KEGG   Gallus gallus (chicken): 429083
Entry
429083            CDS       T01006                                 
Symbol
DPYD
Name
(RefSeq) dihydropyrimidine dehydrogenase [NADP(+)] isoform X2
  KO
K00207  dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2]
Organism
gga  Gallus gallus (chicken)
Pathway
gga00240  Pyrimidine metabolism
gga00410  beta-Alanine metabolism
gga00770  Pantothenate and CoA biosynthesis
gga00983  Drug metabolism - other enzymes
gga01100  Metabolic pathways
Module
gga_M00046  Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate
Brite
KEGG Orthology (KO) [BR:gga00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    429083 (DPYD)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    429083 (DPYD)
  09108 Metabolism of cofactors and vitamins
   00770 Pantothenate and CoA biosynthesis
    429083 (DPYD)
  09111 Xenobiotics biodegradation and metabolism
   00983 Drug metabolism - other enzymes
    429083 (DPYD)
Enzymes [BR:gga01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.2  dihydropyrimidine dehydrogenase (NADP+)
     429083 (DPYD)
SSDB
Motif
Pfam: DHO_dh Fer4_20 Fer4_21 Pyr_redox_2 NAD_binding_8 Dus Pyr_redox_3 Fer4_10 Fer4_7 Pyr_redox Fer4_6 Fer4_2 Fer4_9 Fer4 MurD-like_N Thi4 DAO FAD_binding_2 MCRA
Other DBs
NCBI-GeneID: 429083
NCBI-ProteinID: XP_025008718
CGNC: 4104
Ensembl: ENSGALG00000005509
Position
8:12974460..13291393
AA seq 962 aa
MRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDNPLGLTCGMVCPTSDLC
VGGCNLYATEEGPINIGGLQQFATEVFKAMNIPQIRNPSLPSPEDMPEAYHVKIALLGAG
PASLSCASFLARLGYSNITIFEKQEYVGGLSASEIPQFRLPYDVVNFEAELMKDLGVKII
YSKGLAVDGMTLRTLKEDGYEAVFIGIGLPEPNRDSVFQGLRMDQGFYTSKDFLPLVAVA
SKPGMCACQSPLPSIHGTVIVLGAGDTAFDCATSALRCGARRVFVVFRKGFTNIRAVPEE
MELAKEERCEFLPFLSPRKVVLRSGHIVAMEFVRTEQGSDGNWKEDEDQVVRLKADVVIS
AFGSVLSDSKVIEAMTPIKFNRWGLPEVDPETMQTSEPWVFAGGDISGHANTTVESVNDG
KQASWYMHRYIQSLYGAVVSTTPELPLFYTPIDLVDISVLMAGLKFPNPFGIASATPATS
SSMIRRAFEAGWGFAVTKTFSLDKDIVTNVSPRIVRGVTSGPIYGPGQGSFLNIELISEK
TAAYWCKSITELKSDFPKQILIASIMCSYSKDDWTELSKMAEAAGADALELNLSCPHGMG
ERGMGLACGQDPELVRNICRWVRQAVQIPFFAKLTPNVTDIVNIAVAAQEGGADGVTATN
TVSGLMGLKADGTPWPAVGAGLRTTYGGVSGNAIRPIALRAVSAIARALPGFPILATGGI
DSAESGLQFLHSGASVLQVCSAIQNQDFTVIDDYCTGLRALLYLKSIEELEDWNGQSPTT
MRHQKGKPVSGIADLIGKEDPSASWNTATPQKLPSFGPYLEQRKKIIAENKMKLKEQGTA
AVLPEKKHFIPKKPIPAIKDVIGKALQYIGTYGELCNTEQVVALIDEEMCINCGKCYMTC
NDSGYQAIQFDAETHLPTVTDSCTGCTLCLSVCPIIDCILMVPRTTPYEPRRGLPLALSP
LC
NT seq 2889 nt   +upstreamnt  +downstreamnt
atgagatgcttgaagtgtgcagatgccccctgtcagaagagttgcccaactaatctggac
atcaagtcattcatcacaagcattgcaaacaagaactattatggagctgccaaaatgatt
ttttctgacaatccacttggtctgacatgtggaatggtgtgtcctacatcagacctttgt
gttggtggctgcaatttgtatgctactgaggagggaccaattaatattggtggattgcag
cagtttgctactgaggtgttcaaagccatgaacattccacagatcagaaacccttccttg
ccttctccagaagatatgcctgaagcttatcatgtgaaaatagcacttcttggtgcaggg
cctgcaagtttaagttgtgcttcctttttggctcgattgggctattcaaacatcaccata
