LOCUS FM955841 7667 bp DNA circular VRL 22-JUL-2009
DEFINITION Human papillomavirus type 105, complete genome.
ACCESSION FM955841
VERSION FM955841.1
KEYWORDS complete genome.
SOURCE Human papillomavirus 105
ORGANISM Human papillomavirus 105
Viruses; Monodnaviria; Shotokuvirae; Cossaviricota;
Papovaviricetes; Zurhausenvirales; Papillomaviridae;
Firstpapillomavirinae; Betapapillomavirus; Betapapillomavirus 1.
REFERENCE 1
AUTHORS de Villiers,E.M. and Gunst,K.
TITLE Characterization of seven novel human papillomavirus types isolated
from cutaneous tissue, but also present in mucosal lesions
JOURNAL J. Gen. Virol. 90 (PT 8), 1999-2004 (2009)
PUBMED 19386784
REFERENCE 2 (bases 1 to 7667)
AUTHORS de Villiers,E.M.
TITLE Direct Submission
JOURNAL Submitted (03-JAN-2009) de Villiers E.M., Characterization of
Tumorviruses, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld
242, Heidelberg, 69120, GERMANY
FEATURES Location/Qualifiers
source 1..7667
/organism="Human papillomavirus 105"
/mol_type="genomic DNA"
/isolate="DL294"
/isolation_source="normal skin"
/db_xref="taxon:587350"
gene 190..657
/gene="E6"
CDS 190..657
/gene="E6"
/codon_start=1
/product="E6 protein"
/protein_id="CAW42259.1"
/db_xref="GOA:C4PUE7"
/db_xref="InterPro:IPR001334"
/db_xref="UniProtKB/TrEMBL:C4PUE7"
/translation="MERQTNQEATANQTLQLPTSIKELADLLEIPLVDCLIPCNFCGR
FLDYLELCEFDKKKLTLIWKDYFVTACCRSCCVATATFEFNEHYEQTVLGRDIELATG
LSIFEINIRCQTCLSFLDLIEKLDSCGGGLPFHKVRGGWKGICRHCKHLYNDW"
gene 647..952
/gene="E7"
CDS 647..952
/gene="E7"
/codon_start=1
/product="E7 protein"
/protein_id="CAW42261.1"
/db_xref="GOA:C4PUE8"
/db_xref="InterPro:IPR000148"
/db_xref="UniProtKB/TrEMBL:C4PUE8"
/translation="MIGKEVTVQDFVLELSEIQPEVLPVDLFCEEELPNEQEEELDIQ
KTVFKIIAPCGCSCCEVNLRIFVNATDVGIRTLQELLTSDLQLLCPECRGNCKHGGS"
gene 939..2750
/gene="E1"
CDS 939..2750
/gene="E1"
/codon_start=1
/product="E1 protein"
/protein_id="CAW42263.1"
/db_xref="GOA:C4PUE9"
/db_xref="InterPro:IPR001177"
/db_xref="InterPro:IPR014000"
/db_xref="InterPro:IPR014015"
/db_xref="InterPro:IPR016393"
/db_xref="UniProtKB/TrEMBL:C4PUE9"
/translation="MADPKGSTSKEGLSDWCLLEADCSDLENDFEQLCERDTDSDISD
LLDNCDLEQGNSLELFHQQECKESGEQLQKLKRKYLSPKAVAQLSPRLESISLSPQQK
SKRRLFAEQDSGLELSLNNEAEDVSPEVEVPAIDSRPVEGGSGDVDINYTALLRSSNH
RATLLSKFKDAFGVGFNELTRQFKSYKTCCNDWVVAVYAVHDDLFESSKQLLQQHCDY
IWVSGIGAMTLYLLCFKAGKNRGTVHKLTTSMLNVHEQQILSEPPKLRNTAAALFWYK
