LOCUS X13744 4213 bp DNA linear VRL 18-APR-2005
DEFINITION Avian Retrovirus IC10 proviral genome.
ACCESSION X13744
VERSION X13744.1
KEYWORDS mil oncogene; provirus; Rmil oncogene; serine threonine kinase.
SOURCE Avian retrovirus IC10
ORGANISM Avian retrovirus IC10
Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes;
Ortervirales; Retroviridae; Orthoretrovirinae; Alpharetrovirus.
REFERENCE 1 (bases 1 to 4213)
AUTHORS Eychene,A., Marx,M., Dezelee,P. and Calothy,G.
TITLE Complete nucleotide sequence of IC10, a retrovirus containing the
Rmil oncogene transduced in chicken neuroretina cells infected with
avian retrovirus RAV-1
JOURNAL Nucleic Acids Res. 17 (3), 1250 (1989)
PUBMED 2537952
REFERENCE 2 (bases 1 to 4213)
AUTHORS Dezelee,P.
TITLE Direct Submission
JOURNAL Submitted (15-DEC-1988) Barnier J.V., Institut Curie, Centre
Universitaire, Bat 110, 91405 Orsay Cedex, France
FEATURES Location/Qualifiers
source 1..4213
/organism="Avian retrovirus IC10"
/proviral
/mol_type="genomic DNA"
/isolate="IC10"
/db_xref="taxon:11874"
/cell_line="neuroretina cells from chicken embryos"
/clone_lib="lambda gt11"
repeat_region 1..54
/note="U3 region of 5'LTR"
/rpt_type=long_terminal_repeat
repeat_region 55..155
/note="R and U5 region of 5'LTR"
/rpt_type=long_terminal_repeat
CDS 453..3692
/note="unnamed protein product; gag-Rmil-env polypeptide
(1079 AA)"
/codon_start=1
/protein_id="CAA32008.1"
/db_xref="GOA:P10533"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR001245"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="UniProtKB/Swiss-Prot:P10533"
/translation="MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLTSPSD
LYSPGSWDPITAALSQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGG
GRVSPPGPESIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTFCYHCGTA
IGCNCATASAPPPPYVGSGLYPSLAGVGEQQGQGGDTPPGAEQPRAEQQHAGQAPGPA
LTDWARVREELASTGPPVVAMPVVIKTEGPAWTPLEPKLITRLADTVRTKGLRSPITM
AEVEALMSSPLLPHDVTNLMRVILGPAPYALWMDAWGVQLQTVIAAATRDPRHPANGQ
GRGERTNLDRLKGLADGMVGNPQGQAVLLRPGELVAITASALQAFREVARLAEPAGPW
ADITQGPSESFVDFANRLIKAVEGSDLPPSARAPVIIDCFRQKSQPDIQQLIRAAPST
LTTPGEIIKYVLDRQKTAPLTDQGIAAAMSSAIQPLVMAVVNRERDGQTGSGGRARGL
CYTCGSPGHYQAQCPKKRKSGNSRERCQLCDGMGHNAKQCRKRDGNQGQRPGRGLSSG
PWPGPDQPAVSLAMTMEHKDRPLVRVILTNTGSHPVKQRSVYITALLDSGADITIISE
EDWPTDWPVMEAANPQIHGIGEGGSTAGLSATPPASLPGSLTNVKALQKSPGPQRERK
SSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKML
NVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHI
IETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVK
SRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNI
NNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELL
ARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGIGEWAVHLLKGLLLGL
VVILLLVVCLPCLLQCVSSSIRKMIDNSLGYREEYKKLQEAYKQPERRA"
mat_peptide 453..2387
/product="deleted gag protein"
mat_peptide 2388..3488
/product="v-Rmil protein"
mat_peptide 3489..3689
/product="deleted env protein"
repeat_region 4006..4213
/note="U3 region of 3'LTR"
/rpt_type=long_terminal_repeat
ORIGIN
1 gaattccgca ttgcagagat attgtattta agtgcctagc tcgatacaat aaatgccatt
61 tgaccattca ccacattggt gtgcacctgg gttgatggcc ggaccgttga ttccctgacg
121 actacgagca catgcatgaa gcagaaggct tcatttggtg accccgacgt gatcgttagg
181 gaatagtggt cggccacaga cggcgtggcg atcctgtcct catccgtctc gcttattcgg
241 ggagcggacg atgaccctag tagagggggc tgcggcttag gagggcagaa gctgagtggc
301 gtcggaggga gctctactgc agggagccaa cataccctac cgagaactca gagagtcgtt
361 ggaagacggg aaggaagccc gacgactgag cggtccaccc caggcgtgat tccggttgct
421 ctgcgtgatt ccggtcgccc ggtggatcaa gcatggaagc cgtcataaag gtgatttcgt
481 ccgcgtgtaa gacctattgc gggaaaacct ctccttctaa gaaggaaata ggggctatgt
541 tgtccctgtt acaaaaggaa gggttgctta cgtccccctc agacttatat tccccggggt
601 cctgggatcc cattaccgcg gcgctctctc agcgggctat ggtacttgga aaatcgggag
661 agttaaaaac ctggggattg gttttggggg cattgaaggc ggctcgagag gaacaggtta
721 catctgagca agcaaagttt tggttgggat tagggggagg gagggtctct cccccaggtc
781 cggagagcat cgagaaacca gcaacggagc ggcgaattga caagggggag gaagtgggag
841 aaacaactgt gcagcgagat gcgaagatgg cgccggagga aacggccaca cctaaaaccg
901 ttggcacatt ctgctatcat tgcggaacag ctattggctg taattgcgcc acagcctcgg
961 ctcctcctcc tccttatgtg gggagtggtt tgtatccttc cctggcgggg gtgggagagc
1021 agcagggcca ggggggtgac acacctccgg gggcggaaca gccaagggcg gagcaacagc
1081 atgcgggtca ggctcctggg ccagccctga ctgactgggc aagggtcagg gaggagcttg
1141 cgagtacagg tccgcccgtg gtggccatgc ctgtagtgat taagacagag ggacccgcct
1201 ggacccctct ggagccaaaa ttgatcacaa gactggctga tacggttagg accaagggct
1261 tacgatcccc gatcactatg gcagaagtgg aagcgcttat gtcctccccg ctgctgccgc
1321 atgatgttac gaatctaatg agagttattt tgggacctgc cccatatgcc ttgtggatgg
1381 acgcttgggg cgtccaacta cagacggtta tagcggcagc cactcgcgac ccccgacacc
1441 cagcgaatgg tcaagggcgg ggggaacgga ctaacttgga tcgcttaaag ggtttagctg
1501 atgggatggt gggcaaccca cagggtcagg ccgtattatt aagaccgggg gaattggttg
1561 ctattacggc gtcggctctc caggcgttta gagaagttgc ccggctggcg gaacccgcag
1621 gtccatgggc ggatatcacg cagggaccat ccgagtcctt tgttgatttt gccaatcggc
1681 ttataaaggc ggttgagggg tcagatctcc cgccttccgc acgggctccg gtgatcattg
1741 actgctttag gcagaagtca cagccagata ttcagcagct tatacgggca gcaccctcca
1801 cgctgaccac cccaggagag ataatcaaat atgtgctaga caggcagaag actgcccctc
1861 ttacggatca aggcatagcc gcggccatgt cgtctgctat ccagccctta gttatggcag
1921 tagtcaatag agagagggac ggacaaactg ggtcgggtgg tcgtgcccga gggctctgct
