYCGGILYKIGQVL
GIHVGGNGRDGFAAMLLRSYFSETQGQIVSSKSTAECNYPSIHTPSKTKLQPSVFYDI
FPGNKEPAVLSEQDPRLKVDFKEALFSKYKGNNPCEINEHIKVAVSHYSAQLMTLDID
PSPISLEDGVFGMEGLEALDLNTSAGFPYVSMGIRKRDLINKQTKDITKLKLALDKYG
VDLPMVTFLKDELRKKEKISAGKTRVIEASSVNDTVLFRTTFGNLFSKFHLNPGIVTG
SAVGCDPETFWSKIPVMLDGECIMAFDYTNYDGSIHPIWFQALKEVLSNLGFNPNLID
RLCKSKHIFKNIYYEVEGGVPSGCSGTSIFNTMINNIIIRTLVLDAYKNIDLDKLKII
AYGDDVIFSYKYQLDMEAIAKEGTKYGLTITPADKSSEFKQLDYSNVTFLKRGFRQDD
KYQFLIHPTFPIEEIHESIRWTKKPSQMQEHVLSLCHLMWHNGKNVYKQFEQRIRSVS
AGRALYIPPYELLLHEWYEKF"
mat_peptide 612..818
/product="1A"
/note="VP4"
mat_peptide 819..1595
/product="1B"
/note="VP2"
mat_peptide 1596..2309
/product="1C"
/note="VP3"
mat_peptide 2310..3170
/product="1D"
/note="VP1"
mat_peptide 3171..3596
/product="2A"
/note="P2-A"
mat_peptide 3597..3881
/product="2B"
/note="P2-B"
mat_peptide 3882..4847
/product="2C"
/note="P-2C"
mat_peptide 4848..5078
/product="3A"
/note="P3-A"
mat_peptide 5079..5141
/product="3B"
/note="VPg"
mat_peptide 5142..5690
/product="3C"
/note="P3-C"
mat_peptide 5691..7070
/product="3D"
/note="polymerase"
ORIGIN
1 ttaaaactga atccaggttg ttcccacctg gatttcccat gtggagtagt acactgttat
61 tccggtaact ttgtacgcca gttttataac cccttcccct tatgtaactt agaagataag
121 cacaaagacc aataggtggt ggctatccca gtcactaaag gtcaagcact tctgtttccc
181 cggtcaacgt tgatatgctc caccagggca aaaacaaccg agatcgttat ccgcaaagtg
241 cctacgcaaa gcctagtagc actttgaata gcatgtggtt ggtcgctcca ctattcccca
301 tagtagacct ggcagatgag gctagaaatc ccccactggc gacagtgttc tagcctgcgt
361 ggctgcctgc gtgtcctaac ggacacgaag ccatatgttt gacaaggtgt gaagagcccc
421 gtgtgctcac tttgagtcct ccggcccccg aatgtggcta accttaaccc tgcagctggg
481 gcatacaatc cagtgtgaac tcagtcgtaa tgagcaattg cgggatggga ccaactactt
541 tgggtgtccg tgtttcactt ttttttataa tgcttatggt gacaatatat aataatttgt
601 atattggcac catgggcgca caagtatcca gacagaacgt tggtacacac tctactcaaa
661 attcagtttc gaatggctca agtttgaatt attttaacat caactatttc aaggatgccg
721 catcgcatgg tgcctcaaaa ttagatttct ctcaagatcc aagtaaattc actgacccag
781 ttaaggatgt gttagaaaag ggtattccca cgcttcagtc tccaactgtt gaggcgtgtg
841 gatattctga tagaatcatt caaataacca gaggagactc tacaatcact tcccaggatg
901 tggcaaatgc agtggttggg tatggagttt ggccccacta cttgacacca caagatgcta
961 cagcaattga taaaccatca agacctgaca cttcatccaa tagattctat acactggaga
1021 gtaaaacttg ggatagttca tctaagggat ggtggtggaa acttccagat gcacttaaag
1081 acatgggcat atttggtgag aacatgtatt accatttctt gggaagaagt ggttatacag
1141 tacatgtcca atgcaatgct agtaaatttc atcagggcac actgattgta gcaatgatac
1201 cagagcatca actggccagt gcaattggag ggaacgttac tgctggatac aaatacaccc
1261 atcctggaga aagaggtaga gtcattaatg tagcaagtcg tggagacaat gaaaaacagc
1321 ctagtgatga caattggctc aactttgatg gaacattatt aggcaatatc acaatatacc
1381 cacatcaact tatcaactta agaagtaaca attcagccac aatcatagtg ccttatgtta
1441 atgctgtacc aatggattca atgctcagac ataacaattg gagtctggtg attataccca
1501 tatgtcaatt agagggagat ccaccaacaa taccaataac catctccatt agtcctatgt
1561 gtgctgagtt ttcaggagtc cgtgctcgta gccaaggtct accagccatg ctaacccctg
1621 ggtctggaca atttatgacc acagatgatt tccaatcccc ttgtgcttta ccttggttcc
1681 atcctactaa agagatatct ataccaggcc aggttaggaa cttaattgag ttgtgtcaag
1741 tggacacttt gattccgata aacaacttgc aagcaaatat tacaaattta gacatgtact
