KEGG   Gallus gallus (chicken): 423778Help
Entry
423778            CDS       T01006                                 

Gene name
MAPK8
Definition
(RefSeq) mitogen-activated protein kinase 8 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
gga  Gallus gallus (chicken)
Pathway
gga04010  MAPK signaling pathway
gga04012  ErbB signaling pathway
gga04068  FoxO signaling pathway
gga04137  Mitophagy - animal
gga04140  Autophagy - animal
gga04141  Protein processing in endoplasmic reticulum
gga04210  Apoptosis
gga04217  Necroptosis
gga04310  Wnt signaling pathway
gga04510  Focal adhesion
gga04530  Tight junction
gga04620  Toll-like receptor signaling pathway
gga04621  NOD-like receptor signaling pathway
gga04622  RIG-I-like receptor signaling pathway
gga04625  C-type lectin receptor signaling pathway
gga04910  Insulin signaling pathway
gga04912  GnRH signaling pathway
gga04914  Progesterone-mediated oocyte maturation
gga04920  Adipocytokine signaling pathway
gga04933  AGE-RAGE signaling pathway in diabetic complications
gga05132  Salmonella infection
gga05164  Influenza A
gga05168  Herpes simplex infection
Module
gga_M00688  MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:gga00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    423778 (MAPK8)
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    423778 (MAPK8)
   04012 ErbB signaling pathway
    423778 (MAPK8)
   04310 Wnt signaling pathway
    423778 (MAPK8)
   04068 FoxO signaling pathway
    423778 (MAPK8)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    423778 (MAPK8)
   04137 Mitophagy - animal
    423778 (MAPK8)
  Cell growth and death
   04210 Apoptosis
    423778 (MAPK8)
   04217 Necroptosis
    423778 (MAPK8)
  Cellular community - eukaryotes
   04510 Focal adhesion
    423778 (MAPK8)
   04530 Tight junction
    423778 (MAPK8)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    423778 (MAPK8)
   04621 NOD-like receptor signaling pathway
    423778 (MAPK8)
   04622 RIG-I-like receptor signaling pathway
    423778 (MAPK8)
   04625 C-type lectin receptor signaling pathway
    423778 (MAPK8)
  Endocrine system
   04910 Insulin signaling pathway
    423778 (MAPK8)
   04920 Adipocytokine signaling pathway
    423778 (MAPK8)
   04912 GnRH signaling pathway
    423778 (MAPK8)
   04914 Progesterone-mediated oocyte maturation
    423778 (MAPK8)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    423778 (MAPK8)
  Infectious diseases
   05132 Salmonella infection
    423778 (MAPK8)
   05164 Influenza A
    423778 (MAPK8)
   05168 Herpes simplex infection
    423778 (MAPK8)
Enzymes [BR:gga01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     423778 (MAPK8)
Protein kinases [BR:gga01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   423778 (MAPK8)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo Kinase-like RIO1 APH DUF530 FTA2
Motif
Other DBs
NCBI-GeneID: 423778
NCBI-ProteinID: XP_001233169
CGNC: 4584
Ensembl: ENSGALG00000006109
Position
6
AA seq 427 aa AA seqDB search
MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQ
MELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSF
MMTPYVVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMIKGGVLFPGTDHIDQWNKVIEQ
LGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEV
MDLEERTKNGVIRGQPAPLGAAMINGSQHPSSSSSVNDVSSMSTDPTLASDTDSSLETSA
GPLGCCR
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgagcagaagcaagcgtgacaacaatttctacagtgttgaaattggagattctacattc
actgtattgaaacggtatcaaaacttaaaaccaataggatcgggagcgcaaggaatagta
tgtgcagcctatgatgccatccttgagcgaaacgttgcaatcaagaaactaagccgacca
tttcagaatcaaacccatgctaaaagagcctacagagagcttgttcttatgaagtgcgtt
aatcacaaaaatataatcggcttactgaatgtgttcacaccacagaaatccctggaagaa
tttcaagatgtctacatagtaatggagctcatggatgcaaatctctgccaagtgattcag
atggagctagaccatgaacgaatgtcctatctcctttatcagatgctgtgtggtatcaaa
catcttcactcagctggaattatacatagggacttaaagcccagtaatatagtagtaaag
tcagactgcactttgaagattcttgactttggactggccagaactgcaggaactagtttt
atgatgacgccttatgtagtgactcgttactacagagcaccagaggtcatcctagggatg
ggatacaaagaaaacgttgacatttggtcagttgggtgcatcatgggagaaatgatcaaa
ggtggtgttttatttcctggtacagatcatattgatcaatggaataaagttatagagcag
ctaggaacaccgtgcccagaatttatgaagaaattacagcccacagttcgaacttatgtg
gagaacagacccaagtatgctggatacagctttgagaaactctttccagatgtccttttc
ccagctgattctgaacacaacaaacttaaagcaagtcaagcaagggatttgttatcaaaa
atgctggttatagacgcctcgaaaagaatttctgtggatgaagccctccagcacccatac
atcaatgtttggtatgatccatcagaagccgaagctcctccaccaaagataccagataag
cagttagatgagagggagcacacaatagaagaatggaaagaattgatatacaaagaagtc
atggacctggaggaaagaaccaagaatggggttatacgtgggcagccagcccctttaggt
gcagcaatgatcaatggctctcagcatccatcttcgtcgtcatctgtcaacgatgtgtct
tcaatgtcaacggatccaacattggcctctgatacagacagcagtctagaaacctcagct
ggacctctgggttgctgtagatga

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