GCMGSGTFTYGPYPEWIAHQTILGHQNAEASTFDLSVMVQWAFDHNLVDEADIAYKYA
KLAPEDSNAVAWLAHNNQAKFVRECASMVRFYKKGQMKEMSMSEWIYTKINEVEGEGH
WSSIVKFLRYQGINFIMFLAALKDFLHAVPKKNCILIYGPPNSGKSSFAMSLIKVLKG
RVLSFVNSKSQFWLQPLSECKIALLDDVTDPCWLYMDKYLRNGLDGHFVSLDCKYKAP
MQTKFPPLLLTSNINVHAEVNYRYLHSRIKGFEFPNPFPMKSDNTPEFELTDQSWKSF
FERLWTQLELSDQEDEGENGESQRAFQCSARSANEHI"
gene 2692..4206
/gene="E2"
CDS 2692..4206
/gene="E2"
/codon_start=1
/product="E2 protein"
/protein_id="CAW42264.1"
/db_xref="GOA:C4PUF0"
/db_xref="InterPro:IPR000427"
/db_xref="InterPro:IPR001866"
/db_xref="InterPro:IPR009021"
/db_xref="InterPro:IPR012677"
/db_xref="UniProtKB/TrEMBL:C4PUF0"
/translation="MENLSERFNVLQDQLMNIYEAAEQTLEAQITHWTLLRKEAVLLH
FARQKGVTRLGYQPVPPLAVTEAKAKEAIGMMLQLQSLQKSEYASETWTLVDTSTETF
RSAPENHFKKGPVSVEVIYDKDPENANAYTMWNYVYYMDSDDVWHKTTSGVNQTGIYY
MHGNFKHYYVVFADDASRYSATGQWEVKVNKETVFAPVTSSTPPGSPGQTDTNASSTT
PTTTSDSASRHQQPQQTEAKGRQYGRRPSSRTRRQETQQRRRRSRSRYRSRSRSRSRS
RAKSQAGLRAIRATSISRSRSPSVTQTGSGSGLGPDLDPEPDSQPPLGEGEVEGHPGG
APNHPPPLPENGKKTEGRGEEGATGGAGDVGEDHLPPPPTPTPTKRRRTESVRVRGVS
PDEVGKSLHTVSARNRGELGRLLEEALDPPVILCRGEANTLKCFRNRAKKKYEGLFRA
FSTTWSWVAGDSIERLGRPRMLISFASDRQRKHFDVTVKYPKGVETSYGNLDSL"
gene 4290..5846
/gene="L2"
CDS 4290..5846
/gene="L2"
/codon_start=1
/product="L2 protein"
/protein_id="CAW42266.1"
/db_xref="GOA:C4PUF1"
/db_xref="InterPro:IPR000784"
/db_xref="UniProtKB/TrEMBL:C4PUF1"
/translation="MARAKRVKRDSVTHIYQTCKQAGTCPPDVLNKVEQTTVADNILK
YGSAGVFFGGLGISTGRGTGGITGYTPLGEGPGVCVGNTPTVVRPSLVPETVGPMNIL
PIDTLNPVEPTASSVVPLTESSASDLLPGEIETIAEIHPVPEGPVVDSPVVTTSKGSS
AILEVAPEPSPPTRVRVSRTQYHNPSFQSITESTPAQGESSLADHVLVTSGAGGQSIG
SEITDIIELQEFPSRYSFEIEEPTPPRRTSTPSQRPQVLGQRRGLSLTNRRLVQQVPV
DNSLFLTQPSKLVRFAFDNPVFEEEVTNIFEQDIDEFEEPPDRDFLDVRQLGRPQYST
TPAGYVRVSRLGTRGTIRTRSGAQIGSQVHFYRDLSSINTEDPIELQFLGQHSGDATI
VQGPVESTFIDVDMSENPLSETVDAGSEDFLLDEAVEDFSGSQLVIGNRRSTTSYTVP
RFETTRNSSYYVQDTKGYYVAYPESRDTAEIIYPTPDIPIVVIHTHDSSGDFYLHPSL
RKRKRKRKYL"
gene 5843..7405
/gene="L1"
CDS 5843..7405
/gene="L1"
/codon_start=1
/product="L1 protein"
/protein_id="CAW42268.1"
/db_xref="GOA:C4PUF2"
/db_xref="InterPro:IPR002210"
/db_xref="InterPro:IPR011222"
/db_xref="UniProtKB/TrEMBL:C4PUF2"
/translation="MILHSQMAVWQSAHGKVYLPPSTPVARVQSTDEYIQRTNIYYHA
NTDRPLTVGHPYFNVYNNTGETLQVPKVSGNQHRVFRLKLPDPNRFALADMSVYNPDK
ERLVWACRGLEISRGQPLGVGSTGHPYFNKLKDTENSNQYSTTSKDDRQNTSFDPKQI
QMFIVGCTPCIGEHWEKALPCAGQAQDNGACPPIELKNTVIQDGDMADIGFGNINFKT