1801 cagtggtttt aaatagagaa atagacccag caaaggaagt ctttgcaata aaagttgaca
1861 ttgcctccca gccattagcc actacattaa ttggagagat atcaagctat tatacccatt
1921 ggactggcag tcttaggttt agtttcctat tctgtggttc agctaatacc acacttaaac
1981 tcctagtggc atacacacca ccaggaattg ccaaaccagc agataggaag gcagccatgc
2041 taggaactca tgttgtttgg gatgttggat tacaatccac tatctctatg gttgtgccat
2101 gggttagtgc tagtcatttt agaaacacaa cccctgatac atattcgctg gctggataca
2161 taacatgctg gtaccaaaca aaccttattg ctccaacaaa tgccccacaa actgcaagaa
2221 tgctgtgttt tgtctcagcc tgtaaggatt tttgcttaag aatggcacgt gacactaatc
2281 tgcacacaca atctggcact attgaacaaa atccagtaga gaattatata gatgaagtac
2341 ttaatgaagt gttagtggtc ccaaatgtga atgaaagtca cgcaattaca tcaaattcag
2401 cccctgcttt agatgccgct gaaactggtc acaccagcaa tgtgcaacct gaagatatga
2461 ttgagactag gtatgtacaa acatcacaaa caagagatga aatgagtata gagagttttc
2521 taggcagatc agggtgtata catatctcca agttagttgt acattatgaa gattataatg
2581 cagaaacaag gaactttgta aaatggcaaa taaatctaca ggaaatggcc cagattagga
2641 gaaaatttga gatgtttaca tatgttagat ttgattcaga aattacacta gtaccatctg
2701 tagctgctaa gggtgatgac ataggacata ttgttatgca gtacatgtat gttcctccag
2761 gagcaccaat accaaaaacc agagatgatt ttgcctggca atctggaaca aatgcatcaa
2821 tcttctggca acatggtcaa acatacccca gattttcact tcctttcctc agtatagcat
2881 cagcttatta catgttctat gatggctacg acggtgacca gacctcatcg cggtatggca
2941 cagttgcaac aaatgacatg ggtaccttgt gctctagaat agtcacagat aaacataaga
3001 atgaggtgga aataacaacc agaatatacc acaaggcaaa acatgttaaa gcatggtgcc
3061 caaggccacc gagagctgtg gagtacacac atacacatgt aactaactac aagcctaagg
3121 aaggaagaga gaaaactgcc atagtaccca gagcaaggat tacaatggct gggcctagtg
3181 acatgtatgt acatgtaggt aacctcatat atagaaattt acatttgttt aactcagaaa
3241 tgcatgactc aattctaatc tcatactcat cagatttagt catataccga acaaacacaa
3301 caggtgatga ctacattcca acatgtgatt gcacagatgc tacttattac tgcaagcaca
3361 agaatagata ctatccaatt aaagttacta gtcatgattg gtatgaaata caagagagtg
3421 agtactaccc aaaacatatc caatacaatt tactgattgg agagggccca tgtgaaccag
3481 gtgattgtgg gggtaaacta ttatgcaaac atggtgtaat tggaataatc actgctggtg
3541 gagaggggca tgtggcattt atagatctta ggcattttca atgtgctgaa gagcaaggca
3601 taacagatta catccatatg cttggtgaag cgtttggcac aggttttgtt gacagtgtca
3661 aagatcaaat aaatgctatt aaccccatta acaacattag taaaaagata attaaatggt
3721 tacttagaat aatatcagca atggtcataa taattagaaa ttcatcagat ccacagacta
3781 taatagctac tttaacattg attggctgct caggttcccc ttggagattt cttaaagaga
3841 aattttgtaa atggacacag ttaaattaca tacacaagga atcagattca tggcttaaaa
3901 aatttactga gatgtgtaat gcagctagag gcctggagtg gattggcaac aagatatcaa
3961 aatttattga atggatgaaa tctatgttac cccaagccca attgaaagtt aaatacttga
4021 gtgaattaaa gaaattaagt ttcttggaga agcaaatgga acacctgcgg gtggctgatt
4081 ctaaaaccca ggagaaaatt aaacacgaga ttgacacatt gcatgattta tcttgtaaat
4141 ttctacccct ctatgctagt gaggcaaaaa gaattaagat cctacacaat aagtgtaaca
4201 caattattaa acaaaagaaa agatgtgaac cagtggctgt tgtcatacat ggtgaacctg
4261 gcactggaaa atcaatgact acaaacttct tagctagaat gataacaagt gatagtgata
4321 tctattcctt accacctgat cccaagtatt ttgatggtta tgatcaacaa agtgtagtca
4381 taatggatga tataatgcag aatccaagtg gtgatgacat gactctattt tgtcagatgg