1981 acacttgcgg atccccggga cattatcagg cgcagtgccc gaaaaaacga aagtcaggaa
2041 acagccgtga gcgatgtcag ttgtgtgacg ggatgggaca caacgctaaa cagtgtagga
2101 agcgggatgg caaccagggc caacgcccag gaagaggtct ctcttcgggg ccgtggcccg
2161 gccctgacca gcctgccgtc tcgttagcga tgacaatgga acataaagac cgccccttgg
2221 ttagggtcat tctgactaac actgggagtc atccggtcaa acagcgttcg gtgtatatca
2281 ccgcgctgtt ggactctgga gcggacatca ctattatttc agaggaggac tggcccaccg
2341 attggccagt gatggaggcc gcgaacccgc agatccatgg gataggagag ggaggttcaa
2401 ctgcaggttt gtctgcaaca cctcctgcat ctttgcctgg gtcacttacc aatgtgaaag
2461 cattacagaa atcaccaggc ccccaacggg aaaggaaatc atcctcatcc tcagaagaca
2521 gaaataggat gaaaaccctt ggtcgacgag attcaagtga tgattgggaa ataccagatg
2581 ggcagatcac agttggacaa aggataggat ctggatcatt tggaacagtc tacaaaggaa
2641 agtggcatgg tgacgtggca gtgaaaatgt tgaatgttac agcacccaca cctcaacagt
2701 tacaggcttt caaaaatgaa gtaggagtgc tcaggaaaac acggcatgtg aatatcctac
2761 tttttatggg ttattcaaca aaacctcagt tggctattgt tacacagtgg tgtgaggggt
2821 ccagcttata tcaccatctg cacataattg agaccaagtt tgaaatgatc aaactaattg
2881 atattgcacg acagactgca caaggcatgg attatttgca tgccaagtca atcatccaca
2941 gagacctcaa gagtaataat atttttcttc atgaagacct cacagtaaaa ataggtgact
3001 tcggtctggc tacagtgaaa tcacgatgga gtggatctca tcaatttgaa cagttatctg
3061 gatcaattct atggatggca ccggaagtga tcaggatgca agacaaaaac ccatatagct
3121 ttcagtcaga tgtgtatgca ttcgggattg tgctttatga actgatgact ggacagttac
3181 catactcaaa catcaacaac agggaccaga taatttttat ggtgggacga ggatatctat
3241 ctccagacct cagtaaagta agaagtaact gtcccaaagc tatgaagaga ctaatggcag
3301 aatgcttgaa aaagaaaaga gatgagagac ctctttttcc acagattctt gcctccattg
3361 agcttctggc ccggtcgttg ccaaaaattc accgcagtgc atctgagccg tcactaaacc
3421 gggctggctt ccagaccgag gatttcagtc tgtatgcttg tgcttctcca aaaacgccca
3481 tccaagcagg aggaatagga gaatgggccg tacacttgct gaaaggactg cttttggggc
3541 ttgtagttat cttgttgcta gtggtatgct tgccttgcct tttgcaatgt gtatctagta
3601 gtattcgaaa gatgattgat aattcactcg gctatcgcga ggaatataaa aaattacagg
3661 aggcttataa gcagcccgaa agaagagcgt aggcgagttc ttatattccg tgtgatagct
3721 ggttggattg gtaattgatc ggctggcacg cggaatatag gaggtcgctg aatagtaaac
3781 ttgtagactt ggctacagca tagagtatct tctgtagctc tgatgactgc taggaaataa
3841 tgctacggat aatgtgggga gggcaaggct tgcgaatcgg gttgtaacgg gcaaggcttg
3901 actgagggga caatagcatg tttaggcgaa aagcggggct tcggttgtac gcggttagga
3961 gtcccctcag gatatagtag tttcgctttt gcatagggag ggggaaatgt agtcttatgc
4021 aatactcttg tagtcttgca acatgcttat gtaacgatga gttagcaaca cgccttataa
4081 ggagagaaaa agcaccgtgc atgccgattg gtggaagtaa ggtggtatga tcgtggtatg
4141 atcgtggtat gatcgtgcct tattaggaag gcaacagacg ggtctaacac ggattggacg
4201 aaccactgaa ttc
//