LQQNRSDVSLDIVDEICKYPDFLKMQNDIYGDACFFYARREQCYARHFFVRGGKTGDD
IPAAQTDDGNMKNQYYIPAAQDQAQKDLGNAMYFPTVSGSLVSSDAQLFNRPFWLQRA
QGHNNGILWANQMFVTVVDNTRNTNFSISVYSEGGQIKDIRDYTSTQFREYLRHVEEY
EISVILQLCKIPLKAEVLAQINAMNPLLLEDWQLGFVPTPDNPIHDTYRFIDSLATRA
LTNPPKEKPDPYEGLNFWNVDLSERLSLDLDQYSLGRKFLFQAGLQQTTVNGTKTTMR
GSLRGTKRKRKN"
ORIGIN
1 aacggtaagt tgtattaaac tgtaccaggt gcggtgctat ttctcaatac agagctgtgg
61 ttgccaacta caattatctc tttcaagttt ttgcttgtat cgttttcgta taataacaac
121 ctctgtatat aattaaataa atatatatat ttgtttgaag atttggctga tttgcaattt
181 ggtgggcgaa tggagaggca gacaaatcaa gaagctacag ctaaccaaac tctgcagctt
241 cccacatcaa ttaaagagtt agcagatcta ttagagatac cattggtaga ttgtttaata
301 ccttgtaatt tctgtgggag gtttttagat tatttagagc tttgtgagtt tgacaaaaag
361 aagcttactt tgatttggaa agactacttt gttactgcat gctgtcgtag ttgctgtgta
421 gccacagcaa catttgaatt taatgaacat tatgagcaaa ctgttttagg aagggacata
481 gaattggcta caggtctttc aatatttgag atcaacatca ggtgtcaaac ttgcctatcc
541 tttcttgatc tgatagaaaa gctagatagt tgtggcggag gccttccctt tcataaggtc
601 agaggaggtt ggaagggaat ttgcagacat tgcaaacatt tgtataatga ttggtaaaga
661 ggtcaccgtg caagactttg ttttggagct tagtgagata cagcctgaag tattaccagt
721 tgacctgttt tgtgaagagg aattgccaaa cgagcaggag gaggagctag acatccagaa
781 gactgtattc aaaatcatag caccgtgtgg ctgcagttgc tgtgaggtca atcttcgtat
841 ttttgtgaac gctaccgacg ttggaattag aaccctgcaa gagctactga ccagtgacct
901 gcaactgctg tgtccagagt gccgtggtaa ctgcaaacat ggcggatcct aaaggtagta
961 catctaaaga agggttaagt gattggtgtt tgttggaagc tgactgtagt gatttagaaa
1021 atgattttga acaattgtgt gagagagata cagactcaga tatctcggac ttattagata
1081 attgtgacct ggaacagggc aattctttgg aactatttca tcaacaggag tgtaaggaga
1141 gcggggagca attacaaaaa ctaaaacgaa agtatcttag tccaaaagct gtcgcgcagc
1201 tcagtccgcg tctcgagtca atttcattgt cacctcagca gaaatccaag cgaaggctct
1261 ttgcagagca ggacagcgga ctcgagttat cacttaacaa tgaagctgaa gatgtttctc
1321 ctgaggtgga ggtaccggct atagactctc ggccggtaga gggaggatca ggggatgtag
1381 atattaatta cacagcgctt ttgcgatcca gcaaccacag agctacttta ttgtcaaaat
1441 ttaaagacgc gtttggggta ggctttaacg aattgacacg tcaatttaaa agttacaaaa
1501 cctgttgtaa tgattgggtc gtagctgttt atgcagttca tgatgatcta tttgaaagct
1561 caaagcagtt gttgcaacag cattgcgact atatctgggt tagtggaata ggcgcaatga
1621 cattatatct attatgtttt aaggcgggaa aaaatcgtgg tactgtacat aagctaacta
1681 cctcaatgtt aaatgtgcat gaacagcaaa tcttgtctga gccacctaag ttaagaaata
