KEGG   Gallus gallus (chicken): 421348
Entry
421348            CDS       T01006                                 
Symbol
EPRS
Name
(RefSeq) bifunctional glutamate/proline--tRNA ligase
  KO
K14163  bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15]
Organism
gga  Gallus gallus (chicken)
Pathway
gga00860  Porphyrin metabolism
gga00970  Aminoacyl-tRNA biosynthesis
gga01100  Metabolic pathways
gga01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:gga00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    421348 (EPRS)
 09120 Genetic Information Processing
  09122 Translation
   00970 Aminoacyl-tRNA biosynthesis
    421348 (EPRS)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:gga01007]
    421348 (EPRS)
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:gga03016]
    421348 (EPRS)
Enzymes [BR:gga01000]
 6. Ligases
  6.1  Forming carbon-oxygen bonds
   6.1.1  Ligases forming aminoacyl-tRNA and related compounds
    6.1.1.15  proline---tRNA ligase
     421348 (EPRS)
    6.1.1.17  glutamate---tRNA ligase
     421348 (EPRS)
Amino acid related enzymes [BR:gga01007]
 Aminoacyl-tRNA synthetase
  Class I (A)
   421348 (EPRS)
Transfer RNA biogenesis [BR:gga03016]
 Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    421348 (EPRS)
SSDB
Motif
Pfam: tRNA-synt_1c WHEP-TRS ProRS-C_1 HGTP_anticodon tRNA-synt_2b tRNA-synt_1c_C tRNA-synt_1c_C2 Arc1p_N_like GST_C GST_C_2 tRNA-synt_1e DUF5535 GST_C_3
Other DBs
NCBI-GeneID: 421348
NCBI-ProteinID: NP_001006398
CGNC: 7307
Ensembl: ENSGALG00000009598
UniProt: Q5ZJ86
Structure
Position
3:18517316..18554404
AA seq 1601 aa
MAALSLTVQADSPPLGALLTVELVKNDVKISVEEGKETILRVSEHVSFTNVNSIVRYLAR
VAASAGLYGANLLEHTEIDHWLEFSATKLSTASQFLSAVQELNHCLSLRTYLVGNSLSLA
DVCVWAVLKDNNIWQEQLQQNKAPIHAKRWYGFLDVQQAFQSVGAKWASGTPKVKMATEK
KADVGKFVELPGAEMGKVIVRFPPEASGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTN
PEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETIMKYAEQLIQEGKAYVDDTPAEQMK
AEREQRTESKHRNNCVNKNLQMWEEMKKGTEYGQTCCLRAKIDMNSNNGCMRDPTLYRCK
NQPHPRTGTTYKVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIRKPYI
WEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGS
SRSVVNMEWDKIWSFNKKVIDPVAPRYTALLKDAVVPVNVPEAQEEMKEVAKHPKNADVG
LKPVWYGSKVLIEGADAETLTEGEVVTFINWGNIIITKLNRNSSGKIVSIDTKLNLDNKD
FKKTTKITWLAETPRAPLIPTVCVNYEHLITKPVLGKDEDFKQYINRNSKQEELMLGDPC
LKDLKKGDIIQLQRRGFFICDQPYEPVSPYSCKEAPCILIYIPDGHTKEMPTSGSKEKTK
AETAKKEASSAVKGKSVPLADDTSTATCTASEDHLVMYNRVAAQGDIVRDLKAKKAAKED
IDKAVKQLLALKAEYKEKTGQEYKPGNPPAAVTKQHASSTHENSATLDCKALYDKVAEQG
EVVRKLKAEKAPKEQVDEAVKVLLNLKAEYKQKTGQEYKPGNPPSAPPCASSATLPSSVC
CNNLGPSSLVDAKALYDNVAEQGEVVRRLKAEKASKGEIDEAVKLLLSLKADYKEKTGQD
YKPGHPPVAQDSLPQASNTIPSGPDTTEAKALFNKVALQGDEVRKLKAEKAEKEKIDAAV
KELLQLKAQYKSVAGVDYKPASASSADDKDKKKKEKENKSEKQCKQQKQNDGPKKEPLQG
QSGNELSSNGPGEGQGPKKQTRLGLEAKKEENLADWFSQVITKAEMIEYYDVSGCYVLRP
WAYAIWEAIKNFFDAEIKKLGVENCYFPMFVSQAALEKEKSHIADFAPEVAWVTRSGKTE
LAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQE
GHSAFATYEEAAEEVMQILDLYAQVYEDLLAIPVVKGRKTEKEKFAGGDYTTTVEAFISA
SGRAIQGATSHHLGQNFSKMFEVMFEDPKKPGEKQYAYQNSWGITTRTIGVMTMIHGDNV
GLVLPPRVACVQVVIIPCGITNTLSEEDKEALLKKCNEYRKRLLSANVRVRADLRDNYSP
GWKFNHWELKGVPIRLEVGPRDMKSQQFVAVRRDTGQKLTFSEHEAEDKLKQVLEEIHAN
LYNRASEDLRSHMVVANTMEDFQKELDSGKIVQIPFCGESECEDWIKKTTARDQDLEPGA
PSMGAKSLCIPFQPLRELQSGAKCVCGKNPAKFYTLFGRSY
NT seq 4806 nt   +upstreamnt  +downstreamnt
atggcggcgctgagcctcacggtgcaggcggacagccccccgctcggagctctgctgaca
gtggagcttgtgaagaatgatgtcaaaatttcagtggaagaaggcaaggaaaccatcctt
cgtgtatctgagcatgtttcatttaccaatgtgaattcaatagttcgctacctggctaga
gttgctgcttctgctgggttgtatggtgcaaaccttttggaacacactgagatcgaccac
tggctagagtttagtgctacaaagttatctactgccagccagtttctttcagcagtccaa
gagctcaaccactgcctatctctgagaacctacttggttggaaactctctgagtcttgca
gatgtctgtgtctgggctgtcctaaaagataataacatctggcaagagcaattacagcaa
aataaagctcccatccatgcaaaacgatggtatggctttcttgatgtccaacaagctttt
cagtctgtaggagccaagtgggcttctggcactccaaaggtcaaaatggcaactgaaaag
aaagcggatgttgggaagtttgttgagcttcccggtgcagagatgggaaaggtcattgta
cgatttcctcctgaagcaagtggatatctgcatatcggtcatgccaaagctgctctgcta
aatcaacactaccaggttaacttcaaaggcaaacttattatgaggtttgatgacacaaat
cctgaaaaagagaaagaagactttgaaaaggttattcttgaagatgtcgcaatgctgcac
atcaaaccagaccaatttacatatacctcagatcactttgaaacaataatgaaatacgct
gagcagcttattcaagaagggaaggcatatgtggatgatactcctgcagaacagatgaaa
gcagagcgtgagcaaagaacggaatctaaacacagaaataactgtgttaacaagaatcta
caaatgtgggaagaaatgaaaaagggaacagagtatggacaaacttgttgtctacgagca
aaaatagatatgaatagtaacaatggatgtatgagggatccgactctttatcgttgtaaa
aaccagcctcacccacgtacaggaactacctacaaggtttatcctacatatgactttgcc
tgccccatcgttgacagtattgaaggtgtcacacatgctcttagaacaacggaataccat
gacagggatgaacagttctactggatcattgaggcattgggcataaggaagccgtacata
tgggaatacagcaggctaaacctcaacaacactgtgctgtccaaaagaaagcttacgtgg
tttgtcaatgaagggcttgtggatggatgggatgacccaaggtttcccactgtgcgtggt
gtcctgagaagaggcatgacggttgaagggctaaaacagttcattgctgctcagggctcc
tctcgatctgttgtgaatatggagtgggataaaatttggtccttcaacaaaaaggttata
gatccagtagcacctcggtacactgctttactgaaagatgcagtggtcccagtcaatgtt
cctgaagctcaagaggagatgaaggaagtggctaaacatccaaagaatgccgatgttggg
ttgaaacctgtgtggtatggctccaaagtgctgatagagggtgcagatgcagagaccctg
acagagggagaggtggttacgttcataaattggggcaatattatcatcactaaattaaac
agaaattcaagtggaaaaattgtgtccattgataccaagttgaacttagataataaagac
ttcaaaaaaaccactaagatcacttggttagcagagactccacgtgcaccactcatccca
accgtttgtgttaattatgaacatctgatcactaaaccagttctaggtaaagatgaagat
ttcaagcaatatatcaaccgaaatagcaagcaagaagaactgatgttaggtgatccttgt
cttaaggatttaaagaaaggggacattatccaacttcagaggagaggattctttatttgt
gatcaaccctatgagccagtgagtccatatagctgtaaagaggccccatgcattttgatt
tacatccctgatggacacactaaggaaatgccaacatctgggtcaaaagagaagaccaaa
gctgaaactgcaaagaaagaggctagttcagctgtaaaaggaaaatctgttccacttgct
gatgatacctctactgcaacctgtactgcctcagaagaccacctggttatgtacaacagg
gtggctgcacagggtgatattgttcgtgatttgaaagctaagaaggcagcaaaggaagat