4441 tctcgagtgt tacttttata ccaccaatgg cagatttgcc agataaggga aaaccatttg
4501 actctagatt tgtattatgt agcaccaatc ataacttatt agcaccacct actataacct
4561 ccttaccagc tatgaatagg agattctttc ttgatttaga tattatagta tgtgacaaat
4621 ataaagactc acaagggaaa ctaaatgtgt ctgcagcttt ccaactatgt gatgtgaata
4681 ctaaagtagg aaatgcccgc tgttgtcctt ttatttgtgg aaaggctgta atttttaggg
4741 acaggaatac atgccaaact tacaccttat cacaagtgta taacctaata ttggaggaag
4801 acagaaagcg gacgcgggtt gttgatgtca tggcagcaat atttcaaggt ccaataacac
4861 ttgagggtcc cccaccagca gctattagtg atttattaca atcagttaga acccctgaag
4921 taattaaata ttgtgaagaa aacaaatgga taatacctgc tgaatgtaag gtagaaagag
4981 atttgaatat agctaacact ataataacaa tcattgctaa cattgttagt atatctggta
5041 ttatttatgt catttacaaa ctcttctgta cactgcaagg accctattct ggtgaaccca
5101 aaccaaagac aaaaattcca gagagaagag tagtggcaca agggccagaa gaggaatttg
5161 gaagatcttt aattaagcac aactcatgca ttgtcactac acaaaatgga aaatttacag
5221 gcctaggcat atatgacaga acacttataa taccaacaca tgctgatcca ggtaaagagg
5281 tgcaaataga tggtatcaca actgaagtac aagattctta tgatttatac aacaaagatg
5341 gagtgaagct agaaattaca gttcttaaat taaaaagaaa tgagaaattt aaagacatca
5401 ggaaatacat tccagaagat gaggatgatt atccagattg taatttggct ttgtcagcaa
5461 accagccaga aaccaccatt atcaacgtgg gggatgtggt atcatatggt aacattttac
5521 ttagtggtaa ccaaacagca aggatgctca aatacaatta cccaacaaaa tcagggtatt
5581 gtggaggaat tctatacaaa attggccaag ttctgggcat tcatgttggt ggtaatggga
5641 gagatgggtt tgcagctatg ttacttagat catatttctc agaaactcaa ggccagatag
5701 tttcttccaa atccactgct gaatgcaatt atcctagcat acacacacca agcaagacta
5761 aattacaacc cagtgttttt tatgacatct tccctggcaa taaagaacct gctgtactct
5821 cagaacaaga tcctagattg aaagttgatt ttaaagaggc tttattctct aaatacaaag
5881 gaaataatcc atgtgagata aatgaacata ttaaggtagc agtctctcat tattcagcac
5941 aattaatgac attagatatt gatccaagtc ccatttcctt agaagatggt gttttcggta
6001 tggagggttt agaagcacta gaccttaata ccagtgcagg atttccctat gtttccatgg
6061 gcattagaaa aagagatcta atcaacaagc aaaccaaaga tattacaaaa ttaaagttag
6121 cactagacaa gtatggtgtc gaccttccca tggtcacatt ccttaaggat gagcttagga
6181 agaaagaaaa aatctctgct gggaagactc gagtcataga agccagtagt gtgaatgaca
6241 ctgtattatt taggacaact tttgggaatc ttttctcaaa atttcatttg aatcctggga
6301 ttgtaaccgg ctcagctgtg ggatgtgatc cagagacatt ttggtctaag ataccagtga
6361 tgttggatgg tgagtgtata atggcttttg attacacaaa ttatgatggg agcatacatc
6421 caatatggtt tcaagcactc aaagaagtac tgtctaatct ggggttcaat cctaatttaa
6481 ttgacagatt atgcaagtca aaacacattt ttaaaaatat ctattatgag gttgaaggag
6541 gagtgccatc tggatgttct ggaacaagca tattcaacac aatgattaac aacattatca
6601 ttagaacact agttttggat gcatacaaaa acattgattt ggataaatta aaaataatag
6661 catatgggga tgatgtcata ttctcatata agtaccaatt ggacatggaa gcaattgcta
6721 aggaaggtac caagtatggt cttaccataa ccccagctga caaatcaagt gaatttaagc
6781 aattagatta tagcaatgtg acctttttga agagaggatt tagacaagat gacaaatacc
6841 aattcttaat acacccaact tttccaattg aagaaataca tgagtccata cgatggacca
6901 agaaaccatc tcaaatgcag gaacatgtgt tgtcgttgtg tcatttaatg tggcataatg
6961 gcaaaaacgt gtacaagcag tttgaacaaa ggatacgcag tgtcagcgct ggacgtgcac
7021 tgtatatccc tccctacgaa ctgcttctgc atgaatggta cgaaaaattt tgaattgttt
7081 agatatagaa gtaataaaca attagttttt tagttttat
//