1741 ctgctgctgc attgttttgg tacaaagggt gtatggggtc agggacgttt acatatggcc
1801 cataccctga gtggattgct catcaaacta tacttggtca ccaaaatgct gaagcaagca
1861 cgtttgatct ttctgtaatg gttcaatggg catttgatca caatctggtg gatgaagcag
1921 atattgctta caaatatgca aagcttgcac cagaagatag taatgcagta gcttggcttg
1981 ctcataataa tcaggcaaaa tttgttcgtg aatgtgcatc aatggtgcga ttttataaaa
2041 aaggccaaat gaaagaaatg agtatgtcag aatggatata cactaagata aatgaggttg
2101 agggagaagg tcattggtca tctattgtta aatttttaag atatcaggga atcaatttca
2161 ttatgttttt ggctgcatta aaagattttt tgcatgcagt accaaagaaa aattgtattt
2221 taatatatgg acctcctaat tcagggaagt catcctttgc tatgtcctta atcaaggtgc
2281 tgaaaggtag agtcctgtcc tttgtaaatt ctaaaagcca gttttggttg caaccactct
2341 ctgaatgcaa aattgcacta ttggatgacg taacagatcc gtgctggcta tatatggaca
2401 aatatttaag aaatggccta gacggccatt ttgtgtctct agactgcaaa tataaagctc
2461 ctatgcaaac aaaattccct ccattgttac ttacttccaa tattaatgta catgcggaag
2521 taaattacag atatttacat agtagaatta aaggatttga gtttccaaat ccttttccaa
2581 tgaaatcaga taatacaccc gagtttgaat taactgacca aagctggaaa tctttttttg
2641 aaaggctttg gacacaatta gagctgagtg accaagaaga cgagggcgaa aatggagaat
2701 ctcagcgagc gtttcaatgt tctgcaagat cagctaatga acatatatga agctgcagaa
2761 cagacacttg aggcacaaat cacacactgg acattgttgc gaaaagaagc tgtgttgctt
2821 cattttgcta ggcaaaaggg tgttacaagg cttggatacc aacctgtgcc cccattagca
2881 gtaactgaag caaaagccaa agaggccata gggatgatgc tgcaactgca gtctctgcaa
2941 aagtctgagt atgcatcgga gacatggact ttagtggaca ctagcactga gacctttaga
3001 agtgctccag aaaatcattt taagaaaggc ccagtgtctg tggaggtgat ttatgataaa
3061 gacccagaga atgctaatgc atacactatg tggaattatg tttattatat ggattcagat
3121 gatgtttggc acaaaaccac aagtggggtg aatcaaactg gcatatatta catgcatggc
3181 aattttaagc actattatgt tgtatttgct gatgatgcaa gtagatatag tgctaccgga
3241 cagtgggaag taaaggttaa taaggaaact gtgtttgctc ctgtcaccag ctccacccct
3301 ccagggtcac caggacaaac agacacaaac gcctcctcca cgacccccac aaccacctct
3361 gactccgcgt ccagacacca acagccacaa caaaccgaag ccaaaggacg acaatacgga
3421 agacgaccat ccagcagaac acggcgacag gaaacgcagc aaaggagaag gcgatcaagg
3481 tcgcgatacc gttcccgttc tcgctcccgt tcccggtcgc gggccaagtc ccaagccggg
3541 ttacgggcca tacgcgccac ctccatatcc aggtccaggt ccccgtcggt cacccagact
3601 gggtcaggtt caggtctcgg tccagatctc gatccagaac cagactcgca gccacctcta
3661 ggcgaagggg aggtggaggg tcaccccggc ggcgctccaa atcacccgcc accccttccc