attgataaagctgtgaagcagttgctggccttgaaagcagaatacaaagagaagacgggc
caggagtataagcctggaaatcctccagcagctgtaactaaacagcatgcgtcttcaaca
catgagaactctgctaccctggactgcaaagctctgtatgataaagtagcagagcaagga
gaagtggtccgaaaactgaaagctgagaaagcacctaaggaacaagtagatgaagctgtg
aaggttctcttaaatctgaaagcagaatataaacaaaagacaggtcaagagtataagcct
ggaaatccaccttcagctcctccttgtgcgtcttctgctacacttccatcttctgtatgc
tgcaataacttgggaccttctagcttagtggatgccaaagcactttatgataatgtagct
gaacaaggggaagtggtgcgacgactcaaggcagagaaagcttccaagggtgaaatagat
gaagcagtaaaactcctcctttctctaaaagctgactataaggaaaagactggacaggac
tacaagcccggacatccgccagtagctcaggattctttgccccaggcatcaaatacaata
ccaagtggtcctgacacaactgaagctaaagcactgtttaacaaagtagctcttcaagga
gatgaagttaggaaattgaaagcagaaaaagcagaaaaggaaaagatagatgcagctgtt
aaagagcttcttcagctaaaggctcaatacaagtctgttgcaggagttgattataaacct
gcttctgctagtagtgctgatgacaaagacaaaaagaagaaagagaaagagaacaagtca
gaaaagcagtgtaagcaacagaaacaaaatgatggaccaaaaaaagagcctttgcaagga
cagagtggtaatgagctctcttcaaatgggccaggagagggtcaaggccctaagaaacaa
accaggttgggtttggaagccaaaaaagaagaaaatcttgcagactggttctctcaggtg
atcacaaaagcagagatgattgaatactatgatgtgagtggctgttatgttcttcgtcct
tgggcttatgccatttgggaagctatcaagaacttctttgatgctgagatcaagaaactt
ggtgtggaaaactgctacttccccatgttcgtgtcccaagctgcactagagaaagagaag
agtcatattgctgattttgcccctgaggttgcttgggtcacaagatctgggaaaacagaa
ctcgctgaaccaattgctatacgtcccacaagtgaaacagttatgtatcctgcatatgca
aagtgggtgcagtcccacagagatcttcctatcaagcttaatcagtggtgcaatgttgtg
cgttgggagttcaaacatcctcagcctttccttcgcactcgtgagttcctttggcaggag
ggtcactcggcatttgcaacatatgaagaagctgcagaggaagtcatgcagatacttgat
ctttacgctcaagtgtacgaagatctcctagcaatacctgttgtgaaaggaagaaagaca
gaaaaggagaaatttgctgggggtgactatacaacaactgtagaggcatttatatctgcc
agtggaagagctatccagggtgcaacatcacatcacctagggcagaatttctcaaagatg
tttgaagtcatgtttgaagatcccaagaaaccaggagaaaaacagtatgcgtatcagaat
tcctggggcattacaactcgaactattggtgtaatgacaatgattcatggagataatgtg
gggttggtgctcccgcctcgagtagcttgtgttcaggttgtaattattccctgtggtatc
acaaataccctttctgaagaggacaaagaggctttattgaagaaatgtaatgagtatcgt
aaaaggctgcttagtgctaatgtccgtgtacgtgctgatttaagagacaactattcacct
ggctggaagttcaatcattgggaacttaagggtgtacctatcaggcttgaagtgggaccg
cgagacatgaagagccaacagtttgtagctgtcagaagagacacgggacagaagctgacc
ttttcagaacatgaggcagaagataaactgaagcaggttttggaggaaatccatgctaat
ctatacaacagagcttctgaagacttaagaagtcatatggtggtggccaatactatggaa
gactttcaaaaagagcttgattcaggaaagattgtacaaatccctttttgtggggaaagt
gagtgcgaggattggatcaagaagaccactgccagagatcaagatctggagcctggtgcc
ccctccatgggagcaaaaagtctttgcatacctttccagcctctccgtgaactacagagt
ggggcaaaatgtgtctgcggcaagaaccctgccaagttctacaccctctttggtcgtagt
tactaa

  All links  
Gene (59)   
   RefGene (54)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   CGNC (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (1)   
   RefSeq(pep) (10)   
DNA sequence (18)   
   RefSeq(nuc) (10)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (13)   
   Pfam (13)   
All databases (102)   

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