tttgaaaagcaggagtatgttggtggcttaagcgcatctgaaatccctcagttcagattg
ccatatgatgtagtgaattttgaagctgagcttatgaaggatctcggagtgaagataatt
tatagtaaagggcttgctgtggatggaatgacactccgtaccttgaaagaagatggctat
gaagcagtcttcattggaataggtttaccagaaccaaacagagacagtgtattccaaggg
ctgagaatggatcaaggattttacacatcaaaagacttcctacctttggtagctgtggca
agtaagccagggatgtgtgcctgtcagtctccattgccatcaatacatggaactgtgatt
gtacttggggcaggagacactgcttttgactgtgcaacatctgctttacgctgtggagct
cgtcgtgtgtttgtggtcttcagaaagggcttcactaatatcagggctgttccggaagag
atggaacttgcaaaagaagagaggtgtgaatttctgcctttcctctcccctcggaaagtt
gtacttagaagtggacatattgttgcaatggagtttgttcgaactgagcagggcagtgat
ggaaactggaaagaagatgaggatcaggttgttcgtctgaaagctgacgtggtgatcagc
gcctttggttcagttttgagtgactctaaagtcatagaggccatgacacctatcaagttt
aacagatggggtcttcctgaagtagatccagaaactatgcaaacgagtgaaccctgggtt
tttgcaggtggtgatatcagtggtcatgctaacactacagtggaatcagtaaatgatgga
aaacaagcctcttggtacatgcacagatacatacagtccttatatggtgctgtagtttct
actactccagaactaccactcttctatactcctatagatttagtagacatcagtgtatta
atggctggactgaagtttccaaatccttttggcattgccagtgcaactcctgctacaagt
tcttcaatgattcgaagagcttttgaagctggatggggctttgctgtcactaaaacgttc
tccctggacaaggatattgtgaccaatgtttctccaaggattgtgcgtggagttacttcg
ggtcccatctatggcccaggccaaggctcttttctaaacattgaactgatcagtgagaaa
acagcggcatattggtgtaaaagtattactgaactgaagagtgacttcccaaaacaaatc
ctgattgccagcatcatgtgcagctatagcaaggacgactggactgaactttcaaaaatg
gctgaggctgctggcgcagatgcactggagttaaatctatcatgtcctcatggcatgggg
gagagaggcatgggcctggcctgtgggcaggatccagagctggtgcggaacatctgtcgc
tgggttagacaagctgttcagattcctttctttgccaagctgaccccaaatgtcactgat
attgtgaatattgctgtggctgcgcaggaaggtggcgcagatggtgttacagccaccaac
acggtgtcaggactgatgggactcaaagcagacggcacaccttggccagcagttggtgca
ggactgaggaccacatatggtggtgtgtcaggaaatgctattaggcccatcgcgctccgt
gcagtgtctgctatagcccgtgctcttccaggatttcccatcttagcaactggaggcatt
gactctgctgaaagtggtctccagtttctgcacagtggagcttcagttttacaggtgtgc
agtgcaatccagaatcaagatttcactgttattgatgactactgcactggactgcgagct
cttctttacctgaaaagcattgaggaacttgaagactggaatggacagagtcctacaacc
atgcgccatcagaaaggaaaaccagtatctggaattgctgatctgataggaaaggaagac
ccatcagcctcctggaacactgcaaccccacagaaactacccagttttgggccttacctg
gaacaacgtaaaaaaattatagctgagaacaagatgaaactgaaggaacaaggcacagct
gctgtgcttcctgaaaaaaagcatttcattccaaagaagcccattccagcaatcaaggat
gtaattggaaaagcactgcagtatattggaacatatggtgagctctgcaacacagagcaa
gttgtggctctgattgatgaggaaatgtgtatcaactgtggcaaatgttacatgacctgt
aatgattccggctaccaggctatccagttcgatgccgaaacccacctgcccacggtcacc
gacagctgcacgggctgcaccctgtgcctcagcgtctgccccatcatcgactgcatcctc
atggttcccaggaccaccccgtatgagccccggcgagggctgcccctggccctgagcccc
ctgtgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (5)   
   KEGG MODULE (1)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   CGNC (1)   
   OC (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (16)   
   RefSeq(nuc) (12)   
   GenBank (2)   
   EMBL (2)   
Protein domain (19)   
   Pfam (19)   
All databases (79)   

Download RDF
DBGET integrated database retrieval system