3721 gagaacggga agaaaacaga agggcgcggg gaggaaggag caacgggagg agcgggcgac
3781 gtaggggaag atcatcttcc accccccccc acccccaccc ccacaaaacg gcgaagaaca
3841 gagtctgtta gggtgcgcgg cgtctctcct gacgaagtgg gaaaatcact tcacacagtt
3901 agtgcaagaa atagaggaga acttggaaga ttattggagg aagctctcga tcccccagta
3961 attctatgtc gcggggaggc gaataccctg aaatgctttc gcaacagagc taaaaagaaa
4021 tatgagggct tgttcagggc atttagcact acgtggtcct gggtggctgg agatagcatt
4081 gagcgtctag gcaggcccag aatgctcatt agctttgctt cagacagaca aagaaaacat
4141 tttgatgtca ctgttaaata tccgaagggt gtagagacat cgtatggcaa cctggacagc
4201 ctgtaacagt actaatgcag ctttgctact aacttatact aacatttaac ccattacttt
4261 ttacattttt tacgtgtttt tatattgcta tggcgcgagc taaacgagtc aaacgcgact
4321 ctgtaacaca tatatatcaa acctgcaagc aagcaggtac ctgccccccc gatgttctta
4381 ataaagttga acaaacaaca gttgctgaca atattttaaa atatggcagt gctggtgttt
4441 tctttggagg ccttggcatt agcaccggcc gtggtaccgg gggcatcacg ggatataccc
4501 cacttggtga aggtcctggc gtctgtgttg gaaatactcc cacggtggta aggccttccc
4561 ttgttcctga aactgttggg cctatgaata tattaccaat tgatactctc aatcctgtgg
4621 aacctactgc atcctctgtg gtcccactca ctgaatcctc tgcatctgat ctccttccag
4681 gggagatcga aactattgct gagattcatc cagttcctga gggtccagtg gttgattctc
4741 ctgttgtcac cacaagcaag ggctccagtg ccattttaga ggttgcacca gaaccaagtc
4801 caccaacacg tgttagggtg tcacgtacac agtatcacaa tccatctttt cagagcatca
4861 cagagtctac acctgcacag ggtgaaagtt ctttagctga tcatgtgttg gtcacttctg
4921 gagccggtgg gcaatccata ggcagtgaga tcacagatat tatagaatta caggaatttc
4981 ccagtaggta ttcctttgaa attgaggaac ctactccacc acgacgtact agtactccat
5041 ctcaaaggcc acaagtatta gggcaacgta gagggctgtc attgaccaac agaaggctag
5101 ttcagcaagt accagtagac aactctttat ttttaactca gccatctaaa ttggttcgtt
5161 ttgcttttga taatcctgta tttgaagagg aggtcactaa tatttttgaa caggatattg
5221 atgagttcga ggagccgcct gacagagatt ttcttgatgt gcgtcagcta ggccgccctc
5281 aatattctac taccccagca ggatacgtgc gggtcagcag gctaggcaca cgtgggacca
5341 ttcgcacacg ctcgggagca caaatagggt ctcaagttca tttctatagg gacctgagtt
5401 ctattaatac agaagatcct attgaattac aattcctagg tcaacactct ggggatgcca
5461 caatagtgca aggtccagtg gaaagcacct ttatagatgt agatatgtca gaaaatcctt
5521 tgtcagagac tgttgacgct ggatccgaag atttcttatt agatgaggct gttgaggact
5581 tcagtggatc ccaattagtg ataggtaata gacggagtac aacatcctat actgtacccc
5641 gttttgaaac aacaaggaac agctcatatt atgtgcagga cacaaagggc tattatgtgg
