KEGG   Geospiza fortis (medium ground-finch): 102035643
Entry
102035643         CDS       T03755                                 
Symbol
GCLC
Name
(RefSeq) glutamate-cysteine ligase catalytic subunit
  KO
K11204  glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2]
Organism
gfr  Geospiza fortis (medium ground-finch)
Pathway
gfr00270  Cysteine and methionine metabolism
gfr00480  Glutathione metabolism
gfr01100  Metabolic pathways
gfr01240  Biosynthesis of cofactors
gfr04216  Ferroptosis
Brite
KEGG Orthology (KO) [BR:gfr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    102035643 (GCLC)
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    102035643 (GCLC)
 09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    102035643 (GCLC)
Enzymes [BR:gfr01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.2  glutamate---cysteine ligase
     102035643 (GCLC)
SSDB
Motif
Pfam: GCS GCS2 SANT_DAMP1_like
Other DBs
NCBI-GeneID: 102035643
NCBI-ProteinID: XP_005427963
UniProt: A0A6I9HQ05
Position
Un
AA seq 583 aa
MLVKFDHENKKVRLLLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPDYMPTPVEGGASKSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAK
PDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSD
IDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDK
DIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFK
PPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKV
AQKRDAVRQGMFYFRKDICKGGNAVLDGCGSAQNGTGTDAEEYTLMSIDTIINGKEGVFP
GLIPILNSYLENMEVDVDTRCSILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSV
ITDEMNYSLMWRCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq 1752 nt   +upstreamnt  +downstreamnt
atgttggtaaaatttgaccatgaaaataagaaagtgcgtttgttactctgtggtgaagaa
gttcttcaaacactgcaagacaagggggagaaggtgaaccccaatcacccaacactctgg
agaccagaatatggaagttacatgattgaaggaacacctggacagccatatgggggaacc
atgtctgaattcaacactgtgcaagacaacatgaggaaaagacggcaagaggctgcttct
gtactcaaagaaaatgaggctgtttgcacagtgacatcatttccaaggttaggctgtcct
gggtttacactgccggattatatgccaacaccagtagaaggaggagcttcaaaatcgctc
ttttttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaacatt
cgacaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataagaacacg
ccatcacctttcattgaaacatttcctaatgatgatggagaagcagcaaaggcagctaag
ccagactacatatatatggatgctatgggttttggaatgggaaactgctgcctccaggta
acatttcaggcttgcagcatttctgaagcaaggtatctctatgatcagctagctacaatt
tgtcccattgtgatggcgctgagtgctgcgtctccattctacagaggctacgtgtctgac
attgactgtcgctggggagtgatctctgcctccgtggatgaccgaacgcgcgaggagcgg
gggctggagccactgaagaacaaccattatagaatcagtaaatccagatatgattccata
gacagttatctgtctgaatgtggtgagaaatacaatgacattgatttgacaatagacaaa
gatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcatattgca
cacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagatgatgca
aatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgaggtttaag
ccaccacctccaaattcagatattggatggagagtggaattcagacctatggaggtccag
ttaacagactttgaaaactcggcttatgttgtgtttgtggtattgctaaccagagtgatt
ctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatgaaggtg
gcccagaaaagagatgctgtacgacagggaatgttttacttcagaaaagatatatgcaaa
ggtggaaatgctgttttggatggatgtggctctgcacagaatgggacaggcaccgacgca
gaagagtacaccttaatgagcattgacacaattatcaatgggaaggaaggagtctttcca
gggttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggatacaaga
tgcagcatcctaaactacctgaagctaataaaaaagagagcctctggagagttaatgaca
gtggctcgatggatgagggaattcatcgcgcagcatccggactacaagcaagacagtgtg
ataactgatgagatgaattacagccttatgtggagatgcaaccagattgctcaaggccag
gcagagtgtcctgaactactgggggtaggatttaataagaaacagagtggaaataaaact
gactctttgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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