5701 catatcctga gagtcgcgat actgcagaga tcatctatcc aactcctgat atacccatag
5761 ttgttataca tacccatgat agcagtggcg atttttattt acatcccagc cttcgcaaac
5821 ggaagcgtaa aagaaaatat ttatgatttt gcattcacag atggcagtgt ggcaatcggc
5881 acatggtaag gtatacttgc caccatcaac accagtggcc agggtgcaaa gcacggacga
5941 atacatacaa aggactaaca tctactatca tgcaaatact gacagacccc ttactgtagg
6001 tcatccatat tttaatgtat ataacaacac tggtgagaca ttacaggttc ctaaggtatc
6061 aggcaatcaa cacagggtgt ttcgtctgaa gttgcctgat ccaaacagat ttgcattagc
6121 tgacatgtca gtttataatc cagataagga gcgtttggtg tgggcctgta gaggtttgga
6181 aataagtaga gggcaaccct taggtgtcgg cagcacaggt cacccttact ttaataaact
6241 gaaggatact gaaaacagta atcaatattc caccacttcc aaagatgaca gacaaaatac
6301 ctcttttgac ccaaaacaaa tacagatgtt catagttgga tgtacacctt gtattgggga
6361 acattgggaa aaggctttgc catgtgcagg acaggcgcag gacaatggag cctgtcctcc
6421 tatagaatta aagaacactg ttatccagga tggggatatg gcagatattg gctttggtaa
6481 tataaacttt aaaacattac aacaaaatag gtcagatgtc agtttagata ttgtagatga
6541 aatttgcaaa tatccagatt ttctaaaaat gcaaaatgat atatatggag acgcatgctt
6601 cttttatgct cgaagagaac agtgttatgc tagacacttt tttgttagag gaggtaaaac
6661 aggtgacgat attcctgctg cacaaaccga tgatggcaat atgaaaaatc aatattacat
6721 tcctgcagca caggatcagg ctcaaaagga ccttgggaat gccatgtatt tcccaactgt
6781 tagtggctca ttagtttcaa gtgatgccca attgtttaac aggcccttct ggctacagcg
6841 agctcaaggt cataataatg gcatcttgtg ggccaaccaa atgtttgtca ctgtggtaga
6901 caacacacga aacaccaatt tcagtatttc agtttatagt gaaggtggac aaataaaaga
6961 tatcagggac tacacatcta cacagttcag ggaatattta aggcatgtgg aggaatatga
7021 aatatctgtc atattgcagt tatgtaaaat acctttaaaa gcagaagtct tggctcagat
7081 aaatgccatg aaccccttat tattggagga ctggcaatta ggatttgtcc ctacacctga
7141 caatccaatt catgatacct acagatttat tgactctttg gctacccgtg ccctgacaaa
7201 tcccccaaaa gaaaaacctg acccttatga aggcttaaac ttttggaatg tagatttatc
7261 agaacgtttg tcattagatt tggatcaata ctctttggga cgcaaatttt tgtttcaagc
7321 tgggttacaa caaacgaccg ttaacggtac aaaaactaca atgcggggtt ctttaagggg
7381 aaccaaacgc aaaagaaaaa attaacttaa gaccgatatc ggtacatctc cctcaacttt
7441 tacacagtat tcaaggaatg tttgtgttac tctgactaag cataacgctg cctaggaaat
7501 taaccgcgcc cggtacataa aaggtgagtt ggtgccaaat gagattcagt ttggtgccag
7561 gacagacctt gtaggttcta acatgctcgg attagggtat tcgccaagga agttttagct
7621 tgccaagttt cttttggcac tcttatttgg cacagtcgca gaccgat
//
